Human CD300e/LMIR6 Antibody

Catalog # Availability Size / Price Qty
AF2705
AF2705-SP
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Human CD300e/LMIR6 Antibody Summary

Species Reactivity
Human
Specificity
Detects human CD300e/LMIR6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross‑reactivity with recombinant human LMIR1, 2, 3, 4, and 5 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CD300e/LMIR6
Gly20-Leu169
Accession # BAG60333
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human CD300e/LMIR6

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CD300e/LMIR6

LMIR6, also known as immune receptor expressed by myeloid cell 2 (IREM-2) and CD300 antigen-like family member E (CD300e), is a type I transmembrane protein that has an extracellular domain containing an Ig-like domain and a transmembrane domain with a positive charge. It is predicted to be an activating receptor that associates with ITAM motif-containing adaptor proteins. LMIR6/IREM-2 is expressed on mature hematopoietic cells of the monocytic and myeloid dendritic cell lineages.

Entrez Gene IDs
342510 (Human); 217306 (Mouse)
Alternate Names
CD300 antigen like family member E; CD300 antigen-like family member E; CD300e antigenPIgR-2; CD300e molecule; CD300e; CD300LE; CD300LEPIgR2; CLM2; CLM-2; CLM2CMRF35-A5; CMRF35A5; CMRF35-like molecule 2; Immune receptor expressed on myeloid cells 2; IREM-2; IREM2IREM-2; LMIR6; Poly-Ig receptor 2; Polymeric immunoglobulin receptor 2

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