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Porcine IFN-alpha Antibody

Catalog #: 27105-1
9 Citations Datasheet / COA / SDS
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27105-1
Product Details
Citations (9)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Porcine IFN-alpha Antibody Summary

Species Reactivity
Porcine
Specificity
Neutralizes pig interferon alpha
Source
Monoclonal Mouse IgG1 Clone # F17
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Porcine IFN-alpha
Formulation
Supplied as a liquid
Endotoxin Level
<1.0 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Neutralization

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
After receipt, this product should be kept at -20°C for retention of full activity. Do not store below -20°C.

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

References
  1. L'Haridon, R.M. et al. 1991, Hybridoma 10: 35-47.
  2. Splichal, I. et al. 1994, Immunology Letters 43:203-208.
Long Name
Interferon alpha
Entrez Gene IDs
3440 (Human)
Alternate Names
IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2; LeIF D

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Citations for Porcine IFN-alpha Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

9 Citations: Showing 1 - 9
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  1. Comparative Sequence Analysis of Historic and Current Porcine Rotavirus C Strains and Their Pathogenesis in 3-Day-Old and 3-Week-Old Piglets
    Authors: J Chepngeno, S Takanashi, A Diaz, H Michael, FC Paim, MC Rahe, JR Hayes, C Baker, D Marthaler, LJ Saif, AN Vlasova
    Front Microbiol, 2020-04-24;11(0):780.
    Species: Porcine
    Sample Types: Serum
    Applications: ELISA Detection
  2. Porcine cathelicidins efficiently complex and deliver nucleic acids to plasmacytoid dendritic cells and can thereby mediate bacteria-induced IFN-alpha responses.
    Authors: Baumann A, Demoulins T, Python S, Summerfield A
    J Immunol, 2014-06-04;193(1):364-71.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Innate immune responses to human rotavirus in the neonatal gnotobiotic piglet disease model
    Authors: Ana M. González, Marli S. P. Azevedo, Kwonil Jung, Anastasia Vlasova, Wei Zhang, Linda J. Saif
    Immunology
  4. Cytokine protein expression levels in tracheobronchial lymph node homogenates of pigs infected with pseudorabies virus.
    Authors: Miller LC, Zanella EL, Waters WR
    Clin. Vaccine Immunol., 2010-03-10;17(5):728-34.
    Species: Porcine
    Sample Types: Tissue Homogenates
    Applications: ELISA Development
  5. The leader proteinase of foot-and-mouth disease virus inhibits the induction of beta interferon mRNA and blocks the host innate immune response.
    Authors: de Los Santos T, de Avila Botton S, Weiblen R, Grubman MJ
    J. Virol., 2006-02-01;80(4):1906-14.
    Species: Porcine
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  6. Fc gamma RII-dependent sensitisation of natural interferon-producing cells for viral infection and interferon-alpha responses.
    Authors: Balmelli C, Vincent IE, Rau H, Guzylack-Piriou L, McCullough K, Summerfield A
    Eur. J. Immunol., 2005-08-01;35(8):2406-15.
    Species: Porcine
    Sample Types: Serum
    Applications: ELISA Development
  7. Porcine reproductive and respiratory syndrome virus field isolates differ in in vitro interferon phenotypes.
    Authors: Lee SM, Schommer SK, Kleiboeker SB
    Vet. Immunol. Immunopathol., 2004-12-08;102(3):217-31.
    Species: Porcine
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  8. Classical swine fever virus induces proinflammatory cytokines and tissue factor expression and inhibits apoptosis and interferon synthesis during the establishment of long-term infection of porcine vascular endothelial cells.
    Authors: Bensaude E, Turner JL, Wakeley PR, Sweetman DA, Pardieu C, Drew TW, Wileman T, Powell PP
    J. Gen. Virol., 2004-04-01;85(0):1029-37.
    Species: Porcine
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  9. Immediate protection of swine from foot-and-mouth disease: a combination of adenoviruses expressing interferon alpha and a foot-and-mouth disease virus subunit vaccine.
    Authors: Moraes MP, Chinsangaram J, Brum MC, Grubman MJ
    Vaccine, 2003-12-12;22(2):268-79.
    Species: Porcine
    Sample Types: Plasma
    Applications: ELISA Development

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