Human CXCL12/SDF-1 alpha Quantikine ELISA Kit Summary
Product Summary
Precision
Cell Culture Supernates, EDTA Plasma, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 40 | 40 | 40 |
Mean (pg/mL) | 491 | 1700 | 3420 | 544 | 1600 | 3150 |
Standard Deviation | 19 | 58 | 115 | 73 | 150 | 257 |
CV% | 3.9 | 3.4 | 3.4 | 13.4 | 9.4 | 8.2 |
Recovery
The recovery of SDF-1 alpha spiked to three different levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Media (n=4) | 101 | 95-108 |
Platelet-poor EDTA Plasma (n=5) | 97 | 90-107 |
Platelet-poor Heparin Plasma (n=5) | 97 | 90-104 |
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: CXCL12/SDF-1 alpha
CXCL12/Stromal Cell-derived Factor 1 (SDF-1) is a member of the CXC chemokine ligand superfamily. Six alternatively spliced CXCL12/SDF-1 isoforms have been identified including, CXCL12/SDF-1 alpha, CXCL12/SDF-1 beta, and CXCL12/SDF-1 gamma. CXCL12/SDF-1 alpha is 89 amino acids (aa) in length with a predicted molecular weight of 10 kDa, CXCL12/SDF-1 beta is 93 aa in length with a predicted molecular weight of 10.6 kDa, and CXCL12/SDF-1 gamma is 119 aa in length with a predicted molecular weight of 13.7 kDa. The mouse CXCL12/SDF-1 orthologs share 99% aa sequence identity with the human protein. The alpha and beta isoforms are ubiquitously expressed while the gamma isoform is primarily expressed in the heart. CXCL12/SDF-1 isoforms are chemotactic for T lymphocytes and monocytes. It is cardio protective and has also been shown to hinder CXCR4-mediated HIV infection of T cells.
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 100 µL of Assay Diluent to each well.
- Add 100 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours on a horizontal orbital microplate shaker.
- Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.
- Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours on the shaker.
- Aspirate and wash 4 times.
- Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes on the benchtop. PROTECT FROM LIGHT.
- Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Human CXCL12/SDF-1 alpha Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Circulating Polymorphonuclear Myeloid-Derived Suppressor Cells (PMN-MDSCs) Have a Biological Role in Patients with Primary Myelofibrosis
Authors: Campanelli, R;Carolei, A;Catarsi, P;Abbà, C;Boveri, E;Paulli, M;Gentile, R;Morosini, M;Albertini, R;Mantovani, S;Massa, M;Barosi, G;Rosti, V;
Cancers
Species: Human
Sample Types: Platelet-poor Plasma
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Advantages of pooling of human bone marrow-derived mesenchymal stromal cells from different donors versus single-donor MSCs
Authors: Kannan, S;Gokul Krishna, S;Gupta, PK;Kolkundkar, UK;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
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C1q/Tumor Necrosis Factor-Related Protein-9 Is a Novel Vasculoprotective Cytokine That Restores High Glucose-Suppressed Endothelial Progenitor Cell Functions by Activating the Endothelial Nitric Oxide Synthase
Authors: Hu, Q;Qu, W;Zhang, T;Feng, J;Dong, X;Nie, R;Chen, J;Wang, X;Peng, C;Ke, X;
Journal of the American Heart Association
Species: Human
Sample Types: Cell Culture Supernates
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Ionizing radiation normalizes the features of active breast cancer stromal fibroblasts and suppresses their paracrine pro-carcinogenic effects
Authors: Aboussekhra, A;Alraouji, NN;Al-Mohanna, FH;Al-Khalaf, H;
Translational oncology
Species: Human
Sample Types: Cell Culture Supernates
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WHIM Syndrome-linked CXCR4 mutations drive osteoporosis
Authors: A Anginot, J Nguyen, Z Abou Nader, V Rondeau, A Bonaud, M Kalogeraki, A Boutin, JP Lemos, V Bisio, J Koenen, L Hanna Doum, A Picart, A Coudert, S Provot, N Dulphy, M Aurrand-Li, SJC Mancini, G Lazennec, DH McDermott, F Guidez, C Blin-Wakka, PM Murphy, M Cohen-Sola, M Espéli, M Rouleau, K Balabanian
Nature Communications, 2023-04-12;14(1):2058.
Species: Human
Sample Types: Cell Culture Supernates
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Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS
Authors: LJ Pallett, L Swadling, M Diniz, AA Maini, M Schwabenla, AD Gasull, J Davies, S Kucykowicz, JK Skelton, N Thomas, NM Schmidt, OE Amin, US Gill, KA Stegmann, AR Burton, E Stephenson, G Reynolds, M Whelan, J Sanchez, R de Maeyer, C Thakker, K Suveizdyte, I Uddin, AM Ortega-Pri, C Grant, F Froghi, G Fusai, S Lens, S Pérez-Del-, W Al-Akkad, G Mazza, M Noursadegh, A Akbar, PTF Kennedy, BR Davidson, M Prinz, BM Chain, M Haniffa, DW Gilroy, M Dorner, B Bengsch, A Schurich, MK Maini
Nature, 2023-01-25;614(7947):334-342.
Species: Human
Sample Types: Cell Culture Supernates
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Serum Levels of Stromal Cell-Derived Factor-1alpha and Vascular Endothelial Growth Factor Predict Clinical Outcomes in Head and Neck Squamous Cell Carcinoma Patients Receiving TPF Induction Chemotherapy
Authors: YH Chen, CY Chien, YM Wang, SH Li
Biomedicines, 2022-03-29;10(4):.
Species: Human
Sample Types: Serum
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Myometrial-derived CXCL12 promotes lipopolysaccharide induced preterm labour by regulating macrophage migration, polarization and function in mice
Authors: L Zhang, R Mamillapal, S Habata, M McAdow, HS Taylor
Journal of Cellular and Molecular Medicine, 2022-03-23;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Clinical relevance of circulating angiogenic cells in patients with ischemic stroke
Authors: F Rodríguez-, LB Torres-Mat, JC López-Fern, L Cappiello, JM González-M, B Clavo, JA Serna-Góme, L Estupiñán-, C Torres-Asc, J Villar
BMC cardiovascular disorders, 2022-03-21;22(1):118.
