(R)-CE3F4
Chemical Name: (2R)-5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde
Purity: ≥98%
Biological Activity
(R)-CE3F4 is an Epac inhibitor (IC50 values are 4.2 and 44 μM for Epac1 and Epac2(B), respectively). Blocks activation of Epac by cAMP. This is the R-enantiomer of CE3F4 (Cat.No.4793).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
Mechanism of selective enzyme inhibition through uncompetitive regulation of an allosteric agonist.
Boulton et al.
J.Am.Chem.Soc., 2018;140:9624 -
The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1).
Courilleau et al.
Biochem.Biophys.Res.Commun., 2013;440:443
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for (R)-CE3F4
There are currently no reviews for this product. Be the first to review (R)-CE3F4 and earn rewards!
Have you used (R)-CE3F4?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
