Eosinophils
Produced in the bone marrow, eosinophils differentiate from myeloid precursor cells in response to IL-3, IL-5 and GM-CSF. Eosinophils are polymorphonuclear leukocytes, characterized by eosinophilic granules in the cytoplasm. Eosinophils respond to chemokine attractants secreted by lymphocytes and neutrophils, such as CCL11/eotaxin-1, CCL24/eotaxin-2, and CCL5/RANTES. Recruited eosinophils release the toxic substances contained in their granules to destroy invasive entities and combat infection.
- alpha 1B-Glycoprotein
- B220/CD45R
- CCL5/RANTES
- CCL11/Eotaxin
- CCL24/Eotaxin-2/MPIF-2
- CCR3
- CD23/Fc epsilon RII
- CD43
- CD45
- CD69
- CD200R1
- CD200R1L
- CD45RA
- CD45RB
- CD45RO
- CRISP-3
- CRTH-2
- EMMPRIN/CD147
- EMR1
- F4/80
- Galectin-9
- Histamine H4R
- ICAM-2/CD102
- IL-5 R alpha/CD125
- IL-3R alpha
- IL-3R beta
- Integrin alpha 4/CD49d
- Integrin alpha 4 beta 1
- Integrin alpha 4 beta 7/LPAM-1
- Integrin beta 2/CD18
- Leukotriene B4 R1
- Leukotriene B4 R2
- LILRA4/CD85g/ILT7
- MBP-1
- PRG3/MBP2
- Siglec-8
- TRA-1-85/CD147
- YM1/Chitinase 3-like 3