Human TSPAN1 (NP_005718) VersaClone cDNA

Catalog #: RDC0190 Datasheet / COA / SDS

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Human TSPAN1 (NP_005718) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: TSPAN1

TSPAN1 belongs to the large family of tetraspanins, so named because they contain 4 transmembrane domains. TSPAN1 is expressed in colon, endometrium, pancreas, normal and neoplastic prostate, and pregnant uterus. Tetraspanins are frequently expressed at the cell surface in association with each other and with other molecules, such as integrins, and they function to regulate cell adhesion, migration, proliferation, and differentiation. RNAi-mediated downregulation of TSPAN1 expression significantly inhibits the proliferation and invasion of colon cancer cells in vitro. This finding suggests that TSPAN1 plays an important role in colon cancer progression.

Long Name

Tetraspanin 1

Entrez Gene IDs

10103 (Human); 66805 (Mouse); 298436 (Rat)

Alternate Names

NET1; NET-1; tetraspan 1; Tetraspan NET-1; tetraspanin 1; Tetraspanin TM4-C; tetraspanin-1; TM4C; TM4SF; TSPAN1; TSPAN-1