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Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit

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Mouse IL-1 beta/IL-1F2 ELISA Standard Curve
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Summary Sample Values Precision Recovery Linearity Data Examples Product Datasheets Preparation and Storage Background Related Research Areas

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit Summary

Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (50 uL), Tissue Lysates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)
Sensitivity
4.8 pg/mL
Assay Range
12.5 - 800 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma)
Specificity
Natural and recombinant mouse IL-1 beta
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Sample Values

Serum/Plasma - Twenty samples were evaluated for the presence of mouse IL-1 beta in this assay. Serum samples measured as shown in the table below. All twenty plasma samples measured less than the lowest Mouse IL-1 beta Standard, 12.5 pg/mL.

Sample TypeMean of Detectable (pg/mL)% DetectableRange (pg/mL)
Serum (n=20)27.610ND-37.9
ND=Non-detectable

Cell Culture Supernates - J774A.1 mouse reticulum cell sarcoma macrophage cells (3.5 x 106 cells/mL) were cultured in DMEM supplemented with 10% fetal bovine serum and stimulated with 5 μM beta -mercapthoethanol, 2 mM L-glutamine, 100 U/mL penicillin, and 100 μg/mL streptomycin sulfate. The cell culture supernate was unstimulated or stimulated with 2.5 μg/mL of lipopolysacharride (LPS) and 100 ng/mL of recombinant mouse GM-CSF (R&D Systems, Catalog # 415-ML) for 3 and 6 days. Aliquots of the cell culture supernates were removed and assayed for levels of mouse IL-1 beta.

Sample TypeDay 3 (pg/mL)Day 6 (pg/mL)
J774A.1 UnstimulatedNDND
J774A.1 Stimulated with LPS + GM-CSF587938
ND=Non-detectable

Tissue Lysates - Organs from 2-3 mice were rinsed with PBS to remove excess blood, chopped into 1-2 mm pieces, homogenized with a tissue homogenizer, and 1 mL of Lysis Buffer 2 was added (2 mL of Lysis Buffer 2 was added to liver tissue). Organs were lysed at room temperature for 30 minutes with gentle agitation and centrifuged to remove debris. An aliquot of each tissue lysate was removed and assayed for levels of mouse IL-1 beta.

Tissue Lysate(pg/mL)
Brain20.9
Heart28.3
Kidney111
Liver347
Lung115
Spleen987





Product Summary

The Quantikine® Mouse IL-1 beta Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IL-1 beta in cell culture supernates, tissue lysates, serum, and plasma. It contains E. coli-expressed recombinant mouse IL-1 beta and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant factor accurately. Results obtained using natural mouse IL-1 beta showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-1 beta.

Precision

Intra-Assay Precision (Precision within an assay)
Inter-Assay Precision (Precision between assays)

Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 33.5 92.9 386 34.6 93.5 423
Standard Deviation 2.5 4.3 11.7 2.9 6.2 23.9
CV% 7.5 4.6 3 8.4 6.6 5.7

Recovery

The recovery of mouse IL-1 beta spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=4) 106 95-119
EDTA Plasma (n=4) 108 101-117
Heparin Plasma (n=4) 97 87-114
Serum (n=4) 105 98-113
Tissue Lysates (n=4) 115 110-120

Linearity

To assess the linearity of the assay, samples containing and/or spiked with high concentrations of mouse IL-1 beta were serially diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Mouse IL-1 beta/IL-1F2 ELISA Linearity

Scientific Data

N/A Mouse IL-1 beta/IL-1F2 ELISA Standard Curve View Larger

Mouse IL-1 beta/IL-1F2 ELISA Standard Curve

N/A Human E‑Cadherin Antibody View Larger

Human E‑Cadherin Antibody PYC suppressed LPS-induced proinflammatory cytokine production in BV2 microglia.Cells were incubated with the indicated concentrations of PYC or vehicle for 1h before LPS treatment (500ng/mL). After 24 h incubation, the culture supernatants were collected, and the amount of TNF-alpha, IL-6, IL-1 beta and IL-10 were measured by ELISA (A-D). Data are represented as mean ± SD from at least 3 independent experiments. *P< 0.05 compared with LPS alone. #P< 0.05. Image collected and cropped by CiteAb from the following open publication (https://dx.plos.org/10.1371/journal.pone.0137837), licensed under a CC-BY license. Not internally tested by R&D Systems.

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-1 beta/IL-1F2

The Interleukin 1 (IL-1) family of proteins consists of IL-1 alpha, IL-1 beta, and the IL-1 receptor antagonist (IL-1ra). IL-1 alpha and IL-1 beta bind to the same cell surface receptors and share biological functions (1). IL-1 is not produced by unstimulated cells of healthy individuals with the exception of skin keratinocytes, some epithelial cells, and certain cells of the central nervous system. However, in response to inflammatory agents, infections, or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cell types is seen. IL-1 beta plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. Inappropriate or prolonged production of IL-1 has been implicated in a variety of pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulindependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases (2-5). 

 IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid (aa) level. Both are synthesized as 31 kDa precursors that are subsequently cleaved into mature proteins of approximately 17.5 kDa (6, 7). Cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response (2, 8). Neither IL-1 alpha nor IL-1 beta contains a typical hydrophobic signal peptide (9-11), but evidence suggests that these factors can be secreted by non-classical pathways (12, 13). A portion of unprocessed IL-1 alpha can be presented on the cell membrane and may retain biological activity (14). The precursor form of IL-1 beta, unlike the IL-1 alpha precursor, shows little or no biological activity in comparison to the processed form (13, 15). Both unprocessed and mature forms of IL-1 beta are exported from the cell. 
 IL-1 alpha and IL-1 beta exert their effects through immunoglobulin superfamily receptors that additionally bind IL-1ra. The 80 kDa transmembrane type I receptor (IL-1 RI) is expressed on T cells, fibroblasts, keratinocytes, endothelial cells, synovial lining cells, chondrocytes, and hepatocytes (16, 17). The 68 kDa transmembrane type II receptor (IL-1 RII) is expressed on B cells, neutrophils, and bone marrow cells (18). The two IL-1 receptor types show approximately 28% homology in their extracellular domains but differ significantly in that the type II receptor has a cytoplasmic domain of only 29 aa, whereas the type I receptor has a 213 aa cytoplasmic domain. IL-1 RII does not appear to signal in response to IL-1 and may function as a decoy receptor that attenuates IL-1 function (19). The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction (20). IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 (21, 22). Soluble forms of both IL-1 RI and IL-1 RII have been detected in human plasma, synovial fluids, and the conditioned media of several human cell lines (23, 24). In addition, IL-1 binding proteins that resemble soluble IL-1 RII are encoded by vaccinia and cowpox viruses (25).

Long Name:
Interleukin 1 beta
Entrez Gene IDs:
3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig)
Alternate Names:
catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
&#9888; WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Citations for Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

518 Citations: Showing 1 - 10
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  1. Enoximone alleviates atopic dermatitis-like skin inflammation via inhibition of type 2 T helper cell development
    Authors: Song, JY;Lee, YJ;Lee, SH;Lee, JY;
    International immunopharmacology
    Species: Mouse
    Sample Types: Serum
  2. Acacetin protects against acute lung injury by upregulating SIRT1/ NF-?B pathway
    Authors: Gu, L;Yin, Y;Liu, M;Yu, L;
    Heliyon
    Species: Human, Mouse
    Sample Types: Cell Culture Supernates, BALF
  3. Serum CIAPIN1 is lower in septic patients with cardiac dysfunction
    Authors: Xu, N;Wan, J;Wang, C;Chen, L;
    Peptides
    Species: Rat
    Sample Types: Cell Culture Supernates
  4. Akkermansia muciniphila alleviates abdominal aortic aneurysms via restoring CITED2 activated by EPAS1
    Authors: Wang, S;Shi, H;Cheng, Y;Jiang, L;Lou, Y;Kumar, M;Sun, M;Shao, X;Zhao, X;Wang, B;
    Infection and immunity
    Species: Mouse
    Sample Types: Cell Culture Supernates, Tissue Homogenates
  5. Plexin C1 influences immune response to intracellular LPS and survival in murine sepsis
    Authors: Bernard, A;Eggstein, C;Tang, L;Keller, M;Körner, A;Mirakaj, V;Rosenberger, P;
    Journal of biomedical science
    Species: Transgenic Mouse
    Sample Types: Cell Culture Supernates, Peritoneal Lavage Fluid
  6. Macrophage WDFY3, a protector against autoimmunity
    Authors: Wu, X;Wang, Z;Croce, KR;Li, F;Cui, J;D'Agati, VD;Soni, RK;Khalid, S;Saleheen, D;Tabas, I;Yamamoto, A;Zhang, H;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Cell Culture Supernates
  7. Huperzine a ameliorates sepsis-induced acute lung injury by suppressing inflammation and oxidative stress via ?7 nicotinic acetylcholine receptor
    Authors: Su, J;Chen, K;Sang, X;Feng, Z;Zhou, F;Zhao, H;Wu, S;Deng, X;Lin, C;Lin, X;Xie, L;Ye, H;Chen, Q;
    International immunopharmacology
    Species: Mouse
    Sample Types: Tissue Homogenates
  8. Combining Aloin with TIENAM ameliorates cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating abdominal cavity microbiota
    Authors: Su, J;Xiao, J;Deng, X;Lin, X;Xie, L;Ye, H;Lin, C;Zhou, F;Wu, S;
    International immunopharmacology
    Species: Mouse
    Sample Types: Serum, Tissue Homogenates
  9. DNA-sensing inflammasomes cause recurrent atherosclerotic stroke
    Authors: Cao, J;Roth, S;Zhang, S;Kopczak, A;Mami, S;Asare, Y;Georgakis, MK;Messerer, D;Horn, A;Shemer, R;Jacqmarcq, C;Picot, A;Green, JP;Schlegl, C;Li, X;Tomas, L;Dutsch, A;Liman, TG;Endres, M;Wernsdorf, SR;Fürle, C;Carofiglio, O;Zhu, J;Brough, D;DEMDAS Study Group, ;Hornung, V;Dichgans, M;Vivien, D;Schulz, C;Dor, Y;Tiedt, S;Sager, HB;Grosse, GM;Liesz, A;
    Nature
    Species: Mouse
    Sample Types: Tissue Homogenates
  10. CKD-497 inhibits NF-kB signaling and ameliorates inflammation and pulmonary fibrosis in ovalbumin-induced asthma and particulate matter-induced airway inflammatory diseases
    Authors: Kim, H;Choi, J;Seo, J;Lim, H;Kang, SK;
    Frontiers in pharmacology
    Species: Mouse
    Sample Types: Serum
  11. Expression of cytokine and Apoptosis-Associated genes in mice bone Marrow-Derived Macrophages stimulated with Brucella recombinant type IV secretion effectors
    Authors: Li, Z;Wang, S;Han, J;Shi, C;Xi, L;Cui, Y;Zhang, H;
    Cytokine
    Species: Mouse
    Sample Types: Cell Culture Supernates
  12. Caspase-4/11 promotes hyperlipidemia and chronic kidney disease-accelerated vascular inflammation by enhancing trained immunity
    Authors: Sun, Y;Lu, Y;Liu, L;Saaoud, F;Shao, Y;Xu, K;Drummer Iv, C;Cueto, R;Shan, H;Jiang, X;Zhao, H;Wang, H;Yang, X;
    JCI insight
    Species: Transgenic Mouse
    Sample Types: Plasma
  13. In vivo magnetogenetics for cell-type-specific targeting and modulation of brain circuits
    Authors: Choi, SH;Shin, J;Park, C;Lee, JU;Lee, J;Ambo, Y;Shin, W;Yu, R;Kim, JY;Lah, JD;Shin, D;Kim, G;Noh, K;Koh, W;Lee, CJ;Lee, JH;Kwak, M;Cheon, J;
    Nature nanotechnology
    Species: Transgenic Mouse
    Sample Types: Tissue Homogenates
  14. Intraductal photothermal ablation: a noninvasive approach for early breast cancer treatment and prevention
    Authors: Liu, J;Huang, B;Rao, Y;Guo, L;Cai, C;Gao, D;Kong, D;Wang, G;Xiong, Y;Cui, R;Zhang, M;Chen, C;
    Theranostics
    Species: Mouse
    Sample Types: Tissue Homogenates
  15. Geranylgeranylacetone mitigates sepsis-associated intestinal injury through CHIP-dependent anti-inflammation and anti-oxidative effect
    Authors: Liu, X;Liu, Y;Su, X;Jiang, L;Tang, G;Wang, Y;
    International immunopharmacology
    Species: Mouse
    Sample Types: Tissue Homogenates
  16. Augmented antitumor immune responses of HER2-targeted pyroptotic induction by long-lasting recombinant immunopyroptotins
    Authors: Xing, Y;Zhang, F;Yang, T;Yin, C;Yang, A;Yan, B;Zhao, J;
    Heliyon
    Species: Mouse
    Sample Types: Plasma, Tissue Homogenates
  17. Insights into the effect of guanylate-binding protein 1 on the survival of Brucella intracellularly
    Authors: Li, Z;Wang, S;Han, J;Yang, G;Xi, L;Zhang, C;Cui, Y;Yin, S;Zhang, Y;Zhang, H;
    Veterinary microbiology
    Species: Mouse
    Sample Types: Cell Culture Supernates
  18. Mesenchymal stem cell-derived exosomes overexpressing SRC-3 protect mice from cerebral ischemia by inhibiting ferroptosis
    Authors: Deng, M;Hou, Y;Liu, J;He, J;Lan, Z;Xiao, H;
    Brain research bulletin
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. Oral TNF-? siRNA delivery via milk-derived exosomes for effective treatment of inflammatory bowel disease
    Authors: Han, G;Kim, H;Jang, H;Kim, ES;Kim, SH;Yang, Y;
    Bioactive materials
    Species: Mouse
    Sample Types: Bacteria
  20. Platelet-rich plasma-derived extracellular vesicles inhibit NF-?B/NLRP3 pathway-mediated pyroptosis in intervertebral disc degeneration via the MALAT1/microRNA-217/SIRT1 axis
    Authors: Tao, X;Xue, F;Xu, J;Wang, W;
    Cellular signalling
    Species: Mouse
    Sample Types:
  21. A Novel Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-Kappa B Activation Pathway is Involved in the Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemia-Reperfusion Lung Injury
    Authors: Miyashita, Y;Kanou, T;Fukui, E;Matsui, T;Kimura, T;Ose, N;Funaki, S;Shintani, Y;
    Transplantation proceedings
    Species: Mouse
    Sample Types: Plasma
  22. SELENOK-dependent CD36 palmitoylation regulates microglial functions and A? phagocytosis
    Authors: Ouyang, P;Cai, Z;Peng, J;Lin, S;Chen, X;Chen, C;Feng, Z;Wang, L;Song, G;Zhang, Z;
    Redox biology
    Species: Mouse
    Sample Types: Bacteria
  23. A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome
    Authors: Song, J;Wu, J;Robichaux, DJ;Li, T;Wang, S;Arredondo Sancristobal, MJ;Dong, B;Dobrev, D;Karch, J;Thomas, SS;Li, N;
    Cells
    Species: Mouse