Species: Human
Sample Types: Plasma
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Plasma proteome changes linked to late phase response after inhaled allergen challenge in asthmatics
Authors: M Weitoft, M Kadefors, H Stenberg, E Tufvesson, Z Diamant, S Rolandsson, L Bjermer, O Rosmark, G Westergren
Respiratory Research, 2022-03-05;23(1):50.
Species: Human
Sample Types: Plasma
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MiRNA126 - RGS16 - CXCL12 Cascade as a Potential Mechanism of Acute Exercise-Induced Precursor Cell Mobilization
Authors: M Schmid, HC Martins, G Schratt, JM Kröpfl, CM Spengler
Frontiers in Physiology, 2021-12-09;12(0):780666.
Species: Human
Sample Types: Plasma
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Preferential interaction of platelets with prostate cancer cells with stem cell markers
Authors: JK Rudzinski, NP Govindasam, A Asgari, MS Saito, JD Lewis, P Jurasz
Thrombosis Research, 2021-08-12;206(0):42-51.
Species: Human
Sample Types: Cell Culture Supernates
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Adipose-derived mesenchymal stem cells preserve cardiac function via ANT-1 in dilated cardiomyopathy hamster model
Authors: D Mori, S Miyagawa, T Kido, H Hata, T Ueno, K Toda, T Kuratani, M Oota, K Kawai, H Kurata, H Nishida, Y Sawa
Regenerative Therapy, 2021-07-09;18(0):182-190.
Species: Human
Sample Types: Cell Culture Supernates
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Targeting HIF-1alpha Regulatory Pathways as a Strategy to Hamper Tumor-Microenvironment Interactions in CLL
Authors: C Vitale, V Griggio, C Riganti, M Todaro, J Kopecka, R Jones, C Salvetti, E Boccellato, F Perutelli, C Voena, L Godio, M Boccadoro, M Coscia
Cancers, 2021-06-09;13(12):.
Species: Human
Sample Types: Serum
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Complex Coronary Instent Chronic Total Occlusion Lesions: Oxidative Stress, Inflammation, and Coronary Stent Lengths
Authors: X Li, D Guo, Y Chen, Y Hu, F Zhang
Oxidative Medicine and Cellular Longevity, 2021-04-15;2021(0):8815048.
Species: Human
Sample Types: Plasma
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G-CSF treatment of healthy pediatric donors affects their hematopoietic microenvironment through changes in bone marrow plasma cytokines and stromal cells
Authors: F Aerts-Kaya, E Kilic, S Köse, G Aydin, I Cagnan, B Kuskonmaz, D Uckan-Ceti
Cytokine, 2020-12-28;139(0):155407.
Species: Human
Sample Types: Plasma
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Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral Sclerosis
Authors: P Andrés-Ben, M Povedano, R Domínguez, C Marco, MJ Colomina, Ó López-Pére, I Santana, I Baldeiras, S Martínez-Y, I Zerr, F Llorens, J Fernández-, E Santamaría, I Ferrer
Int J Mol Sci, 2020-11-17;21(22):.
Species: Human
Sample Types: CSF
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Influence of reaming intramedullary nailing on MSC population after surgical treatment of patients with long bone fracture
Authors: I Sperelakis, E Tsitoura, C Koutoulaki, S Mastrodimo, TH Tosounidis, H Dimitriou, DA Spandidos, KM Antoniou, G Kontakis
Mol Med Rep, 2020-07-09;22(3):2521-2527.
Species: Human
Sample Types: Serum
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The CXCR4 Antagonist, AMD3100, Reverses Mesenchymal Stem Cell-Mediated Drug Resistance in Relapsed/Refractory Acute Lymphoblastic Leukemia
Authors: S Wang, X Wang, S Liu, S Zhang, X Wei, Y Song, Q Yin
Onco Targets Ther, 2020-07-06;13(0):6583-6591.
Species: Human
Sample Types: Cell Culture Supernates
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Knock-out of Hopx disrupts stemness and quiescence of hematopoietic stem cells in mice
Authors: CC Lin, CY Yao, YC Hsu, HA Hou, CT Yuan, YH Li, CJ Kao, PH Chuang, YC Chiu, Y Chen, WC Chou, HF Tien
Oncogene, 2020-06-12;0(0):.
Species: Human
Sample Types: Plasma
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SOX4 activates CXCL12 in hepatocellular carcinoma cells to modulate endothelial cell migration and angiogenesis in vivo
Authors: CN Tsai, SC Yu, CW Lee, JS Pang, CH Wu, SE Lin, YH Chung, CL Tsai, SY Hsieh, MC Yu
Oncogene, 2020-05-13;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Role of Vitamins A and D in BCR-ABL Arf-/- Acute Lymphoblastic Leukemia
Authors: K Annu, C Cline, K Yasuda, S Ganguly, A Pesch, B Cooper, L Janke, M Payton, K Mukherjee, SL Surman, JL Hurwitz, EG Schuetz
Sci Rep, 2020-02-11;10(1):2359.
Species: Human, Mouse
Sample Types: Cell Culture Media, Serum
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Foam cells promote atherosclerosis progression by releasing CXCL12
Authors: L Li, Z Du, B Rong, D Zhao, A Wang, Y Xu, H Zhang, X Bai, J Zhong
Biosci. Rep., 2020-01-31;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Association of chemokine expression in anterior cruciate ligament deficient knee with patient characteristics: Implications for post-traumatic osteoarthritis
Authors: L Ding, A Amendola, B Wolf, M Bollier, J Albright, Q Wang, M Wu, X Wang, H Song, D Pedersen, J Martin
Knee, 2019-11-11;0(0):.
