A 71915
Purity: ≥95%
Biological Activity
A 71915 is a highly potent and competitive natriuretic peptide receptor A (NPRA) antagonist (pKi = 9.18). Reduces brain natriuretic peptide (BNP, Cat. No. 3522)-induced scratching in mice.Technical Data
(Modifications: X-3 = Cha, X-11= D-Tic, Cys-13 = C-terminal amide, Disulfide bridge: 2-13)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Discovery of a potent atrial natriuretic peptide antagonist for ANPA receptors in the human neuroblastoma NB-OK-1 cell line.
Delporte et al.
Eur.J.Pharmacol., 1992;224:183 -
Functional and pharmacological characterization of the natriuretic peptide-dependent lipolytic pathway in human fat cells.
Moro et al.
J.Pharmacol.Exp.Ther., 2004;308:984 -
Spinal functions of B-type natriuretic peptide, gastrin-releasing peptide, and their cognate receptors for regulating itch in mice.
Kiguchi et al.
J.Pharmacol.Exp.Ther., 2016;356:596
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for A 71915
The citations listed below are publications that use Tocris products. Selected citations for A 71915 include:
1 Citation: Showing 1 - 1
-
Atrial Natriuretic Peptide and the Epithelial Sodium Channel Contribute to Spinal Cord Injury-Induced Polyuria in Mice.
Authors: Hui Et al.
J Neurotrauma 2022;39:724-734
FAQs
No product specific FAQs exist for this product, however you may
View all Peptide FAQsReviews for A 71915
There are currently no reviews for this product. Be the first to review A 71915 and earn rewards!
Have you used A 71915?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
