L-Kynurenine

Tocris Bioscience | Catalog # 4393

Tryptophan catabolite; endogenous aryl hydrocarbon receptor ligand
Tocris Bioscience
Discontinued Product
4393 has been discontinued. View all Other Tryptophan 2,3 Dioxygenase Compounds products.

Key Product Details

Description

Tryptophan catabolite; endogenous aryl hydrocarbon receptor ligand
View all Other Tryptophan 2,3 Dioxygenase Compounds »

Product Description

L-Kynurenine is a tryptophan catabolite; endogenous activator of the aryl hydrocarbon receptor (AhR). Immunosuppressant; suppresses allogeneic T cell proliferation.

Product Specifications for L-Kynurenine

Molecular Weight

208.21

Formula

C10H12N2O3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS Number

2922-83-0

PubChem ID

161166

InChI Key

YGPSJZOEDVAXAB-QMMMGPOBSA-N

SMILES

O=C(C[C@H](N)C(O)=O)C1=C(N)C=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 2.08 10
DMSO 2.08 10

Preparing Stock Solutions for L-Kynurenine

The following data is based on the product molecular weight 208.21.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 48.03 mL 240.14 mL 480.28 mL
0.5 mM 9.61 mL 48.03 mL 96.06 mL
1 mM 4.80 mL 24.01 mL 48.03 mL
5 mM 0.96 mL 4.80 mL 9.61 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 10 publications citing the usage of this product.

Product Documents for L-Kynurenine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for L-Kynurenine

For research use only

Customer Reviews for L-Kynurenine (2)

5 out of 5
2 Customer Ratings
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4 Stars
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2 Stars
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1 Stars
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  • Happy with purchase
    Name: Anonymous
    Assay Type: In Vitro
    Verified Customer | Posted 08/20/2018
    Compound was clean and active in cell based assays. Dissolved in DMSO or HCL.
  • IDO assay standard (L-Kynurenine)
    Name: Debanjan Mukhopadhyay
    Species: Human
    Assay Type: Ex Vivo
    Cell Line/Tissue: Human foreskin fibroblast
    Verified Customer | Posted 01/11/2018
    This product is very pure and you can use it from a range of 5 uM to 1500 uM.
    I use this product as a standard for Indoleamine 2,3 dioxygenase assay. This product worked excellent as a standard for Tryptophan catabolism assay.

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