Species: Human
Sample Types: Synovial Fluid
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Multilevel defects in the hematopoietic niche in essential thrombocythemia
Authors: T Sun, M Ju, X Dai, H Dong, W Gu, Y Gao, R Fu, X Liu, Y Huang, W Liu, Y Chi, W Wang, H Li, Y Zhou, L Shi, R Yang, L Zhang
Haematologica, 2019-07-09;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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CXCR4 in human osteosarcoma malignant progression. The response of osteosarcoma cell lines to the fully human CXCR4 antibody MDX1338
Authors: S Pollino, E Palmerini, B Dozza, E Bientinesi, M Piccinni-L, E Lucarelli, A Righi, MS Benassi, L Pazzaglia
J Bone Oncol, 2019-05-08;17(0):100239.
Species: Human
Sample Types: Cell Culture Supernates
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Ginsenoside Rg1 Accelerates Paracrine Activity and Adipogenic Differentiation of Human Breast Adipose-Derived Stem Cells in a Dose-Dependent Manner In Vitro
Authors: ZJ Liang, X Lu, DD Zhu, XL Yi, FX Wu, N He, C Tang, CY Wei, HM Li
Cell Transplant, 2019-01-24;0(0):9636897198256.
Species: Human
Sample Types: Cell Culture Supernates
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Assessment of agonistic and antagonistic properties of widely used oral care antimicrobial substances toward steroid estrogenic and androgenic receptors
Authors: K Michalíkov, L Linhartová, M Ezechiáš, T Cajthaml
Chemosphere, 2018-11-02;217(0):534-541.
Species: Human
Sample Types: Cell Culture Supernates
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Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin increases the activation of aryl hydrocarbon receptor and is associated with the aggressiveness of osteosarcoma MG-63 osteoblast-like cells
Authors: SC Yang, CH Wu, YK Tu, SY Huang, PC Chou
Oncol Lett, 2018-07-06;16(3):3849-3857.
Species: Human
Sample Types: Cell Culture Supernates
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miR-10a rejuvenates aged human mesenchymal stem cells and improves heart function after myocardial infarction through KLF4
Authors: J Dong, Z Zhang, H Huang, P Mo, C Cheng, J Liu, W Huang, C Tian, C Zhang, J Li
Stem Cell Res Ther, 2018-05-30;9(1):151.
Species: Human
Sample Types: Cell Culture Supernates
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The homing of bone marrow stem cells is differentially activated in ischemic and valvular heart�diseases and influenced by beta-blockers
Authors: M Kristochec, LD Dias, C Ghem, B Eibel, RAK Kalil, MM Markoski
J Transl Med, 2018-05-21;16(1):133.
Species: Human
Sample Types: Plasma
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Pro-angiogenic impact of SDF-1? gene-activated collagen-based scaffolds in stem cell driven angiogenesis
Authors: AL Laiva, RM Raftery, MB Keogh, FJ O'Brien
Int J Pharm, 2018-03-17;544(2):372-379.
Species: Human
Sample Types: Cell Culture Supernates
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Mobilization of progenitor cells and assessment of vessel healing after second generation drug-eluting stenting by optical coherence tomography
Authors: M Sakuma, T Nasuno, S Abe, S Obi, S Toyoda, I Taguchi, R Sohma, KI Inoue, S Nishino, K Node, G Attizzani, H Bezerra, M Costa, D Simon, T Inoue
Int J Cardiol Heart Vasc, 2018-02-16;18(0):17-24.
Species: Human
Sample Types: Serum
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Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the TLR4/NF-?B signaling pathway in vivo and in vitro
Authors: B Liu, F Ding, D Hu, Y Zhou, C Long, L Shen, Y Zhang, D Zhang, G Wei
Stem Cell Res Ther, 2018-01-12;9(1):7.
Species: Human
Sample Types: Cell Culture Supernates
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Synovial inflammation plays a greater role in post-traumatic osteoarthritis compared to idiopathic osteoarthritis in the Hartley guinea pig knee
Authors: NP Thomas, WJ Wu, BC Fleming, F Wei, Q Chen, L Wei
BMC Musculoskelet Disord, 2017-12-29;18(1):556.
Species: Guinea Pig
Sample Types: Synovial Lavage Fluid
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Tadalafil, a long acting phosphodiesterase inhibitor, promotes bone marrow stem cell survival and their homing into ischemic myocardium for cardiac repair
Authors: I Elmadbouh, M Ashraf
Physiol Rep, 2017-11-01;5(21):.
Species: Human
Sample Types: Cell Lysates
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Biological Features of Bone Marrow Mesenchymal Stromal Cells in Childhood Acute Lymphoblastic Leukemia
Authors: S Genitsari, E Stiakaki, C Perdikogia, G Martimiana, I Pelagiadis, M Pesmatzogl, M Kalmanti, H Dimitriou
Turk J Haematol, 2017-09-08;35(1):19-26.
Species: Human
Sample Types: Cell Culture Supernates
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Angiogenic T cell expansion correlates with severity of peripheral vascular damage in systemic sclerosis
Authors: M Manetti, S Pratesi, E Romano, S Bellando-R, I Rosa, S Guiducci, BS Fioretto, L Ibba-Manne, E Maggi, M Matucci-Ce
PLoS ONE, 2017-08-10;12(8):e0183102.
Species: Human
Sample Types: Serum
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Chemokine signals are crucial for enhanced homing and differentiation of circulating osteoclast progenitor cells
Authors: A Sucur, Z Jajic, M Artukovic, MI Matijasevi, B Anic, D Flegar, A Markotic, T Kelava, S Ivcevic, N Kovacic, V Katavic, D Grcevic
Arthritis Res. Ther., 2017-06-15;19(1):142.
Species: Human
Sample Types: Plasma
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The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models
Authors: GL Gravina, A Mancini, A Colapietro, F Vitale, A Vetuschi, S Pompili, G Rossi, F Marampon, PJ Richardson, L Patient, L Patient, S Burbidge, C Festuccia
Tumour Biol., 2017-06-01;39(6):1010428317695.
Species: Human
Sample Types: Cell Lysates
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Prostaglandin E2 promotes human CD34+ cells homing through EP2 and EP4 in�vitro
Authors: Y Wang, S Lai, J Tang, C Feng, F Liu, C Su, W Zou, H Chen, D Xu
Mol Med Rep, 2017-05-30;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Evaluation of autologous skeletal muscle-derived factors for regenerative medicine applications
Authors: M Yoshikawa, T Nakasa, M Ishikawa, N Adachi, M Ochi
Bone Joint Res, 2017-05-01;6(5):277-283.
Species: Human
Sample Types: Tissue Homogenates
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Differential expression of cell cycle and WNT pathway-related genes accounts for differences in the growth and differentiation potential of Wharton's jelly and bone marrow-derived mesenchymal stem cells
Authors: AK Batsali, C Pontikoglo, D Koutroulak, KI Pavlaki, A Damianaki, I Mavroudi, K Alpantaki, E Kouvidi, G Kontakis, HA Papadaki
Stem Cell Res Ther, 2017-04-26;8(1):102.
Species: Human
Sample Types: Cell Culture Supernates
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Alteration Analysis of Bone Marrow Mesenchymal Stromal Cells from De Novo Acute Myeloid Leukemia Patients at Diagnosis
Authors: L Desbourdes, J Javary, T Charbonnie, N Ishac, J Bourgeais, A Iltis, JC Chomel, A Turhan, F Guilloton, K Tarte, MV Demattei, E Ducrocq, F Rouleux-Bo, E Gyan, O Hérault, J Domenech
Stem Cells Dev., 2017-04-10;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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A novel recombinant antibody specific to full-length stromal derived factor-1 for potential application in biomarker studies
Authors: DI Bromage, S Taferner, M Pillai, DM Yellon, SM Davidson
PLoS ONE, 2017-04-05;12(4):e0174447.
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Vildagliptin, but not glibenclamide, increases circulating endothelial progenitor cell number: a 12-month randomized controlled trial in patients with type 2 diabetes
Authors: A Dei Cas, V Spigoni, M Cito, R Aldigeri, V Ridolfi, E Marchesi, M Marina, E Derlindati, R Aloe, RC Bonadonna, I Zavaroni
Cardiovasc Diabetol, 2017-02-23;16(1):27.
Species: Human
Sample Types: Plasma
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Human Lymph Node-Derived Fibroblastic and Double-Negative Reticular Cells Alter Their Chemokines and Cytokines Expression Profile Following Inflammatory Stimuli
Authors: P Severino, DT Palomino, H Alvarenga, CB Almeida, DC Pasqualim, A Cury, PR Salvalaggi, AL De Vasconc, MC Andrade, T Aloia, S Bromberg, LV Rizzo, FA Rocha, LC Marti
Front Immunol, 2017-02-14;8(0):141.
Species: Human
Sample Types: Cell Culture Supernates
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BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells
Authors: CD Graham, N Kaza, HC Pruitt, LM Gibson, BJ Klocke, LA Shevde, SL Carroll, KA Roth
Oncotarget, 2017-01-31;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Beneficial Effects of Reconstituted High-Density Lipoprotein (rHDL) on Circulating CD34+ Cells in Patients after an Acute Coronary Syndrome
Authors: C Gebhard, E Rh‚aume, C Berry, G Brand, AE Kernalegue, G Th‚berge-J, MA Alam, CY Lee, L Boileau, M Chabot-Bla, MC Guertin, MA Lavoie, J Gr‚goire, R Ibrahim, P L'Allier, JC Tardif
PLoS ONE, 2017-01-06;12(1):e0168448.
Species: Human
Sample Types: Serum
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The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma
Authors: GL Gravina, A Mancini, F Marampon, A Colapietro, S Delle Mona, R Sferra, F Vitale, PJ Richardson, L Patient, S Burbidge, C Festuccia
J Hematol Oncol, 2017-01-05;10(1):5.
Species: Human, Mouse
Sample Types: Cell Culture Supernates, Plasma
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Impact of Hyperglycemia and Low Oxygen Tension on Adipose-Derived Stem Cells Compared with Dermal Fibroblasts and Keratinocytes: Importance for Wound Healing in Type 2 Diabetes
PLoS ONE, 2016-12-19;11(12):e0168058.
Species: Human
Sample Types: Cell Culture Supernates
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Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells
Proc. Natl. Acad. Sci. U.S.A, 2016-12-16;0(0):.
Species: Human
Sample Types: Cell Lysates
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Kinetics of circulating endothelial progenitor cells in patients undergoing carotid artery surgery
Authors: Günay Kalender
Ther Clin Risk Manag, 2016-12-14;12(0):1841-1847.
Species: Human
Sample Types: Plasma
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Ligand-activated PPAR? downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression
Authors: D Rovito, G Gionfriddo, I Barone, C Giordano, F Grande, F De Amicis, M Lanzino, S Catalano, S Andò, D Bonofiglio
Oncotarget, 2016-10-04;7(40):65109-65124.
Species: Human
Sample Types: Cell Culture Supernates
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Innovative Flow Cytometry Allows Accurate Identification of Rare Circulating Cells Involved in Endothelial Dysfunction
PLoS ONE, 2016-08-25;11(8):e0160153.
Species: Human
Sample Types: Plasma
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Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling
Sci Rep, 2016-07-04;6(0):29029.
Species: Human
Sample Types: Cell Culture Supernates
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High throughput chemical library screening identifies a novel p110-? inhibitor that potentiates the anti-myeloma effect of bortezomib
Oncotarget, 2016-06-21;7(25):38523-38538.
Species: Human
Sample Types: Cell Culture Supernates
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Circulating Fibrocytes Are Increased in Neonates with Bronchopulmonary Dysplasia
Authors: Chun Li
PLoS ONE, 2016-06-16;11(6):e0157181.
Species: Human
Sample Types: Plasma
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Characterizing the angiogenic activity of patients with single ventricle physiology and aortopulmonary collateral vessels
Authors: N Sandeep, Y Uchida, K Ratnayaka, R McCarter, S Hanumantha, A Bangoura, Z Zhao, J Oliver-Dan, L Leatherbur, J Kanter, YS Mukouyama
J. Thorac. Cardiovasc. Surg., 2015-10-09;151(4):1126-35.e2.
Species: Human
Sample Types: Plasma
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EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance.
