ST 91

Name: ST 91
Brand: Tocris Bioscience
SKU: 2638
Price: 147 USD

Catalog #: 2638
1 Citation Datasheet / COA / SDS

Discontinued Product

2638 has been discontinued.

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ST 91 | CAS No. 4749-61-5 | Adrenergic alpha-2 Receptor Agonists

1 Image

Description: α2 agonist, putative α2C agonist

Chemical Name: N-(2,6-Diethylphenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride

Purity: ≥99%

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Product Details

Citations (1)

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

ST 91 is an α₂-adrenoceptor agonist that does not cross the blood brain barrier. Displays ~ 120-fold selectivity for α₂ receptors over α₁ receptors and acts predominantly at non-α_2A-adrenoceptors which may be of the α_2C subtype. Antinociceptive; increases tail-flick latencies in Sasco and Harlan rats.

Technical Data

M.Wt:

253.77

Formula:

C₁₃H₁₉N₃.HCl

Solubility:

Soluble to 100 mM in water and to 100 mM in DMSO

Purity:

≥99%

Storage:

Desiccate at +4°C

CAS No:

4749-61-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Characterization of the pharmacology of intrathecally administered alpha-2 agonists and antagonists in rats.
Takano and Yaksh
J.Pharmacol.Exp.Ther., 1992;261:764
Cardiopulmonary effects of the α₂-adrenoceptor agonists medetomidine and ST-91 in anesthetized sheep.
Celly et al.
J.Pharmacol.Exp.Ther., 1999;289:712
Synergistic interactions between two α₂-adrenoceptor agonists, dexmedetom. and ST-91, in two substrains of Sprague-Dawley rats.
Graham et al.
Pain, 2000;85:135

Product Datasheets

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SDS

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Citation for ST 91

The citations listed below are publications that use Tocris products. Selected citations for ST 91 include:

1 Citation: Showing 1 - 1

Icilin-evoked behavioral stimulation is attenuated by alpha₂-adrenoceptor activation.
Authors: Kim Et al.
Brain Res 2011;1384:110

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