D-AP4

Biological Activity

DL Mixture and L-isomer also available.

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Background References

1. Melanopsin is highly resistant to light and chemical bleaching in vivo.
   Sexton TJ, Golczak M, Palczewski K
   J. Biol. Chem., 2012;287(25):20888-97.
2. The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations.
   Evans et al.
   Br.J.Pharmacol., 1982;75:65
3. Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord.
   Davies and Watkins
   Brain Res., 1982;235:378
4. Utilization of the resolved L-isomer of 2-amino-6-phosphonhexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons.
   Schulte et al.
   Brain Res., 1994;649:203

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