    Sample Types: Serum
  24. RAGE in circulating immune cells is fundamental for hippocampal inflammation and cognitive decline in a mouse model of latent chronic inflammation
    Authors: Ye, D;Miyoshi, A;Ushitani, T;Kadoya, M;Igeta, M;Konishi, K;Shoji, T;Yasuda, K;Kitaoka, S;Yagi, H;Kuroda, E;Yamamoto, Y;Cheng, J;Koyama, H;
    Brain, behavior, and immunity
    Species: Transgenic Mouse
    Sample Types: Serum
  25. Enhancement of Immune Functions by Limosilactobacillus reuteri KBL346: In Vitro and In Vivo Studies
    Authors: Park, C;Ji, SY;Hwangbo, H;Shin, SY;Kim, MY;Lee, K;Kim, DH;Cho, BR;Lee, H;Choi, YH;You, HJ;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Serum
  26. Berberine Mediates the Production of Butyrate to Ameliorate Cerebral Ischemia via the Gut Microbiota in Mice
    Authors: Duan, H;Hu, J;Deng, Y;Zou, J;Ding, W;Peng, Q;Duan, R;Sun, J;Zhu, J;
    Nutrients
    Species: Mouse
    Sample Types: Tissue Homogenates
  27. The tetrapeptide sequence of IL-18 and IL-1? regulates their recruitment and activation by inflammatory caspases
    Authors: Exconde, PM;Hernandez-Chavez, C;Bourne, CM;Richards, RM;Bray, MB;Lopez, JL;Srivastava, T;Egan, MS;Zhang, J;Yoo, W;Shin, S;Discher, BM;Taabazuing, CY;
    Cell reports
    Species: Mouse
    Sample Types: Cell Culture Supernates
  28. Isobavachin, a main bioavailable compound in Psoralea corylifolia, alleviates lipopolysaccharide-induced inflammatory responses in macrophages and zebrafish by suppressing the MAPK and NF-?B signaling pathways
    Authors: Chung, YC;Song, SJ;Lee, A;Jang, CH;Kim, CS;Hwang, YH;
    Journal of ethnopharmacology
    Species: Mouse
    Sample Types: Cell Culture Supernates
  29. Arabinose confers protection against intestinal injury by improving integrity of intestinal mucosal barrier
    Authors: Xu, M;Shi, F;Gao, Y;Han, S;Huang, C;Hou, Q;Wen, X;Wang, B;Zhu, Z;Zou, L;Xiong, M;Dong, W;Tan, J;
    International immunopharmacology
    Species: Mouse
    Sample Types: Serum, Tissue Homogenates
  30. METTL3-mediated N6-methyladenosine modification stimulates mitochondrial damage and ferroptosis of kidney tubular epithelial cells following acute kidney injury by modulating the stabilization of MDM2-p53-LMNB1 axis
    Authors: Hu, C;Zhang, B;Zhao, S;
    European journal of medicinal chemistry
    Species: Mouse
    Sample Types: Serum, Tissue Homogenates
  31. Synthesis and characterization of piperic acid conjugates with homochiral and heterochiral dipeptides containing phenylalanine and their application in skin cancer
    Authors: Ur Rahim, J;Faheem, MM;Nawaz, S;Goswami, A;Rai, R;
    Peptides
    Species: Mouse
    Sample Types: Serum
  32. NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis
    Authors: Chen, WC;Yu, WK;Su, VY;Hsu, HS;Yang, KY;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Tissue Homogenates
  33. Hsp70 ameliorates sleep deprivation-induced anxiety-like behavior and cognitive impairment in mice
    Authors: Kang, Z;Lin, Y;Su, C;Li, S;Xie, W;Wu, X;
    Brain research bulletin
    Species: Mouse
    Sample Types: Tissue Homogenates
  34. Research of STEAP3 interaction with Rab7A and RACK1 to modulate the MAPK and JAK/STAT signaling in Osteoarthritis
    Authors: Sun, C;Peng, S;Lv, Z;Guo, T;Zhang, L;
    International immunopharmacology
    Species: Rat
    Sample Types: Cell Culture Supernates
  35. Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p
    Authors: Wang, C;Feng, L;Zhu, L;Wu, L;Chen, B;Cui, C;Yang, M;Gao, Y;Jiang, P;
    Cell death & disease
    Species: Mouse
    Sample Types: Extracellular Vesicles
  36. Mycobacterium tuberculosis carrying the rifampicin drug-resistance-conferring rpoB mutation H445Y is associated with suppressed immunity through type I interferons
    Authors: Bobba, S;Howard, NC;Das, S;Ahmed, M;Tang, L;Thirunavukkarasu, S;Larsen, MH;Mathema, B;Divangahi, M;Khader, SA;
    mBio
    Species: Mouse
    Sample Types: Cell Culture Supernates, Tissue Homogenates
  37. Fucoxanthin Ameliorates Sepsis via Modulating Microbiota by Targeting IRF3 Activation
    Authors: Su, J;Guan, B;Su, Q;Hu, S;Wu, S;Tong, Z;Zhou, F;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Tissue Homogenates
  38. Low‑dose ionizing radiation attenuates high glucose‑induced hepatic apoptosis and immune factor release via modulation of a miR‑155‑SOCS1 axis
    Authors: Fan, H;Liu, S;Jiao, B;Liang, X;
    Molecular medicine reports
    Species: Mouse
    Sample Types: Cell Culture Supernates
  39. Dihydroquercetin (DHQ) ameliorates LPS-induced acute lung injury by regulating macrophage M2 polarization through IRF4/miR-132-3p/FBXW7 axis
    Authors: Li, C;Liu, J;Zhang, C;Cao, L;Zou, F;Zhang, Z;
    Pulmonary pharmacology & therapeutics
    Species: Mouse
    Sample Types: Tissue Homogenates
  40. NLRC5 Deficiency Reduces LPS-Induced Microglial Activation via Inhibition of NF-?B Signaling and Ameliorates Mice's Depressive-like Behavior
    Authors: Sun, C;Shen, Y;Liu, P;Shen, Y;Hu, Y;Li, P;Zhang, Y;Miao, F;Zhang, J;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Cell Culture Supernates
  41. The cGAS-STING-YY1 axis accelerates progression of neurodegeneration in a mouse model of Parkinson's disease via LCN2-dependent astrocyte senescence
    Authors: Jiang, SY;Tian, T;Yao, H;Xia, XM;Wang, C;Cao, L;Hu, G;Du, RH;Lu, M;
    Cell death and differentiation
    Species: Mouse
    Sample Types: Cell Culture Supernates, Tissue Homogenates
  42. JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders
    Authors: Ambrus-Aikelin, G;Takeda, K;Joetham, A;Lazic, M;Povero, D;Santini, AM;Pranadinata, R;Johnson, CD;McGeough, MD;Beasley, FC;Stansfield, R;McBride, C;Trzoss, L;Hoffman, HM;Feldstein, AE;Stafford, JA;Veal, JM;Bain, G;Gelfand, EW;
    Scientific reports
    Species: Mouse
    Sample Types: Plasma
  43. A Novel Therapeutic Formulation for the Improved Treatment of Indian Red Scorpion (Mesobuthus tamulus) Venom-Induced Toxicity-Tested in Caenorhabditis elegans and Rodent Models
    Authors: Das, B;Madhubala, D;Mahanta, S;Patra, A;Puzari, U;Khan, MR;Mukherjee, AK;
    Toxins
    Species: Mouse
    Sample Types: Plasma
  44. Aloe-Emodin Ameliorates Cecal Ligation and Puncture-Induced Sepsis
    Authors: Su, J;Chen, S;Xiao, J;Feng, Z;Hu, S;Su, Q;Chen, Q;Chen, D;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Cell Culture Supernates, Serum, Tissue Homogenates
  45. Cold-induced adaptive thermogenesis is impaired by exposure of Asian sand dust in mice
    Authors: Bagon, BB;Lee, J;Matienzo, ME;Lee, SJ;Pak, SW;Kim, K;Lee, J;Lee, CM;Shin, IS;Moon, C;Park, MJ;Kim, DI;
    Journal of thermal biology
    Species: Mouse
    Sample Types: BALF
  46. Glutathione trisulfide prevents lipopolysaccharide-induced retinal inflammation via inhibition of proinflammatory cytokine production in glial cells
    Authors: Tawarayama, H;Umeki, K;Inoue-Yanagimachi, M;Takahashi, N;Hasegawa, H;Himori, N;Tsuda, S;Kunikata, H;Akaike, T;Nakazawa, T;
    Scientific reports
    Species: Mouse
    Sample Types: Cell Culture Supernates
  47. Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice
    Authors: Schwarz, MM;Ganaie, SS;Feng, A;Brown, G;Yangdon, T;White, JM;Hoehl, RM;McMillen, CM;Rush, RE;Connors, KA;Cui, X;Leung, DW;Egawa, T;Amarasinghe, GK;Hartman, AL;
    Science advances
    Species: Mouse
    Sample Types: Tissue Homogenates
  48. Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages
    Authors: Lin, JB;Mora, A;Wang, TJ;Santeford, A;Usmani, D;Ligon, MM;Mysorekar, IU;Apte, RS;
    mBio
    Species: Mouse
    Sample Types: Cell Culture Supernates
  49. Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells
    Authors: Jadi, PK;Dave, A;Issa, R;Tabbasum, K;Okurowska, K;Samarth, A;Urwin, L;Green, LR;Partridge, LJ;MacNeil, S;Garg, P;Monk, PN;Roy, S;
    The ocular surface
    Species: Mouse
    Sample Types: Tissue Homogenates
  50. Anti-inflammatory effects of Allium cepa L. peel extracts via inhibition of JAK-STAT pathway in LPS-stimulated RAW264.7 cells
    Authors: Lee, HS;Kwon, YJ;Seo, EB;Kim, SK;Lee, H;Lee, JT;Chang, PS;Choi, YJ;Lee, SH;Ye, SK;
    Journal of ethnopharmacology
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. Leucine zipper protein 1 prevents doxorubicin-induced cardiotoxicity in mice
    Authors: Fan, D;Jin, Z;Cao, J;Li, Y;He, T;Zhang, W;Peng, L;Liu, H;Wu, X;Chen, M;Fan, Y;He, B;Yu, W;Wang, H;Hu, X;Lu, Z;
    Redox biology
    Species: Mouse, Transgenic Mouse
    Sample Types: Tissue Homogenates
  52. Qinzhu Liangxue inhibits IL-6-induced hyperproliferation and inflammation in HaCaT cells by regulating METTL14/SOCS3/STAT3 axis
    Authors: Chen, Y;Miao, X;Xiang, Y;Kuai, L;Ding, X;Ma, T;Li, B;Fan, B;
    Journal of ethnopharmacology
    Species: Mouse
    Sample Types: Serum
  53. Cardiomyocyte peroxisome proliferator-activated receptor ? prevents septic cardiomyopathy via improving mitochondrial function
    Authors: Zhu, XX;Wang, X;Jiao, SY;Liu, Y;Shi, L;Xu, Q;Wang, JJ;Chen, YE;Zhang, Q;Song, YT;Wei, M;Yu, BQ;Fielitz, J;Gonzalez, FJ;Du, J;Qu, AJ;
    Acta pharmacologica Sinica
    Species: Mouse
    Sample Types: Plasma
  54. Amelioration of Murine Colitis by Attenuated Salmonella choleraesuis Encoding Interleukin-19
    Authors: Chen, SY;Chu, CT;Yang, ML;Lin, JD;Wang, CT;Lee, CH;Lin, IC;Shiau, AL;Ling, P;Wu, CL;
    Microorganisms
    Species: Mouse
    Sample Types: Tissue Homogenates
  55. Antidiabetic and Immunoregulatory Activities of Extract of Phyllanthus emblica L. in NOD with Spontaneous and Cyclophosphamide-Accelerated Diabetic Mice
    Authors: Lin, CH;Kuo, YH;Shih, CC;
    International journal of molecular sciences
    Species: Mouse
    Sample Types:
  56. Parthenolide targets NLRP3 to treat inflammasome-related diseases
    Authors: Liu, L;Feng, L;Gao, J;Hu, J;Li, A;Zhu, Y;Zhang, C;Qiu, B;Shen, Z;
    International immunopharmacology
    Species: Mouse
    Sample Types: Cell Culture Supernates, Serum
  57. Endosomal trafficking of two-pore K+ efflux channel TWIK2 to plasmalemma mediates NLRP3 inflammasome activation and inflammatory injury
    Authors: Huang, LS;Anas, M;Xu, J;Zhou, B;Toth, PT;Krishnan, Y;Di, A;Malik, AB;
    eLife
    Species: Mouse
    Sample Types: Cell Culture Supernates
  58. LPS-induced mitochondrial dysfunction regulates innate immunity activation and alpha-synuclein oligomerization in Parkinson's disease
    Authors: AR Esteves, DF Silva, D Banha, E Candeias, B Guedes, SM Cardoso
    Redox Biology, 2023-04-25;63(0):102714.
    Species: Mouse
    Sample Types: Cell Lysates
  59. An IL-6/STAT3/MR/FGF21 axis mediates heart-liver cross-talk after myocardial infarction
    Authors: JY Sun, LJ Du, XR Shi, YY Zhang, Y Liu, YL Wang, BY Chen, T Liu, H Zhu, Y Liu, CC Ruan, Z Gan, H Ying, Z Yin, PJ Gao, X Yan, RG Li, SZ Duan
    Science Advances, 2023-04-05;9(14):eade4110.
    Species: Mouse
    Sample Types: Plasma
  60. Novel neuroendocrine role of gamma-aminobutyric acid and gastrin releasing peptide in the host response to influenza infection
    Authors: K Ann Shirey, W Lai, M Sunday, F Cuttitta, J Cg Blanco, SN Vogel
    Mucosal Immunology, 2023-03-24;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  61. Salidroside attenuates lipopolysaccharide-induced neuroinflammation and cognitive impairment in septic encephalopathy mice
    Authors: L Xiao, L Li, J Huang, Y Luan, J Pan, Y Gai, Z Xu
    International immunopharmacology, 2023-03-20;117(0):109975.
    Species: Mouse
    Sample Types: Serum
  62. Honokiol reduces fungal burden and ameliorate inflammation lesions of Aspergillus fumigatus keratitis via Dectin-2 down-regulation
    Authors: L Zhan, X Tian, J Lin, Y Zhang, H Zheng, X Peng, G Zhao
    International immunopharmacology, 2023-03-16;118(0):109849.
    Species: Mouse
    Sample Types: Cell culture supernate
  63. Increased hepatic interleukin-1, arachidonic acid, and reactive oxygen species mediate the protective potential of peptides shared by gut cysteine peptidases against Schistosoma mansoni infection in mice
    Authors: H Tallima, R El Ridi
    PloS Neglected Tropical Diseases, 2023-03-15;17(3):e0011164.
    Species: Mouse
    Sample Types: Tissue Homogenates
  64. Mitochondrial calcium uptake 3 mitigates cerebral amyloid angiopathy-related neuronal death and glial inflammation by reducing mitochondrial dysfunction
    Authors: G Zhou, Q Ye, Y Xu, B He, L Wu, G Zhu, J Xie, L Yao, Z Xiao
    International immunopharmacology, 2023-03-04;117(0):109614.
    Species: Mouse
    Sample Types: Tissue Homogenates
  65. Novel NF-kappaB reporter mouse for the non-invasive monitoring of inflammatory diseases
    Authors: SY Park, MW Kim, JH Kang, HJ Jung, JH Hwang, SJ Yang, JK Woo, Y Jeon, H Lee, YS Yoon, JK Seong, SH Oh
    Scientific Reports, 2023-03-02;13(1):3556.
    Species: Mouse
    Sample Types: Serum
  66. SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice
    Authors: FL Fontes-Dan, GG Fernandes, EG Gutman, EV De Lima, LS Antonio, MB Hammerle, HP Mota-Arauj, LC Colodeti, SMB Araújo, GM Froz, TN da Silva, LA Duarte, AL Salvio, KL Pires, LAA Leon, CCF Vasconcelo, L Romão, LEB Savio, JL Silva, R da Costa, JR Clarke, AT Da Poian, SV Alves-Leon, GF Passos, CP Figueiredo
    Cell Reports, 2023-02-17;42(3):112189.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  67. Exosome-Based Delivery of Super-Repressor IkappaBalpha Alleviates Alcohol-Associated Liver Injury in Mice
    Authors: HH Kim, YR Shim, SE Choi, TE Falana, JK Yoo, SH Ahn, M Park, H Seo, C Choi, WI Jeong
    Pharmaceutics, 2023-02-14;15(2):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  68. Thymosin Beta 4 Inhibits LPS and ATP-Induced Hepatic Stellate Cells via the Regulation of Multiple Signaling Pathways
    Authors: J Choi, Y Cho, H Choi, S Lee, H Han, J Lee, J Kwon
    International Journal of Molecular Sciences, 2023-02-08;24(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  69. ATF5 Attenuates the Secretion of Pro-Inflammatory Cytokines in Activated Microglia
    Authors: J Zhu, MJ Lee, JH An, E Oh, W Chung, JY Heo
    International Journal of Molecular Sciences, 2023-02-07;24(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  70. Anti-inflammatory effect and signaling mechanism of 8-shogaol and 10-shogaol in a dextran sodium sulfate-induced colitis mouse model
    Authors: HR Kim, EM Noh, SY Kim
    Heliyon, 2023-01-05;9(1):e12778.
    Species: Mouse
    Sample Types: Serum
  71. A�ai Berry Administration Promotes Wound Healing through Wnt/beta-Catenin Pathway
    Authors: L Interdonat, Y Marino, GA Franco, A Arangia, R D'Amico, R Siracusa, M Cordaro, D Impellizze, R Fusco, S Cuzzocrea, RD Paola
    International Journal of Molecular Sciences, 2023-01-03;24(1):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  72. Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice
    Authors: YH Kwon, S Banskota, H Wang, L Rossi, JA Grondin, SA Syed, Y Yousefi, JD Schertzer, KM Morrison, MG Wade, AC Holloway, MG Surette, GR Steinberg, WI Khan
    Nature Communications, 2022-12-20;13(1):7617.
    Species: Mouse
    Sample Types: Whole Tissue
  73. The Effects of Synthetic SREBP-1 and PPAR-gamma Decoy Oligodeoxynucleotide on Acne-like Disease In Vivo and In Vitro via Lipogenic Regulation
    Authors: H Gu, HJ An, MG Gwon, S Bae, CC Zouboulis, KK Park
    Biomolecules, 2022-12-12;12(12):.
    Species: Mouse
    Sample Types: Serum
  74. Inflammation promotes synucleinopathy propagation
    Authors: TK Kim, EJ Bae, BC Jung, M Choi, SJ Shin, SJ Park, JT Kim, MK Jung, A Ulusoy, MY Song, JS Lee, HJ Lee, DA Di Monte, SJ Lee
    Experimental & Molecular Medicine, 2022-12-06;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  75. Aberrant expression and localization of the RAP1 shelterin protein contribute to age-related phenotypes
    Authors: AJ Stock, RA McDevitt, C Puligilla, Y Wang, Y Zhang, K Wang, C Sun, KG Becker, E Lehrmann, WH Wood, Y Gong, M Aqdas, MH Sung, V Hoffmann, C Liu, M Gorospe, L Harrington, L Ferrucci, Y Liu
    PloS Genetics, 2022-11-28;18(11):e1010506.
    Species: Mouse
    Sample Types: Tissue Homogenates
  76. Efficacy of Clinically Used PARP Inhibitors in a Murine Model of Acute Lung Injury
    Authors: V Martins, SS Santos, LOCP Rodrigues, R Salomao, L Liaudet, C Szabo
    Cells, 2022-11-26;11(23):.
    Species: Mouse
    Sample Types: BALF
  77. GPSM1 impairs metabolic homeostasis by controlling a pro-inflammatory pathway in macrophages
    Authors: J Yan, Y Zhang, H Yu, Y Zong, D Wang, J Zheng, L Jin, X Yu, C Liu, Y Zhang, F Jiang, R Zhang, X Fang, T Xu, M Li, J Di, Y Lu, X Ma, J Zhang, W Jia, C Hu
    Nature Communications, 2022-11-25;13(1):7260.
    Species: Mouse
    Sample Types: Serum
  78. RasGRP1 promotes the acute inflammatory response and restricts inflammation-associated cancer cell growth
    Authors: C Wang, X Li, B Xue, C Yu, L Wang, R Deng, H Liu, Z Chen, Y Zhang, S Fan, C Zuo, H Sun, H Zhu, J Wang, S Tang
    Nature Communications, 2022-11-16;13(1):7001.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  79. Attenuation of hepatic fibrosis by p-Coumaric acid via modulation of NLRP3 inflammasome activation in C57BL/6 mice
    Authors: TMT Truong, SH Seo, S Chung, I Kang
    The Journal of nutritional biochemistry, 2022-11-15;0(0):109204.
    Species: Mouse
    Sample Types: Plasma
  80. Cynapanoside A exerts protective effects against obesity-induced diabetic nephropathy through ameliorating TRIM31-mediated inflammation, lipid synthesis and fibrosis
    Authors: J Luo, J Tan, J Zhao, L Wang, J Liu, X Dai, Y Sun, Q Kuang, J Hui, J Chen, G Kuang, S Chen, Y Wang, C Ge, M Xu
    International immunopharmacology, 2022-11-11;113(0):109395.
    Species: Mouse
    Sample Types: Serum
  81. Motor neuron survival is associated with reduced neuroinflammation and increased autophagy after brachial plexus avulsion injury in aldose reductase-deficient mice
    Authors: K Zhong, Y Huang, PLM Zilundu, Y Wang, Y Zhou, G Yu, R Fu, SK Chung, Y Tang, X Cheng, L Zhou
    Journal of Neuroinflammation, 2022-11-09;19(1):271.
    Species: Mouse
    Sample Types: Tissue Homogenates
  82. Ubiquitin?specific protease 8 ameliorates lipopolysaccharide?induced spleen injury via suppression of NF?kappaB and MAPK signaling pathways
    Authors: W Bi, J Zhang, Z Zeng, R Zhou, J Zhao, W Yan, L Wang, X Li, L Zhu
    Molecular Medicine Reports, 2022-11-02;26(6):.
    Species: Mouse
    Sample Types: Serum
  83. Macrophage Sprouty4 deficiency diminishes sepsis-induced acute lung injury in mice
    Authors: R Chen, C Cao, H Liu, W Jiang, R Pan, H He, K Ding, Q Meng
    Redox Biology, 2022-10-22;58(0):102513.
    Species: Mouse
    Sample Types: BALF
  84. Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy
    Authors: ZM Howard, CK Gomatam, CP Rabolli, J Lowe, AB Piepho, SS Bansal, F Accornero, JA Rafael-For
    JCI Insight, 2022-10-10;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  85. Hepatocyte phosphatase DUSP22 mitigates NASH-HCC progression by targeting FAK
    Authors: C Ge, J Tan, X Dai, Q Kuang, S Zhong, L Lai, C Yi, Y Sun, J Luo, C Zhang, L Zhu, B Wang, M Xu
    Oncogene, 2022-10-08;13(1):5945.
    Species: Mouse
    Sample Types: Serum
  86. Vathasura Kudineer, an Andrographis based polyherbal formulation exhibits immunomodulation and inhibits chikungunya virus (CHIKV) under in-vitro conditions
    Authors: A Hasan, S Devi Ms, G Sharma, V Narayanan, P Sathiyaraj, S Vinayak, S Sunil
    Journal of ethnopharmacology, 2022-09-29;0(0):115762.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  87. Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or KATP channels inhibitors
    Authors: M Shayan, F Eslami, A Amanlou, S Solaimania, N Rahimi, A Rashidian, S Ejtemaei-M, M Ghasemi, AR Dehpour
    Toxicology and Applied Pharmacology, 2022-09-23;454(0):116254.
    Species: Mouse
    Sample Types: Tissue Homogenates
  88. Targeting the succinate receptor effectively inhibits periodontitis
    Authors: Y Guo, F Xu, SC Thomas, Y Zhang, B Paul, S Sakilam, S Chae, P Li, C Almeter, AR Kamer, P Arora, DT Graves, D Saxena, X Li
    Cell Reports, 2022-09-20;40(12):111389.
    Species: Mouse
    Sample Types: Serum
  89. Modification of the immune response by bacteriophages alters methicillin-resistant Staphylococcus aureus infection
    Authors: T Suda, T Hanawa, M Tanaka, Y Tanji, K Miyanaga, S Hasegawa-I, K Shirato, T Kizaki, T Matsuda
    Scientific Reports, 2022-09-19;12(1):15656.
