DC-Cholesterol hydrochloride
Tocris Bioscience | Catalog # 7176
Product Description
DC-Cholesterol hydrochloride is a cationic cholesterol derivative for use as a liposomal transfection reagent. Combines with the 'helper lipid' DOPE (Cat. No. 7175) after sonication or microfluidization to form unilamellar liposomes. Can be used in vitro and in vivo for transfer of nucleic acids, protein complexes, or other small molecule complexes into tissues, tumors and cells.
Product Specifications for DC-Cholesterol hydrochloride
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 2.69 | 5 with sonication | |
| Ethanol | 10.75 | 20 |
Preparing Stock Solutions for DC-Cholesterol hydrochloride
The following data is based on the product molecular weight 537.27.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 9.31 mL | 46.53 mL | 93.06 mL |
| 1 mM | 1.86 mL | 9.31 mL | 18.61 mL |
| 2 mM | 0.93 mL | 4.65 mL | 9.31 mL |
| 10 mM | 0.19 mL | 0.93 mL | 1.86 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Li DC-Chol lipid system in gene transfer. J.Control.Release
Product Documents for DC-Cholesterol hydrochloride
Product Specific Notices for DC-Cholesterol hydrochloride
For research use only
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