Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit Summary
Sample Values
Serum/Plasma - Twenty samples were evaluated for the presence of mouse IL-1 beta in this assay. Serum samples measured as shown in the table below. All twenty plasma samples measured less than the lowest Mouse IL-1 beta Standard, 12.5 pg/mL.Sample Type | Mean of Detectable (pg/mL) | % Detectable | Range (pg/mL) |
Serum (n=20) | 27.6 | 10 | ND-37.9 |
Sample Type | Day 3 (pg/mL) | Day 6 (pg/mL) |
J774A.1 Unstimulated | ND | ND |
J774A.1 Stimulated with LPS + GM-CSF | 587 | 938 |
Tissue Lysate | (pg/mL) |
Brain | 20.9 |
Heart | 28.3 |
Kidney | 111 |
Liver | 347 |
Lung | 115 |
Spleen | 987 |
Product Summary
Precision
Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 20 | 20 | 20 |
Mean (pg/mL) | 33.5 | 92.9 | 386 | 34.6 | 93.5 | 423 |
Standard Deviation | 2.5 | 4.3 | 11.7 | 2.9 | 6.2 | 23.9 |
CV% | 7.5 | 4.6 | 3 | 8.4 | 6.6 | 5.7 |
Recovery
The recovery of mouse IL-1 beta spiked to three levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Supernates (n=4) | 106 | 95-119 |
EDTA Plasma (n=4) | 108 | 101-117 |
Heparin Plasma (n=4) | 97 | 87-114 |
Serum (n=4) | 105 | 98-113 |
Tissue Lysates (n=4) | 115 | 110-120 |
Linearity
Scientific Data
Human E‑Cadherin Antibody PYC suppressed LPS-induced proinflammatory cytokine production in BV2 microglia.Cells were incubated with the indicated concentrations of PYC or vehicle for 1h before LPS treatment (500ng/mL). After 24 h incubation, the culture supernatants were collected, and the amount of TNF-alpha, IL-6, IL-1 beta and IL-10 were measured by ELISA (A-D). Data are represented as mean ± SD from at least 3 independent experiments. *P< 0.05 compared with LPS alone. #P< 0.05. Image collected and cropped by CiteAb from the following open publication (https://dx.plos.org/10.1371/journal.pone.0137837), licensed under a CC-BY license. Not internally tested by R&D Systems.
Product Datasheets
Preparation and Storage
Background: IL-1 beta/IL-1F2
The Interleukin 1 (IL-1) family of proteins consists of IL-1 alpha, IL-1 beta, and the IL-1 receptor antagonist (IL-1ra). IL-1 alpha and IL-1 beta bind to the same cell surface receptors and share biological functions (1). IL-1 is not produced by unstimulated cells of healthy individuals with the exception of skin keratinocytes, some epithelial cells, and certain cells of the central nervous system. However, in response to inflammatory agents, infections, or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cell types is seen. IL-1 beta plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. Inappropriate or prolonged production of IL-1 has been implicated in a variety of pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulindependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases (2-5).
Citations for Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Akkermansia muciniphila alleviates abdominal aortic aneurysms via restoring CITED2 activated by EPAS1
Authors: Wang, S;Shi, H;Cheng, Y;Jiang, L;Lou, Y;Kumar, M;Sun, M;Shao, X;Zhao, X;Wang, B;
Infection and immunity
Species: Mouse
Sample Types: Cell Culture Supernates, Tissue Homogenates
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Macrophage WDFY3, a protector against autoimmunity
Authors: Wu, X;Wang, Z;Croce, KR;Li, F;Cui, J;D'Agati, VD;Soni, RK;Khalid, S;Saleheen, D;Tabas, I;Yamamoto, A;Zhang, H;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Cell Culture Supernates
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Huperzine a ameliorates sepsis-induced acute lung injury by suppressing inflammation and oxidative stress via ?7 nicotinic acetylcholine receptor
Authors: Su, J;Chen, K;Sang, X;Feng, Z;Zhou, F;Zhao, H;Wu, S;Deng, X;Lin, C;Lin, X;Xie, L;Ye, H;Chen, Q;
International immunopharmacology
Species: Mouse
Sample Types: Tissue Homogenates
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Combining Aloin with TIENAM ameliorates cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating abdominal cavity microbiota
Authors: Su, J;Xiao, J;Deng, X;Lin, X;Xie, L;Ye, H;Lin, C;Zhou, F;Wu, S;
International immunopharmacology
Species: Mouse
Sample Types: Serum, Tissue Homogenates
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DNA-sensing inflammasomes cause recurrent atherosclerotic stroke
Authors: Cao, J;Roth, S;Zhang, S;Kopczak, A;Mami, S;Asare, Y;Georgakis, MK;Messerer, D;Horn, A;Shemer, R;Jacqmarcq, C;Picot, A;Green, JP;Schlegl, C;Li, X;Tomas, L;Dutsch, A;Liman, TG;Endres, M;Wernsdorf, SR;Fürle, C;Carofiglio, O;Zhu, J;Brough, D;DEMDAS Study Group, ;Hornung, V;Dichgans, M;Vivien, D;Schulz, C;Dor, Y;Tiedt, S;Sager, HB;Grosse, GM;Liesz, A;
Nature
Species: Mouse
Sample Types: Tissue Homogenates
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Caspase-4/11 promotes hyperlipidemia and chronic kidney disease-accelerated vascular inflammation by enhancing trained immunity
Authors: Sun, Y;Lu, Y;Liu, L;Saaoud, F;Shao, Y;Xu, K;Drummer Iv, C;Cueto, R;Shan, H;Jiang, X;Zhao, H;Wang, H;Yang, X;
JCI insight
Species: Transgenic Mouse
Sample Types: Plasma
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In vivo magnetogenetics for cell-type-specific targeting and modulation of brain circuits
Authors: Choi, SH;Shin, J;Park, C;Lee, JU;Lee, J;Ambo, Y;Shin, W;Yu, R;Kim, JY;Lah, JD;Shin, D;Kim, G;Noh, K;Koh, W;Lee, CJ;Lee, JH;Kwak, M;Cheon, J;
Nature nanotechnology
Species: Transgenic Mouse
Sample Types: Tissue Homogenates
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Intraductal photothermal ablation: a noninvasive approach for early breast cancer treatment and prevention
Authors: Liu, J;Huang, B;Rao, Y;Guo, L;Cai, C;Gao, D;Kong, D;Wang, G;Xiong, Y;Cui, R;Zhang, M;Chen, C;
Theranostics
Species: Mouse
Sample Types: Tissue Homogenates
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Geranylgeranylacetone mitigates sepsis-associated intestinal injury through CHIP-dependent anti-inflammation and anti-oxidative effect
Authors: Liu, X;Liu, Y;Su, X;Jiang, L;Tang, G;Wang, Y;
International immunopharmacology
Species: Mouse
Sample Types: Tissue Homogenates
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Augmented antitumor immune responses of HER2-targeted pyroptotic induction by long-lasting recombinant immunopyroptotins
Authors: Xing, Y;Zhang, F;Yang, T;Yin, C;Yang, A;Yan, B;Zhao, J;
Heliyon
Species: Mouse
Sample Types: Plasma, Tissue Homogenates
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Insights into the effect of guanylate-binding protein 1 on the survival of Brucella intracellularly
Authors: Li, Z;Wang, S;Han, J;Yang, G;Xi, L;Zhang, C;Cui, Y;Yin, S;Zhang, Y;Zhang, H;
Veterinary microbiology
Species: Mouse
Sample Types: Cell Culture Supernates
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Mesenchymal stem cell-derived exosomes overexpressing SRC-3 protect mice from cerebral ischemia by inhibiting ferroptosis
Authors: Deng, M;Hou, Y;Liu, J;He, J;Lan, Z;Xiao, H;
Brain research bulletin
Species: Mouse
Sample Types: Cell Culture Supernates
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Oral TNF-? siRNA delivery via milk-derived exosomes for effective treatment of inflammatory bowel disease
Authors: Han, G;Kim, H;Jang, H;Kim, ES;Kim, SH;Yang, Y;
Bioactive materials
Species: Mouse
Sample Types: Bacteria
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Platelet-rich plasma-derived extracellular vesicles inhibit NF-?B/NLRP3 pathway-mediated pyroptosis in intervertebral disc degeneration via the MALAT1/microRNA-217/SIRT1 axis
Authors: Tao, X;Xue, F;Xu, J;Wang, W;
Cellular signalling
Species: Mouse
Sample Types:
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A Novel Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-Kappa B Activation Pathway is Involved in the Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemia-Reperfusion Lung Injury
Authors: Miyashita, Y;Kanou, T;Fukui, E;Matsui, T;Kimura, T;Ose, N;Funaki, S;Shintani, Y;
Transplantation proceedings
Species: Mouse
Sample Types: Plasma
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SELENOK-dependent CD36 palmitoylation regulates microglial functions and A? phagocytosis
Authors: Ouyang, P;Cai, Z;Peng, J;Lin, S;Chen, X;Chen, C;Feng, Z;Wang, L;Song, G;Zhang, Z;
Redox biology
Species: Mouse
Sample Types: Bacteria
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A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome
Authors: Song, J;Wu, J;Robichaux, DJ;Li, T;Wang, S;Arredondo Sancristobal, MJ;Dong, B;Dobrev, D;Karch, J;Thomas, SS;Li, N;
Cells
Species: Mouse
Sample Types: Serum
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RAGE in circulating immune cells is fundamental for hippocampal inflammation and cognitive decline in a mouse model of latent chronic inflammation
Authors: Ye, D;Miyoshi, A;Ushitani, T;Kadoya, M;Igeta, M;Konishi, K;Shoji, T;Yasuda, K;Kitaoka, S;Yagi, H;Kuroda, E;Yamamoto, Y;Cheng, J;Koyama, H;
Brain, behavior, and immunity
Species: Transgenic Mouse
Sample Types: Serum
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Enhancement of Immune Functions by Limosilactobacillus reuteri KBL346: In Vitro and In Vivo Studies
Authors: Park, C;Ji, SY;Hwangbo, H;Shin, SY;Kim, MY;Lee, K;Kim, DH;Cho, BR;Lee, H;Choi, YH;You, HJ;
International journal of molecular sciences
Species: Mouse
Sample Types: Serum
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Berberine Mediates the Production of Butyrate to Ameliorate Cerebral Ischemia via the Gut Microbiota in Mice
Authors: Duan, H;Hu, J;Deng, Y;Zou, J;Ding, W;Peng, Q;Duan, R;Sun, J;Zhu, J;
Nutrients
Species: Mouse
Sample Types: Tissue Homogenates
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The tetrapeptide sequence of IL-18 and IL-1? regulates their recruitment and activation by inflammatory caspases
Authors: Exconde, PM;Hernandez-Chavez, C;Bourne, CM;Richards, RM;Bray, MB;Lopez, JL;Srivastava, T;Egan, MS;Zhang, J;Yoo, W;Shin, S;Discher, BM;Taabazuing, CY;
Cell reports
Species: Mouse
Sample Types: Cell Culture Supernates
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Isobavachin, a main bioavailable compound in Psoralea corylifolia, alleviates lipopolysaccharide-induced inflammatory responses in macrophages and zebrafish by suppressing the MAPK and NF-?B signaling pathways
Authors: Chung, YC;Song, SJ;Lee, A;Jang, CH;Kim, CS;Hwang, YH;
Journal of ethnopharmacology
Species: Mouse
Sample Types: Cell Culture Supernates
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Arabinose confers protection against intestinal injury by improving integrity of intestinal mucosal barrier
Authors: Xu, M;Shi, F;Gao, Y;Han, S;Huang, C;Hou, Q;Wen, X;Wang, B;Zhu, Z;Zou, L;Xiong, M;Dong, W;Tan, J;
International immunopharmacology
Species: Mouse
Sample Types: Serum, Tissue Homogenates
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METTL3-mediated N6-methyladenosine modification stimulates mitochondrial damage and ferroptosis of kidney tubular epithelial cells following acute kidney injury by modulating the stabilization of MDM2-p53-LMNB1 axis
Authors: Hu, C;Zhang, B;Zhao, S;
European journal of medicinal chemistry
Species: Mouse
Sample Types: Serum, Tissue Homogenates
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Synthesis and characterization of piperic acid conjugates with homochiral and heterochiral dipeptides containing phenylalanine and their application in skin cancer
Authors: Ur Rahim, J;Faheem, MM;Nawaz, S;Goswami, A;Rai, R;
Peptides
Species: Mouse
Sample Types: Serum
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NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis
Authors: Chen, WC;Yu, WK;Su, VY;Hsu, HS;Yang, KY;
International journal of molecular sciences
Species: Mouse
Sample Types: Tissue Homogenates
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Hsp70 ameliorates sleep deprivation-induced anxiety-like behavior and cognitive impairment in mice
Authors: Kang, Z;Lin, Y;Su, C;Li, S;Xie, W;Wu, X;
Brain research bulletin
Species: Mouse
Sample Types: Tissue Homogenates
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Research of STEAP3 interaction with Rab7A and RACK1 to modulate the MAPK and JAK/STAT signaling in Osteoarthritis
Authors: Sun, C;Peng, S;Lv, Z;Guo, T;Zhang, L;
International immunopharmacology
Species: Rat
Sample Types: Cell Culture Supernates
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Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p
Authors: Wang, C;Feng, L;Zhu, L;Wu, L;Chen, B;Cui, C;Yang, M;Gao, Y;Jiang, P;
Cell death & disease
Species: Mouse
Sample Types: Extracellular Vesicles
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Mycobacterium tuberculosis carrying the rifampicin drug-resistance-conferring rpoB mutation H445Y is associated with suppressed immunity through type I interferons
Authors: Bobba, S;Howard, NC;Das, S;Ahmed, M;Tang, L;Thirunavukkarasu, S;Larsen, MH;Mathema, B;Divangahi, M;Khader, SA;
mBio
Species: Mouse
Sample Types: Cell Culture Supernates, Tissue Homogenates
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Fucoxanthin Ameliorates Sepsis via Modulating Microbiota by Targeting IRF3 Activation
Authors: Su, J;Guan, B;Su, Q;Hu, S;Wu, S;Tong, Z;Zhou, F;
International journal of molecular sciences
Species: Mouse
Sample Types: Tissue Homogenates
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Low‑dose ionizing radiation attenuates high glucose‑induced hepatic apoptosis and immune factor release via modulation of a miR‑155‑SOCS1 axis
Authors: Fan, H;Liu, S;Jiao, B;Liang, X;
Molecular medicine reports
Species: Mouse
Sample Types: Cell Culture Supernates
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Dihydroquercetin (DHQ) ameliorates LPS-induced acute lung injury by regulating macrophage M2 polarization through IRF4/miR-132-3p/FBXW7 axis
Authors: Li, C;Liu, J;Zhang, C;Cao, L;Zou, F;Zhang, Z;
Pulmonary pharmacology & therapeutics
Species: Mouse
Sample Types: Tissue Homogenates
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NLRC5 Deficiency Reduces LPS-Induced Microglial Activation via Inhibition of NF-?B Signaling and Ameliorates Mice's Depressive-like Behavior
Authors: Sun, C;Shen, Y;Liu, P;Shen, Y;Hu, Y;Li, P;Zhang, Y;Miao, F;Zhang, J;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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The cGAS-STING-YY1 axis accelerates progression of neurodegeneration in a mouse model of Parkinson's disease via LCN2-dependent astrocyte senescence
Authors: Jiang, SY;Tian, T;Yao, H;Xia, XM;Wang, C;Cao, L;Hu, G;Du, RH;Lu, M;
Cell death and differentiation
Species: Mouse
Sample Types: Cell Culture Supernates, Tissue Homogenates
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JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders
Authors: Ambrus-Aikelin, G;Takeda, K;Joetham, A;Lazic, M;Povero, D;Santini, AM;Pranadinata, R;Johnson, CD;McGeough, MD;Beasley, FC;Stansfield, R;McBride, C;Trzoss, L;Hoffman, HM;Feldstein, AE;Stafford, JA;Veal, JM;Bain, G;Gelfand, EW;
Scientific reports
Species: Mouse
Sample Types: Plasma
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A Novel Therapeutic Formulation for the Improved Treatment of Indian Red Scorpion (Mesobuthus tamulus) Venom-Induced Toxicity-Tested in Caenorhabditis elegans and Rodent Models
Authors: Das, B;Madhubala, D;Mahanta, S;Patra, A;Puzari, U;Khan, MR;Mukherjee, AK;
Toxins
Species: Mouse
Sample Types: Plasma
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Aloe-Emodin Ameliorates Cecal Ligation and Puncture-Induced Sepsis
Authors: Su, J;Chen, S;Xiao, J;Feng, Z;Hu, S;Su, Q;Chen, Q;Chen, D;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates, Serum, Tissue Homogenates
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Cold-induced adaptive thermogenesis is impaired by exposure of Asian sand dust in mice
Authors: Bagon, BB;Lee, J;Matienzo, ME;Lee, SJ;Pak, SW;Kim, K;Lee, J;Lee, CM;Shin, IS;Moon, C;Park, MJ;Kim, DI;
Journal of thermal biology
Species: Mouse
Sample Types: BALF
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Glutathione trisulfide prevents lipopolysaccharide-induced retinal inflammation via inhibition of proinflammatory cytokine production in glial cells
Authors: Tawarayama, H;Umeki, K;Inoue-Yanagimachi, M;Takahashi, N;Hasegawa, H;Himori, N;Tsuda, S;Kunikata, H;Akaike, T;Nakazawa, T;
Scientific reports
Species: Mouse
Sample Types: Cell Culture Supernates
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Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice
Authors: Schwarz, MM;Ganaie, SS;Feng, A;Brown, G;Yangdon, T;White, JM;Hoehl, RM;McMillen, CM;Rush, RE;Connors, KA;Cui, X;Leung, DW;Egawa, T;Amarasinghe, GK;Hartman, AL;
Science advances
Species: Mouse
Sample Types: Tissue Homogenates
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Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages
Authors: Lin, JB;Mora, A;Wang, TJ;Santeford, A;Usmani, D;Ligon, MM;Mysorekar, IU;Apte, RS;
mBio
Species: Mouse
Sample Types: Cell Culture Supernates
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Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells
Authors: Jadi, PK;Dave, A;Issa, R;Tabbasum, K;Okurowska, K;Samarth, A;Urwin, L;Green, LR;Partridge, LJ;MacNeil, S;Garg, P;Monk, PN;Roy, S;
The ocular surface
Species: Mouse
Sample Types: Tissue Homogenates
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Anti-inflammatory effects of Allium cepa L. peel extracts via inhibition of JAK-STAT pathway in LPS-stimulated RAW264.7 cells
Authors: Lee, HS;Kwon, YJ;Seo, EB;Kim, SK;Lee, H;Lee, JT;Chang, PS;Choi, YJ;Lee, SH;Ye, SK;
Journal of ethnopharmacology
Species: Mouse
Sample Types: Cell Culture Supernates
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Leucine zipper protein 1 prevents doxorubicin-induced cardiotoxicity in mice
Authors: Fan, D;Jin, Z;Cao, J;Li, Y;He, T;Zhang, W;Peng, L;Liu, H;Wu, X;Chen, M;Fan, Y;He, B;Yu, W;Wang, H;Hu, X;Lu, Z;
Redox biology
Species: Mouse, Transgenic Mouse
Sample Types: Tissue Homogenates
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Qinzhu Liangxue inhibits IL-6-induced hyperproliferation and inflammation in HaCaT cells by regulating METTL14/SOCS3/STAT3 axis
Authors: Chen, Y;Miao, X;Xiang, Y;Kuai, L;Ding, X;Ma, T;Li, B;Fan, B;
Journal of ethnopharmacology
Species: Mouse
Sample Types: Serum
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Cardiomyocyte peroxisome proliferator-activated receptor ? prevents septic cardiomyopathy via improving mitochondrial function
Authors: Zhu, XX;Wang, X;Jiao, SY;Liu, Y;Shi, L;Xu, Q;Wang, JJ;Chen, YE;Zhang, Q;Song, YT;Wei, M;Yu, BQ;Fielitz, J;Gonzalez, FJ;Du, J;Qu, AJ;
Acta pharmacologica Sinica
Species: Mouse
Sample Types: Plasma
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Antidiabetic and Immunoregulatory Activities of Extract of Phyllanthus emblica L. in NOD with Spontaneous and Cyclophosphamide-Accelerated Diabetic Mice
Authors: Lin, CH;Kuo, YH;Shih, CC;
International journal of molecular sciences
Species: Mouse
Sample Types:
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Amelioration of Murine Colitis by Attenuated Salmonella choleraesuis Encoding Interleukin-19
Authors: Chen, SY;Chu, CT;Yang, ML;Lin, JD;Wang, CT;Lee, CH;Lin, IC;Shiau, AL;Ling, P;Wu, CL;
Microorganisms
Species: Mouse
Sample Types: Tissue Homogenates
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Parthenolide targets NLRP3 to treat inflammasome-related diseases
Authors: Liu, L;Feng, L;Gao, J;Hu, J;Li, A;Zhu, Y;Zhang, C;Qiu, B;Shen, Z;
International immunopharmacology
Species: Mouse
Sample Types: Cell Culture Supernates, Serum
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Endosomal trafficking of two-pore K+ efflux channel TWIK2 to plasmalemma mediates NLRP3 inflammasome activation and inflammatory injury
Authors: Huang, LS;Anas, M;Xu, J;Zhou, B;Toth, PT;Krishnan, Y;Di, A;Malik, AB;
eLife
Species: Mouse
Sample Types: Cell Culture Supernates
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LPS-induced mitochondrial dysfunction regulates innate immunity activation and alpha-synuclein oligomerization in Parkinson's disease
Authors: AR Esteves, DF Silva, D Banha, E Candeias, B Guedes, SM Cardoso
Redox Biology, 2023-04-25;63(0):102714.
