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TAC

Catalog #: 8825 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8825/50
8825/10
TAC | CAS No. 666699-46-3 | TERT
1 Image
Description: TERT activator

Chemical Name: N-(3-Chloro-4-fluorophenyl)-4-fluoro-3,5-dimethylbenzenesulfonamide

Purity: ≥98%

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Biological Activity

TAC is a telomerase reverse transcriptase (TERT) activator. TAC upregulates TERT gene transcription via the MEK/ERK/AP-1 cascade. In primary human cells and naturally aged mice, TAC enhances telomere synthesis, reduces tissue aging markers, cellular senescence, and inflammatory cytokines. In the brain, TAC induces neurogenesis, reduces neuroinflammation, and preserves cognitive function.

Technical Data

M.Wt:
331.76
Formula:
C14H12ClF2NO2S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
666699-46-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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