Travaprost
Tocris Bioscience | Catalog # 4218
Potent and selective FP prostaglandin receptor agonist
Discontinued Product
4218 has been discontinued.
View all Prostanoid Receptor Agonists products.
Key Product Details
Description
Potent and selective FP prostaglandin receptor agonist
Product Description
Travaprost is a FP prostaglandin receptor agonist. Exhibits submicromolar affinity for DP, EP, IP and TP receptors. Stimulates intracellular Ca2+ mobilization. Ocular hypotensive agent.
Product Specifications for Travaprost
Molecular Weight
500.55
Formula
C26H35F3O6
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methyethyl ester
CAS Number
157283-68-6
PubChem ID
5282226
InChI Key
MKPLKVHSHYCHOC-AHTXBMBWSA-N
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2)[C@H](O)C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 10mg/ml) |
Calculators
Background References
References are publications that support the biological activity of the product.
- Sharif [3H]AL-5848 ([3H]9beta-(+)-Fluprostenol). Carboxylic acid of travo. (AL-6221), a novel FP prostaglandin to study the pharmacology and autoradiographic localization of the FP receptor. J.Pharm.Pharmacol. 1999 PMID: 10454045
- Hellberg Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J.Ocul.Pharmacol.Ther. 2001 PMID: 11765147
Product Documents for Travaprost
Product Specific Notices for Travaprost
For research use only
Related Research Areas
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