DL-AP4
Chemical Name: DL-2-Amino-4-phosphonobutyric acid
Purity: ≥98%
Biological Activity
DL-AP4 is a broad spectrum EAA ligand.D-isomer, L-isomer and Sodium Salt also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog.
Evans et al.
Br.J.Pharmacol., 1979;67:591 -
The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations.
Evans et al.
Br.J.Pharmacol., 1982;75:65
Product Datasheets
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Citations for DL-AP4
The citations listed below are publications that use Tocris products. Selected citations for DL-AP4 include:
6 Citations: Showing 1 - 6
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Design and validation of a foldable and photovoltaic wide-field epiretinal prosthesis.
Authors: Ferlauto Et al.
Nat Commun 2018;9:992
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Grk1b and Grk7a Both Contribute to the Recovery of the Isolated Cone Photoresponse in Larval Zebrafish.
Authors: Chrispell Et al.
Invest Ophthalmol Vis Sci 2018;59:5116
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A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease.
Authors: Vinberg Et al.
Hum Mol Genet 2015;24:5915
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Structure and function of bistratified intrinsically photosensitive retinal ganglion cells in the mouse.
Authors: Schmidt and Kofuji
J Comp Neurol 2011;519:1492
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Functional and morphological differences among intrinsically photosensitive retinal ganglion cells.
Authors: Schmidt and Kofuji
J Neurosci 2009;29:476
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Melanopsin-dependent photoreception provides earliest light detection in the mammalian retina.
Authors: Sekaran Et al.
Curr Biol 2005;15:1099
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