Species: Mouse
Sample Types: Cell Lysates
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An IL-6/STAT3/MR/FGF21 axis mediates heart-liver cross-talk after myocardial infarction
Authors: JY Sun, LJ Du, XR Shi, YY Zhang, Y Liu, YL Wang, BY Chen, T Liu, H Zhu, Y Liu, CC Ruan, Z Gan, H Ying, Z Yin, PJ Gao, X Yan, RG Li, SZ Duan
Science Advances, 2023-04-05;9(14):eade4110.
Species: Mouse
Sample Types: Plasma
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Novel neuroendocrine role of gamma-aminobutyric acid and gastrin releasing peptide in the host response to influenza infection
Authors: K Ann Shirey, W Lai, M Sunday, F Cuttitta, J Cg Blanco, SN Vogel
Mucosal Immunology, 2023-03-24;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Salidroside attenuates lipopolysaccharide-induced neuroinflammation and cognitive impairment in septic encephalopathy mice
Authors: L Xiao, L Li, J Huang, Y Luan, J Pan, Y Gai, Z Xu
International immunopharmacology, 2023-03-20;117(0):109975.
Species: Mouse
Sample Types: Serum
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Honokiol reduces fungal burden and ameliorate inflammation lesions of Aspergillus fumigatus keratitis via Dectin-2 down-regulation
Authors: L Zhan, X Tian, J Lin, Y Zhang, H Zheng, X Peng, G Zhao
International immunopharmacology, 2023-03-16;118(0):109849.
Species: Mouse
Sample Types: Cell culture supernate
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Increased hepatic interleukin-1, arachidonic acid, and reactive oxygen species mediate the protective potential of peptides shared by gut cysteine peptidases against Schistosoma mansoni infection in mice
Authors: H Tallima, R El Ridi
PloS Neglected Tropical Diseases, 2023-03-15;17(3):e0011164.
Species: Mouse
Sample Types: Tissue Homogenates
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Mitochondrial calcium uptake 3 mitigates cerebral amyloid angiopathy-related neuronal death and glial inflammation by reducing mitochondrial dysfunction
Authors: G Zhou, Q Ye, Y Xu, B He, L Wu, G Zhu, J Xie, L Yao, Z Xiao
International immunopharmacology, 2023-03-04;117(0):109614.
Species: Mouse
Sample Types: Tissue Homogenates
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Novel NF-kappaB reporter mouse for the non-invasive monitoring of inflammatory diseases
Authors: SY Park, MW Kim, JH Kang, HJ Jung, JH Hwang, SJ Yang, JK Woo, Y Jeon, H Lee, YS Yoon, JK Seong, SH Oh
Scientific Reports, 2023-03-02;13(1):3556.
Species: Mouse
Sample Types: Serum
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SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice
Authors: FL Fontes-Dan, GG Fernandes, EG Gutman, EV De Lima, LS Antonio, MB Hammerle, HP Mota-Arauj, LC Colodeti, SMB Araújo, GM Froz, TN da Silva, LA Duarte, AL Salvio, KL Pires, LAA Leon, CCF Vasconcelo, L Romão, LEB Savio, JL Silva, R da Costa, JR Clarke, AT Da Poian, SV Alves-Leon, GF Passos, CP Figueiredo
Cell Reports, 2023-02-17;42(3):112189.
Species: Mouse
Sample Types: Cell Culture Supernates
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Exosome-Based Delivery of Super-Repressor IkappaBalpha Alleviates Alcohol-Associated Liver Injury in Mice
Authors: HH Kim, YR Shim, SE Choi, TE Falana, JK Yoo, SH Ahn, M Park, H Seo, C Choi, WI Jeong
Pharmaceutics, 2023-02-14;15(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Thymosin Beta 4 Inhibits LPS and ATP-Induced Hepatic Stellate Cells via the Regulation of Multiple Signaling Pathways
Authors: J Choi, Y Cho, H Choi, S Lee, H Han, J Lee, J Kwon
International Journal of Molecular Sciences, 2023-02-08;24(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
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ATF5 Attenuates the Secretion of Pro-Inflammatory Cytokines in Activated Microglia
Authors: J Zhu, MJ Lee, JH An, E Oh, W Chung, JY Heo
International Journal of Molecular Sciences, 2023-02-07;24(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-inflammatory effect and signaling mechanism of 8-shogaol and 10-shogaol in a dextran sodium sulfate-induced colitis mouse model
Authors: HR Kim, EM Noh, SY Kim
Heliyon, 2023-01-05;9(1):e12778.
Species: Mouse
Sample Types: Serum
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A�ai Berry Administration Promotes Wound Healing through Wnt/beta-Catenin Pathway
Authors: L Interdonat, Y Marino, GA Franco, A Arangia, R D'Amico, R Siracusa, M Cordaro, D Impellizze, R Fusco, S Cuzzocrea, RD Paola
International Journal of Molecular Sciences, 2023-01-03;24(1):.
Species: Mouse
Sample Types: Tissue Homogenates
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Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice
Authors: YH Kwon, S Banskota, H Wang, L Rossi, JA Grondin, SA Syed, Y Yousefi, JD Schertzer, KM Morrison, MG Wade, AC Holloway, MG Surette, GR Steinberg, WI Khan
Nature Communications, 2022-12-20;13(1):7617.
Species: Mouse
Sample Types: Whole Tissue
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The Effects of Synthetic SREBP-1 and PPAR-gamma Decoy Oligodeoxynucleotide on Acne-like Disease In Vivo and In Vitro via Lipogenic Regulation
Authors: H Gu, HJ An, MG Gwon, S Bae, CC Zouboulis, KK Park
Biomolecules, 2022-12-12;12(12):.
Species: Mouse
Sample Types: Serum
-
Inflammation promotes synucleinopathy propagation
Authors: TK Kim, EJ Bae, BC Jung, M Choi, SJ Shin, SJ Park, JT Kim, MK Jung, A Ulusoy, MY Song, JS Lee, HJ Lee, DA Di Monte, SJ Lee
Experimental & Molecular Medicine, 2022-12-06;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Aberrant expression and localization of the RAP1 shelterin protein contribute to age-related phenotypes
Authors: AJ Stock, RA McDevitt, C Puligilla, Y Wang, Y Zhang, K Wang, C Sun, KG Becker, E Lehrmann, WH Wood, Y Gong, M Aqdas, MH Sung, V Hoffmann, C Liu, M Gorospe, L Harrington, L Ferrucci, Y Liu
PloS Genetics, 2022-11-28;18(11):e1010506.
Species: Mouse
Sample Types: Tissue Homogenates
-
Efficacy of Clinically Used PARP Inhibitors in a Murine Model of Acute Lung Injury
Authors: V Martins, SS Santos, LOCP Rodrigues, R Salomao, L Liaudet, C Szabo
Cells, 2022-11-26;11(23):.
Species: Mouse
Sample Types: BALF
-
GPSM1 impairs metabolic homeostasis by controlling a pro-inflammatory pathway in macrophages
Authors: J Yan, Y Zhang, H Yu, Y Zong, D Wang, J Zheng, L Jin, X Yu, C Liu, Y Zhang, F Jiang, R Zhang, X Fang, T Xu, M Li, J Di, Y Lu, X Ma, J Zhang, W Jia, C Hu
Nature Communications, 2022-11-25;13(1):7260.
Species: Mouse
Sample Types: Serum
-
RasGRP1 promotes the acute inflammatory response and restricts inflammation-associated cancer cell growth
Authors: C Wang, X Li, B Xue, C Yu, L Wang, R Deng, H Liu, Z Chen, Y Zhang, S Fan, C Zuo, H Sun, H Zhu, J Wang, S Tang
Nature Communications, 2022-11-16;13(1):7001.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Attenuation of hepatic fibrosis by p-Coumaric acid via modulation of NLRP3 inflammasome activation in C57BL/6 mice
Authors: TMT Truong, SH Seo, S Chung, I Kang
The Journal of nutritional biochemistry, 2022-11-15;0(0):109204.
Species: Mouse
Sample Types: Plasma
-
Cynapanoside A exerts protective effects against obesity-induced diabetic nephropathy through ameliorating TRIM31-mediated inflammation, lipid synthesis and fibrosis
Authors: J Luo, J Tan, J Zhao, L Wang, J Liu, X Dai, Y Sun, Q Kuang, J Hui, J Chen, G Kuang, S Chen, Y Wang, C Ge, M Xu
International immunopharmacology, 2022-11-11;113(0):109395.
Species: Mouse
Sample Types: Serum
-
Motor neuron survival is associated with reduced neuroinflammation and increased autophagy after brachial plexus avulsion injury in aldose reductase-deficient mice
Authors: K Zhong, Y Huang, PLM Zilundu, Y Wang, Y Zhou, G Yu, R Fu, SK Chung, Y Tang, X Cheng, L Zhou
Journal of Neuroinflammation, 2022-11-09;19(1):271.
Species: Mouse
Sample Types: Tissue Homogenates
-
Ubiquitin?specific protease 8 ameliorates lipopolysaccharide?induced spleen injury via suppression of NF?kappaB and MAPK signaling pathways
Authors: W Bi, J Zhang, Z Zeng, R Zhou, J Zhao, W Yan, L Wang, X Li, L Zhu
Molecular Medicine Reports, 2022-11-02;26(6):.
Species: Mouse
Sample Types: Serum
-
Macrophage Sprouty4 deficiency diminishes sepsis-induced acute lung injury in mice
Authors: R Chen, C Cao, H Liu, W Jiang, R Pan, H He, K Ding, Q Meng
Redox Biology, 2022-10-22;58(0):102513.
Species: Mouse
Sample Types: BALF
-
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy
Authors: ZM Howard, CK Gomatam, CP Rabolli, J Lowe, AB Piepho, SS Bansal, F Accornero, JA Rafael-For
JCI Insight, 2022-10-10;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Hepatocyte phosphatase DUSP22 mitigates NASH-HCC progression by targeting FAK
Authors: C Ge, J Tan, X Dai, Q Kuang, S Zhong, L Lai, C Yi, Y Sun, J Luo, C Zhang, L Zhu, B Wang, M Xu
Oncogene, 2022-10-08;13(1):5945.
Species: Mouse
Sample Types: Serum
-
Vathasura Kudineer, an Andrographis based polyherbal formulation exhibits immunomodulation and inhibits chikungunya virus (CHIKV) under in-vitro conditions
Authors: A Hasan, S Devi Ms, G Sharma, V Narayanan, P Sathiyaraj, S Vinayak, S Sunil
Journal of ethnopharmacology, 2022-09-29;0(0):115762.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or KATP channels inhibitors
Authors: M Shayan, F Eslami, A Amanlou, S Solaimania, N Rahimi, A Rashidian, S Ejtemaei-M, M Ghasemi, AR Dehpour
Toxicology and Applied Pharmacology, 2022-09-23;454(0):116254.
Species: Mouse
Sample Types: Tissue Homogenates
-
Targeting the succinate receptor effectively inhibits periodontitis
Authors: Y Guo, F Xu, SC Thomas, Y Zhang, B Paul, S Sakilam, S Chae, P Li, C Almeter, AR Kamer, P Arora, DT Graves, D Saxena, X Li
Cell Reports, 2022-09-20;40(12):111389.
Species: Mouse
Sample Types: Serum
-
Modification of the immune response by bacteriophages alters methicillin-resistant Staphylococcus aureus infection
Authors: T Suda, T Hanawa, M Tanaka, Y Tanji, K Miyanaga, S Hasegawa-I, K Shirato, T Kizaki, T Matsuda
Scientific Reports, 2022-09-19;12(1):15656.
Species: Mouse
Sample Types: Tissue Lysates
-
Maternal high-fat diet promotes calcified atherosclerotic plaque formation in adult offspring by enhancing transformation of VSMCs to osteochondrocytic-like phenotype
Authors: D Miyawaki, H Yamada, M Saburi, N Wada, S Motoyama, T Sugimoto, H Kubota, N Wakana, D Kami, T Ogata, S Matoba
Heliyon, 2022-09-15;8(9):e10644.
Species: Transgenic Mouse
Sample Types: Serum
-
Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis
Authors: X Zhang, SK Misra, P Moitra, X Zhang, SJ Jeong, J Stitham, A Rodriguez-, A Park, YS Yeh, WE Gillanders, D Fan, A Diwan, J Cho, S Epelman, IJ Lodhi, D Pan, B Razani
Autophagy, 2022-08-18;0(0):1-18.
Species: Mouse
Sample Types: Cell Culture Supenates
-
Synthesis and NLRP3-Inflammasome Inhibitory Activity of the Naturally Occurring Velutone F and of Its Non-Natural Regioisomeric Chalconoids
Authors: T De Ventura, M Perrone, S Missiroli, P Pinton, P Marchetti, G Strazzabos, G Turrin, D Illuminati, V Cristofori, A Fantinati, M Fabbri, C Giorgi, C Trapella, V Zanirato
International Journal of Molecular Sciences, 2022-08-11;23(16):.
Species: Mouse
Sample Types: Plasma
-
Sensitization of GSH synthesis by curcumin curtails acrolein-induced alveolar epithelial apoptosis via Keap1 cysteine conjugation: A randomized controlled trial and experimental animal model of pneumonitis
Authors: E Hee Jo, J Eun Moon, M Han Chang, Y Jin Lim, J Hyun Park, S Hee Lee, Y Rae Cho, AE Cho, S Pil Pack, HW Kim, L Crowley, B Le, AB Nukhet, Y Chen, Y Zhong, J Zhao, Y Li, H Cha, J Hoon Pan, J Kyeom Kim, J Hyup Lee
Journal of advanced research, 2022-06-27;0(0):.
Species: Mouse
Sample Types: Plasma
-
Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction
Authors: JK Sterling, B Baumann, S Foshe, A Voigt, S Guttha, A Alnemri, SJ McCright, M Li, RJ Zauhar, SR Montezuma, RJ Kapphahn, VRM Chavali, DA Hill, DA Ferrington, D Stambolian, RF Mullins, D Merrick, JL Dunaief
Cell Reports, 2022-06-14;39(11):110942.
Species: Mouse
Sample Types: Serum
-
Gasdermin D Deficiency Limits the Transition of Atherosclerotic Plaques to an Inflammatory Phenotype in ApoE Knock-Out Mice
Authors: P Puylaert, M Van Praet, F Vaes, CHG Neutel, L Roth, PJ Guns, GRY De Meyer, W Martinet
Biomedicines, 2022-05-19;10(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Alleviation of Gut Microbiota-Induced Depression and Colitis in Mice by Anti-Inflammatory Probiotics NK151, NK173, and NK175
Authors: JW Yoo, YJ Shin, X Ma, YH Son, HM Jang, CK Lee, DH Kim
Nutrients, 2022-05-16;14(10):.
Species: Mouse
Sample Types: Tissue Lysates
-
MicroRNA-299a-5p Protects against Spinal Cord Injury through Activating AMPK Pathway
Authors: ZZ Zhang, SY Xian, C Bao, F Chen
Oxidative Medicine and Cellular Longevity, 2022-05-13;2022(0):8659587.
Species: Mouse
Sample Types: Tissue Homogenates
-
Hypercoagulability Impairs Plaque Stability in Diabetes-Induced Atherosclerosis
Authors: S Ambreen, S Fatima, A Elwakiel, R Rana, K Singh, A Gupta, D Gupta, H Khawaja, J Manoharan, C Besler, U Laufs, S Kohli, B Isermann, K Shahzad
Nutrients, 2022-05-10;14(10):.
Species: Mouse
Sample Types: Plasma
-
High-fructose corn syrup promotes proinflammatory Macrophage activation via ROS-mediated NF-kappaB signaling and exacerbates colitis in mice
Authors: L Wang, T Ji, Y Yuan, H Fu, Y Wang, S Tian, J Hu, L Wang, Z Wang
International immunopharmacology, 2022-05-06;109(0):108814.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TH17 cells promote CNS inflammation by sensing danger signals via Mincle
Authors: Q Zhang, W Liu, H Wang, H Zhou, K Bulek, X Chen, CJ Zhang, J Zhao, R Zhang, C Liu, Z Kang, RA Bermel, G Dubyak, DW Abbott, TS Xiao, LE Nagy, X Li
Nature Communications, 2022-05-03;13(1):2406.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation
Authors: LK Billingham, JS Stoolman, K Vasan, AE Rodriguez, TA Poor, M Szibor, HT Jacobs, CR Reczek, A Rashidi, P Zhang, J Miska, NS Chandel
Nature Immunology, 2022-04-28;0(0):.
Species: Mouse
Sample Types: Serum
-
Amyloid-beta activates NLRP3 inflammasomes by affecting microglial immunometabolism through the Syk-AMPK pathway
Authors: ES Jung, K Suh, J Han, H Kim, HS Kang, WS Choi, I Mook-Jung
Aging Cell, 2022-04-27;0(0):e13623.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation
Authors: Y Wang, C Chen, J Chen, T Sang, H Peng, X Lin, Q Zhao, S Chen, T Eling, X Wang
Redox Biology, 2022-04-27;52(0):102322.
Species: Mouse
Sample Types: Serum
-
Renoprotective effects of ferric citrate in a mouse model of chronic kidney disease
Authors: MR Hanudel, B Czaya, S Wong, G Jung, K Chua, B Qiao, V Gabayan, T Ganz
Scientific Reports, 2022-04-23;12(1):6695.
