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MNI-caged-NMDA

Catalog #: 2224
1 Citation Datasheet / COA / SDS

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2224 has been discontinued.
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MNI-caged-NMDA | CAS No. 1227675-52-6 | Additional NMDA Receptor Compounds
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Description: Caged NMDA
Alternative Names: 4-Methoxy-7-nitroindolinyl-caged N-methyl-D-aspartic acid

Chemical Name: (R)-α-Methylamino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

MNI-caged-NMDA is a NMDA (Cat.No. 0114) caged with the photosensitive 4-methoxy-7-nitroindolinyl group. Stoichiometrically releases chirally pure NMDA. Suitable for uncaging with 300-380 nm excitation. Improved localization can be achieved by uncaging at 405 nm (with mM concentration of caged compound in the bath solution). Exhibits rapid uncaging rate relative to ionotropic glutamate receptor activation.

Technical Data

M.Wt:
323.3
Formula:
C14H17N3O6
Solubility:
Soluble to 5 mM in water with gentle warming and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
1227675-52-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the UK Medical Research Council

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Citation for MNI-caged-NMDA

The citations listed below are publications that use Tocris products. Selected citations for MNI-caged-NMDA include:

1 Citation: Showing 1 - 1

  1. Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors.
    Authors: Zhang Et al.
    Nat.Commun.  2016;7:12650

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