GYY 4137 morpholine salt
Chemical Name: P-(4-Methoxyphenyl)-P-4-morpholinylphosphinodithioic acid morpholine salt
Biological Activity
GYY 4137 morpholine salt is a slow-releasing H2S donor. Exhibits vasodilator and antihypertensive activity. Activity causes slow dilation of blood vessels in vitro and in vivo; does not influence vascular smooth muscle cell viability in culture. Water-soluble.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137).
Li et al.
Circulation, 2008;117:2351 -
The effect of hydrogen sulfide donors on lipopolysaccaride-induced formation of inflammatory mediators in macrophages.
Whiteman et al.
Antioxid.Redox.Signal., 2010;12:1147 -
The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo.
Lee et al.
PLoS One, 2011;6:e21077 -
Hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E-/- mice.
Liu et al.
Br.J.Pharmacol. [Epub ahead of print], 2013;
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for GYY 4137 morpholine salt
The citations listed below are publications that use Tocris products. Selected citations for GYY 4137 morpholine salt include:
1 Citation: Showing 1 - 1
-
Hydrogen sulfide, oxygen, and calcium regulation in developing human airway smooth muscle.
Authors: Y S Et al.
FASEB J 2020;34:12991-13004
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for GYY 4137 morpholine salt
There are currently no reviews for this product. Be the first to review GYY 4137 morpholine salt and earn rewards!
Have you used GYY 4137 morpholine salt?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
