MY-5445

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation.
   Hagiwara et al.
   J.Pharmacol.Exp.Ther., 1984;228:467
3. Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase, basic and potential clinical applications.
   Hidaka and Endo et al.
   Adv.Cyclic Nucleotide Protein Phosphorylation Res., 1984;16:245

Product Datasheets