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Potent FGFR and VEGFR inhibitor
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
Potent, selective inhibitor of VEGFR-2
Potent VEGFR, PDGFR and FGFR inhibitor
Potent, selective VEGFR-2 inhibitor
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
Neuropilin 1 (NRP1) receptor antagonist; inhibits VEGFA binding to NRP1
Potent VEGFR, PDGFRβ and KIT inhibitor
Potent multi-kinase and pan-Bcr-Abl inhibitor
Potent VEGFR-1, -2 and -3 inhibitor
Potent EGFR and VEGFR inhibitor
Potent VEGFR inhibitor; also inhibits other RTKs
Potent VEGFR inhibitor; also aromatase inhibitor
Potent inhibitor of VEGFR, PDGFR and FGFR
Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity