OAC-2
Discontinued Product
6066 has been discontinued.
View all Additional Stem Cell Dedifferentiation Products products.
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Description: Oct4 activator; enhances iPSC reprogramming efficiency
Chemical Name: N-(1H-Indol-5-yl)benzamide
Purity: ≥98%
Biological Activity
OAC-2 is an Oct 4 activator; enhances iPSC reprogramming four-fold and accelerates the appearance of iPSC colonies in combination with 4F (Oct4, Sox2, c-Myc and Klf4). Also induces cardiomyocyte-like cells from human fibroblasts, as part of the 9C cocktail (CHIR99021, A83-01, BIX01294, AS83541, SC1, Y27632, SU 16f, JNJ10198409 and OAC-2)Technical Data
M.Wt:
236.27
Formula:
C15H12N2O
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
6019-39-2
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Conversion of human fibroblasts into functional cardiomyocytes by small molecules.
Cao et al.
Science, 2016;352:6290 -
Identification of Oct4-activating compounds that enhance reprogramming efficiency.
Li et al.
Proc.Natl.Acad.Sci.USA., 2012;109:20853
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