Human CREG Biotinylated Antibody

Catalog #: BAF2380 Datasheet / COA / SDS

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BAF2380

All CREG Antibodies

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Human CREG Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human CREG in Western blots. In Western blots, approximately 50% cross-reactivity with recombinant mouse CREG is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CREG
Arg32-Gln220
Accession # O75629

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human CREG

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CREG

CREG is a secreted glycoprotein that belongs to the CREG protein family. It is induced during differentiation of pluripotent cells and is ubiquitously expressed in adult tissues. Mannose-6 phosphate (M6P) modified CREG binds directly to the M6P/IGF2 receptor to inhibit cell growth (1). Human and mouse CREG share approximately 77% amino acid sequence homology.

Long Name

Cellular Repressor of E1A-stimulated Genes

Entrez Gene IDs

8804 (Human); 433375 (Mouse)

Alternate Names

cellular repressor of E1A-stimulated genes 1CREG; cellular repressor of E1A-stimulated genes; CREG; CREG1; protein CREG1