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Human IL-2 Biotinylated Fluorokine Flow Cytometry Kit

Catalog #: NF200
5 Citations Datasheet / COA / SDS

Discontinued Product

NF200 has been discontinued.
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Citations (5)
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Human IL-2 Biotinylated Fluorokine Flow Cytometry Kit Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Species
Human

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Background: IL-2

IL-2 (Interleukin 2) is a critical cytokine in T cell biology. It promotes T cell activation and expansion, the development, maintenance and function of regulatory T cells (Treg), and the differentiation of CD8+ T cells into terminal effector cells and memory cells. IL-2 signals through a receptor complex composed of CD25/IL-2 R alpha, IL-2 R beta, and the Common gamma Chain (gamma c). IL-2 R beta is also a component of the IL-15 receptor complex. Gamma c is also a signaling subunit in the receptors for IL-4, -7, -9, -15, and -21.

Long Name
Interleukin 2
Entrez Gene IDs
3558 (Human); 16183 (Mouse); 116562 (Rat); 396868 (Porcine); 280822 (Bovine); 403989 (Canine); 100034204 (Equine); 751114 (Feline); 100302458 (Rabbit)
Alternate Names
Aldesleukin; IL2; IL-2; IL-2lymphokine; interleukin 2; interleukin-2; involved in regulation of T-cell clonal expansion; Proleukin; T cell growth factor; T-cell growth factor; TCGF

Citations for Human IL-2 Biotinylated Fluorokine Flow Cytometry Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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  1. ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut
    Authors: M Lyu, H Suzuki, L Kang, F Gaspal, W Zhou, J Goc, L Zhou, J Zhou, W Zhang, JRI Live C, Z Shen, JG Fox, RE Sockolow, TM Laufer, Y Fan, G Eberl, DR Withers, GF Sonnenberg
    Nature, 2022-09-07;0(0):.  2022-09-07
  2. Interleukin-7 optimizes FOXP3+CD4+ regulatory T cells reactivity to interleukin-2 by modulating CD25 expression.
    Authors: Simonetta F, Gestermann N, Bloquet S, Bourgeois C
    PLoS ONE, 2014-12-08;9(12):e113314.  2014-12-08
  3. The development of methods for immunophenotypic and lymphocyte function analyzes for assessment of Southern sea otter (Enhydra lutris nereis) health.
    Authors: Schwartz J, Aldridge B, Blanchard M, Mohr FC, Stott J
    Vet. Immunol. Immunopathol., 2005-03-10;104(1):1-14.  2005-03-10
  4. Functional interleukin-2 receptors are expressed on natural killer-like leukemic cells from a dog with cutaneous lymphoma.
    Authors: Helfand SC, Modiano JF, Moore PF, Soergel SA, MacWilliams PS, Dubielzig RD, Hank JA, Gelfand EW, Sondel PM
    Blood, 1995-07-15;86(2):636-45.  1995-07-15
  5. Chronic & infrequent opioid exposure suppresses IL-2R expression on rhesus monkey peripheral blood mononuclear cells following stimulation with pokeweed mitogen.
    Authors: Carr DJ, ºùN•iÓ)f½, Carpenter GW, i%Êv-Ž¦, Garza HH, France CP, Prakash OM
    1995-03-01;81(1):137-48.  1995-03-01

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