    Species: Mouse
    Sample Types: Tissue Lysates
  90. Maternal high-fat diet promotes calcified atherosclerotic plaque formation in adult offspring by enhancing transformation of VSMCs to osteochondrocytic-like phenotype
    Authors: D Miyawaki, H Yamada, M Saburi, N Wada, S Motoyama, T Sugimoto, H Kubota, N Wakana, D Kami, T Ogata, S Matoba
    Heliyon, 2022-09-15;8(9):e10644.
    Species: Transgenic Mouse
    Sample Types: Serum
  91. Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis
    Authors: X Zhang, SK Misra, P Moitra, X Zhang, SJ Jeong, J Stitham, A Rodriguez-, A Park, YS Yeh, WE Gillanders, D Fan, A Diwan, J Cho, S Epelman, IJ Lodhi, D Pan, B Razani
    Autophagy, 2022-08-18;0(0):1-18.
    Species: Mouse
    Sample Types: Cell Culture Supenates
  92. Synthesis and NLRP3-Inflammasome Inhibitory Activity of the Naturally Occurring Velutone F and of Its Non-Natural Regioisomeric Chalconoids
    Authors: T De Ventura, M Perrone, S Missiroli, P Pinton, P Marchetti, G Strazzabos, G Turrin, D Illuminati, V Cristofori, A Fantinati, M Fabbri, C Giorgi, C Trapella, V Zanirato
    International Journal of Molecular Sciences, 2022-08-11;23(16):.
    Species: Mouse
    Sample Types: Plasma
  93. Sensitization of GSH synthesis by curcumin curtails acrolein-induced alveolar epithelial apoptosis via Keap1 cysteine conjugation: A randomized controlled trial and experimental animal model of pneumonitis
    Authors: E Hee Jo, J Eun Moon, M Han Chang, Y Jin Lim, J Hyun Park, S Hee Lee, Y Rae Cho, AE Cho, S Pil Pack, HW Kim, L Crowley, B Le, AB Nukhet, Y Chen, Y Zhong, J Zhao, Y Li, H Cha, J Hoon Pan, J Kyeom Kim, J Hyup Lee
    Journal of advanced research, 2022-06-27;0(0):.
    Species: Mouse
    Sample Types: Plasma
  94. Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction
    Authors: JK Sterling, B Baumann, S Foshe, A Voigt, S Guttha, A Alnemri, SJ McCright, M Li, RJ Zauhar, SR Montezuma, RJ Kapphahn, VRM Chavali, DA Hill, DA Ferrington, D Stambolian, RF Mullins, D Merrick, JL Dunaief
    Cell Reports, 2022-06-14;39(11):110942.
    Species: Mouse
    Sample Types: Serum
  95. Gasdermin D Deficiency Limits the Transition of Atherosclerotic Plaques to an Inflammatory Phenotype in ApoE Knock-Out Mice
    Authors: P Puylaert, M Van Praet, F Vaes, CHG Neutel, L Roth, PJ Guns, GRY De Meyer, W Martinet
    Biomedicines, 2022-05-19;10(5):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  96. The Alleviation of Gut Microbiota-Induced Depression and Colitis in Mice by Anti-Inflammatory Probiotics NK151, NK173, and NK175
    Authors: JW Yoo, YJ Shin, X Ma, YH Son, HM Jang, CK Lee, DH Kim
    Nutrients, 2022-05-16;14(10):.
    Species: Mouse
    Sample Types: Tissue Lysates
  97. MicroRNA-299a-5p Protects against Spinal Cord Injury through Activating AMPK Pathway
    Authors: ZZ Zhang, SY Xian, C Bao, F Chen
    Oxidative Medicine and Cellular Longevity, 2022-05-13;2022(0):8659587.
    Species: Mouse
    Sample Types: Tissue Homogenates
  98. Hypercoagulability Impairs Plaque Stability in Diabetes-Induced Atherosclerosis
    Authors: S Ambreen, S Fatima, A Elwakiel, R Rana, K Singh, A Gupta, D Gupta, H Khawaja, J Manoharan, C Besler, U Laufs, S Kohli, B Isermann, K Shahzad
    Nutrients, 2022-05-10;14(10):.
    Species: Mouse
    Sample Types: Plasma
  99. High-fructose corn syrup promotes proinflammatory Macrophage activation via ROS-mediated NF-kappaB signaling and exacerbates colitis in mice
    Authors: L Wang, T Ji, Y Yuan, H Fu, Y Wang, S Tian, J Hu, L Wang, Z Wang
    International immunopharmacology, 2022-05-06;109(0):108814.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  100. TH17 cells promote CNS inflammation by sensing danger signals via Mincle
    Authors: Q Zhang, W Liu, H Wang, H Zhou, K Bulek, X Chen, CJ Zhang, J Zhao, R Zhang, C Liu, Z Kang, RA Bermel, G Dubyak, DW Abbott, TS Xiao, LE Nagy, X Li
    Nature Communications, 2022-05-03;13(1):2406.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  101. Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation
    Authors: LK Billingham, JS Stoolman, K Vasan, AE Rodriguez, TA Poor, M Szibor, HT Jacobs, CR Reczek, A Rashidi, P Zhang, J Miska, NS Chandel
    Nature Immunology, 2022-04-28;0(0):.
    Species: Mouse
    Sample Types: Serum
  102. Amyloid-beta activates NLRP3 inflammasomes by affecting microglial immunometabolism through the Syk-AMPK pathway
    Authors: ES Jung, K Suh, J Han, H Kim, HS Kang, WS Choi, I Mook-Jung
    Aging Cell, 2022-04-27;0(0):e13623.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  103. Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation
    Authors: Y Wang, C Chen, J Chen, T Sang, H Peng, X Lin, Q Zhao, S Chen, T Eling, X Wang
    Redox Biology, 2022-04-27;52(0):102322.
    Species: Mouse
    Sample Types: Serum
  104. Renoprotective effects of ferric citrate in a mouse model of chronic kidney disease
    Authors: MR Hanudel, B Czaya, S Wong, G Jung, K Chua, B Qiao, V Gabayan, T Ganz
    Scientific Reports, 2022-04-23;12(1):6695.
    Species: Mouse
    Sample Types:
  105. Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues
    Authors: A Daghrery, JA Ferreira, J Xu, N Golafshan, D Kaigler, SB Bhaduri, J Malda, M Castilho, MC Bottino
    Bioactive materials, 2022-04-22;19(0):268-281.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  106. S-Acetyl-Glutathione Attenuates Carbon Tetrachloride-Induced Liver Injury by Modulating Oxidative Imbalance and Inflammation
    Authors: R Di Paola, S Modafferi, R Siracusa, M Cordaro, R D'Amico, ML Ontario, L Interdonat, AT Salinaro, R Fusco, D Impellizze, V Calabrese, S Cuzzocrea
    International Journal of Molecular Sciences, 2022-04-17;23(8):.
    Species: Mouse
    Sample Types: Serum
  107. Dynamic synovial fibroblasts are modulated by NBCn1 as a potential target in rheumatoid arthritis
    Authors: M Ji, HJ Ryu, HM Baek, DM Shin, JH Hong
    Experimental & Molecular Medicine, 2022-04-12;0(0):.
    Species: Mouse
    Sample Types: Plasma
  108. RANKL Impairs the TLR4 Pathway by Increasing TRAF6 and RANK Interaction in Macrophages
    Authors: RF Mota, PH Cavalcanti, MER Cezine, FS Matsuo, RJM Metzner, CA Oliveira d, KC Peronni, H Hayashi, M Shimamura, H Nakagami, MK Osako
    BioMed Research International, 2022-04-12;2022(0):7740079.
    Species: Human, Mouse, Transgenic Mouse
    Sample Types: Cell Culture Supernates
  109. SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell autonomous hippocampal neuronal death
    Authors: J Oh, WH Cho, E Barcelon, KH Kim, J Hong, SJ Lee
    Scientific Reports, 2022-03-31;12(1):5496.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  110. Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3beta-Nrf2 pathway
    Authors: K Huo, KG Ma, QY Guo, P Duan, J Xu
    International immunopharmacology, 2022-03-31;108(0):108718.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  111. Cucurbitacin E glucoside alleviates concanavalin A-induced hepatitis through enhancing SIRT1/Nrf2/HO-1 and inhibiting NF-?B/NLRP3 signaling pathways
    Authors: GA Mohamed, SRM Ibrahim, DS El-Agamy, WM Elsaed, A Sirwi, HZ Asfour, AE Koshak, SS Elhady
    Journal of ethnopharmacology, 2022-03-27;292(0):115223.
    Species: Mouse
    Sample Types: Tissue Homogenates
  112. Critical role of FPR1 in splenocyte migration into brain to worsen inflammation and ischemic brain injury in mice
    Authors: J Li, MD Chordia, Y Zhang, H Zong, D Pan, Z Zuo
    Theranostics, 2022-03-21;12(7):3024-3044.
    Species: Mouse
    Sample Types: Tissue Homogenates
  113. GSPE Protects against Bleomycin-Induced Pulmonary Fibrosis in Mice via Ameliorating Epithelial Apoptosis through Inhibition of Oxidative Stress
    Authors: OJ Sul, JH Kim, T Lee, KW Seo, HJ Cha, B Kwon, JJ Ahn, YS Cho, YM Oh, Y Jegal, SW Ra
    Oxidative Medicine and Cellular Longevity, 2022-03-20;2022(0):8200189.
    Species: Mouse
    Sample Types: Tissue Homogenates
  114. Pharmacological Inhibition of Glutaminase 1 Attenuates Alkali-Induced Corneal Neovascularization by Modulating Macrophages
    Authors: Y Feng, X Yang, J Huang, M Shen, L Wang, X Chen, Y Yuan, C Dong, X Ma, F Yuan
    Oxidative Medicine and Cellular Longevity, 2022-03-19;2022(0):1106313.
    Species: Mouse
    Sample Types: Protein
  115. Strongylocentrotus nudus Eggs Polysaccharide Enhances Macrophage Phagocytosis Against E.coli Infection by TLR4/STAT3 Axis
    Authors: X Tian, M Guo, X Zhang, L Guo, N Lan, Y Cheng, Y Han, M Wang, Z Peng, C Zhou, H Fan
    Frontiers in Pharmacology, 2022-03-17;13(0):807440.
    Species: Mouse
    Sample Types: Tissue Homogenates
  116. Cytokines and Neurodegeneration in Epileptogenesis
    Authors: P Wolinski, D Ksiazek-Wi, A Glabinski
    Brain sciences, 2022-03-12;12(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  117. Povidone iodine suppresses LPS-induced inflammation by inhibiting TLR4/MyD88 formation in airway epithelial cells
    Authors: SH Lee, MR Choi, J Chung, SH Choi, SK Park, YM Kim
    Scientific Reports, 2022-03-07;12(1):3681.
    Species: Mouse
    Sample Types: Nasal Lavage Fluid
  118. Serum Amyloid A1 Exacerbates Hepatic Steatosis via TLR4 Mediated NF-kappaB Signaling Pathway
    Authors: B Jiang, D Wang, Y Hu, W Li, F Liu, X Zhu, X Li, H Zhang, H Bai, Q Yang, X Yang, J Ben, Q Chen
    Molecular Metabolism, 2022-03-03;0(0):101462.
    Species: Mouse
    Sample Types: Plasma
  119. Fatty Acid Amide Hydrolase (FAAH) Inhibition Plays a Key Role in Counteracting Acute Lung Injury
    Authors: T Genovese, A Duranti, R D'Amico, R Fusco, D Impellizze, AF Peritore, R Crupi, E Gugliandol, S Cuzzocrea, R Di Paola, R Siracusa, M Cordaro
    International Journal of Molecular Sciences, 2022-03-03;23(5):.
    Species: Mouse
    Sample Types: Alveolar Fluid
  120. Kakonein restores hyperglycemia-induced macrophage digestion dysfunction through regulation of cathepsin B-dependent NLRP3 inflammasome activation
    Authors: D Lian, L Zhu, Y Yu, X Zhang, Y Lin, J Liu, R Han, Y Guo, D Cai, W Xiao, Y Chen, H He, D Xu, C Zheng, X Wang, Y Huang, Y Chen
    Journal of leukocyte biology, 2022-02-27;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  121. The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes
    Authors: M Xu, J Tan, W Dong, B Zou, X Teng, L Zhu, C Ge, X Dai, Q Kuang, S Zhong, L Lai, C Yi, T Tang, J Zhao, L Wang, J Liu, H Wei, Y Sun, Q Yang, Q Li, D Lou, L Hu, X Liu, G Kuang, J Luo, M Xiong, J Feng, C Zhang, B Wang
    Nature Communications, 2022-02-25;13(1):1052.
    Species: Mouse
    Sample Types: Serum
  122. Palmatine attenuates the doxorubicin-induced inflammatory response, oxidative damage and cardiomyocyte apoptosis
    Authors: D Cheng, P Liu, Z Wang
    International immunopharmacology, 2022-02-09;106(0):108583.
    Species: Mouse
    Sample Types: Serum
  123. Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1
    Authors: K Peukert, F Steinhagen, M Fox, C Feuerborn, S Schulz, B Seeliger, P Schuss, M Schneider, S Frede, A Sauer, C Putensen, E Latz, C Wilhelm, C Bode
    Respiratory Research, 2022-02-07;23(1):21.
    Species: Mouse
    Sample Types: BALF
  124. 2-Chlorodeoxyadenosine (Cladribine) preferentially inhibits the biological activity of microglial cells
    Authors: F Aybar, M Julia Pere, M Silvina Ma, M Eugenia Sa, M Marrodan, J María Pasq, J Correale
    International immunopharmacology, 2022-01-29;105(0):108571.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  125. Maternal P2X7 receptor inhibition prevents autism-like phenotype in male mouse offspring through the NLRP3-IL-1beta pathway
    Authors: D Szabó, P Tod, F Gölöncsér, V Román, B Lendvai, L Otrokocsi, B Sperlágh
    Brain, Behavior, and Immunity, 2022-01-20;0(0):.
    Species: Mouse
    Sample Types: Plasma
  126. Gasdermin D pores are dynamically regulated by local phosphoinositide circuitry
    Authors: AB Santa Cruz, KP Schnur, AB Malik, GCH Mo
    Nature Communications, 2022-01-10;13(1):52.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  127. Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies
    Authors: M Kamiya, F Mizoguchi, K Kawahata, D Wang, M Nishibori, J Day, C Louis, IP Wicks, H Kohsaka, S Yasuda
    Nature Communications, 2022-01-10;13(1):166.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  128. Liensinine alleviates high fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) through suppressing oxidative stress and inflammation via regulating TAK1/AMPK signaling
    Authors: L Liang, S Ye, R Jiang, X Zhou, J Zhou, S Meng
    International immunopharmacology, 2022-01-06;104(0):108306.
    Species: Mouse
    Sample Types: Serum
  129. Brain-specific TRAF7 deletion ameliorates traumatic brain injury by suppressing MEKK3-regulated glial inflammation and neuronal death
    Authors: Y Yuxiong, X Xujin, T Yi, C Ya, L Yujuan, H Shanshan, W Huiwen
    International immunopharmacology, 2021-12-23;103(0):108219.
    Species: Transgenic Mouse
    Sample Types: Tissue Homogenates
  130. Bruton's tyrosine kinase drives neuroinflammation and anxiogenic behavior in mouse models of stress
    Authors: S Ghosh, Z Mohammed, I Singh
    Journal of Neuroinflammation, 2021-12-11;18(1):289.
    Species: Mouse
    Sample Types: Tissue Homogenates
  131. Exercise Inhibits NLRP3 Inflammasome Activation in Obese Mice via the Anti-Inflammatory Effect of Meteorin-like
    Authors: HMA Javaid, NE Sahar, DL ZhuGe, JY Huh
    Cells, 2021-12-09;10(12):.
    Species: Mouse
    Sample Types: Plasma
  132. Targeting MicroRNA-485-3p Blocks Alzheimer's Disease Progression
