M 1145
Biological Activity
M 1145 is a potent and selective galanin receptor 2 (GAL2) agonist (EC50 = 38 nM, Ki values are 6.55, 497 and 587 nM at GAL2, GAL3 and GAL1 respectively). Has an additive effect on the signal transduction of galanin.Technical Data
(Modifications: Ala-27 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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Background References
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A novel GalR2-specific peptide agonist.
Runesson et al.
Neuropeptides, 2009;43:187
Product Datasheets
Citation for M 1145
The citations listed below are publications that use Tocris products. Selected citations for M 1145 include:
1 Citation: Showing 1 - 1
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Central galanin receptor 2 mediates galanin action to promote systemic glucose metabolism of type 2 diabetic rats.
Authors: Fang
Biochem Pharmacol 2018;156:241
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