Human PLUNC Antibody Summary
Gln20-Val256
Accession # Q9NP55
Applications
This antibody functions as an ELISA detection antibody when paired with Mouse Anti-Human PLUNC Monoclonal Antibody (Catalog # MAB18971).
This product is intended for assay development on various assay platforms requiring antibody pairs.
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: PLUNC
PLUNC, also named SPLUNC1, is a secreted protein that is expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. It is structurally related to bactericidal/permeability-increasing protein (BPI) and lipopolysaccaride binding protein (LBP), which are central to the host defense against gram-negative bacteria. PLUNC belongs to the short subfamily of PLUNC family proteins and have homology only to the N-terminal domains of BPI. PLUNC may function in the innate immune response against bacteria.
Product Datasheets
Citations for Human PLUNC Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 4
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SPLUNC1 is a negative regulator of the Orai1 Ca2+ channel
Authors: T Wu, AS Goriounova, EN Worthingto, JA Wrennall, A Ghosh, S Ahmad, M Flori Sass, R Tarran
Physiological Reports, 2022-05-01;10(10):e15306.
Species: Human
Sample Types: Whole Cells
Applications: Immunoprecipitation -
A Rare Mutation in SPLUNC1 Affects Bacterial Adherence and Invasion in Meningococcal Disease
Authors: Bayarchimeg Mashbat, Evangelos Bellos, Stephanie Hodeib, Fadil Bidmos, Ryan S Thwaites, Yaxuan Lu et al.
Clinical Infectious Diseases
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Airway symptoms and biological markers in nasal lavage fluid in subjects exposed to metalworking fluids.
Authors: Fornander L, Graff P, Wahlen K, Ydreborg K, Flodin U, Leanderson P, Lindahl M, Ghafouri B
PLoS ONE, 2013-12-31;8(12):e83089.
Species: Human
Sample Types: Nasal Lavage Fluid
Applications: Western Blot -
Quantitation of SPLUNC1 in saliva with an xMAP particle-based antibody capture and detection immunoassay
Authors: Karl G. Kohlgraf, Abbey R. Ackermann, Kindra K. Burnell, Rupasree N. Srikantha, Sophie A. Joly, Jennifer A. Bartlett et al.
Archives of Oral Biology
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