Human/Mouse Olig2 Biotinylated Antibody

Catalog #: BAF2418
4 Citations Datasheet / COA / SDS

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BAF2418

All Olig2 Antibodies

Product Details

Citations (4)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse Olig2 Biotinylated Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects Olig2 in Western blots. In Western blots, less than 5% cross-reactivity with recombinant human (rh) Olig1 and rhOlig3 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human Olig2
Met1-Lys323
Accession # Q13516

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human Olig2

Immunohistochemistry

5-15 µg/mL

Immersion fixed frozen sections of embryonic mouse spinal cord (E11)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Olig2

Olig1 and Olig2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the motor neuron progenitor (pMN) domain of the spinal cord that generates motor neurons and oligodendrocytes. Olig1 is involved in the development and maturation of oligodendrocytes. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord.

Long Name

Oligodendrocyte Lineage Transcription Factor 2

Entrez Gene IDs

10215 (Human)

Alternate Names

BHLHB1; BHLHE19; Class B basic helix-loop-helix protein 1; Class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; Olig2; OLIGO2; oligodendrocyte lineage transcription factor 2; oligodendrocyte transcription factor 2; oligodendrocyte-specific bHLH transcription factor 2; PRKCBP2; protein kinase C binding protein 2; Protein kinase C-binding protein 2; Protein kinase C-binding protein RACK17; RACK17; RACK17helix-loop-helix protein, class B, 1

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human/Mouse Olig2 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner
Authors: Mio Oshikawa, Kei Okada, Kazunori Nakajima, Itsuki Ajioka
Development
A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability
Authors: Emma V. Bird, Tommaso Iannitti, Claire R. Christmas, Ilona Obara, Veselin I. Andreev, Anne E. King et al.
Neuroscience
Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation
Authors: A Xu, M Liu, MF Huang, Y Zhang, R Hu, JA Gingold, Y Liu, D Zhu, CS Chien, WC Wang, Z Liao, F Yuan, CW Hsu, J Tu, Y Yu, T Rosen, F Xiong, P Jia, YP Yang, DA Bazer, YW Chen, W Li, CD Huff, JJ Zhu, F Aguilo, SH Chiou, NC Boles, CC Lai, MC Hung, Z Zhao, EL Van Nostra, R Zhao, DF Lee
Nature Communications, 2023-03-27;14(1):1694.
Species: Human
Sample Types: Whole Cells
Applications: ICC
Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development
Authors: M Komabayash, E Yamanishi, C Watanabe, M Okamura, H Tabata, R Iwai, I Ajioka, J Matsushita, H Kidoya, N Takakura, T Okamoto, K Kinoshita, M Ichihashi, KI Nagata, M Ema, KI Mizutani
Cell Rep, 2019-10-29;29(5):1113-1129.e5.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC