Human ICAM-2/CD102 Biotinylated Antibody

Catalog #: BAF244
1 Citation Datasheet / COA / SDS

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BAF244

All ICAM-2/CD102 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human ICAM-2/CD102 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human ICAM‑2/CD102 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human (rh) ICAM-1 and rhPECAM is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human ICAM‑2/CD102
Lys25-Gln223
Accession # CAA33630

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human ICAM‑2/CD102 Fc Chimera (Catalog # 803-I2)

Flow Cytometry

2.5 µg/10⁶ cells

Human peripheral blood monocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available

Reconstitution Buffer 1 (PBS)

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: ICAM-2/CD102

Intercellular Adhesion Molecule-2 (ICAM-2, CD102), a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM-2 is constitutively expressed at high levels on vascular endothelial cells and lymphohematopoietic cells. ICAM-2 mediated adhesion has been shown to provide a co-stimulatory signal for T cell aggregation, NK cytotoxicity and NK cell migration.

References

Somersalo, K. et al. (1995) J. Biol. Chem. 270:8629.
Hayflick, J. et al. (1998) Immunologic Res. 17:313.

Long Name

Intercellular Adhesion Molecule 2

Entrez Gene IDs

3384 (Human); 15896 (Mouse)

Alternate Names

CD102 antigen; CD102; ICAM2; ICAM-2; intercellular adhesion molecule 2

Product Datasheets

Product Datasheet

COA

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Related Research Areas

Citation for Human ICAM-2/CD102 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

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