Authors: Nguyen T, Arthur A, Panagopoulos R, Paton S, Hayball J, Zannettino A, Purton L, Matsuo K, Gronthos S
Stem Cells, 2015-06-23;33(9):2838-49.
Species: Human
Sample Types: Cell Culture Supernates
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Chronic hyperglycemia induces trans-differentiation of human pancreatic stellate cells and enhances the malignant molecular communication with human pancreatic cancer cells.
Authors: Kiss K, Baghy K, Spisak S, Szanyi S, Tulassay Z, Zalatnai A, Lohr J, Jesenofsky R, Kovalszky I, Firneisz G
PLoS ONE, 2015-05-26;10(5):e0128059.
Species: Human
Sample Types: Cell Culture Supernates
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Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression.
Authors: Fullar A, Dudas J, Olah L, Hollosi P, Papp Z, Sobel G, Karaszi K, Paku S, Baghy K, Kovalszky I
BMC Cancer, 2015-04-11;15(0):256.
Species: Human
Sample Types: Cell Culture Supernates
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Elevated plasma CXCL12alpha is associated with a poorer prognosis in pulmonary arterial hypertension.
Authors: McCullagh B, Costello C, Li L, O'Connell C, Codd M, Lawrie A, Morton A, Kiely D, Condliffe R, Elliot C, McLoughlin P, Gaine S
PLoS ONE, 2015-04-09;10(4):e0123709.
Species: Human
Sample Types: Plasma
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Improved tumor vascularization after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in lung cancer.
Authors: Heist, Rebecca, Duda, Dan G, Sahani, Dushyant, Ancukiewicz, Marek, Fidias, Panos, Sequist, Lecia V, Temel, Jennifer, Shaw, Alice T, Pennell, Nathan A, Neal, Joel W, Gandhi, Leena, Lynch, Thomas J, Engelman, Jeffrey, Jain, Rakesh K
Proc Natl Acad Sci U S A, 2015-01-20;112(5):1547-52.
Species: Human
Sample Types: Plasma
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Plasma stromal cell-derived factor 1alpha/CXCL12 level predicts long-term adverse cardiovascular outcomes in patients with coronary artery disease.
Authors: Ghasemzadeh N, Hritani A, De Staercke C, Eapen D, Veledar E, Al Kassem H, Khayata M, Zafari A, Sperling L, Hooper C, Vaccarino V, Mavromatis K, Quyyumi A
Atherosclerosis, 2014-10-29;238(1):113-8.
Species: Human
Sample Types: Plasma
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SDF-1alpha is a novel autocrine activator of platelets operating through its receptor CXCR4.
Authors: Walsh T, Harper M, Poole A
Cell Signal, 2014-10-05;27(1):37-46.
Species: Human
Sample Types: Cell Culture Supernates
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Oxygen regulates human cytotrophoblast migration by controlling chemokine and receptor expression.
Authors: Schanz A, Red-Horse K, Hess A, Baston-Bust D, Heiss C, Krussel J
Placenta, 2014-09-26;35(12):1089-94.
Species: Human
Sample Types: Cell Culture Supernates
-
Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking.
Authors: Martin-Antonio B, Najjar A, Robinson S, Chew C, Li S, Yvon E, Thomas M, Mc Niece I, Orlowski R, Munoz-Pinedo C, Bueno C, Menendez P, Fernandez de Larrea C, Urbano-Ispizua A, Shpall E, Shah N
Cell Death Differ, 2014-08-29;22(1):96-107.
Species: Human
Sample Types: Cell Culture Supernates
-
Effects of pitavastatin versus atorvastatin on the peripheral endothelial progenitor cells and vascular endothelial growth factor in high-risk patients: a pilot prospective, double-blind, randomized study.
Authors: Lin L, Huang C, Chen J, Wu T, Leu H, Huang P, Chang T, Lin S, Chen J
Cardiovasc Diabetol, 2014-07-16;13(0):111.
Species: Human
Sample Types: Serum
-
Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy.
Authors: Zhang Y, Chen H, Sun C, Wang H, Liu M, Li Y, Nie X, Du M, Li D, Zhang J
PLoS ONE, 2014-06-16;9(6):e99612.
Species: Human
Sample Types: Cell Culture Supernates
-
Prostate stromal cells express the progesterone receptor to control cancer cell mobility.
Authors: Yu, Yue, Lee, Jennifer, Xie, Ning, Li, Estelle, Hurtado-Coll, Antonio, Fazli, Ladan, Cox, Michael, Plymate, Stephen, Gleave, Martin, Dong, Xuesen
PLoS ONE, 2014-03-24;9(3):e92714.
Species: Human
Sample Types: Cell Culture Supernates
-
Surgical sutures filled with adipose-derived stem cells promote wound healing.
Authors: Reckhenrich A, Kirsch B, Wahl E, Schenck T, Rezaeian F, Harder Y, Foehr P, Machens H, Egana J
PLoS ONE, 2014-03-13;9(3):e91169.
Species: Human
Sample Types: Cell Culture Supernates
-
Expression of and transcript variants and in epithelial ovarian cancer.
Authors: Jaszczynska-Nowinka K, Rucinski M, Ziolkowska A, Markowska A, Malendowicz L
Oncol Lett, 2014-02-20;7(5):1618-1624.
Species: Human
Sample Types: Plasma
-
The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization.
Authors: Hoellenriegel J, Zboralski D, Maasch C, Rosin N, Wierda W, Keating M, Kruschinski A, Burger J
Blood, 2013-11-25;123(7):1032-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Altered features and increased chemosensitivity of human breast cancer cells mediated by adipose tissue-derived mesenchymal stromal cells.
Authors: Kucerova L, Skolekova S, Matuskova M, Bohac M, Kozovska Z
BMC Cancer, 2013-11-09;13(0):535.
Species: Human
Sample Types: Cell Culture Supernates
-
Mobilization of circulating endothelial progenitor cells correlates with the clinical course of hantavirus disease.
Authors: Krautkramer E, Grouls S, Hettwer D, Rafat N, Tonshoff B, Zeier M
J Virol, 2013-10-23;88(1):483-9.
Species: Human
Sample Types: Plasma
-
Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution profile.
