OLDA
Chemical Name: (9Z)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-9-octadecenamide
Purity: ≥98%
Biological Activity
OLDA is a potent endogenous vanilloid TRPV1 (VR1) receptor agonist (EC50 = 36 nM at hVR1) with low affinity for rCB1 receptors (Ki = 1.6 μM). Potently induces VR1-mediated thermal hyperalgesia in rats in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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N-OleoylDA, a novel endogenous capsaicin-like lipid that produces hyperalgesia.
Chu et al.
J.Biol.Chem., 2003;278:13633 -
Anitallodynic effects of loperamide and fentanyl against topical capsaicin-induced allodynia in unanesthetized primates.
Butelman et al.
J.Pharmacol.Exp.Ther., 2004;311:155 -
Anitallodynic effects of loperamide and fen. against topical capsaicin-induced allodynia in unanesthetized primates.
Butelman et al.
J.Pharmacol.Exp.Ther., 2004;311:155
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