Rivastigmine tartrate

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by two series of novel carbamates.
   Groner et al.
   Mol.Pharmacol., 2007;71:1610
2. Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine.
   Luo et al.
   J.Med.Chem., 2006;49:2174
3. New acetylcholinesterase inhibitors for Alzheimer's disease.
   Mehta et al.
   Int.J.Alzheimers Dis, 2012;
4. Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons.
   Bailey et al.
   PLoS One, 2011;6:e21954

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