Authors: Paiva B, Paino T, Sayagues J, Garayoa M, San-Segundo L, Martin M, Mota I, Sanchez M, Barcena P, Aires-Mejia I, Corchete L, Jimenez C, Garcia-Sanz R, Gutierrez N, Ocio E, Mateos M, Vidriales M, Orfao A, San Miguel J
Blood, 2013-09-26;122(22):3591-8.
Species: Human
Sample Types: Plasma
-
Intranasal delivery of mesenchymal stem cells significantly extends survival of irradiated mice with experimental brain tumors.
Authors: Balyasnikova I, Prasol M, Ferguson S, Han Y, Ahmed A, Gutova M, Tobias A, Mustafi D, Rincon E, Zhang L, Aboody K, Lesniak M
Mol Ther, 2013-09-03;22(1):140-8.
Species: Human
Sample Types: Cell Lysates
-
Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies.
Authors: Frassanito M, Rao L, Moschetta M, Ria R, di Marzo L, De Luisi A, Racanelli V, Catacchio I, Berardi S, Basile A, Menu E, Ruggieri S, Nico B, Ribatti D, Fumarulo R, Dammacco F, Vanderkerken K, Vacca A
2013-09-02;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Differences are evident within the CXCR4-CXCL12 axis between ethnically divergent South African populations.
Authors: Shalekoff S, Schramm D, Lassauniere R, Picton A, Tiemessen C
Cytokine, 2013-02-08;61(3):792-800.
Species: Human
Sample Types: Plasma
-
Study of the quantitative, functional, cytogenetic, and immunoregulatory properties of bone marrow mesenchymal stem cells in patients with B-cell chronic lymphocytic leukemia.
Authors: Pontikoglou C, Kastrinaki M, Klaus M, Kalpadakis C, Katonis P, Alpantaki K, Pangalis G, Papadaki H
Stem Cells Dev, 2013-02-01;22(9):1329-41.
Species: Human
Sample Types: Cell Culture Supernates
-
BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy.
Authors: Pranzatelli, Michael, Tate, Elizabet, McGee, Nathan R, Travelstead, Anna L, Colliver, Jerry A, Ness, Jayne M, Ransohoff, Richard
J Neuroinflammation, 2013-01-16;10(0):10.
Species: Human
Sample Types: Serum
-
BMP9 regulates endoglin-dependent chemokine responses in endothelial cells.
Authors: Young, Kira, Conley, Barbara, Romero, Diana, Tweedie, Eric, O'Neill, Christin, Pinz, Ilka, Brogan, Louise, Lindner, Volkhard, Liaw, Lucy, Vary, Calvin P
Blood, 2012-09-26;120(20):4263-73.
Species: Human
Sample Types: Cell Culture Supernates
-
Breast milk from Tanzanian women has divergent effects on cell-free and cell-associated HIV-1 infection in vitro.
Authors: Lyimo M, Mosi M, Housman M, Zain-Ul-Abideen M, Lee F, Howell A, Connor R
PLoS ONE, 2012-08-28;7(8):e43815.
Species: Human
Sample Types: Milk
-
Involvement of the CXCR7/CXCR4/CXCL12 axis in the malignant progression of human neuroblastoma.
Authors: Liberman J, Sartelet H, Flahaut M, Muhlethaler-Mottet A, Coulon A, Nyalendo C, Vassal G, Joseph J, Gross N
PLoS ONE, 2012-08-20;7(8):e43665.
Species: Human
Sample Types: Tissue Homogenates
-
Elevated cerebral spinal fluid cytokine levels in boys with cerebral adrenoleukodystrophy correlates with MRI severity.
Authors: Lund TC, Stadem PS, Panoskaltsis-Mortari A, Raymond G, Miller WP, Tolar J, Orchard PJ
PLoS ONE, 2012-02-16;7(2):e32218.
Species: Human
Sample Types: Serum
-
Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury.
Authors: Quesnel C, Piednoir P, Gelly J, Nardelli L, Garnier M, Lecon V, Lasocki S, Bouadma L, Philip I, Elbim C, Mentre F, Soler P, Crestani B, Dehoux M
Crit. Care Med., 2012-01-01;40(1):21-8.
Species: Human
Sample Types: BALF
-
A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment.
Authors: Kulbe H, Chakravarty P, Leinster DA, Charles KA, Kwong J, Thompson RG, Coward JI, Schioppa T, Robinson SC, Gallagher WM, Galletta L, Salako MA, Smyth JF, Hagemann T, Brennan DJ, Bowtell DD, Balkwill FR
Cancer Res., 2011-11-07;72(1):66-75.
Species: Human
Sample Types: Cell Culture Supernates
-
Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.
Authors: McGuire TR, Brusnahan SK, Bilek LD, Jackson JD, Kessinger MA, Berger AM, Garvin KL, O'Kane BJ, Tuljapurkar SR, Sharp JG
Obesity (Silver Spring), 2011-09-08;19(11):2130-6.
Species: Human
Sample Types: Plasma
-
Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study.
Authors: Dubois SG, Shusterman S, Ingle AM, Ahern CH, Reid JM, Wu B, Baruchel S, Glade-Bender J, Ivy P, Grier HE, Adamson PC, Blaney SM
Clin. Cancer Res., 2011-06-20;17(15):5113-22.
Species: Human
Sample Types: Plasma
-
Levels of circulating CD45(dim)CD34(+)VEGFR2(+) progenitor cells correlate with outcome in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors.
Authors: Farace F, Gross-Goupil M, Tournay E, Taylor M, Vimond N, Jacques N, Billiot F, Mauguen A, Hill C, Escudier B
Br. J. Cancer, 2011-03-08;104(7):1144-50.
Species: Human
Sample Types: Plasma
-
Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities.
Authors: Farha S, Asosingh K, Xu W, Sharp J, George D, Comhair S, Park M, Tang WH, Loyd JE, Theil K, Tubbs R, Hsi E, Lichtin A, Erzurum SC
Blood, 2011-01-21;117(13):3485-93.
Species: Human
Sample Types: Plasma
-
Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment.
