Home / Calcium Binding Protein Modulator Inhibitors / SGC CAMKK2-1

SGC CAMKK2-1

Catalog #: 7877 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7877/10
SGC CAMKK2-1 | CAS No. 2561494-76-4 | Calcium Binding Protein Modulator Inhibitors
1 Image
Description: Potent and selective CAMKK1/2 inhibitor

Chemical Name: 2-Cyclopentyl-4-[5-(3-methylphenyl)furo[2,3-b]pyridin-3-yl]benzoic acid

Purity: ≥95%

Product Details
Reviews
Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

SGC CAMKK2-1 is a potent and selective Ca2+-calmodulin-dependent protein kinase kinase (CaMKK) inhibitor (CAMKK2 IC50 = 30 nM). Displays selectivity toward CAMKK1 and CAMKK2 over 404 kinases in a kinome wide screen (Discoverx). SGC CAMKK2-1 inhibits AMPK phosphorylation in C4-2 prostate cancer cells (IC50 = 1.6 μM).

Technical Data

M.Wt:
397.47
Formula:
C26H23NO3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2561494-76-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC CAMKK2-1 probe summary on the SGC website.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for SGC CAMKK2-1

There are currently no reviews for this product. Be the first to review SGC CAMKK2-1 and earn rewards!

Have you used SGC CAMKK2-1?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.