PAF (C16)

Tocris Bioscience | Catalog # 2940

Endogenous platelet-activating factor (PAF)
Tocris Bioscience

Key Product Details

Description

Endogenous platelet-activating factor (PAF)

Alternative Names

Platelet-activating factor
View all Platelet-activating Factor (PAF) Receptor Agonists »

Product Description

PAF (C16) is an endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.

Product Specifications for PAF (C16)

Molecular Weight

523.68

Formula

C26H54NO7P

Storage

Store at -20°C

Chemical Name

(7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide

CAS Number

74389-68-7

PubChem ID

108156

InChI Key

HVAUUPRFYPCOCA-AREMUKBSSA-N

SMILES

CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COCCCCCCCCCCCCCCCC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 52.37 100

Preparing Stock Solutions for PAF (C16)

The following data is based on the product molecular weight 523.68.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.91 mL 9.55 mL 19.10 mL
5 mM 0.38 mL 1.91 mL 3.82 mL
10 mM 0.19 mL 0.95 mL 1.91 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

Product Documents for PAF (C16)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PAF (C16)

For research use only

Customer Reviews for PAF (C16) (1)

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  • Platelet activating factor (PAF)
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: microglia
    Verified Customer | Posted 05/02/2018
    Platelet activating factor (PAF) at 100nM induced a biphasic calcium response in microglia culture. Initial release from internal source and subsequent a sustained influx.

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