Authors: Otsuka H, Arimura N, Sonoda S
Am. J. Pathol., 2010-10-01;177(5):2268-77.
Species: Human
Sample Types: Vitreous Humor
-
Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair.
Authors: Li TS, Cheng K, Malliaras K, Matsushita N, Sun B, Marban L, Zhang Y, Marban E
Cardiovasc. Res., 2010-07-29;89(1):157-65.
Species: Human
Sample Types: Cell Culture Supernates
-
Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells.
Authors: Tso GH, Law HK, Tu W
Stem Cells, 2010-05-01;28(5):939-54.
Species: Human
Sample Types: Cell Culture Supernates
-
Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex.
Authors: Ratajczak MZ, Lee H, Wysoczynski M, Wan W, Marlicz W, Laughlin MJ, Kucia M, Janowska-Wieczorek A, Ratajczak J
Leukemia, 2010-04-01;24(5):976-85.
Species: Human
Sample Types: Plasma
-
Differential effect of ischaemic preconditioning on mobilisation and recruitment of haematopoietic and mesenchymal stem cells in porcine myocardial ischaemia-reperfusion.
Authors: Gyongyosi M, Posa A, Pavo N, Hemetsberger R, Kvakan H, Steiner-Boker S, Petrasi Z, Manczur F, Pavo IJ, Edes IF, Wojta J, Glogar D, Huber K
Thromb. Haemost., 2010-03-29;104(2):376-84.
Species: Human
Sample Types: Plasma
-
Distraction osteogenesis induces endothelial progenitor cell mobilization without inflammatory response in man.
Authors: Lee DY, Cho TJ, Lee HR, Park MS, Yoo WJ, Chung CY, Choi IH
Bone, 2009-10-22;46(3):673-9.
Species: Human
Sample Types: Plasma
-
Nodal lymphangiogenesis and metastasis: Role of tumor-induced lymphatic vessel activation in extramammary Paget's disease.
Authors: Hirakawa S, Detmar M, Kerjaschki D, Nagamatsu S, Matsuo K, Tanemura A, Kamata N, Higashikawa K, Okazaki H, Kameda K, Nishida-Fukuda H, Mori H, Hanakawa Y, Sayama K, Shirakata Y, Tohyama M, Tokumaru S, Katayama I, Hashimoto K
Am. J. Pathol., 2009-10-08;175(5):2235-48.
Species: Human
Sample Types: Cell Culture Supernates
-
Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target.
Authors: Chauhan D, Singh AV, Brahmandam M, Carrasco R, Bandi M, Hideshima T, Bianchi G, Podar K, Tai YT, Mitsiades C, Raje N, Jaye DL, Kumar SK, Richardson P, Munshi N, Anderson KC
Cancer Cell, 2009-10-06;16(4):309-23.
Species: Human
Sample Types: Cell Culture Supernates
-
Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9.
Authors: Kenig S, Alonso MB, Mueller MM, Lah TT
Cancer Lett., 2009-08-22;289(1):53-61.
Species: Human
Sample Types: Cell Culture Supernates
-
Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention.
Authors: Franciszkiewicz K, Le Floc'h A, Jalil A, Vigant F, Robert T, Vergnon I, Mackiewicz A, Benihoud K, Validire P, Chouaib S, Combadiere C, Mami-Chouaib F
Cancer Res., 2009-07-28;69(15):6249-55.
Species: Human
Sample Types: Cell Culture Supernates
-
The imbalance in serum concentration of Th-1- and Th-2-derived chemokines as one of the factors involved in pathogenesis of atopic dermatitis.
Authors: Narbutt J, Lesiak A, Sysa-Jedrzeiowska A, Zakrzewski M, Bogaczewicz J, Stelmach I, Kuna P
Mediators Inflamm., 2009-07-22;2009(0):269541.
Species: Human
Sample Types: Serum
-
Targeted disruption of the CXCL12/CXCR4 axis inhibits osteolysis in a murine model of myeloma-associated bone loss.
Authors: Diamond P, Labrinidis A, Martin SK, Farrugia AN, Gronthos S, To LB, Fujii N, O'Loughlin PD, Evdokiou A, Zannettino AC
J. Bone Miner. Res., 2009-07-01;24(7):1150-61.
Species: Human
Sample Types: Plasma
-
Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study.
Authors: Zhu AX, Sahani DV, Duda DG, di Tomaso E, Ancukiewicz M, Catalano OA, Sindhwani V, Blaszkowsky LS, Yoon SS, Lahdenranta J, Bhargava P, Meyerhardt J, Clark JW, Kwak EL, Hezel AF, Miksad R, Abrams TA, Enzinger PC, Fuchs CS, Ryan DP, Jain RK
J. Clin. Oncol., 2009-05-26;27(18):3027-35.
Species: Human
Sample Types: Plasma
-
Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs.
Authors: Makam M, Diaz D, Laval J, Gernez Y, Conrad CK, Dunn CE, Davies ZA, Moss RB, Herzenberg LA, Herzenberg LA, Tirouvanziam R
Proc. Natl. Acad. Sci. U.S.A., 2009-03-17;106(14):5779-83.
Species: Human
Sample Types: Plasma
-
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
Authors: Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
J. Immunol., 2008-12-01;181(11):8053-67.
Species: Human
Sample Types: BALF
-
Dysregulation of stromal derived factor 1/CXCR4 axis in the megakaryocytic lineage in essential thrombocythemia.
Authors: Salim JP, Goette NP, Lev PR, Chazarreta CD, Heller PG, Alvarez C, Molinas FC, Marta RF
Br. J. Haematol., 2008-11-01;144(1):69-77.
Species: Human
Sample Types: Plasma
-
Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents.
Authors: Shaked Y, Henke E, Roodhart JM, Mancuso P, Langenberg MH, Colleoni M, Daenen LG, Man S, Xu P, Emmenegger U, Tang T, Zhu Z, Witte L, Strieter RM, Bertolini F, Voest EE, Benezra R, Kerbel RS
Cancer Cell, 2008-09-09;14(3):263-73.
