RS 09
Tocris Bioscience | Catalog # 5928
TLR4 peptide agonist; acts as an adjuvant in vivo
Discontinued Product
5928 has been discontinued.
View all Toll-like Receptor Agonists products.
Key Product Details
Description
TLR4 peptide agonist; acts as an adjuvant in vivo
Product Description
RS 09 is a TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.
Product Specifications for RS 09
Molecular Weight
691.78
Formula
C31H49N9O9
Storage
Store at -20°C
CAS Number
1449566-36-2
PubChem ID
121513902
InChI Key
SHYNPSTXGFDOBD-HRALPVODSA-N
SMILES
[H]N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 2mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product.
- Shanmugam Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. PLoS One 2012 PMID: 22363498
- Li Intranasal vaccination against HIV-1 with adenoviral vector-based nanocomplex using synthetic TLR-4 agonist peptide as adjuvant. Mol.Pharm. 2016 PMID: 26824411
Product Documents for RS 09
Product Specific Notices for RS 09
For research use only
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