Species: Mouse
Sample Types:
-
Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues
Authors: A Daghrery, JA Ferreira, J Xu, N Golafshan, D Kaigler, SB Bhaduri, J Malda, M Castilho, MC Bottino
Bioactive materials, 2022-04-22;19(0):268-281.
Species: Mouse
Sample Types: Cell Culture Supernates
-
S-Acetyl-Glutathione Attenuates Carbon Tetrachloride-Induced Liver Injury by Modulating Oxidative Imbalance and Inflammation
Authors: R Di Paola, S Modafferi, R Siracusa, M Cordaro, R D'Amico, ML Ontario, L Interdonat, AT Salinaro, R Fusco, D Impellizze, V Calabrese, S Cuzzocrea
International Journal of Molecular Sciences, 2022-04-17;23(8):.
Species: Mouse
Sample Types: Serum
-
Dynamic synovial fibroblasts are modulated by NBCn1 as a potential target in rheumatoid arthritis
Authors: M Ji, HJ Ryu, HM Baek, DM Shin, JH Hong
Experimental & Molecular Medicine, 2022-04-12;0(0):.
Species: Mouse
Sample Types: Plasma
-
RANKL Impairs the TLR4 Pathway by Increasing TRAF6 and RANK Interaction in Macrophages
Authors: RF Mota, PH Cavalcanti, MER Cezine, FS Matsuo, RJM Metzner, CA Oliveira d, KC Peronni, H Hayashi, M Shimamura, H Nakagami, MK Osako
BioMed Research International, 2022-04-12;2022(0):7740079.
Species: Human, Mouse, Transgenic Mouse
Sample Types: Cell Culture Supernates
-
SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell autonomous hippocampal neuronal death
Authors: J Oh, WH Cho, E Barcelon, KH Kim, J Hong, SJ Lee
Scientific Reports, 2022-03-31;12(1):5496.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3beta-Nrf2 pathway
Authors: K Huo, KG Ma, QY Guo, P Duan, J Xu
International immunopharmacology, 2022-03-31;108(0):108718.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cucurbitacin E glucoside alleviates concanavalin A-induced hepatitis through enhancing SIRT1/Nrf2/HO-1 and inhibiting NF-?B/NLRP3 signaling pathways
Authors: GA Mohamed, SRM Ibrahim, DS El-Agamy, WM Elsaed, A Sirwi, HZ Asfour, AE Koshak, SS Elhady
Journal of ethnopharmacology, 2022-03-27;292(0):115223.
Species: Mouse
Sample Types: Tissue Homogenates
-
Critical role of FPR1 in splenocyte migration into brain to worsen inflammation and ischemic brain injury in mice
Authors: J Li, MD Chordia, Y Zhang, H Zong, D Pan, Z Zuo
Theranostics, 2022-03-21;12(7):3024-3044.
Species: Mouse
Sample Types: Tissue Homogenates
-
GSPE Protects against Bleomycin-Induced Pulmonary Fibrosis in Mice via Ameliorating Epithelial Apoptosis through Inhibition of Oxidative Stress
Authors: OJ Sul, JH Kim, T Lee, KW Seo, HJ Cha, B Kwon, JJ Ahn, YS Cho, YM Oh, Y Jegal, SW Ra
Oxidative Medicine and Cellular Longevity, 2022-03-20;2022(0):8200189.
Species: Mouse
Sample Types: Tissue Homogenates
-
Pharmacological Inhibition of Glutaminase 1 Attenuates Alkali-Induced Corneal Neovascularization by Modulating Macrophages
Authors: Y Feng, X Yang, J Huang, M Shen, L Wang, X Chen, Y Yuan, C Dong, X Ma, F Yuan
Oxidative Medicine and Cellular Longevity, 2022-03-19;2022(0):1106313.
Species: Mouse
Sample Types: Protein
-
Strongylocentrotus nudus Eggs Polysaccharide Enhances Macrophage Phagocytosis Against E.coli Infection by TLR4/STAT3 Axis
Authors: X Tian, M Guo, X Zhang, L Guo, N Lan, Y Cheng, Y Han, M Wang, Z Peng, C Zhou, H Fan
Frontiers in Pharmacology, 2022-03-17;13(0):807440.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cytokines and Neurodegeneration in Epileptogenesis
Authors: P Wolinski, D Ksiazek-Wi, A Glabinski
Brain sciences, 2022-03-12;12(3):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Povidone iodine suppresses LPS-induced inflammation by inhibiting TLR4/MyD88 formation in airway epithelial cells
Authors: SH Lee, MR Choi, J Chung, SH Choi, SK Park, YM Kim
Scientific Reports, 2022-03-07;12(1):3681.
Species: Mouse
Sample Types: Nasal Lavage Fluid
-
Fatty Acid Amide Hydrolase (FAAH) Inhibition Plays a Key Role in Counteracting Acute Lung Injury
Authors: T Genovese, A Duranti, R D'Amico, R Fusco, D Impellizze, AF Peritore, R Crupi, E Gugliandol, S Cuzzocrea, R Di Paola, R Siracusa, M Cordaro
International Journal of Molecular Sciences, 2022-03-03;23(5):.
Species: Mouse
Sample Types: Alveolar Fluid
-
Serum Amyloid A1 Exacerbates Hepatic Steatosis via TLR4 Mediated NF-kappaB Signaling Pathway
Authors: B Jiang, D Wang, Y Hu, W Li, F Liu, X Zhu, X Li, H Zhang, H Bai, Q Yang, X Yang, J Ben, Q Chen
Molecular Metabolism, 2022-03-03;0(0):101462.
Species: Mouse
Sample Types: Plasma
-
Kakonein restores hyperglycemia-induced macrophage digestion dysfunction through regulation of cathepsin B-dependent NLRP3 inflammasome activation
Authors: D Lian, L Zhu, Y Yu, X Zhang, Y Lin, J Liu, R Han, Y Guo, D Cai, W Xiao, Y Chen, H He, D Xu, C Zheng, X Wang, Y Huang, Y Chen
Journal of leukocyte biology, 2022-02-27;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes
Authors: M Xu, J Tan, W Dong, B Zou, X Teng, L Zhu, C Ge, X Dai, Q Kuang, S Zhong, L Lai, C Yi, T Tang, J Zhao, L Wang, J Liu, H Wei, Y Sun, Q Yang, Q Li, D Lou, L Hu, X Liu, G Kuang, J Luo, M Xiong, J Feng, C Zhang, B Wang
Nature Communications, 2022-02-25;13(1):1052.
Species: Mouse
Sample Types: Serum
-
Palmatine attenuates the doxorubicin-induced inflammatory response, oxidative damage and cardiomyocyte apoptosis
Authors: D Cheng, P Liu, Z Wang
International immunopharmacology, 2022-02-09;106(0):108583.
Species: Mouse
Sample Types: Serum
-
Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1
Authors: K Peukert, F Steinhagen, M Fox, C Feuerborn, S Schulz, B Seeliger, P Schuss, M Schneider, S Frede, A Sauer, C Putensen, E Latz, C Wilhelm, C Bode
Respiratory Research, 2022-02-07;23(1):21.
Species: Mouse
Sample Types: BALF
-
2-Chlorodeoxyadenosine (Cladribine) preferentially inhibits the biological activity of microglial cells
Authors: F Aybar, M Julia Pere, M Silvina Ma, M Eugenia Sa, M Marrodan, J María Pasq, J Correale
International immunopharmacology, 2022-01-29;105(0):108571.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Maternal P2X7 receptor inhibition prevents autism-like phenotype in male mouse offspring through the NLRP3-IL-1beta pathway
Authors: D Szabó, P Tod, F Gölöncsér, V Román, B Lendvai, L Otrokocsi, B Sperlágh
Brain, Behavior, and Immunity, 2022-01-20;0(0):.
Species: Mouse
Sample Types: Plasma
-
Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies
Authors: M Kamiya, F Mizoguchi, K Kawahata, D Wang, M Nishibori, J Day, C Louis, IP Wicks, H Kohsaka, S Yasuda
Nature Communications, 2022-01-10;13(1):166.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gasdermin D pores are dynamically regulated by local phosphoinositide circuitry
Authors: AB Santa Cruz, KP Schnur, AB Malik, GCH Mo
Nature Communications, 2022-01-10;13(1):52.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Liensinine alleviates high fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) through suppressing oxidative stress and inflammation via regulating TAK1/AMPK signaling
Authors: L Liang, S Ye, R Jiang, X Zhou, J Zhou, S Meng
International immunopharmacology, 2022-01-06;104(0):108306.
Species: Mouse
Sample Types: Serum
-
Brain-specific TRAF7 deletion ameliorates traumatic brain injury by suppressing MEKK3-regulated glial inflammation and neuronal death
Authors: Y Yuxiong, X Xujin, T Yi, C Ya, L Yujuan, H Shanshan, W Huiwen
International immunopharmacology, 2021-12-23;103(0):108219.
Species: Transgenic Mouse
Sample Types: Tissue Homogenates
-
Bruton's tyrosine kinase drives neuroinflammation and anxiogenic behavior in mouse models of stress
Authors: S Ghosh, Z Mohammed, I Singh
Journal of Neuroinflammation, 2021-12-11;18(1):289.
Species: Mouse
Sample Types: Tissue Homogenates
-
Exercise Inhibits NLRP3 Inflammasome Activation in Obese Mice via the Anti-Inflammatory Effect of Meteorin-like
Authors: HMA Javaid, NE Sahar, DL ZhuGe, JY Huh
Cells, 2021-12-09;10(12):.
Species: Mouse
Sample Types: Plasma
-
Targeting MicroRNA-485-3p Blocks Alzheimer's Disease Progression
Authors: HS Koh, S Lee, HJ Lee, JW Min, T Iwatsubo, CE Teunissen, HJ Cho, JH Ryu
International Journal of Molecular Sciences, 2021-12-04;22(23):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Epac-2 ameliorates spontaneous colitis in Il-10-/- mice by protecting the intestinal barrier and suppressing NF-kappaB/MAPK signalling
Authors: X Song, H Wen, L Zuo, Z Geng, J Nian, L Wang, Y Jiang, J Tao, Z Zhu, X Wu, Z Wang, X Zhang, L Yu, H Zhao, P Xiang, J Li, L Shen, J Hu
Journal of Cellular and Molecular Medicine, 2021-12-03;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Exercise-Induced Irisin Decreases Inflammation and Improves NAFLD by Competitive Binding with MD2
Authors: W Zhu, NE Sahar, HMA Javaid, ES Pak, G Liang, Y Wang, H Ha, JY Huh
Cells, 2021-11-25;10(12):.
Species: Human
Sample Types: Tissue Homogenates
-
Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages
Authors: X Ding, H Kambara, R Guo, A Kanneganti, M Acosta-Zal, J Li, F Liu, T Bei, W Qi, X Xie, W Han, N Liu, C Zhang, X Zhang, H Yu, L Zhao, F Ma, JR Köhler, HR Luo
Nature Communications, 2021-11-18;12(1):6699.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chemical inducer of regucalcin attenuates lipopolysaccharide-induced inflammatory responses in pancreatic MIN6 beta-cells and RAW264.7 macrophages
Authors: T Murata, K Hashimoto, S Kohno, C Takahashi, M Yamaguchi, C Ito, M Itoigawa, R Kojima, K Hikita, N Kaneda
FEBS Open Bio, 2021-11-09;0(0):.
Species: Mouse
Sample Types: Cell Culture Media
-
Atractylenolide-III suppresses lipopolysaccharide-induced inflammation via downregulation of toll-like receptor 4 in mouse microglia
Authors: E Novianti, G Katsuura, N Kawamura, A Asakawa, A Inui
Heliyon, 2021-10-27;7(10):e08269.
Species: Mouse
Sample Types: Cell Culture Supernates
-
All?trans retinoic acid promotes macrophage phagocytosis and decreases inflammation via inhibiting CD14/TLR4 in acute lung injury
Authors: S Li, Y Lei, J Lei, H Li
Molecular Medicine Reports, 2021-10-22;24(6):.
Species: Mouse
Sample Types: Plasma
-
A Novel Para-Amino Salicylic Acid Magnesium Layered Hydroxide Nanocomposite Anti-Tuberculosis Drug Delivery System with Enhanced in vitro Therapeutic and Anti-Inflammatory Properties
Authors: B Saifullah, P Arulselvan, ME El Zowalat, WS Tan, S Fakurazi, TJ Webster, R Baby, MZ Hussein
International Journal of Nanomedicine, 2021-10-15;16(0):7035-7050.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-fibrotic effect of Pycnogenol� in a polyhexamethylene guanidine-treated mouse model
Authors: CM Park, HY Kim, D Jeon, YJ Shin, IH Kim, SJ Choi, KC Kim, K Lee, SH Kim, MS Kim
Respiratory physiology & neurobiology, 2021-10-12;0(0):103802.
Species: Mouse
Sample Types: Tissue Homogenates
-
Short-term effect of ligature-induced periodontitis on cardiovascular variability and inflammatory response in spontaneously hypertensive rats
Authors: AB Ribeiro, TM da Silva, NN Santos-Jún, JA Castania, R Fazan, HC Salgado
BMC Oral Health, 2021-10-11;21(1):515.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment
Authors: Y Wang, X Zhao, M Gao, X Wan, Y Guo, Y Qu, Y Chen, T Li, H Liu, M Jiang, F Wang, X Sun
Cell Death & Disease, 2021-10-09;12(10):926.
Species: Mouse
Sample Types: Tissue Lysates
-
Aerobic exercise inhibits inflammatory response in atherosclerosis via Sestrin1 protein
Authors: Y Sun, Y Wu, Y Jiang, H Liu
Experimental gerontology, 2021-10-08;155(0):111581.
Species: Transgenic Mouse
Sample Types: Cell Lysates
-
Mechanism of chlorogenic acid in alveolar macrophage polarization in Klebsiella pneumoniae-induced pneumonia
Authors: QR Li, SR Tan, L Yang, W He, L Chen, FX Shen, Z Wang, HF Wang
Journal of leukocyte biology, 2021-09-29;0(0):.
Species: Mouse
Sample Types: BALF
-
The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection
Authors: NA Loeven, AI Perault, PA Cotter, CA Hodges, JD Schwartzma, TH Hampton, JB Bliska
MBio, 2021-09-28;0(0):e0209821.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NLRP3 Inflammasome Is Involved in Cocaine-Mediated Potentiation on Behavioral Changes in CX3CR1-Deficient Mice
Authors: ML Guo, ET Chivero, SE Callen, S Buch
Journal of personalized medicine, 2021-09-27;11(10):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Antiatherosclerotic effect of dehydrocorydaline on ApoE-/- mice: inhibition of macrophage inflammation
Authors: B Wen, YY Dang, SH Wu, YM Huang, KY Ma, YM Xu, XL Zheng, XY Dai
Acta pharmacologica Sinica, 2021-09-22;0(0):.
Species: Mouse
Sample Types: Plasma
-
TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage
Authors: P Xu, C Tao, Y Zhu, G Wang, L Kong, W Li, R Li, J Li, C Zhang, L Wang, X Liu, W Sun, W Hu
Journal of Neuroinflammation, 2021-08-30;18(1):188.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF-kappaB Signaling
Authors: Y Hou, X Xiao, W Yu, S Qi
Journal of Immunology Research, 2021-08-24;2021(0):4754454.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes
Authors: S Lee, A Ishitsuka, T Kuroki, YH Lin, A Shibuya, T Hongu, Y Funakoshi, Y Kanaho, K Nagata, A Kawaguchi
JCI Insight, 2021-08-23;6(16):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Distinct pro-inflammatory properties of myeloid cell-derived apolipoprotein E2 and E4 in atherosclerosis promotion
Authors: E Igel, A Haller, PR Wolfkiel, M Orr-Asman, A Jaeschke, DY Hui
The Journal of Biological Chemistry, 2021-08-21;0(0):101106.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors
Authors: Y Zhou, J Hann, V Schenten, S Plançon, JL Bueb, F Tolle, S Bréchard
International Journal of Molecular Sciences, 2021-08-17;22(16):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Propofol Ameliorates Microglia Activation by Targeting MicroRNA-221/222-IRF2 Axis
Authors: X Xiao, Y Hou, W Yu, S Qi
Journal of Immunology Research, 2021-08-10;2021(0):3101146.
Species: Mouse
Sample Types: Cell Culture Supernates
-
DNA-Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice
Authors: Y Koga, A Sotokawauc, Y Higashimot, Y Nishino, N Hashizume, T Kakuma, J Akiba, Y Tanaka, T Matsui, M Yagi, SI Yamagishi
Oxidative Medicine and Cellular Longevity, 2021-08-07;2021(0):9932311.
Species: Mouse
Sample Types: Serum
-
Aging and neuroinflammation: Changes in immune cell responses, axon integrity, and motor function in a viral model of progressive multiple sclerosis
Authors: L Mestre, G Alonso, A Feliú, M Mecha, C Martín, LM Villar, C Guaza
Aging Cell, 2021-08-06;0(0):e13440.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Selective NF-kappaB inducing kinase inhibitor attenuates the onset of chronic periodontitis
Authors: J Wang, S Wu, Z Li, L Liu, Y Pang, J Wei
The international journal of biochemistry & cell biology, 2021-08-05;0(0):106052.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Pirfenidone ameliorates silica-induced lung inflammation and fibrosis in mice by inhibiting the secretion of interleukin-17A
Authors: ZJ Cao, Y Liu, Z Zhang, PR Yang, ZG Li, MY Song, XM Qi, ZF Han, JL Pang, BC Li, XR Zhang, HP Dai, J Wang, C Wang
Acta pharmacologica Sinica, 2021-07-27;0(0):.
Species: Mouse
Sample Types: BALF
-
Pore-forming alpha-hemolysin efficiently improves the immunogenicity and protective efficacy of protein antigens
Authors: JT Zou, HM Jing, Y Yuan, LH Lei, ZF Chen, Q Gou, QS Xiong, XL Zhang, Z Zhao, XK Zhang, H Zeng, QM Zou, JY Zhang
PloS Pathogens, 2021-07-21;17(7):e1009752.
Species: Mouse
Sample Types: Tissue Homogenates
-
Gramine promotes functional recovery after spinal cord injury via ameliorating microglia activation
Authors: X Lu, F Lu, J Yu, X Xue, H Jiang, L Jiang, Y Yang
Journal of Cellular and Molecular Medicine, 2021-07-19;25(16):7980-7992.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Network Pharmacological Analysis and Experimental Validation of the Mechanisms of Action of Si-Ni-San Against Liver Fibrosis
Authors: S Wang, C Tang, H Zhao, P Shen, C Lin, Y Zhu, D Han
Frontiers in Pharmacology, 2021-07-01;12(0):656115.
Species: Mouse
Sample Types: Serum
-
Kakonein restores diabetes-induced endothelial junction dysfunction via promoting autophagy-mediated NLRP3 inflammasome degradation
Authors: D Lian, J Liu, R Han, J Jin, L Zhu, Y Zhang, Y Huang, X Wang, S Xian, Y Chen
Journal of Cellular and Molecular Medicine, 2021-06-27;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Alterations in circulating extracellular vesicles underlie social stress-induced behaviors in mice
Authors: S Sakamoto, D Mallah, DJ Medeiros, E Dohi, T Imai, IV Rose, K Matoba, X Zhu, A Kamiya, SI Kano
FEBS Open Bio, 2021-06-24;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Testosterone strongly enhances azoxymethane/dextran sulfate sodium-induced colorectal cancer development in C57BL/6 mice
Authors: CH Song, N Kim, RH Nam, SI Choi, JE Yu, H Nho, E Shin, HN Lee, YJ Surh
American journal of cancer research, 2021-06-15;11(6):3145-3162.
Species: Mouse
Sample Types: Tissue Homogenates
-
LncRNA FENDRR Expression Correlates with Tumor Immunogenicity
Authors: MC Munteanu, SN Sethuraman, MP Singh, J Malayer, A Ranjan
Genes, 2021-06-10;12(6):.
Species: Mouse
Sample Types: Tumor Lysate
-
Baicalin relieves Mycoplasma�pneumoniae infection?induced lung injury through regulating microRNA?221 to inhibit the TLR4/NF?&kappaB signaling pathway
Authors: H Zhang, X Li, J Wang, Q Cheng, Y Shang, G Wang
Molecular Medicine Reports, 2021-06-10;24(2):.
Species: Mouse
Sample Types: BALF
-
The Fungal Metabolite (+)-Terrein Abrogates Ovariectomy-Induced Bone Loss and Receptor Activator of Nuclear Factor-&kappaB Ligand-Induced Osteoclastogenesis by Suppressing Protein Kinase-C &alpha/&betaII Phosphorylation
Authors: K Sakaida, K Omori, M Nakayama, H Mandai, S Nakagawa, H Sako, C Kamei, S Yamamoto, H Kobayashi, S Ishii, M Ono, S Ibaragi, K Yamashiro, T Yamamoto, S Suga, S Takashiba
Frontiers in Pharmacology, 2021-06-08;12(0):674366.
Species: Mouse
Sample Types: Serum
-
Ginsenoside Rb1 prevents deoxynivalenol-induced immune injury via alleviating oxidative stress and apoptosis in mice
Authors: SA Rajput, A Shaukat, IR Rajput, AA Kamboh, Z Iqbal, M Saeed, RW Akhtar, SAH Shah, MA Raza, A El Askary, MM Abdel-Daim, ZM Mohammedsa, RM Aljarai, MO Alamoudi, MA Alotaibi
Ecotoxicology and environmental safety, 2021-05-28;220(0):112333.
Species: Mouse
Sample Types: Serum
-
Anti?inflammatory effect of Chrysanthemum zawadskii, peppermint, Glycyrrhiza glabra herbal mixture in�lipopolysaccharide?stimulated RAW264.7 macrophages
Authors: BO Cho, JY Shin, HJ Kang, JH Park, S Hao, F Wang, SI Jang
Molecular Medicine Reports, 2021-05-26;24(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
V&gamma4 T cell-derived IL-17A is essential for amplification of inflammatory cascades in ischemic brain tissue after stroke
Authors: L Lu, Y Wang, L Zhou, Y Li, X Zhang, X Hu, S Shi, W He
International immunopharmacology, 2021-05-24;96(0):107678.
Species: Mouse
Sample Types: Tissue Homogenates
-
Hydrogen sulfide attenuates renal I/R?induced activation of the inflammatory response and apoptosis via regulating Nrf2?mediated NLRP3 signaling pathway inhibition
Authors: Y Su, Y Wang, M Liu, H Chen
Molecular Medicine Reports, 2021-05-20;24(1):.
Species: Mouse
Sample Types: Serum
-
IL-1&beta Impaired Diabetic Wound Healing by Regulating MMP-2 and MMP-9 through the p38 Pathway
Authors: J Dai, J Shen, Y Chai, H Chen
Mediators of Inflammation, 2021-05-18;2021(0):6645766.
Species: Mouse
Sample Types: Serum
-
Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection
Authors: T Lin, D Quellier, J Lamb, T Voisin, P Baral, F Bock, A Schönberg, R Mirchev, G Pier, I Chiu, M Gadjeva
PloS Pathogens, 2021-05-06;17(5):e1009557.
Species: Mouse
Sample Types: Tissue Homogenates
-
Augmenting ATG14 alleviates atherosclerosis and inhibits inflammation via promotion of autophagosome-lysosome fusion in macrophages
Authors: H Zhang, S Ge, B Ni, K He, P Zhu, X Wu, Y Shao
Autophagy, 2021-05-04;0(0):.
Species: Mouse
Sample Types: Serum
-
Neuromodulatory effect of interleukin 1&beta in the dorsal raphe nucleus on individual differences in aggression
Authors: A Takahashi, H Aleyasin, MA Stavarache, L Li, F Cathomas, LF Parise, HY Lin, CJ Burnett, A Aubry, ME Flanigan, A Brancato, C Menard, ML Pfau, V Kana, J Wang, GE Hodes, T Sasaki, MG Kaplitt, S Ogawa, BS McEwen, SJ Russo
Molecular Psychiatry, 2021-04-30;0(0):.
Species: Mouse
Sample Types: Serum
-
Effects of S1PR2 antagonist on blood pressure and angiogenesis imbalance in preeclampsia rats
Authors: T Zhang, D Guo, W Zheng, Q Dai
Molecular Medicine Reports, 2021-04-21;23(6):.
Species: Rat
Sample Types: Serum
-
Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age
Authors: N McGarry, CL Murray, S Garvey, A Wilkinson, L Tortorelli, L Ryan, L Hayden, D Healy, EW Griffin, E Hennessy, M Arumugam, DT Skelly, KJ Mitchell, C Cunningham
Brain, Behavior, and Immunity, 2021-04-21;95(0):413-428.
Species: Mouse
Sample Types: Plasma
-
A derivative of vitamin B3 applied several days after exposure reduces lethality of severely irradiated mice
Authors: A Cheda, EM Nowosielsk, J Gebicki, A Marcinek, S Chlopicki, MK Janiak
Scientific Reports, 2021-04-12;11(1):7922.
Species: Mouse
Sample Types: Serum
-
Type 1 interferon mediates chronic stress-induced neuroinflammation and behavioral deficits via complement component 3-dependent pathway
Authors: A Tripathi, C Whitehead, K Surrao, A Pillai, A Madeshiya, Y Li, H Khodadadi, AO Ahmed, G Turecki, B Baban, A Pillai
Molecular Psychiatry, 2021-04-08;0(0):.
Species: Mouse
Sample Types: Serum
-
Evaluation of the neurotoxic effects of engineered nanomaterials in C57BL/6J mice in 28-day oral exposure studies
Authors: A Sofranko, T Wahle, HJ Heusinkvel, B Stahlmecke, M Dronov, D Pijnenburg, R Hilhorst, K Lamann, C Albrecht, RPF Schins
Neurotoxicology, 2021-03-23;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Exosomal circEhmt1 Released from Hypoxia-Pretreated Pericytes Regulates High Glucose-Induced Microvascular Dysfunction via the NFIA/NLRP3 Pathway
Authors: L Ye, H Guo, Y Wang, Y Peng, Y Zhang, S Li, M Yang, L Wang
Oxidative Medicine and Cellular Longevity, 2021-03-18;2021(0):8833098.
Species: Mouse
Sample Types: Cell Culture Supernates
-
ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation
Authors: T Zhang, H Tsutsuki, W Islam, K Ono, K Takeda, T Akaike, T Sawa
Redox Biology, 2021-03-10;41(0):101930.
Species: Mouse
Sample Types: Cell Culture Supernates
-
GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy
Authors: Y Li, Y Yuan, ZX Huang, H Chen, R Lan, Z Wang, K Lai, H Chen, Z Chen, Z Zou, HB Ma, HY Lan, TW Mak, Y Xu
Cell Death and Differentiation, 2021-03-04;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Juglanin protects against high fat diet-induced renal injury by suppressing inflammation and dyslipidemia via regulating NF-&kappaB/HDAC3 signaling
Authors: Q Li, C Ge, J Tan, Y Sun, Q Kuang, X Dai, S Zhong, C Yi, LF Hu, DS Lou, M Xu
International immunopharmacology, 2021-03-02;95(0):107340.
Species: Mouse
Sample Types: Serum
-
Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life
Authors: MG Granja, LP Alves, M Leardini-T, ME Saul, LC Bortoni, FM de Moraes, EC Ferreira, BPT de Moraes, VZ da Silva, AFR Dos Santos, AR Silva, CF Gonçalves-, V Bambini-Ju, AS Weyrich, MT Rondina, GA Zimmerman, HC de Castro-
Journal of Neuroinflammation, 2021-02-25;18(1):60.
Species: Mouse
Sample Types: Tissue Homogenates
-
Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer's disease transgenic mouse model
Authors: JKY Lau, M Tian, Y Shen, SF Lau, WY Fu, AKY Fu, NY Ip
Scientific Reports, 2021-02-23;11(1):4359.
Species: Mouse
Sample Types: Tissue Homogenates
-
Microglia-derived interleukin-10 accelerates post-intracerebral hemorrhage hematoma clearance by regulating CD36
Authors: Q Li, X Lan, X Han, F Durham, J Wan, A Weiland, RC Koehler, J Wang
Brain, Behavior, and Immunity, 2021-02-13;94(0):437-457.
Species: Mouse
Sample Types: Tissue Homogenates
-
Alpha-1 antitrypsin deficiency impairs lung antibacterial immunity in mice
Authors: L Ostermann, R Maus, J Stolper, L Schütte, K Katsarou, S Tumpara, A Pich, C Mueller, S Janciauski, T Welte, UA Maus
JCI Insight, 2021-02-08;6(3):.
Species: Mouse
Sample Types: BALF
-
SARS-CoV-2 spike protein S1 subunit induces pro-inflammatory responses via toll-like receptor 4 signaling in murine and human macrophages
Authors: K Shirato, T Kizaki
Heliyon, 2021-02-02;7(2):e06187.
Species: Human, Mouse
Sample Types: Cell Culture Supernates
-
Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum
Authors: L Liu, CZ Aron, CM Grable, A Robles, X Liu, Y Liu, NY Fatheree, JM Rhoads, JL Alcorn
Scientific Reports, 2021-01-28;11(1):2593.
Species: Mouse
Sample Types: Tissue Homogenates
-
Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner
Authors: W Zhang, G Yin, H Zhao, H Ling, Z Xie, C Xiao, Y Chen, Y Lin, T Jiang, S Jin, J Wang, X Yang
Cell Death & Disease, 2021-01-20;12(1):102.
Species: Mouse
Sample Types: Serum
-
A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette-Gu�rin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-&alpha
Authors: K Tajiri, K Imanaka-Yo, Y Tsujimura, K Matsuo, M Hiroe, K Aonuma, M Ieda, Y Yasutomi
International Journal of Molecular Sciences, 2021-01-14;22(2):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Complement-5 inhibition deters progression of fulminant hepatitis to acute liver failure in murine models
Authors: J Kusakabe, K Hata, H Miyauchi, T Tajima, Y Wang, I Tamaki, J Kawasoe, Y Okamura, X Zhao, T Okamoto, T Tsuruyama, S Uemoto
Cellular and Molecular Gastroenterology and Hepatology, 2021-01-12;0(0):.
Species: Mouse
Sample Types: Serum
-
Fisetin protects against high fat diet-induced nephropathy by inhibiting inflammation and oxidative stress via the blockage of iRhom2/NF-&kappaB signaling
Authors: G Chenxu, D Xianling, K Qin, H Linfeng, S Yan, X Mingxin, T Jun, X Minxuan
International immunopharmacology, 2021-01-08;92(0):107353.
Species: Mouse
Sample Types: Serum
-
Psoralidin, a major component of Psoraleae Fructus, induces inflammasome activation and idiosyncratic liver injury
Authors: Y Wang, G Xu, Z Wang, R Li, X Zhan, H Liu, Q Qin, W Li, X Wang, M Zhang, J Tang, Z Bai, X Xiao
International immunopharmacology, 2021-01-07;92(0):107352.
Species: Mouse
Sample Types: Serum
-
CX3CR1 is a prerequisite for the development of cardiac hypertrophy and left ventricular dysfunction in mice upon transverse aortic constriction
Authors: CK Weisheit, JL Kleiner, MB Rodrigo, ST Niepmann, S Zimmer, GD Duerr, M Coburn, C Kurts, S Frede, L Eichhorn
PLoS ONE, 2021-01-07;16(1):e0243788.
Species: Mouse
Sample Types: Tissue Homogenates
-
KLF4 down-regulation resulting from TLR4 promotion of ERK1/2 phosphorylation underpins inflammatory response in sepsis
Authors: C Li, L Yu, C Mai, T Mu, Y Zeng
Journal of Cellular and Molecular Medicine, 2020-12-27;0(0):.
Species: Mouse
Sample Types: Serum
-
The Role of Soluble Uric Acid in Modulating Autophagy Flux and Inflammasome Activation during Bacterial Infection in Macrophages
Authors: D Al-Awad, N Al-Emadi, M Abu-Madi, AA Al-Thani, SM Zughaier
Biomedicines, 2020-12-12;8(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Astrocyte-derived exosomes carry microRNA-17-5p to protect neonatal rats from hypoxic-ischemic brain damage via inhibiting BNIP-2 expression
Authors: L Du, Y Jiang, Y Sun
Neurotoxicology, 2020-12-10;83(0):28-39.
Species: Mouse
Sample Types: Tissue Homogenates
-
Extracellular microvesicles that originated adipose tissue derived mesenchymal stem cells have the potential ability to improve rheumatoid arthritis on mice
Authors: K Tsujimaru, M Takanashi, K Sudo, A Ishikawa, S Mineo, S Ueda, K Kumagai, M Kuroda
Regenerative Therapy, 2020-12-09;15(0):305-311.
Species: Mouse
Sample Types: Serum
-
Infusion of blood from mice displaying cerebral amyloidosis accelerates amyloid pathology in animal models of Alzheimer's disease
Authors: R Morales, C Duran-Anio, J Bravo-Aleg, LD Estrada, M Shahnawaz, PP Hu, C Kramm, D Morales-Sc, A Urayama, C Soto
Acta neuropathologica communications, 2020-12-07;8(1):213.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1&alpha-NF-&kappaB Crosstalk In Vitro and In Vivo
Authors: SN Chang, DK Dey, ST Oh, WH Kong, KH Cho, EM Al-Olayan, BS Hwang, SC Kang, JG Park
International Journal of Molecular Sciences, 2020-12-04;21(23):.
Species: Mouse
Sample Types: Tissue Culture Supernates
-
An allosteric interleukin-1 receptor modulator mitigates inflammation and photoreceptor toxicity in a model of retinal degeneration
Authors: R Dabouz, CWH Cheng, P Abram, S Omri, G Cagnone, KV Sawmy, JS Joyal, M Desjarlais, D Olson, AG Weil, W Lubell, JC Rivera, S Chemtob
J Neuroinflammation, 2020-11-27;17(1):359.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling
Authors: Q Xu, Y Fan, JJ Loor, Y Liang, X Sun, H Jia, C Zhao, C Xu
Frontiers in Pharmacology, 2020-11-13;11(0):601716.
Species: Mouse
Sample Types: Serum
-
Dexmedetomidine attenuates sevoflurane?induced neurocognitive impairment through α2?adrenoceptors
Authors: Y Zhang, M Li, E Cui, H Zhang, X Zhu, J Zhou, M Yan, J Sun
Mol Med Rep, 2020-11-12;23(1):.
Species: Mouse
Sample Types: Tissue Culture Supernates
-
Alleviation of Ulcerative Colitis Potentially through th1/th2 Cytokine Balance by a Mixture of Rg3-enriched Korean Red Ginseng Extract and Persicaria tinctoria
Authors: E Saba, YY Lee, MH Rhee, SD Kim
Molecules, 2020-11-10;25(22):.
Species: Mouse
Sample Types: Plasma
-
Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15
Authors: Z Zhang, Y Wang, Y Shan, R Zhou, W Yin
Sci Rep, 2020-11-06;10(1):19272.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons
Authors: DF Silva, E Candeias, AR Esteves, JD Magalhães, IL Ferreira, D Nunes-Cost, AC Rego, N Empadinhas, SM Cardoso
J Neuroinflammation, 2020-11-05;17(1):332.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity
Authors: JJ Fuster, MA Zuriaga, V Zorita, S MacLauchla, MN Polackal, V Viana-Huet, A Ferrer-Pér, N Matesanz, A Herrero-Ce, S Sano, MA Cooper, H González-N, K Walsh
Cell Rep, 2020-10-27;33(4):108326.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CSF1R signaling is a regulator of pathogenesis in progressive MS
Authors: N Hagan, JL Kane, D Grover, L Woodworth, C Madore, J Saleh, J Sancho, J Liu, Y Li, J Proto, M Zelic, A Mahan, M Kothe, AA Scholte, M Fitzgerald, B Gisevius, A Haghikia, O Butovsky, D Ofengeim
Cell Death Dis, 2020-10-23;11(10):904.
Species: Mouse
Sample Types: Cell Culture Supernates
-
LPS-Induced Acute Kidney Injury Is Mediated by Nox4-SH3YL1
Authors: JY Yoo, DR Cha, B Kim, EJ An, SR Lee, JJ Cha, YS Kang, JY Ghee, JY Han, YS Bae
Cell Rep, 2020-10-20;33(3):108245.
Species: Mouse
Sample Types: Serum
-
Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling
Authors: B Zhou, J Liu, L Zeng, S Zhu, H Wang, TR Billiar, G Kroemer, DJ Klionsky, HJ Zeh, J Jiang, D Tang, R Kang
Nat Microbiol, 2020-10-19;0(0):.
Species: Mouse
Sample Types: Cell Lysates
-
Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-&beta1 up-regulate miR-132 and promote mouse M2 macrophage polarization
Authors: Y Wang, B Han, Y Wang, C Wang, H Zhang, J Xue, X Wang, T Niu, Z Niu, Y Chen
J. Cell. Mol. Med., 2020-09-23;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Resveratrol alleviates intestinal mucosal barrier dysfunction in dextran sulfate sodium-induced colitis mice by enhancing autophagy
Authors: HH Pan, XX Zhou, YY Ma, WS Pan, F Zhao, MS Yu, JQ Liu
World J. Gastroenterol., 2020-09-07;26(33):4945-4959.
Species: Mouse
Sample Types: Plasma
-
Alcohol consumption promotes colorectal cancer by altering intestinal permeability
Authors: XY Diao, T Peng, FG Kong, JG Huang, S Han, YS Shang, H Liu
Eur Rev Med Pharmacol Sci, 2020-09-01;24(18):9370-9377.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Positive Effects of Preventive Nutrition Supplement on Anticancer Radiotherapy in Lung Cancer Bearing Mice
Authors: YM Liu, TH Wu, YH Chiu, H Wang, TL Li, S Hsia, YL Chan, CJ Wu
Cancers (Basel), 2020-08-28;12(9):.
Species: Mouse
Sample Types: Serum
-
The alpha2 Na+/K+-ATPase isoform mediates LPS-induced neuroinflammation
Authors: JA Leite, TJ Isaksen, A Heuck, C Scavone, K Lykke-Hart
Sci Rep, 2020-08-25;10(1):14180.
Species: Mouse
Sample Types: Serum
-
Myeloid FBW7 deficiency disrupts redox homeostasis and aggravates dietary-induced insulin resistance
Authors: C Wang, Y Chao, W Xu, Z Liu, H Wang, K Huang
Redox Biol, 2020-08-15;37(0):101688.
Species: Mouse, Transgenic Mouse
Sample Types: Plasma
-
Preconditioning mesenchymal stromal cells with flagellin enhances the anti?inflammatory ability of their secretome against lipopolysaccharide?induced acute lung injury
Authors: R Li, Y Li, X Dong
Molecular Medicine Reports, 2020-07-28;0(0):.
Species: Human, Mouse
Sample Types: BALF
-
Roseburia�intestinalis?derived flagellin ameliorates colitis by targeting miR?223?3p?mediated activation of NLRP3 inflammasome and pyroptosis
Authors: X Wu, S Pan, W Luo, Z Shen, X Meng, M Xiao, B Tan, K Nie, T Tong, X Wang
Mol Med Rep, 2020-07-23;0(0):.
Species: Mouse
Sample Types: Serum
-
Nrf2 mitigates prolonged PM2.5 exposure-triggered liver inflammation by positively regulating SIKE activity: Protection by Juglanin
Authors: C Ge, J Tan, S Zhong, L Lai, G Chen, J Zhao, C Yi, L Wang, L Zhou, T Tang, Q Yang, D Lou, Q Li, Y Wu, L Hu, G Kuang, X Liu, B Wang, M Xu
Redox Biol, 2020-07-17;36(0):101645.
Species: Mouse, Transgenic Mouse
Sample Types: Serum, Tissue Homogenates
-
Protective effects of catalpol on mitochondria of hepatocytes in cholestatic liver injury
Authors: X Gao, J Xu, H Liu
Mol Med Rep, 2020-07-13;22(3):2424-2432.
Species: Mouse
Sample Types: Serum
-
Fisetin alleviates sepsis-induced multiple organ dysfunction in mice via inhibiting p38 MAPK/MK2 signaling
Authors: HF Zhang, HB Zhang, XP Wu, YL Guo, WD Cheng, F Qian
Acta Pharmacol. Sin., 2020-07-13;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Combined administration of SHP2 inhibitor SHP099 and the &alpha7nAChR agonist PNU282987 protect mice against DSS?induced colitis
Authors: J Xiao, G Zhang, S Gao, J Shen, H Feng, Z He, C Xu
Mol Med Rep, 2020-07-10;22(3):2235-2244.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis
Authors: WC Chen, NJ Chen, HP Chen, WK Yu, VY Su, H Chen, HH Wu, KY Yang
Int J Mol Sci, 2020-07-02;21(13):.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-1beta suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury
Authors: S Xiong, Z Hong, LS Huang, Y Tsukasaki, S Nepal, A Di, M Zhong, W Wu, Z Ye, X Gao, GN Rao, D Mehta, J Rehman, AB Malik
J. Clin. Invest., 2020-07-01;130(7):3684-3698.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Apamin Suppresses LPS-Induced Neuroinflammatory Responses by Regulating SK Channels and TLR4-Mediated Signaling Pathways
Authors: J Park, KM Jang, KK Park
Int J Mol Sci, 2020-06-17;21(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A Novel Peptide Oligomer of Bacitracin Induces M1 Macrophage Polarization by Facilitating Ca2+ Influx
Authors: SY Ji, H Lee, H Hwangbo, SH Hong, HJ Cha, C Park, DH Kim, GY Kim, S Kim, HS Kim, JC Yoo, YH Choi
Nutrients, 2020-05-29;12(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by &beta-Glucan
Authors: ST Keating, L Groh, CDCC van der He, H Rodriguez, JC Dos Santos, S Fanucchi, J Okabe, H Kaipananic, JH van Puffel, L Helder, MP Noz, V Matzaraki, Y Li, LCJ de Bree, VACM Koeken, SJCFM Moorlag, VP Mourits, J Domínguez-, M Oosting, EP Bulthuis, WJH Koopman, M Mhlanga, A El-Osta, LAB Joosten, MG Netea, NP Riksen
Cell Rep, 2020-04-21;31(3):107548.
Species: Mouse
Sample Types: Plasma
-
Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases
Authors: W Shi, G Xu, X Zhan, Y Gao, Z Wang, S Fu, N Qin, X Hou, Y Ai, C Wang, T He, H Liu, Y Chen, Y Liu, J Wang, M Niu, Y Guo, X Xiao, Z Bai
Cell Death Dis, 2020-04-20;11(4):252.
Species: Mouse
Sample Types: Serum
-
Maternal high-fat diet exaggerates diet-induced insulin resistance in adult offspring by enhancing inflammasome activation through noncanonical pathway of caspase-11
Authors: N Wada, H Yamada, S Motoyama, M Saburi, T Sugimoto, H Kubota, D Miyawaki, N Wakana, D Kami, T Ogata, S Matoba
Mol Metab, 2020-04-06;37(0):100988.
Species: Mouse
Sample Types: Serum
-
Monascin ameliorate inflammation in the lipopolysaccharide-induced BV-2 microglial cells via suppressing the NF-kappaB/p65 pathway
Authors: YX Shi, WS Chen
Iran J Basic Med Sci, 2020-04-01;23(4):461-468.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Octominin Inhibits LPS-Induced Chemokine and Pro-inflammatory Cytokine Secretion from RAW 264.7 Macrophages via Blocking TLRs/NF-kappaB Signal Transduction
Authors: KKA Sanjeewa, DP Nagahawatt, HW Yang, JY Oh, TU Jayawarden, YJ Jeon, M De Zoysa, I Whang, B Ryu
Biomolecules, 2020-03-27;10(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci
Authors: A Famà, A Midiri, G Mancuso, C Biondo, G Lentini, R Galbo, MM Giardina, GV De Gaetano, L Romeo, G Teti, C Beninati
MBio, 2020-03-24;11(2):.
Species: Mouse
Sample Types: Tissue Lysates
-
Activation of ASC Inflammasome Driven by TLR4 Contributes to Host Immunity against Rickettsial Infection
Authors: C Rumfield, I Hyseni, JW McBride, DH Walker, R Fang
Infect. Immun., 2020-03-23;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Attenuation of noisy environment-induced neuroinflammation and dysfunction of learning and memory by minocycline during perioperative period in mice
Authors: F Lin, Y Zheng, L Pan, Z Zuo
Brain Res. Bull., 2020-03-21;159(0):16-24.
Species: Mouse
Sample Types: Tissue Homogenates
-
Nrf2 deficiency aggravates PM2.5-induced cardiomyopathy by enhancing oxidative stress, fibrosis and inflammation via RIPK3-regulated mitochondrial disorder
Authors: C Ge, L Hu, D Lou, Q Li, J Feng, Y Wu, J Tan, M Xu
Aging (Albany NY), 2020-03-17;12(6):4836-4865.
Species: Mouse
Sample Types: Serum
-
Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury
Authors: FQ Kong, SJ Zhao, P Sun, H Liu, J Jie, T Xu, AD Xu, YQ Yang, Y Zhu, J Chen, Z Zhou, DF Qian, CJ Gu, Q Chen, GY Yin, HW Zhang, J Fan
J Neuroinflammation, 2020-02-17;17(1):62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Effect of HBx on inflammation and mitochondrial oxidative stress in mouse hepatocytes
Authors: LR Ling, DH Zheng, ZY Zhang, WH Xie, YH Huang, ZX Chen, XZ Wang, D Li
Oncol Lett, 2020-02-17;19(4):2861-2869.
-
Development of an IL-17A DNA Vaccine to Treat Systemic Lupus Erythematosus in Mice
Authors: H Koriyama, Y Ikeda, H Nakagami, M Shimamura, S Yoshida, H Rakugi, R Morishita
Vaccines (Basel), 2020-02-12;8(1):.
Species: Mouse
Sample Types: Serum
-
Hydrogen Sulfide Attenuates Particulate Matter-Induced Emphysema and Airway Inflammation Through Nrf2-Dependent Manner
Authors: G Jia, S Yu, W Sun, J Yang, Y Wang, Y Qi, Y Chen
Front Pharmacol, 2020-02-07;11(0):29.
Species: Mouse
Sample Types: BALF
-
Antagonizing binding of cell cycle and apoptosis regulatory protein 1 (CARP-1) to the NEMO/IKKgamma protein enhances the anticancer effect of chemotherapy
Authors: J Venkatesh, SC Sekhar, VT Cheriyan, M Muthu, P Meister, E Levi, S Dzinic, JW Gauld, LA Polin, AK Rishi
J. Biol. Chem., 2020-02-04;295(11):3532-3552.
Species: Mouse
Sample Types: Serum
-
Ubiquitin fold modifier 1 activates NF-kappaB pathway by down-regulating LZAP expression in the macrophage of diabetic mouse model
Authors: X Hu, H Zhang, Y Song, L Zhuang, Q Yang, M Pan, F Chen
Biosci. Rep., 2020-01-31;40(1):.
Species: Mouse
Sample Types: Serum
-
Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1&beta Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration
Authors: Y Gao, D Tu, R Yang, CH Chu, JS Hong, HM Gao
Int J Mol Sci, 2020-01-11;21(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Tumor Cell-Derived IL1&beta Promotes Desmoplasia and Immune Suppression in Pancreatic Cancer
Authors: S Das, B Shapiro, EA Vucic, S Vogt, D Bar-Sagi
Cancer Res., 2020-01-08;80(5):1088-1101.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice
Authors: C Quach, Y Song, H Guo, S Li, H Maazi, M Fung, N Sands, D O'Connell, S Restrepo-V, B Chai, D Nemecio, V Punj, O Akbari, GE Idos, SM Mumenthale, N Wu, SE Martin, A Hagiya, J Hicks, H Cui, C Liang
Nat Commun, 2019-12-12;10(1):5681.
Species: Mouse
Sample Types: Serum
-
Notoginsenoside R1 suppresses miR-301a via NF-kappaB pathway in lipopolysaccharide-treated ATDC5 cells
Authors: Y Dong, X Yan, X Yang, C Yu, Y Deng, X Song, L Zhang
Exp. Mol. Pathol., 2019-12-11;112(0):104355.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Increased Soluble Epoxide Hydrolase in Human Gestational Tissues from Pregnancies Complicated by Acute Chorioamnionitis
Authors: TH Hung, SF Chen, CH Wu, CC Kao, CP Wu
Mediators Inflamm., 2019-12-05;2019(0):8687120.
Species: Mouse
Sample Types: Tissue Homogenates
-
Oral flavonoid fisetin treatment protects against prolonged high-fat-diet-induced cardiac dysfunction by regulation of multicombined signaling
Authors: LF Hu, J Feng, X Dai, Y Sun, M Xiong, L Lai, S Zhong, C Yi, G Chen, H Li, Q Yang, Q Kuang, T Long, J Zhan, T Tang, C Ge, J Tan, M Xu
J. Nutr. Biochem., 2019-11-25;77(0):108253.
Species: Mouse
Sample Types: Serum
-
Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice
Authors: K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo
Dis Model Mech, 2019-11-12;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Benzydamine inhibits osteoclast differentiation and bone resorption via down-regulation of interleukin-1 &beta expression
Authors: HS Son, J Lee, HI Lee, N Kim, YJ Jo, GR Lee, SE Hong, M Kwon, NY Kim, HJ Kim, JH Park, SY Lee, W Jeong
Acta Pharm Sin B, 2019-11-08;10(3):462-474.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Autophagy regulates the therapeutic potential of adipose-derived stem cells in LPS-induced pulmonary microvascular barrier damage
Authors: C Li, J Pan, L Ye, H Xu, B Wang, H Xu, L Xu, T Hou, D Zhang
Cell Death Dis, 2019-10-23;10(11):804.
Species: Mouse
Sample Types: BALF
-
Downregulation of RalGTPase-activating protein promotes colitis-associated cancer via NLRP3 inflammasome activation
Authors: T Iida, Daisuke Hi, N Minami, M Matsuura, K Wagatsuma, K Kawakami, K Nagaishi, M Nojima, H Ikeuchi, S Hirota, R Shirakawa, H Horiuchi, H Nakase
Cell Mol Gastroenterol Hepatol, 2019-10-15;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis
Authors: N Ershaid, Y Sharon, H Doron, Y Raz, O Shani, N Cohen, L Monteran, L Leider-Tre, A Ben-Shmuel, M Yassin, M Gerlic, A Ben-Baruch, M Pasmanik-C, R Apte, N Erez
Nat Commun, 2019-09-26;10(1):4375.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells
Authors: P Wang, X Qi, G Xu, J Liu, J Guo, X Li, X Ma, H Sun
Aging (Albany NY), 2019-09-26;11(18):7402-7415.
Species: Mouse
Sample Types: Tissue Homogenates
-
Gestational oxidative stress protects against adult obesity and insulin resistance
Authors: LG Dimova, S Battista, T Plösch, RA Kampen, F Liu, RN Verkaik-Sc, D Pratico, HJ Verkade, UJF Tietge
Redox Biol, 2019-09-17;28(0):101329.
Species: Mouse
Sample Types: Plasma
-
Fucoxanthin, a Marine Xanthophyll Isolated From Conticribra weissflogii ND-8: Preventive Anti-Inflammatory Effect in a Mouse Model of Sepsis
Authors: J Su, K Guo, M Huang, Y Liu, J Zhang, L Sun, D Li, KL Pang, G Wang, L Chen, Z Liu, Y Chen, Q Chen, L Huang
Front Pharmacol, 2019-08-28;10(0):906.
Species: Mouse
Sample Types: Serum
-
Macrophage migration inhibitory factor enhances influenza-associated mortality in mice
Authors: CA Smith, DJ Tyrell, UA Kulkarni, S Wood, L Leng, RL Zemans, R Bucala, DR Goldstein
JCI Insight, 2019-07-11;4(13):.
Species: Mouse
Sample Types: BALF
-
Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein
Authors: PAM Cavalcante, N Alenina, A Budu, LC Freitas-Li, T Alves-Silv, JSH Agudelo, F Qadri, NOS Camara, M Bader, RC Araújo
Mediators Inflamm., 2019-07-10;2019(0):9086758.
Species: Mouse
Sample Types: Tissue Lysates
-
Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment
Authors: N Smith, MP Rodero, N Bekaddour, V Bondet, YB Ruiz-Blanc, M Harms, B Mayer, B Badder-Meu, P Quartier, C Bodemer, V Baudouin, Y Dieudonné, F Kirchhoff, E Sanchez Ga, B Charbit, N Leboulange, B Jahrsdörfe, Y Richard, AS Korganow, J Münch, S Nisole, D Duffy, JP Herbeuval
Sci Adv, 2019-07-10;5(7):eaav9019.
Species: Mouse
Sample Types: Serum
-
Immunomodulatory effect of mancozeb, chlorothalonil, and thiophanate methyl pesticides on macrophage cells
Authors: GCC Weis, CE Assmann, FC Cadoná, BDSR Bonadiman, AO Alves, AK Machado, MMMF Duarte, IBM da Cruz, IH Costabeber
Ecotoxicol. Environ. Saf., 2019-07-09;182(0):109420.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury
Authors: Z Ye, L Zhang, R Li, W Dong, S Liu, Z Li, H Liang, L Wang, W Shi, AB Malik, KT Cheng, X Liang
Kidney Blood Press. Res., 2019-06-21;0(0):1-14.
Species: Mouse
Sample Types: Serum
-
Carnosic acid alleviates brain injury through NF?κB?regulated inflammation and Caspase?3?associated apoptosis in high fat?induced mouse models
Authors: Y Liu, Y Zhang, M Hu, YH Li, XH Cao
Mol Med Rep, 2019-05-27;20(1):495-504.
Species: Mouse
Sample Types: Serum
-
cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis
Authors: R Chen, L Zeng, S Zhu, J Liu, HJ Zeh, G Kroemer, H Wang, TR Billiar, J Jiang, D Tang, R Kang
Sci Adv, 2019-05-22;5(5):eaav5562.
Species: Mouse
Sample Types: Serum
-
A Fragment of Apolipoprotein E4 Leads to the Downregulation of a CXorf56 Homologue, a Novel ER-Associated Protein, and Activation of BV2 Microglial Cells
Authors: TB Pollock, JM Mack, RJ Day, NF Isho, RJ Brown, AE Oxford, BE Morrison, EJ Hayden, TT Rohn
Oxid Med Cell Longev, 2019-05-06;2019(0):5123565.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases
Authors: HH Guo, CL Feng, WX Zhang, ZG Luo, HJ Zhang, TT Zhang, C Ma, Y Zhan, R Li, S Wu, Z Abliz, C Li, XL Li, XL Ma, LL Wang, WS Zheng, YX Han, JD Jiang
Nat Commun, 2019-04-30;10(1):1981.
Species: Mouse
Sample Types: Plasma
-
Avicularin Relieves Depressive-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice
Authors: Z Shen, Y Xu, X Jiang, Z Wang, Y Guo, W Pan, J Hou
Med. Sci. Monit., 2019-04-15;25(0):2777-2784.
Species: Mouse
Sample Types: Tissue Homogenates
-
Circulating Cell-Free mtDNA Contributes to AIM2 Inflammasome-Mediated Chronic Inflammation in Patients with Type 2 Diabetes
Authors: JH Bae, SI Jo, SJ Kim, JM Lee, JH Jeong, JS Kang, NJ Cho, SS Kim, EY Lee, JS Moon
Cells, 2019-04-08;8(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Induced Pluripotent Stem Cells Regulate TREM-1 Expression and the p38 MAPK Pathway in Endotoxin-Induced Acute Lung Injury
Authors: VY Su, KY Yang, SH Chiou, NJ Chen, MH Mo, CS Lin, CT Wang
Stem Cells, 2019-02-16;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Melatonin Inhibits Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Cultured Mouse Mammary Tissue
Authors: GM Yu, W Tan
Mediators Inflamm., 2019-02-12;2019(0):8597159.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis
Authors: YH Kwon, H Wang, E Denou, JE Ghia, L Rossi, ME Fontes, SP Bernier, MS Shajib, S Banskota, SM Collins, MG Surette, WI Khan
Cell Mol Gastroenterol Hepatol, 2019-02-01;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion
Authors: Y Xia, N Liu, X Xie, G Bi, H Ba, L Li, J Zhang, X Deng, Y Yao, Z Tang, B Yin, J Wang, K Jiang, Z Li, Y Choi, F Gong, X Cheng, JJ O'Shea, JJ Chae, A Laurence, XP Yang
Autophagy, 2019-01-29;0(0):1-16.
Species: Mouse
Sample Types: Serum
-
Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation
Authors: Y Pan, X Hui, RLC Hoo, D Ye, CYC Chan, T Feng, Y Wang, KSL Lam, A Xu
J. Clin. Invest., 2019-01-22;129(2):834-849.
Species: Mouse
Sample Types: Serum
-
The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome
Authors: MC Trotta, R Maisto, F Guida, S Boccella, L Luongo, C Balta, G D'Amico, H Herman, A Hermenean, C Bucolo, M D'Amico
PLoS ONE, 2019-01-18;14(1):e0211005.
Species: Mouse
Sample Types: Serum
-
Costunolide alleviates HKSA-induced acute lung injury via inhibition of macrophage activation
Authors: YT Chen, Y Du, B Zhao, LX Gan, KK Yu, L Sun, J Wang, F Qian
Acta Pharmacol. Sin., 2019-01-15;0(0):.
Species: Mouse
Sample Types: BALF
-
The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice
Authors: M Okuda, Y Fujita, H Sugimoto
Biol. Pharm. Bull., 2019-01-01;42(10):1694-1706.
Species: Mouse
Sample Types: Tissue Homogenates
-
TRAF3-interacting JNK-activating modulator promotes inflammation by stimulating� translocation of Toll-like receptor 4 to lipid rafts
Authors: Y Li, J Guan, W Wang, C Hou, L Zhou, J Ma, Y Cheng, S Jiao, Z Zhou
J. Biol. Chem., 2018-12-20;0(0):.
Species: Mouse
Sample Types: Serum
-
Pharmacological stimulation of NQO1 decreases NADPH levels and ameliorates acute pancreatitis in mice
Authors: A Shen, HJ Kim, GS Oh, SB Lee, S Lee, A Pandit, D Khadka, S Sharma, SY Kim, SK Choe, SH Yang, EY Cho, H Shim, R Park, TH Kwak, HS So
Cell Death Dis, 2018-12-18;10(1):5.
Species: Mouse
Sample Types: Serum
-
SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain
Authors: A Tyagi, CU Nguyen, T Chong, CR Michel, KS Fritz, N Reisdorph, L Knaub, JEB Reusch, S Pugazhenth
Sci Rep, 2018-12-03;8(1):17547.
Species: Mouse
Sample Types: Plasma
-
A Novel Peroxidase Mimics and Ameliorates Alzheimer's Disease-Related Pathology and Cognitive Decline in Mice
Authors: J Xu, K Wang, Y Yuan, H Li, R Zhang, S Guan, L Wang
Int J Mol Sci, 2018-10-24;19(11):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice.
Authors: Li Z, Luo T, Ning X, Xiong C, Wu A
Neurosci Lett, 2018-09-28;687(0):189-195.
Species: Mouse
Sample Types: Tissue Homogenates
-
?-Synuclein disrupts the anti-inflammatory role of Drd2 via interfering ?-arrestin2-TAB1 interaction in astrocytes
Authors: RH Du, Y Zhou, ML Xia, M Lu, JH Ding, G Hu
J Neuroinflammation, 2018-09-10;15(1):258.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Activation of Bone Marrow-Derived Cells Angiotensin (Ang) II Type 1 Receptor by Ang II Promotes Atherosclerotic Plaque Vulnerability
Authors: M Pellegrin, K Bouzourène, JF Aubert, A Nahimana, MA Duchosal, L Mazzolai
Int J Mol Sci, 2018-09-04;19(9):.
Species: Mouse
Sample Types: Plasma
-
Complement activation contributes to perioperative neurocognitive disorders in mice
Authors: C Xiong, J Liu, D Lin, J Zhang, N Terrando, A Wu
J Neuroinflammation, 2018-09-04;15(1):254.
Species: Mouse
Sample Types: Tissue Homogenates
-
Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury
Authors: Z Gong, J Pan, Q Shen, M Li, Y Peng
J Neuroinflammation, 2018-08-28;15(1):242.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury
Authors: D Li, W Ren, Z Jiang, L Zhu
Mol Med Rep, 2018-08-24;0(0):.
Species: Mouse
Sample Types: BALF
-
Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice
Authors: P Liang, W Shan, Z Zuo
J Neuroinflammation, 2018-08-22;15(1):235.
Species: Mouse
Sample Types: Cell Culture Supernates
-
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress
Authors: X Zhu, MT Nedelcovyc, AG Thomas, Y Hasegawa, A Moreno-Meg, W Coomer, V Vohra, A Saito, G Perez, Y Wu, J Alt, E Prchalova, L Tenora, P Majer, R Rais, C Rojas, BS Slusher, A Kamiya
Neuropsychopharmacology, 2018-08-13;0(0):.
Species: Mouse
Sample Types: Serum
-
Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny
Authors: A Beaudry-Ri, M Nadeau-Val, É Prairie, N Maurice, É Heckel, M Nezhady, S Pundir, A Madaan, A Boudreault, X Hou, C Quiniou, EM Sierra, A Beaulac, G Lodygensky, SA Robertson, J Keelan, K Adams-Wald, DM Olson, JC Rivera, WD Lubell, JS Joyal, JF Bouchard, S Chemtob
Sci Rep, 2018-08-08;8(1):11875.
Species: Mouse
Sample Types: Tissue Homogenates
-
Protective Effects of Nintedanib against Polyhexamethylene Guanidine Phosphate-Induced Lung Fibrosis in Mice
Authors: HY Kim, MS Kim, SH Kim, D Joen, K Lee
Molecules, 2018-08-07;23(8):.
Species: Mouse
Sample Types: Tissue Homogenates
-
The anticancer peptide RT53 induces immunogenic cell death
Authors: E Pasquereau, J Habault, G Kroemer, JL Poyet
PLoS ONE, 2018-08-06;13(8):e0201220.
Species: Mouse
Sample Types: Serum
-
GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain
Authors: S Bang, YK Xie, ZJ Zhang, Z Wang, ZZ Xu, RR Ji
J. Clin. Invest., 2018-07-16;128(8):3568-3582.
Species: Mouse
Sample Types: Tissue Homogenates
-
Myeloid p38? signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis
Authors: C Youssif, M Cubillos-R, M Comalada, E Llonch, C Perna, N Djouder, AR Nebreda
EMBO Mol Med, 2018-07-01;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibition of MicroRNA-23b Attenuates Immunosuppression in Late Sepsis through NIK, TRAF1 and XIAP
Authors: H Zhang, H Li, A Shaikh, Y Caudle, B Yao, D Yin
J. Infect. Dis., 2018-06-20;0(0):.
Species: Mouse
Sample Types: Serum
-
Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms
Authors: DT Skelly, ÉW Griffin, CL Murray, S Harney, C O'Boyle, E Hennessy, MA Dansereau, A Nazmi, L Tortorelli, JN Rawlins, DM Bannerman, C Cunningham
Mol. Psychiatry, 2018-06-06;24(10):1533-1548.
Species: Mouse
Sample Types: Plasma
-
Protective effects of Erigeron breviscapus Hand.- Mazz. (EBHM) extract in retinal neurodegeneration models
Authors: J Zhu, L Chen, Y Qi, J Feng, L Zhu, Y Bai, H Wu
Mol. Vis., 2018-04-25;24(0):315-325.
Species: Rat
Sample Types: Cell Culture Supernates
-
Interleukin-1 receptor antagonist-mediated neuroprotection by umbilical cord-derived mesenchymal stromal cells following transplantation into a rodent stroke model
Authors: SH Oh, C Choi, JE Noh, N Lee, YW Jeong, I Jeon, JM Shin, JH Kim, HJ Kim, JM Lee, HS Kim, OJ Kim, J Song
Exp. Mol. Med., 2018-04-13;50(4):22.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Macrophage-derived IL-1?/NF-?B signaling mediates parenteral nutrition-associated cholestasis
Authors: KC El Kasmi, PM Vue, AL Anderson, MW Devereaux, S Ghosh, N Balasubram, SA Fillon, C Dahrenmoel, A Allawzi, C Woods, S McKenna, CJ Wright, L Johnson, A D'Alessand, JA Reisz, E Nozik-Gray, FJ Suchy, RJ Sokol
Nat Commun, 2018-04-11;9(1):1393.
Species: Mouse
Sample Types: Serum
-
Effect of internal contamination with tritiated water on the neoplastic colonies in the lungs, innate anti-tumour reactions, cytokine profile, and haematopoietic system in radioresistant and radiosensitive mice
Authors: EM Nowosielsk, A Cheda, R Zdanowski, S Lewicki, BR Scott, MK Janiak
Radiat Environ Biophys, 2018-04-06;0(0):.
Species: Mouse
Sample Types: Serum
-
Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS
Authors: HM Song, X Li, YY Liu, WP Lu, ZH Cui, L Zhou, D Yao, HM Zhang
Int. J. Mol. Med., 2018-03-27;0(0):.
Species: Mouse
Sample Types: Serum
-
MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
J. Immunol., 2018-03-21;0(0):.
Species: Mouse
Sample Types: BALF
-
Accelerated inflammation and oxidative stress induced by LPS in acute lung injury: ?nhibition by ST1926
Authors: Z Dong, Y Yuan
Int. J. Mol. Med., 2018-03-19;0(0):.
Species: Mouse
Sample Types: Serum
-
REDD-1 aggravates endotoxin-induced inflammation via atypical NF-?B activation
Authors: DK Lee, JH Kim, J Kim, S Choi, M Park, W Park, S Kim, KS Lee, T Kim, J Jung, YK Choi, KS Ha, MH Won, TR Billiar, YG Kwon, YM Kim
FASEB J., 2018-03-16;0(0):fj201701436R.
Species: Mouse
Sample Types: Serum
-
Juglanin suppresses fibrosis and inflammation response caused by LPS in acute lung injury
Authors: ZW Dong, YF Yuan
Int. J. Mol. Med., 2018-03-09;41(6):3353-3365.
Species: Mouse
Sample Types: Serum
-
Crude extract and fractions from Eugenia uniflora Linn leaves showed anti-inflammatory, antioxidant, and antibacterial activities
Authors: TR Falcão, AA de Araújo, LAL Soares, RT de Moraes, ICF Bezerra, MRA Ferreira, MA de Souza N, MCN Melo, RF de Araújo, ACV de Aguiar, JS de Medeiro, GCB Guerra
BMC Complement Altern Med, 2018-03-09;18(1):84.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Oleanolic acid acetate attenuates polyhexamethylene guanidine phosphate-induced pulmonary inflammation and fibrosis in mice
Authors: MS Kim, JY Han, SH Kim, D Jeon, HY Kim, SW Lee, MC Rho, K Lee
Respir Physiol Neurobiol, 2018-03-02;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation
Authors: S Piao, JW Lee, H Nagar, SB Jung, S Choi, S Kim, I Lee, SM Kim, N Shin, YR Lee, SD Lee, JB Park, K Irani, M Won, GM Hur, BH Jeon, DW Kim, CS Kim
PLoS ONE, 2018-02-23;13(2):e0192693.
Species: Mouse
Sample Types: Plasma
-
An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
Authors: RG Carroll, Z Zas?ona, S Galván-Peñ, EL Koppe, DC Sévin, S Angiari, M Triantafil, K Triantafil, LK Modis, LA O'Neill
J. Biol. Chem., 2018-02-20;293(15):5509-5521.
Species: Mouse
Sample Types: Serum
-
SARM1 deletion restrains NAFLD induced by high fat diet (HFD) through reducing inflammation, oxidative stress and lipid accumulation
Authors: ZG Pan, XS An
Biochem. Biophys. Res. Commun., 2018-02-15;0(0):.
Species: Mouse
Sample Types: Serum
Applications: ELISA Capture -
Immunization with Pseudomonas aeruginosa outer membrane vesicles stimulates protective immunity in mice
Authors: X Zhang, F Yang, J Zou, W Wu, H Jing, Q Gou, H Li, J Gu, Q Zou, J Zhang
Vaccine, 2018-02-14;36(8):1047-1054.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA Capture -
An insight into the role of magnesium in the immunomodulatory properties of mesenchymal stem cells
Authors: F da Silva L, AB da Rocha R, A Hastreiter, A Nogueira-P, E Makiyama, C Colli, RA Fock
J. Nutr. Biochem., 2018-02-13;55(0):200-208.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
Authors: SS Chaurasia, RR Lim, BH Parikh, YS Wey, BB Tun, TY Wong, CD Luu, R Agrawal, A Ghosh, A Mortellaro, E Rackoczy, RR Mohan, VA Barathi
Sci Rep, 2018-02-12;8(1):2847.
Species: Mouse
Sample Types: Tissue Homogenates
-
Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice
Authors: KS Chung, SY Cheon, SS Roh, M Lee, HJ An
Nutrients, 2018-02-12;10(2):.
Species: Mouse
Sample Types: Tissue Culture Supernates
Applications: ELISA Capture -
LncRNA GAS5 Overexpression Reverses LPS-Induced Inflammatory Injury and Apoptosis Through Up-Regulating KLF2 Expression in ATDC5 Chondrocytes
Authors: F Li, J Sun, S Huang, G Su, G Pi
Cell. Physiol. Biochem., 2018-02-09;45(3):1241-1251.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice
Authors: P Doddapatta, M Jain, N Dhanesha, SR Lentz, AK Chauhan
Arterioscler. Thromb. Vasc. Biol., 2018-01-11;0(0):.
Species: Mouse
Sample Types: Plasma
-
Oleocanthal-rich extra-virgin olive oil enhances donepezil effect by reducing amyloid-? load and related toxicity in a mouse model of Alzheimer's disease
Authors: YS Batarseh, A Kaddoumi
J. Nutr. Biochem., 2017-12-27;55(0):113-123.
Species: Mouse
Sample Types: Tissue Homogenates
-
Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKK?/NF-?B signaling in mice
Authors: JM Cho, SM Yun, YH Choi, J Heo, NJ Kim, SH Kim, EH Kim
Oncotarget, 2017-12-12;9(1):866-880.
Species: Mouse
Sample Types: Serum
-
Circulating soluble endoglin modifies the inflammatory response in mice
Authors: L Ruiz-Remol, C Ollauri-Ib, L Pérez-Roqu, E Núñez-Góme, F Pérez-Barr, JM López-Novo, M Pericacho, A Rodríguez-
PLoS ONE, 2017-11-16;12(11):e0188204.
Species: Mouse
Sample Types: Plasma
-
Regulation of Arthritis Severity by the Acid Sphingomyelinase
Authors: N Beckmann, KA Becker, S Walter, JU Becker, M Kramer, G Hessler, S Weber, JR Göthert, K Fassbender, E Gulbins, A Carpinteir
Cell. Physiol. Biochem., 2017-10-16;43(4):1.
Species: Mouse
Sample Types: Tissue Homogenates
-
Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling
Authors: W Lu, D Jia, S An, M Mu, X Qiao, Y Liu, X Li, D Wang
Sci Rep, 2017-08-21;7(1):8402.
Species: Mouse
Sample Types: Plasma
-
Specific calpain inhibition protects kidney against inflammaging
Authors: G Hanouna, L Mesnard, S Vandermeer, J Perez, S Placier, JP Haymann, F Campagne, J Moroch, A Bataille, L Baud, E Letavernie
Sci Rep, 2017-08-14;7(1):8016.
Species: Mouse
Sample Types: Peritoneal Fluid
-
P2X7 receptor antagonism prevents IL-1? release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy
Authors: MG Khalafalla, LT Woods, JM Camden, AA Khan, KH Limesand, MJ Petris, L Erb, GA Weisman
J. Biol. Chem., 2017-08-10;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mitochondrial DNA-enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity
Authors: Y Cai, MJ Xu, EH Koritzinsk, Z Zhou, W Wang, H Cao, PS Yuen, RA Ross, RA Star, S Liangpunsa, B Gao
JCI Insight, 2017-07-20;2(14):.
Species: Mouse
Sample Types: Serum
-
Interleukin-1 receptor in seizure susceptibility after traumatic injury to the pediatric brain
Authors: BD Semple, TJ O'Brien, K Gimlin, DK Wright, S Eun Kim, PM Casillas-E, KM Webster, S Petrou, LJ Noble-Haeu
J. Neurosci., 2017-07-19;0(0):.
Species: Mouse
Sample Types: Serum
-
Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy
Authors: EE To, R Vlahos, R Luong, ML Halls, PC Reading, PT King, C Chan, GR Drummond, CG Sobey, BRS Broughton, MR Starkey, R van der Sl, SR Lewin, S Bozinovski, LAJ O'Neill, T Quach, CJH Porter, DA Brooks, JJ O'Leary, S Selemidis
Nat Commun, 2017-07-12;8(1):69.
Species: Mouse
Sample Types: BALF
-
Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models
Authors: F Yang, J Gu, L Yang, C Gao, H Jing, Y Wang, H Zeng, Q Zou, F Lv, J Zhang
Sci Rep, 2017-06-21;7(1):3957.
Species: Mouse
Sample Types: BALF
-
Chronic intermittent hypoxia induces liver fibrosis in mice with diet-induced obesity via TLR4/MyD88/MAPK/NF-kB signaling pathways
Authors: HH Kang, IK Kim, HI Lee, H Joo, JU Lim, J Lee, SH Lee, HS Moon
Biochem. Biophys. Res. Commun., 2017-06-13;0(0):.
Species: Mouse
Sample Types: Serum
-
NAD(+) augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling
Authors: A Shen, HJ Kim, GS Oh, SB Lee, SH Lee, A Pandit, D Khadka, SK Choe, SC Kwak, SH Yang, EY Cho, HS Kim, H Kim, R Park, TH Kwak, HS So
Sci Rep, 2017-06-07;7(1):3006.
Species: Mouse
Sample Types: Serum
-
STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection
Authors: MT Stier, K Goleniewsk, JY Cephus, DC Newcomb, TP Sherrill, KL Boyd, MH Bloodworth, ML Moore, K Chen, JK Kolls, RS Peebles
J. Immunol., 2017-06-02;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis
Authors: Y Guo, C Xie, X Li, J Yang, T Yu, R Zhang, T Zhang, D Saxena, M Snyder, Y Wu, X Li
Nat Commun, 2017-05-31;8(0):15621.
Species: Mouse
Sample Types: Serum
-
Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production
Authors: H Ahn, E Jeon, JC Kim, SG Kang, SI Yoon, HJ Ko, PH Kim, GS Lee
Sci Rep, 2017-05-02;7(1):1314.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Xenotransplantation of layer-by-layer encapsulated non-human primate islets with a specified immunosuppressive drug protocol
Authors: MR Haque, J Kim, H Park, HS Lee, KW Lee, TA Al-Hilal, JH Jeong, CH Ahn, DS Lee, SJ Kim, Y Byun
J Control Release, 2017-04-19;0(0):.
Species: Mouse
Sample Types: Serum
-
Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology
Authors: SJ Whitfield, C Taylor, JE Risdall, GD Griffiths, JT Jones, ED Williamson, S Rijpkema, L Saraiva, S Vessillier, AC Green, AJ Carter
J. Immunol, 2017-03-20;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Acute fasting inhibits central caspase-1 activity reducing anxiety-like behavior and increasing novel object and object location recognition
Authors: AE Towers, ML Oelschlage, J Patel, SJ Gainey, RH McCusker, GG Freund
Metab. Clin. Exp., 2017-03-09;71(0):70-82.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cthrc1 lowers pulmonary collagen associated with bleomycin-induced fibrosis and protects lung function
Authors: AP Binks, M Beyer, R Miller, RJ LeClair
Physiol Rep, 2017-03-01;5(5):.
Species: Mouse
Sample Types: BALF
-
Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa
Authors: S Hopp, MW Nolte, C Stetter, C Kleinschni, AL Sirén, C Albert-Wei
J Neuroinflammation, 2017-02-20;14(1):39.
Species: Mouse
Sample Types: Plasma
-
Effects of polysaccharide fractions isolated from Caltha palustris L. on the activity of phagocytic cells & humoral immune response in mice with collagen-induced arthritis: A comparison with methotrexate
Authors: A Suszko, B Obmi?ska-M
Indian J. Med. Res., 2017-02-01;145(2):229-236.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adverse Effect Profile of Topical Ocular Administration of Fingolimod for Treatment of Dry Eye Disease
Authors: Weibao Xiao
Basic Clin. Pharmacol. Toxicol, 2017-01-22;0(0):.
Species: Mouse
Sample Types: Tears
-
C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia
PLoS Pathog, 2016-12-06;12(12):e1006038.
Species: Mouse
Sample Types: Tissue Homogenates
-
Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-? Stimulated Gene/Protein 6
Sci Rep, 2016-12-05;6(0):38438.
Species: Mouse
Sample Types: Serum
-
Effects of the stem extracts of Schisandra glaucescens Diels on collagen-induced arthritis in Balb/c mice
Authors: Jinbo Fang
J Ethnopharmacol, 2016-11-10;0(0):.
Species: Mouse
Sample Types: Serum
-
Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice
Sci Rep, 2016-11-07;6(0):36696.
Species: Mouse
Sample Types: Cell Culture Supernates
-
EP4 Receptor-Associated Protein in Macrophages Protects against Bleomycin-Induced Pulmonary Inflammation in Mice
Authors: Manabu Minami
J. Immunol., 2016-10-31;0(0):.
Species: Mouse
Sample Types: BALF
-
Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF
Proc Natl Acad Sci USA, 2016-09-20;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXR? signalling pathway in oxLDL-loaded macrophages
J Cell Mol Med, 2016-09-15;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
KLHDC10 Deficiency Protects Mice against TNF?-Induced Systemic Inflammation
PLoS ONE, 2016-09-15;11(9):e0163118.
Species: Mouse
Sample Types: Serum
-
A Critical Role for P2X7 Receptor-Induced VCAM-1 Shedding and Neutrophil Infiltration during Acute Lung Injury
J Immunol, 2016-08-24;0(0):.
Species: Mouse
Sample Types: BALF
-
Kruppel-like factor 6 promotes macrophage-mediated inflammation by suppressing B cell leukemia/lymphoma 6 expression
J Biol Chem, 2016-08-18;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
DNMT1-PPAR? pathway in macrophages regulates chronic inflammation and atherosclerosis development in mice
Sci Rep, 2016-08-17;6(0):30053.
Species: Mouse
Sample Types: Plasma
-
Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
PLoS ONE, 2016-08-01;11(8):e0158735.
Species: Mouse
Sample Types: BALF
-
Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS
Authors: Yong Hwan Park
Nat Immunol, 2016-06-06;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
Cancer Discov, 2016-04-12;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-kappaB and AP-1 Activation.
Authors: Fan B, Dun S, Gu J, Guo Y, Ikuyama S
PLoS ONE, 2015-09-14;10(9):e0137837.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells.
Authors: Jeschke A, Catala-Lehnen P, Sieber S, Bickert T, Schweizer M, Koehne T, Wintges K, Marshall R, Mautner A, Duchstein L, Otto B, Horst A, Amling M, Kreienkamp H, Schinke T
J Immunol, 2015-09-11;195(8):3675-84.
Species: Mouse
Sample Types: Serum
-
Novel Noncompetitive IL-1 Receptor-Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth.
Authors: Nadeau-Vallee M, Quiniou C, Palacios J, Hou X, Erfani A, Madaan A, Sanchez M, Leimert K, Boudreault A, Duhamel F, Rivera J, Zhu T, Noueihed B, Robertson S, Ni X, Olson D, Lubell W, Girard S, Chemtob S
J Immunol, 2015-08-24;195(7):3402-15.
Species: Mouse
Sample Types: Plasma
-
RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality.
Authors: Meng L, Jin W, Wang X
Proc Natl Acad Sci U S A, 2015-08-17;112(35):11007-12.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
J Immunol, 2015-04-17;194(11):5407-16.
Species: Mouse
Sample Types: BALF
-
Sevoflurane inhibits nuclear factor-kappaB activation in lipopolysaccharide-induced acute inflammatory lung injury via toll-like receptor 4 signaling.
Authors: Sun X, Li X, Wang X, Tan W, Wang J
PLoS ONE, 2015-04-14;10(4):e0122752.
Species: Mouse
Sample Types: BALF
-
Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response.
Authors: O'Callaghan P, Li J, Lannfelt L, Lindahl U, Zhang X
J Biol Chem, 2015-04-13;290(24):14904-14.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice.
Authors: Chien C, Lee M, Liou H, Liou H, Fu W
PLoS ONE, 2015-02-23;10(2):e0115827.
Species: Mouse
Sample Types: Tissue Homogenates
-
Accelerated tumor progression in mice lacking the ATP receptor P2X7.
Authors: Adinolfi E, Capece M, Franceschini A, Falzoni S, Giuliani A, Rotondo A, Sarti A, Bonora M, Syberg S, Corigliano D, Pinton P, Jorgensen N, Abelli L, Emionite L, Raffaghello L, Pistoia V, Di Virgilio F
Cancer Res, 2014-12-26;75(4):635-44.
Species: Mouse
Sample Types: Plasma
-
Chronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6.
Authors: Qiu S, Feng Y, LeSage G, Zhang Y, Stuart C, He L, Li Y, Caudle Y, Peng Y, Yin D
J Immunol, 2014-12-24;194(3):1021-30.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Methylsulfonylmethane inhibits NLRP3 inflammasome activation.
Authors: Ahn H, Kim J, Lee M, Kim Y, Cho Y, Lee G
Cytokine, 2014-11-21;71(2):223-31.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Macrophage control of phagocytosed mycobacteria is increased by factors secreted by alveolar epithelial cells through nitric oxide independent mechanisms.
Authors: Petursdottir D, Chuquimia O, Freidl R, Fernandez C
PLoS ONE, 2014-08-04;9(8):e103411.
Species: Mouse
Sample Types: Cell Culture Supernates
-
PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
Nat Commun, 2014-07-14;5(0):4436.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The effects of protein malnutrition on the TNF-RI and NF-kappaB expression via the TNF-alpha signaling pathway.
Authors: de Oliveira D, Hastreiter A, Mello A, de Oliveira Beltran J, Oliveira Santos E, Borelli P, Fock R
Cytokine, 2014-07-06;69(2):218-25.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of TLR5 and flagella in bacillus intraocular infection.
Authors: Parkunan, Salai Ma, Astley, Roger, Callegan, Michelle
PLoS ONE, 2014-06-24;9(6):e100543.
Species: Mouse
Sample Types: Tissue Homogenates
-
Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1.
Authors: Annamanedi M, Kalle A
PLoS ONE, 2014-06-20;9(6):e99285.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neurodegeneration by activation of the microglial complement-phagosome pathway.
Authors: Bodea L, Wang Y, Linnartz-Gerlach B, Kopatz J, Sinkkonen L, Musgrove R, Kaoma T, Muller A, Vallar L, Di Monte D, Balling R, Neumann H
J Neurosci, 2014-06-18;34(25):8546-56.
Species: Mouse
Sample Types: Plasma
-
Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.
Authors: Xie H, Lu J, Rolhion N, Holden D, Nie P, Zhou Y, Yu X
Infect Immun, 2014-06-02;82(8):3436-45.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The inflammasome pyrin contributes to pertussis toxin-induced IL-1beta synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis.
Authors: Dumas A, Amiable N, de Rivero Vaccari J, Chae J, Keane R, Lacroix S, Vallieres L
PLoS Pathog, 2014-05-29;10(5):e1004150.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Differences in PGE2 production between primary human monocytes and differentiated macrophages: role of IL-1beta and TRIF/IRF3.
Authors: Endo Y, Blinova K, Romantseva T, Golding H, Zaitseva M
PLoS ONE, 2014-05-28;9(5):e98517.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.
Authors: Yamane, Kazuhiko, Indalao, Irene L, Chida, Junji, Yamamoto, Yoshikaz, Hanawa, Masaaki, Kido, Hiroshi
PLoS ONE, 2014-05-27;9(5):e98032.
Species: Mouse
Sample Types: Tissue Homogenates
-
Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain.
Authors: Dengler E, Alberti L, Bowman B, Kerwin A, Wilkerson J, Moezzi D, Limanovich E, Wallace J, Milligan E
J Neuroinflammation, 2014-05-21;11(0):92.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Running exercise alleviates trabecular bone loss and osteopenia in hemizygous beta-globin knockout thalassemic mice.
Authors: Thongchote K, Svasti S, Teerapornpuntakit J, Krishnamra N, Charoenphandhu N
Am J Physiol Endocrinol Metab, 2014-04-29;306(12):E1406-17.
Species: Mouse
Sample Types: Serum
-
NF-kappaB signaling modulates radiationinduced microglial activation.
Authors: Xue J, Dong J, Huang G, Qu X, Wu G, Dong X
Oncol Rep, 2014-04-23;31(6):2555-60.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
Authors: Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A
J Immunol, 2014-03-17;192(8):3816-27.
Species: Mouse
Sample Types: Tissue Homogenates
-
Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
Authors: Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X
J Biol Chem, 2014-03-13;289(16):11522-35.
Species: Mouse
Sample Types: Whole Cells
-
Pseudomonas aeruginosa MucD protease mediates keratitis by inhibiting neutrophil recruitment and promoting bacterial survival.
Authors: Mochizuki Y, Suzuki T, Oka N, Zhang Y, Hayashi Y, Hayashi N, Gotoh N, Ohashi Y
Invest Ophthalmol Vis Sci, 2014-01-09;55(1):240-6.
Species: Mouse
Sample Types: Tissue Homogenates
-
Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.
Authors: Snowden J, Beaver M, Beenken K, Smeltzer M, Horswill A, Kielian T
PLoS ONE, 2013-12-30;8(12):e84089.
Species: Mouse
Sample Types: Tissue Homogenates
-
CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.
Authors: Bignon A, Gaudin F, Hemon P, Tharinger H, Mayol K, Walzer T, Loetscher P, Peuchmaur M, Berrebi D, Balabanian K
J Immunol, 2013-12-23;192(3):886-96.
Species: Mouse
Sample Types: Serum
-
Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.
Authors: Vergadi, Eleni, Vaporidi, Katerina, Theodorakis, Emmanuel, Doxaki, Christin, Lagoudaki, Eleni, Ieronymaki, Elefther, Alexaki, Vassilia, Helms, Mike, Kondili, Eumorfia, Soennichsen, Birte, Stathopoulos, Efstathi, Margioris, Andrew N, Georgopoulos, Dimitrio, Tsatsanis, Christos
J Immunol, 2013-11-25;192(1):394-406.
Species: Mouse
Sample Types: BALF
-
Spironolactone attenuates bleomycin-induced pulmonary injury partially via modulating mononuclear phagocyte phenotype switching in circulating and alveolar compartments.
Authors: Ji W, Ma Y, Zhou X, Zhang Y, Lu R, Guo Z, Sun H, Hu D, Yang G, Li Y, Wei L
PLoS ONE, 2013-11-19;8(11):e81090.
Species: Mouse
Sample Types: BALF
-
Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
Authors: Lin J, Sun B, Jiang C, Hong H, Zheng Y
Biochem Biophys Res Commun, 2013-11-06;441(4):897-903.
Species: Mouse
Sample Types: Serum
-
Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5).
Authors: Wintges K, Beil F, Albers J, Jeschke A, Schweizer M, Claass B, Tiegs G, Amling M, Schinke T
J Bone Miner Res, 2013-10-01;28(10):2070-80.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sufficient production of geranylgeraniol is required to maintain endotoxin tolerance in macrophages.
Authors: Kim J, Lee J, Ye J, Hao R, Debose-Boyd R, Ye J
J Lipid Res, 2013-09-23;54(12):3430-7.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model.
Authors: Besnard A, Struyf S, Guabiraba R, Fauconnier L, Rouxel N, Proost P, Uyttenhove C, Van Snick J, Couillin I, Ryffel B
J Leukoc Biol, 2013-08-23;94(6):1317-23.
Species: Mouse
Sample Types: Tissue Homogenates
-
A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury.
Authors: Campolo M, Esposito E, Ahmad A, Di Paola R, Wallace J, Cuzzocrea S
FASEB J, 2013-07-30;27(11):4489-99.
Species: Mouse
Sample Types: Whole Tissue
-
Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
Authors: Kim, Janice J, Bridle, Byram W, Ghia, Jean-Eri, Wang, Huaqing, Syed, Shahzad, Manocha, Marcus M, Rengasamy, Palanive, Shajib, Mohammad, Wan, Yonghong, Hedlund, Peter B, Khan, Waliul I
J Immunol, 2013-04-03;190(9):4795-804.
Species: Mouse
Sample Types: Tissue Homogenates
-
Sustained interleukin-1beta overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.
Authors: Ghosh S, Wu M, Shaftel S, Kyrkanides S, Laferla F, Olschowka J, O'Banion M
J Neurosci, 2013-03-13;33(11):5053-64.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bcl-2 overexpression ameliorates immune complex-mediated arthritis by altering FcgammaRIIb expression and monocyte homeostasis.
Authors: Lawlor K, van Nieuwenhuijze A, Parker K, Drake S, Campbell I, Smith S, Vince J, Strasser A, Wicks I
J Leukoc Biol, 2013-01-22;93(4):585-97.
Species: Mouse
Sample Types: Cell Culture Supernates
-
mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
Authors: Fan W, Cheng K, Qin X, Narsinh K, Wang S, Hu S, Wang Y, Chen Y, Wu J, Xiong L, Cao F
Stem Cells, 2013-01-01;31(1):203-14.
Species: Mouse
Sample Types: Tissue Homogenates
-
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Authors: Heneka M, Kummer M, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng T, Gelpi E, Halle A, Korte M, Latz E, Golenbock D
Nature, 2012-12-19;493(7434):674-8.
Species: Mouse
Sample Types: Tissue Homogenates
-
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
Authors: Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, Boireau W, Simon B, Ryffel B, Connat J, Kanellopoulos J, Martin F, Rebe C, Apetoh L, Ghiringhelli F
Nat Med, 2012-12-02;19(1):57-64.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Netrin-1 protects against L-Arginine-induced acute pancreatitis in mice.
Authors: Chen J, Cai Q, Shen P, Yan R, Wang C, Yang D, Fu H, Chen X
PLoS ONE, 2012-09-27;7(9):e46201.
Species: Mouse
Sample Types: Plasma
-
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1.
Authors: Broz P, Ruby T, Belhocine K, Bouley D, Kayagaki N, Dixit V, Monack D
Nature, 2012-08-15;490(7419):288-91.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection.
Authors: Huang H, Chen Y, Liang K, Jheng Y, Jhao J, Su M, Lee-Chen G, Hsieh-Li H
PLoS ONE, 2012-07-23;7(7):e39656.
Species: Mouse
Sample Types: Plasma
-
Treatment of diabetic mice with undenatured whey protein accelerates the wound healing process by enhancing the expression of MIP-1alpha, MIP-2, KC, CX3CL1 and TGF-beta in wounded tissue.
BMC Immunol., 2012-06-18;13(0):32.
Species: Mouse
Sample Types: Tissue Homogenates
-
Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
Authors: Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ
J. Biol. Chem., 2012-03-23;287(20):16356-64.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-kappaB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury.
J. Cell. Sci., 2012-03-16;91(6):921-32.
Species: Mouse
Sample Types: BALF
-
The axonal guidance receptor neogenin promotes acute inflammation.
Authors: Konig K, Gatidou D, Granja T, Meier J, Rosenberger P, Mirakaj V
PLoS ONE, 2012-03-06;7(3):e32145.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012-01-18;7(1):e30005.
Species: Mouse
Sample Types: Tissue Homogenates
-
Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.
Authors: Deng T, Zhang Y, Chen Q, Yan K, Han D
Immunology, 2012-01-01;135(1):40-50.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sphingosine regulates the NLRP3-inflammasome and IL-1beta release from macrophages.
Authors: Luheshi NM, Giles JA, Lopez-Castejon G, Brough D
Eur. J. Immunol., 2011-12-27;42(3):716-25.
Species: Mouse
Sample Types: Cell Culture Supernates
-
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
Authors: Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD
PLoS Genet., 2011-10-20;7(10):e1002336.
Species: Mouse
Sample Types: Serum
-
Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-alpha stimulated gene/protein 6.
Authors: Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH, Prockop DJ
Stem Cells, 2011-10-01;29(10):1572-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
WNT5A Signaling Contributes to Abeta-Induced Neuroinflammation and Neurotoxicity.
Authors: Li B, Zhong L, Yang X, Andersson T, Huang M, Tang SJ
PLoS ONE, 2011-08-17;6(8):e22920.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis.
Authors: Nakahama T, Kimura A, Nguyen NT, Chinen I, Hanieh H, Nohara K, Fujii-Kuriyama Y, Kishimoto T
Proc. Natl. Acad. Sci. U.S.A., 2011-08-08;108(34):14222-7.
Species: Mouse
Sample Types: Serum
-
Role of IL-1alpha and the Nlrp3/caspase-1/IL-1beta axis in cigarette smoke-induced pulmonary inflammation and COPD.
Authors: Pauwels NS, Bracke KR, Dupont LL, Van Pottelberge GR, Provoost S, Vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Brusselle GG
Eur. Respir. J., 2011-05-26;38(5):1019-28.
Species: Mouse
Sample Types: BALF
-
IL-33-activated dendritic cells are critical for allergic airway inflammation.
Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
Eur. J. Immunol., 2011-05-25;41(6):1675-86.
Species: Mouse
Sample Types: BALF
-
Crawling Phagocytes Recruited in the Brain Vasculature after Pertussis Toxin Exposure through IL6, ICAM1 and ITGalphaM.
Authors: Richard JF, Roy M, Audoy-Remus J, Tremblay P, Vallieres L
Brain Pathol., 2011-05-23;21(0):661.
Species: Mouse
Sample Types: Serum
-
Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
Am. J. Pathol., 2011-05-10;179(1):302-14.
Species: Mouse
Sample Types: Tissue Homogenates
-
Fasting induces an anti-inflammatory effect on the neuroimmune system which a high-fat diet prevents.
Authors: Lavin DN, Joesting JJ, Chiu GS, Moon ML, Meng J, Dilger RN, Freund GG
Obesity (Silver Spring), 2011-04-28;19(8):1586-94.
Species: Mouse
Sample Types: Serum
-
Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation.
Authors: Mirakaj V, Brown S, Laucher S, Steinl C, Klein G, Kohler D, Skutella T, Meisel C, Brommer B, Rosenberger P, Schwab JM
Proc. Natl. Acad. Sci. U.S.A., 2011-04-05;108(16):6555-60.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10.
Authors: Wang H, Cheng F
J. Immunol., 2011-03-02;186(0):3986.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Serotonin activates dendritic cell function in the context of gut inflammation.
Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
Am. J. Pathol., 2011-02-01;178(2):662-71.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence.
Authors: Kaplan IM, Morisot S, Heiser D, Cheng WC, Kim MJ, Civin CI
J. Immunol., 2011-01-26;186(5):2826-34.
Species: Mouse
Sample Types: Plasma
-
TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
J. Immunol., 2010-11-22;186(1):556-62.
Species: Mouse
Sample Types: BALF
-
Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.
Authors: Brenneis C, Coste O, Altenrath K, Angioni C, Schmidt H, Schuh CD, Zhang DD, Henke M, Weigert A, Brune B, Rubin B, Nusing R, Scholich K, Geisslinger G
J. Biol. Chem., 2010-11-12;286(3):2331-42.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages.
Authors: McCoy AJ, Koizumi Y, Toma C, Higa N, Dixit V, Taniguchi S, Tschopp J, Suzuki T
Eur. J. Immunol., 2010-10-01;40(10):2797-803.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes.
Authors: Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nunez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA
Nat. Immunol., 2010-09-12;11(10):897-904.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.
Authors: Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Muller S, Follo M, Peters C, Reinheckel T
Oncogene, 2010-09-06;30(1):54-64.
Species: Mouse
Sample Types: Tissue Homogenates
-
TLR4 is a negative regulator in noninfectious lung inflammation.
Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
J. Immunol., 2010-03-31;184(9):5308-14.
Species: Mouse
Sample Types: BALF
-
Loss of ability to self-heal malaria upon taurine transporter deletion.
Authors: Delic D, Warskulat U, Borsch E, Al-Qahtani S, Al-Quraishi S, Haussinger D, Wunderlich F
Infect. Immun., 2010-01-25;78(4):1642-9.
Species: Mouse
Sample Types: Serum
-
Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta.
Authors: Lewis SS, Hutchinson MR, Rezvani N, Loram LC, Zhang Y, Maier SF, Rice KC, Watkins LR
Neuroscience, 2010-01-20;165(2):569-83.
Species: Mouse
Sample Types: Cell Lysates
-
Galectin-3 contributes to neonatal hypoxic-ischemic brain injury.
Authors: Doverhag C, Hedtjarn M, Poirier F, Mallard C, Hagberg H, Karlsson A, Savman K
Neurobiol. Dis., 2010-01-04;38(1):36-46.
Species: Mouse
Sample Types: Tissue Homogenates
-
Absence or inhibition of matrix metalloproteinase-8 decreases ventilator-induced lung injury.