Species: Human
Sample Types: Plasma
-
Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
Exp. Hematol., 2008-05-27;36(8):1035-46.
Species: Human
Sample Types: Cell Culture Supernates
-
Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors.
Authors: Mahller YY, Vaikunth SS, Ripberger MC, Baird WH, Saeki Y, Cancelas JA, Crombleholme TM, Cripe TP
Cancer Res., 2008-02-15;68(4):1170-9.
Species: Human
Sample Types: Plasma
-
Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose.
Authors: Harrison ML, Obermueller E, Maisey NR, Hoare S, Edmonds K, Li NF, Chao D, Hall K, Lee C, Timotheadou E, Charles K, Ahern R, King DM, Eisen T, Corringham R, DeWitte M, Balkwill F, Gore M
J. Clin. Oncol., 2007-10-10;25(29):4542-9.
Species: Human
Sample Types: Plasma
-
Tissue engineering for full-thickness burns: a dermal substitute from bench to bedside.
Authors: Kellouche S, Martin C, Korb G, Rezzonico R, Bouard D, Benbunan M, Dubertret L, Soler C, Legrand C, Dosquet C
Biochem. Biophys. Res. Commun., 2007-09-04;363(3):472-8.
Species: Human
Sample Types: Cell Culture Supernates
-
Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells.
Authors: Irhimeh MR, Fitton JH, Lowenthal RM
Exp. Hematol., 2007-06-01;35(6):989-94.
Species: Human
Sample Types: Platelet Poor Plasma
-
Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium.
Authors: Ao M, Franco OE, Park D, Raman D, Williams K, Hayward SW
Cancer Res., 2007-05-01;67(9):4244-53.
Species: Human
Sample Types: Cell Culture Supernates
-
Serum levels of syndecan-1 in B-cell chronic lymphocytic leukemia: correlation with the extent of angiogenesis and disease-progression risk in early disease.
Authors: Molica S, Vitelli G, Mirabelli R, Digiesu G, Giannarelli D, Cuneo A, Ribatti D, Vacca A
Leuk. Lymphoma, 2006-06-01;47(6):1034-40.
Species: Human
Sample Types: Serum
-
Importance of recruitment of bone marrow-derived CXCR4+ cells in post-infarct cardiac repair mediated by G-CSF.
Authors: Misao Y, Takemura G, Arai M, Ohno T, Onogi H, Takahashi T, Minatoguchi S, Fujiwara T, Fujiwara H
Cardiovasc. Res., 2006-05-09;71(3):455-65.
Species: Rabbit
Sample Types: Serum
-
Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer.
Authors: Yasumoto K, Koizumi K, Kawashima A, Saitoh Y, Arita Y, Shinohara K, Minami T, Nakayama T, Sakurai H, Takahashi Y, Yoshie O, Saiki I
Cancer Res., 2006-02-15;66(4):2181-7.
Species: Human
Sample Types: Ascites Fluid
-
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
J. Immunol., 2005-11-01;175(9):6177-89.
Species: Human
Sample Types: Cell Culture Supernates
-
Recruitment of osteoclast precursors by stromal cell derived factor-1 (SDF-1) in giant cell tumor of bone.
Authors: Liao TS, Yurgelun MB, Chang SS, Zhang HZ, Murakami K, Blaine TA, Parisien MV, Kim W, Winchester RJ, Lee FY
J. Orthop. Res., 2005-01-01;23(1):203-9.
Species: Human
Sample Types: Cell Culture Supernates
-
SDF-1 is both necessary and sufficient to promote proliferative retinopathy.
Authors: Butler JM, Guthrie SM, Koc M, Afzal A, Caballero S, Brooks HL, Mames RN, Segal MS, Grant MB, Scott EW
J. Clin. Invest., 2005-01-01;115(1):86-93.
Species: Human
Sample Types: Vitreous Humor
-
Vitreous levels of vascular endothelial growth factor and stromal-derived factor 1 in patients with diabetic retinopathy and cystoid macular edema before and after intraocular injection of triamcinolone.
Authors: Brooks HL, Caballero S, Newell CK, Steinmetz RL, Watson D, Segal MS, Harrison JK, Scott EW, Grant MB
Arch. Ophthalmol., 2004-12-01;122(12):1801-7.
Species: Human
Sample Types: Vitreous Humor
-
Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction.
Authors: Massa M, Rosti V, Ferrario M, Campanelli R, Ramajoli I, Rosso R, De Ferrari GM, Ferlini M, Goffredo L, Bertoletti A, Klersy C, Pecci A, Moratti R, Tavazzi L
Blood, 2004-09-02;105(1):199-206.
Species: Human
Sample Types: Plasma
-
Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.
Authors: Casazza S, Zappia E, Pistorio A, Gambini C
Proc. Natl. Acad. Sci. U.S.A., 2004-07-19;101(30):11064-9.
Species: Human
Sample Types: CSF
-
Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2.
Authors: Metelitsa LS, Wu HW, Wang H, Yang Y, Warsi Z, Asgharzadeh S, Groshen S, Wilson SB, Seeger RC
J. Exp. Med., 2004-05-03;199(9):1213-21.
Species: Human
Sample Types: Cell Culture Supernates
-
Involvement of the CXCL12/CXCR4 pathway in the advanced liver disease that is associated with hepatitis C virus or hepatitis B virus.
Authors: Wald O, Pappo O, Safadi R, Dagan-Berger M, Beider K, Wald H, Franitza S, Weiss I, Avniel S, Boaz P, Hanna J, Zamir G, Eid A, Mandelboim O, Spengler U, Galun E, Peled A
Eur. J. Immunol., 2004-04-01;34(4):1164-74.
Species: Human
Sample Types: Plasma
-
Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
Authors: Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A
J. Leukoc. Biol., 2003-05-01;73(5):584-90.
Species: Human
Sample Types: CSF
-
Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice.
Authors: Cashman J, Clark-Lewis I, Eaves A, Eaves C
Blood, 2002-02-01;99(3):792-9.
Species: Human
Sample Types: Cell Culture Supernates
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Could detect in plasma at 10-fold and detectable in some urine samples at low concentration at 2-fold. No detected urine matrix effect