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Neuropathiazol

Catalog #: 5186 Datasheet / COA / SDS

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Neuropathiazol | CAS No. 880090-88-0 | Compounds for Stem Cell Differentiation
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Description: Selective inducer of neuronal differentiation in hippocampal neural progenitors

Chemical Name: Ethyl 4-[methyl-(2-phenyl-1,3-thiazol-4-yl)amino]benzoate

Purity: ≥98%

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Biological Activity

Neuropathiazol is a selective inducer of neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs). Selectively suppresses astrocyte differentiation when induced by LIF, BMP2 and FBS compared to retinoic acid. Enhances maturation of NPC derived neurons.

Technical Data

M.Wt:
338.42
Formula:
C19H18N2O2S
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
880090-88-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells.
    Warashina et al.
    Angew Chem. Int. Ed. Engl., 2006;45:591

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