VH 032 amide-alkylC9-acid

Tocris Bioscience | Catalog # 7404

VHL ligand with alkyl linker and terminal acid for onward chemistry
Tocris Bioscience

Key Product Details

Description

VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternative Names

(S,R,S)-AHPC-C9-COOH
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Product Description

Functionalized von-Hippel-Lindau protein (VHL) ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC9 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications for VH 032 amide-alkylC9-acid

Molecular Weight

628.83

Formula

C33H48N4O6S

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

11-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecanoic acid

CAS Number

2172819-78-0

PubChem ID

134184031

InChI Key

MTQZLQCVZFDQOZ-DIIXFEDBSA-N

SMILES

CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(CCCCCCCCCC(O)=O)=O)=O)O)=O)SC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

There are currently no references for this product.

Product Documents for VH 032 amide-alkylC9-acid

Certificate of Analysis

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Product Specific Notices for VH 032 amide-alkylC9-acid

For research use only

Citations for VH 032 amide-alkylC9-acid

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