Authors: Albaiceta GM, Gutierrez-Fernandez A, Garcia-Prieto E, Puente XS, Parra D, Astudillo A, Campestre C, Cabrera S, Gonzalez-Lopez A, Fueyo A, Taboada F, Lopez-Otin C
Am. J. Respir. Cell Mol. Biol., 2009-12-07;43(5):555-63.
Species: Mouse
Sample Types: Tissue Homogenates
-
Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
J. Invest. Dermatol., 2009-11-19;130(3):866-75.
Species: Mouse
Sample Types: Tissue Homogenates
-
Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept.
Authors: Aden U, Favrais G, Plaisant F, Winerdal M, Felderhoff-Mueser U, Lampa J, Lelievre V, Gressens P
Brain Behav. Immun., 2009-10-25;24(5):747-58.
Species: Mouse
Sample Types: Tissue Homogenates
-
Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
Authors: Sio SW, Moochhala S, Lu J
Am. J. Respir. Crit. Care Med., 2009-10-01;181(1):36-46.
Species: Mouse
Sample Types: Tissue Homogenates
-
Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.
Authors: Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-09-25;298(1):L67-78.
Species: Mouse
Sample Types: BALF
-
Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
Am. J. Respir. Crit. Care Med., 2009-09-17;180(12):1208-17.
Species: Mouse
Sample Types: BALF
-
Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice.
Authors: Mizutani N, Nabe T, Yoshino S
J. Immunol., 2009-08-14;183(6):4039-46.
Species: Mouse
Sample Types: BALF
-
Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
Authors: Hayashida K, Parks WC, Park PW
Blood, 2009-07-28;114(14):3033-43.
Species: Mouse
Sample Types: Serum
-
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
J Biol Chem, 2009-07-15;284(36):24035-48.
Species: Mouse
Sample Types: Plasma
-
Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice.
Authors: Surguladze D, Deevi D, Claros N, Corcoran E, Wang S, Plym MJ, Wu Y, Doody J, Mauro DJ, Witte L, Busam KJ, Pytowski B, Rodeck U, Tonra JR
Cancer Res., 2009-07-07;69(14):5643-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
Authors: Pushparaj PN, Tay HK, Wang CC, Hong W, Melendez AJ
J. Immunol., 2009-06-29;183(2):1413-8.
Species: Mouse
Sample Types: Serum
-
A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
J. Immunol., 2009-06-19;183(2):1291-300.
Species: Mouse
Sample Types: BALF
-
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
Nature, 2009-06-03;460(7252):269-73.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Secretory lysosome targeting and induced secretion of human soluble TNF-alpha receptor in murine hematopoietic cells in vivo as a principle for immunoregulation in inflammation and malignancy.
Authors: Johansson AC, Nandakumar KS, Persson AM, Olsson I, Hansson M
Exp. Hematol., 2009-05-30;37(8):969-78.
Species: Mouse
Sample Types: Cell Culture Supernates
-
C/EBPalpha is required for pulmonary cytoprotection during hyperoxia.
Authors: Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-05-22;297(2):L286-98.
Species: Mouse
Sample Types: Tissue Homogenates
-
Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis.
Authors: Reed JR, Leon RP, Hall MK, Schwertfeger KL
Breast Cancer Res., 2009-04-24;11(2):R21.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro.
Authors: Wang C, Duan H, He L
Eur. J. Pharmacol., 2009-04-06;612(1):143-52.
Species: Mouse
Sample Types: Air Pouch Exudate
-
Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
Int. Immunol., 2009-03-18;21(5):555-65.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells.
Authors: Tao JY, Zheng GH, Zhao L, Wu JG, Zhang XY, Zhang SL, Huang ZJ, Xiong FL, Li CM
J Ethnopharmacol, 2009-03-03;123(1):97-105.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages.
Authors: Cheon MS, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK
J Ethnopharmacol, 2009-02-03;122(3):473-7.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
J. Neuroimmunol., 2009-02-01;208(1):54-60.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.
Authors: Caruso R, Stolfi C, Sarra M, Rizzo A, Fantini MC, Pallone F, MacDonald TT, Monteleone G
Blood, 2009-01-07;113(15):3512-9.
Species: Mouse
Sample Types: Serum
-
Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia.
Authors: Rosenberger P, Schwab JM, Mirakaj V, Masekowsky E, Mager A, Morote-Garcia JC, Unertl K, Eltzschig HK
Nat. Immunol., 2009-01-04;10(2):195-202.
Species: Mouse
Sample Types: Serum
-
p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia.
Authors: Liu Q, Cheng LI, Yi L, Zhu N, Wood A, Changpriroa CM, Ward JM, Jackson SH
Am. J. Pathol., 2008-12-18;174(1):153-63.
Species: Mouse
Sample Types: BALF
-
NOD1 expression in the eye and functional contribution to IL-1beta-dependent ocular inflammation in mice.
Authors: Rosenzweig HL, Galster KT, Planck SR, Rosenbaum JT
Invest. Ophthalmol. Vis. Sci., 2008-12-13;50(4):1746-53.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
Int. Immunol., 2008-12-09;21(1):81-93.
Species: Mouse
Sample Types: Tissue Homogenates
-
Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2008-09-17;75(1):52-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
Authors: Zhang H, Moochhala SM, Bhatia M
J. Immunol., 2008-09-15;181(6):4320-31.
Species: Mouse
Sample Types: Tissue Homogenates
-
Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
Authors: Leoni G, Patel HB, Sampaio AL, Gavins FN, Murray JF, Grieco P, Getting SJ, Perretti M
FASEB J., 2008-08-29;22(12):4228-38.
Species: Mouse
Sample Types: Plasma
-
Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.
Authors: Paul R, Obermaier B, Van Ziffle J, Angele B, Pfister HW, Lowell CA, Koedel U
J. Leukoc. Biol., 2008-07-14;84(4):1141-50.
Species: Mouse
Sample Types: Tissue Homogenates
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Authors: Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT
Nat. Immunol., 2008-07-11;9(8):857-65.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
Eur. J. Pharmacol., 2008-06-16;590(1):400-8.
Species: Mouse
Sample Types: Tissue Homogenates
-
The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
J. Immunol., 2008-06-15;180(12):8333-41.
Species: Mouse
Sample Types: Tissue Homogenates
-
Purine receptor antagonist modulates serology and affective behaviors in lupus-prone mice: evidence of autoimmune-induced pain?
Authors: Ballok DA, Sakic B
Brain Behav. Immun., 2008-06-14;0(0):.
Species: Mouse
Sample Types: Serum
-
Activation of NOD2 in vivo induces IL-1beta production in the eye via caspase-1 but results in ocular inflammation independently of IL-1 signaling.
Authors: Rosenzweig HL, Martin TM, Planck SR, Galster K, Jann MM, Davey MP, Kobayashi K, Flavell RA, Rosenbaum JT
J. Leukoc. Biol., 2008-05-21;84(2):529-36.
Species: Mouse
Sample Types: Tissue Homogenates
-
Functional roles for C5a receptors in sepsis.
Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
Nat. Med., 2008-05-04;14(5):551-7.
Species: Mouse
Sample Types: Plasma
-
Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice.
Authors: Doverhag C, Keller M, Karlsson A, Hedtjarn M, Nilsson U, Kapeller E, Sarkozy G, Klimaschewski L, Humpel C, Hagberg H, Simbruner G, Gressens P, Savman K
Neurobiol. Dis., 2008-04-25;31(1):133-44.
Species: Mouse
Sample Types: Tissue Homogenates
-
Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages.
Authors: Pae HO, Jeong SO, Koo BS, Ha HY, Lee KM, Chung HT
Biochem. Biophys. Res. Commun., 2008-04-22;371(3):361-5.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation.
Authors: Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG, Kim YM
Biochem. Pharmacol., 2008-04-18;76(1):79-90.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adverse functions of IL-17A in experimental sepsis.
Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
FASEB J., 2008-02-25;22(7):2198-205.
Species: Mouse
Sample Types: Plasma
-
Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics.
Authors: Umemura N, Saio M, Suwa T, Kitoh Y, Bai J, Nonaka K, Ouyang GF, Okada M, Balazs M, Adany R, Shibata T, Takami T
J. Leukoc. Biol., 2008-02-19;83(5):1136-44.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
Nat. Med., 2008-02-03;14(2):199-204.
Species: Mouse
Sample Types: BALF
-
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
J. Immunol., 2008-01-01;180(1):609-17.
Species: Mouse
Sample Types: Tissue Secretion
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Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
Authors: Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR
Transplantation, 2007-11-27;84(10):1279-87.
Species: Mouse
Sample Types: Serum
-
Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk.
Authors: Ryu M, Kim EH, Chun M, Kang S, Shim B, Yu YB, Jeong G, Lee JS
J Ethnopharmacol, 2007-10-05;115(2):184-93.
Species: Mouse
Sample Types: Air Pouch Exudate
-
Maternal immune activation alters fetal brain development through interleukin-6.
Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
J. Neurosci., 2007-10-03;27(40):10695-702.
Species: Mouse
Sample Types: Serum
-
ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
Authors: Huang X, Du W, Barrett RP, Hazlett LD
Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4626-33.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4498-508.
Species: Mouse
Sample Types: Tissue Homogenates
-
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.
Authors: Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J
Nat. Med., 2007-09-02;13(9):1042-9.
Species: Mouse
Sample Types: Serum
-
Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
Crit. Care Med., 2007-08-01;35(8):1955-60.
Species: Mouse
Sample Types: Plasma
-
Neuronal NF-kappaB influences thermoregulation and survival in a sepsis model.
Authors: Juttler E, Inta I, Eigler V, Herrmann O, Maegele I, Maser-Gluth C, Schwaninger M
J. Neuroimmunol., 2007-07-25;189(1):41-9.
Species: Mouse
Sample Types: Serum
-
Acute brain injury triggers MyD88-dependent, TLR2/4-independent inflammatory responses.
Authors: Koedel U, Merbt UM, Schmidt C, Angele B, Popp B, Wagner H, Pfister HW, Kirschning CJ
Am. J. Pathol., 2007-07-01;171(1):200-13.
Species: Mouse
Sample Types: Tissue Homogenates
-
Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
Am. J. Physiol. Lung Cell Mol. Physiol., 2007-06-01;293(2):L491-6.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi.
Authors: Medeiros MM, Peixoto JR, Oliveira AC, Cardilo-Reis L, Koatz VL, Van Kaer L, Previato JO, Mendonca-Previato L, Nobrega A, Bellio M
J. Leukoc. Biol., 2007-05-31;82(3):488-96.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
Authors: Nguyen M, Pace AJ, Koller BH
J. Exp. Med., 2007-05-21;204(6):1383-93.
Species: Mouse
Sample Types: Tissue Homogenates
-
The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
Authors: Fujita H, Asahina A, Komine M, Tamaki K
Cell. Immunol., 2007-05-15;245(2):70-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior.
Authors: Lowry CA, Hollis JH, de Vries A, Pan B, Brunet LR, Hunt JR, Paton JF, van Kampen E, Knight DM, Evans AK, Rook GA, Lightman SL
Neuroscience, 2007-03-23;146(2):756-72.
Species: Mouse
Sample Types: Plasma
-
Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
Am. J. Pathol., 2007-03-01;170(3):1003-17.
Species: Mouse
Sample Types: Serum
-
Cell-based angiopoietin-1 gene therapy for acute lung injury.
Authors: McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ
Am. J. Respir. Crit. Care Med., 2007-02-22;175(10):1014-26.
Species: Mouse
Sample Types: BALF
-
The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
Life Sci., 2007-02-03;80(20):1821-31.
Species: Mouse
Sample Types: BALF
-
The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.
Authors: Chang CP, Huang WT, Cheng BC, Hsu CC, Lin MT
Neuropharmacology, 2007-01-03;52(3):1024-33.
Species: Mouse
Sample Types: Serum
-
Tetrathiomolybdate is effective in a mouse model of arthritis.
Authors: McCubbin MD, Hou G, Abrams GD, Dick R, Brewer GJ
J. Rheumatol., 2006-10-15;33(12):2501-6.
Species: Mouse
Sample Types: Serum
-
The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2006-10-11;70(11):1942-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
Arthritis Rheum., 2006-10-01;54(10):3182-93.
Species: Mouse
Sample Types: Tissue Homogenates
-
Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells.
Authors: Deng L, Dai P, Ding W, Granstein RD, Shuman S
J. Virol., 2006-10-01;80(20):9977-87.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
Int. Immunol., 2006-09-11;18(11):1531-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
[D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse).
Authors: Getting SJ, Lam CW, Leoni G, Gavins FN, Grieco P, Perretti M
Mol. Pharmacol., 2006-09-07;70(6):1850-5.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
Am. J. Physiol. Lung Cell Mol. Physiol., 2006-08-04;291(6):L1246-55.
Species: Mouse
Sample Types: Tissue Homogenates
-
Allergic airway inflammation inhibits pulmonary antibacterial host defense.
Authors: Beisswenger C, Kandler K, Hess C, Garn H, Felgentreff K, Wegmann M, Renz H, Vogelmeier C, Bals R
J. Immunol., 2006-08-01;177(3):1833-7.
Species: Mouse
Sample Types: BALF
-
Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation.
Authors: Card JW, Carey MA, Bradbury JA, DeGraff LM, Morgan DL, Moorman MP, Flake GP, Zeldin DC
J. Immunol., 2006-07-01;177(1):621-30.
Species: Mouse
Sample Types: BALF
-
Organ-specific role of MyD88 for gene regulation during polymicrobial peritonitis.
Authors: Weighardt H, Mages J, Jusek G, Kaiser-Moore S, Lang R, Holzmann B
Infect. Immun., 2006-06-01;74(6):3618-32.
Species: Mouse
Sample Types: Tissue Homogenates
-
Absence of IL-1 receptor antagonist impaired wound healing along with aberrant NF-kappaB activation and a reciprocal suppression of TGF-beta signal pathway.
Authors: Ishida Y, Kondo T, Kimura A, Matsushima K, Mukaida N
J. Immunol., 2006-05-01;176(9):5598-606.
Species: Mouse
Sample Types: Tissue Homogenates
-
Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung.
Authors: Andre E, Stoeger T, Takenaka S, Bahnweg M, Ritter B, Karg E, Lentner B, Reinhard C, Schulz H, Wjst M
Eur. Respir. J., 2006-04-26;28(2):275-85.
Species: Mouse
Sample Types: BALF
-
Protease-activated receptor-2 activation: a major role in the pathogenesis of Porphyromonas gingivalis infection.
Authors: Holzhausen M, Spolidorio LC, Ellen RP, Jobin MC, Steinhoff M, Andrade-Gordon P, Vergnolle N
Am. J. Pathol., 2006-04-01;168(4):1189-99.
Species: Mouse
Sample Types: Blister Fluid
-
Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters.
Authors: Li RW, Theriault AG, Au K, Douglas TD, Casaschi A, Kurowska EM, Mukherjee R
Life Sci., 2006-02-21;79(4):365-73.
Species: Mouse
Sample Types: Serum
-
Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
Authors: Weijer S, Florquin S, van der Poll T
Shock, 2005-01-01;23(1):54-8.
Species: Mouse
Sample Types: Peritoneal Fluid
-
The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
Authors: Cotena A, Platt N
J. Immunol., 2004-11-15;173(10):6427-32.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cytokine expression in experimental chronic otitis media with effusion in mice.
Authors: Maeda K, Hirano T, Ichimiya I, Kurono Y, Suzuki M, Mogi G
Laryngoscope, 2004-11-01;114(11):1967-72.
Species: Mouse
Sample Types: Tissue Secretion
-
IL-1 receptor-associated kinase 1 mediates protection against Staphylococcus aureus infection.
Authors: Verdrengh M, Thomas JA, Hultgren OH
Microbes Infect., 2004-11-01;6(14):1268-72.
Species: Mouse
Sample Types: Serum
-
Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes.
Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF
Comp. Immunol. Microbiol. Infect. Dis., 2004-11-01;27(6):393-411.
Species: Mouse
Sample Types: Serum
-
Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
Authors: Thakur A, Barrett RP, McClellan S, Hazlett LD
Curr. Eye Res., 2004-10-01;29(4):225-33.
Species: Mouse
Sample Types: Tissue Homogenates
-
Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts.
Authors: Tanaka M, Terry RD, Mokhtari GK, Inagaki K, Koyanagi T, Kofidis T, Mochly-Rosen D, Robbins RC
Circulation, 2004-09-14;110(11):II194-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
J. Exp. Med., 2004-05-17;199(10):1355-65.
Species: Mouse
Sample Types: Serum
-
Responses of guinea pig pups during isolation in a novel environment may represent stress-induced sickness behaviors.
Authors: Hennessy MB, Deak T, Schiml-Webb PA, Wilson SE, Greenlee TM, McCall E
Physiol. Behav., 2004-03-01;81(1):5-13.
Species: Guinea Pig
Sample Types: Serum
-
Systemic up-regulation of sTNFR2 and IL-6 in Porphyromonas gingivalis pneumonia in mice.
Authors: Petelin M, Naruishi K, Shiomi N, Mineshiba J, Arai H, Nishimura F, Takashiba S, Murayama Y
Exp. Mol. Pathol., 2004-02-01;76(1):76-81.
Species: Mouse
Sample Types: Serum
-
Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
Blood, 2003-10-30;103(5):1702-9.
Species: Mouse
Sample Types: BALF
-
Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
Infect. Immun., 2003-04-01;71(4):2276-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor.
Authors: Getting SJ, Christian HC, Lam CW, Gavins FN, Flower RJ, Schioth HB, Perretti M
J. Immunol., 2003-03-15;170(6):3323-30.
Species: Mouse
Sample Types: Peritoneal Fluid
-
IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
J. Immunol., 2003-02-15;170(4):2106-12.
Species: Mouse
Sample Types: BALF
-
Caspase-1-deficient mice have delayed neutrophil apoptosis and a prolonged inflammatory response to lipopolysaccharide-induced acute lung injury.
Authors: Rowe SJ, ECfDá, Allen L, Ridger VC, Hellewell PG, Whyte MK
2002-12-01;169(11):6401-7.
Species: Mouse
Sample Types: BALF
-
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001-07-01;31(7):2104-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dendritic cells phagocytose and are activated by Treponema pallidum.
Authors: Bouis DA, Popova TG, Takashima A, Norgard MV
Infect. Immun., 2001-01-01;69(1):518-28.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia.
Authors: Yates SL, Burgess LH, Kocsis-Angle J, Antal JM, Dority MD, Embury PB, Piotrkowski AM, Brunden KR
J. Neurochem., 2000-03-01;74(3):1017-25.
Species: Mouse
Sample Types: Cell Culture Supernates
FAQs
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Does the Mouse IL-1 beta/IL-1F2 Quantikine ELISA (Catalog # MLB00C) cross-react with the pro-form of Mouse IL-1 beta?
The Mouse IL-1 beta/IL-1F2 Quantikine ELISA is designed to detect mature mouse IL-1 beta and the assay is calibrated against recombinant mouse IL-1 beta. It is possible that the kit also detects the pro-form, however, R&D Systems has not performed this characterization.
Reviews for Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
Average Rating: 4.8 (Based on 19 Reviews)
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Undiluted mouse plasma samples
Easy perform and works great!
Mouse serum
Hippocampus: sensitivity is good for detection of samples with dilution not more than 4X.
Highly sensitive ELISA very easy to work with. Don't normally dilute samples.
One of the best ELISA kits for interleukin- 1 beta estimation. I have used kits from 2 other vendors but the reproducibility with this kit is uncomparable. I am blindly thinking of RnD systems from my ELISA requirements after using this kit.
Among best ELISAs I've worked with. Great consistency lot to lot, high sensitivity, easy to work with small amount of samples (usually dilute mouse plasma 1:10). Appropriate for concentration response curves.
highly recommend.