Mouse Lysyl Oxidase/LOX (NP_034858) VersaClone cDNA

Name: Mouse Lysyl Oxidase/LOX (NP_034858) VersaClone cDNA
Brand: R&D Systems
SKU: RDC2688
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC2688

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species

Mouse

Accession Number

NP_034858

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Lysyl Oxidase/LOX

Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. LOX plays a vital role in the formation and repair of the extracellular matrix. In addition, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, Lysyl oxidase is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.

Long Name

Lysyl Oxidase

Alternate Names

AAT10

Entrez Gene IDs

4015 (Human); 16948 (Mouse); 102132184 (Cynomolgus Monkey)

Gene Symbol

LOX

UniProt

NP_034858

Additional Lysyl Oxidase/LOX Products

Product Documents for Mouse Lysyl Oxidase/LOX (NP_034858) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Mouse Lysyl Oxidase/LOX (NP_034858) VersaClone cDNA

For research use only

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