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BMS 605541

Catalog #: 6069 Datasheet / COA / SDS

Discontinued Product

6069 has been discontinued.
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BMS 605541 | CAS No. 639858-32-5 | VEGF Receptor Inhibitors
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Description: Potent VEGFR-2 inhibitor

Chemical Name: N-Cyclopropyl-2,4-difluoro-5-[[[2-(2-pyridinylamino)-5-thiazolyl]methyl]amino]benzamide

Purity: ≥98%

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Biological Activity

BMS 605541 is a potent ATP-competitive VEGFR-2 inhibitor (IC50 = 23 nM). Shows >10-fold selectivity for VEGFR-2 over VEGFR-1. Displays antitumor properties in human lung and colon tumor xenograft models. Orally bioavailable in rodents.

Technical Data

M.Wt:
401.43
Formula:
C19H17F2N5OS
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
639858-32-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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