Mouse CD200R1 (NP_067300) VersaClone cDNA

Catalog #: RDC2084 Datasheet / COA / SDS

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RDC2084

Mouse CD200R1 (NP_067300) VersaClone cDNA

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Mouse CD200R1 (NP_067300) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Mouse

Product Datasheets

Product Datasheet

COA

SDS

Background: CD200R1

CD200 antigen, also known as OX-2, is a type I transmembrane protein belonging to the Ig superfamily. It has a 202 amino acid extracellular domain and a short (19 aa) cytoplasmic tail. At least two alternate splice isoforms exist that differ in their cytoplasmic domains. CD200 is widely expressed in multiple cell types. It interacts with CD200 R1, another Ig superfamily inhibitory receptor primarily expressed on leukocytes of the myeloid lineage, to inhibit myeloid functions.

CD200 R1, also known as OX-2 receptor, is a transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed primarily in cells of the myeloid lineage, while its ligand, CD200, is widely distributed. CD200 R1 is though to propagate inhibitory signals and disruption of the CD200/CD200 R1 receptor-ligand pair leads to a predisposition to autoimmune phenotypes.

Long Name

CD200 Receptor 1

Entrez Gene IDs

131450 (Human); 57781 (Mouse); 102139962 (Cynomolgus Monkey)

Alternate Names

CD200 R1; CD200 receptor 1; CD200R1; CD200RMOX2Rcell surface glycoprotein CD200 receptor 1; Cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200; CRTR2; HCRTR2; MOX2 receptor; MOX2R; OX2RCD200 cell surface glycoprotein receptor