    Authors: HS Koh, S Lee, HJ Lee, JW Min, T Iwatsubo, CE Teunissen, HJ Cho, JH Ryu
    International Journal of Molecular Sciences, 2021-12-04;22(23):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  133. Epac-2 ameliorates spontaneous colitis in Il-10-/- mice by protecting the intestinal barrier and suppressing NF-kappaB/MAPK signalling
    Authors: X Song, H Wen, L Zuo, Z Geng, J Nian, L Wang, Y Jiang, J Tao, Z Zhu, X Wu, Z Wang, X Zhang, L Yu, H Zhao, P Xiang, J Li, L Shen, J Hu
    Journal of Cellular and Molecular Medicine, 2021-12-03;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  134. Exercise-Induced Irisin Decreases Inflammation and Improves NAFLD by Competitive Binding with MD2
    Authors: W Zhu, NE Sahar, HMA Javaid, ES Pak, G Liang, Y Wang, H Ha, JY Huh
    Cells, 2021-11-25;10(12):.
    Species: Human
    Sample Types: Tissue Homogenates
  135. Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages
    Authors: X Ding, H Kambara, R Guo, A Kanneganti, M Acosta-Zal, J Li, F Liu, T Bei, W Qi, X Xie, W Han, N Liu, C Zhang, X Zhang, H Yu, L Zhao, F Ma, JR Köhler, HR Luo
    Nature Communications, 2021-11-18;12(1):6699.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  136. Chemical inducer of regucalcin attenuates lipopolysaccharide-induced inflammatory responses in pancreatic MIN6 beta-cells and RAW264.7 macrophages
    Authors: T Murata, K Hashimoto, S Kohno, C Takahashi, M Yamaguchi, C Ito, M Itoigawa, R Kojima, K Hikita, N Kaneda
    FEBS Open Bio, 2021-11-09;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Media
  137. Atractylenolide-III suppresses lipopolysaccharide-induced inflammation via downregulation of toll-like receptor 4 in mouse microglia
    Authors: E Novianti, G Katsuura, N Kawamura, A Asakawa, A Inui
    Heliyon, 2021-10-27;7(10):e08269.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  138. All?trans retinoic acid promotes macrophage phagocytosis and decreases inflammation via inhibiting CD14/TLR4 in acute lung injury
    Authors: S Li, Y Lei, J Lei, H Li
    Molecular Medicine Reports, 2021-10-22;24(6):.
    Species: Mouse
    Sample Types: Plasma
  139. A Novel Para-Amino Salicylic Acid Magnesium Layered Hydroxide Nanocomposite Anti-Tuberculosis Drug Delivery System with Enhanced in vitro Therapeutic and Anti-Inflammatory Properties
    Authors: B Saifullah, P Arulselvan, ME El Zowalat, WS Tan, S Fakurazi, TJ Webster, R Baby, MZ Hussein
    International Journal of Nanomedicine, 2021-10-15;16(0):7035-7050.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  140. Anti-fibrotic effect of Pycnogenol� in a polyhexamethylene guanidine-treated mouse model
    Authors: CM Park, HY Kim, D Jeon, YJ Shin, IH Kim, SJ Choi, KC Kim, K Lee, SH Kim, MS Kim
    Respiratory physiology & neurobiology, 2021-10-12;0(0):103802.
    Species: Mouse
    Sample Types: Tissue Homogenates
  141. Short-term effect of ligature-induced periodontitis on cardiovascular variability and inflammatory response in spontaneously hypertensive rats
    Authors: AB Ribeiro, TM da Silva, NN Santos-Jún, JA Castania, R Fazan, HC Salgado
    BMC Oral Health, 2021-10-11;21(1):515.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  142. Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment
    Authors: Y Wang, X Zhao, M Gao, X Wan, Y Guo, Y Qu, Y Chen, T Li, H Liu, M Jiang, F Wang, X Sun
    Cell Death & Disease, 2021-10-09;12(10):926.
    Species: Mouse
    Sample Types: Tissue Lysates
  143. Aerobic exercise inhibits inflammatory response in atherosclerosis via Sestrin1 protein
    Authors: Y Sun, Y Wu, Y Jiang, H Liu
    Experimental gerontology, 2021-10-08;155(0):111581.
    Species: Transgenic Mouse
    Sample Types: Cell Lysates
  144. Mechanism of chlorogenic acid in alveolar macrophage polarization in Klebsiella pneumoniae-induced pneumonia
    Authors: QR Li, SR Tan, L Yang, W He, L Chen, FX Shen, Z Wang, HF Wang
    Journal of leukocyte biology, 2021-09-29;0(0):.
    Species: Mouse
    Sample Types: BALF
  145. The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection
    Authors: NA Loeven, AI Perault, PA Cotter, CA Hodges, JD Schwartzma, TH Hampton, JB Bliska
    MBio, 2021-09-28;0(0):e0209821.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  146. NLRP3 Inflammasome Is Involved in Cocaine-Mediated Potentiation on Behavioral Changes in CX3CR1-Deficient Mice
    Authors: ML Guo, ET Chivero, SE Callen, S Buch
    Journal of personalized medicine, 2021-09-27;11(10):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  147. Antiatherosclerotic effect of dehydrocorydaline on ApoE-/- mice: inhibition of macrophage inflammation
    Authors: B Wen, YY Dang, SH Wu, YM Huang, KY Ma, YM Xu, XL Zheng, XY Dai
    Acta pharmacologica Sinica, 2021-09-22;0(0):.
    Species: Mouse
    Sample Types: Plasma
  148. TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage
    Authors: P Xu, C Tao, Y Zhu, G Wang, L Kong, W Li, R Li, J Li, C Zhang, L Wang, X Liu, W Sun, W Hu
    Journal of Neuroinflammation, 2021-08-30;18(1):188.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  149. Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF-kappaB Signaling
    Authors: Y Hou, X Xiao, W Yu, S Qi
    Journal of Immunology Research, 2021-08-24;2021(0):4754454.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  150. Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes
    Authors: S Lee, A Ishitsuka, T Kuroki, YH Lin, A Shibuya, T Hongu, Y Funakoshi, Y Kanaho, K Nagata, A Kawaguchi
    JCI Insight, 2021-08-23;6(16):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  151. Distinct pro-inflammatory properties of myeloid cell-derived apolipoprotein E2 and E4 in atherosclerosis promotion
    Authors: E Igel, A Haller, PR Wolfkiel, M Orr-Asman, A Jaeschke, DY Hui
    The Journal of Biological Chemistry, 2021-08-21;0(0):101106.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  152. Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors
    Authors: Y Zhou, J Hann, V Schenten, S Plançon, JL Bueb, F Tolle, S Bréchard
    International Journal of Molecular Sciences, 2021-08-17;22(16):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  153. Propofol Ameliorates Microglia Activation by Targeting MicroRNA-221/222-IRF2 Axis
    Authors: X Xiao, Y Hou, W Yu, S Qi
    Journal of Immunology Research, 2021-08-10;2021(0):3101146.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  154. DNA-Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice
    Authors: Y Koga, A Sotokawauc, Y Higashimot, Y Nishino, N Hashizume, T Kakuma, J Akiba, Y Tanaka, T Matsui, M Yagi, SI Yamagishi
    Oxidative Medicine and Cellular Longevity, 2021-08-07;2021(0):9932311.
    Species: Mouse
    Sample Types: Serum
  155. Aging and neuroinflammation: Changes in immune cell responses, axon integrity, and motor function in a viral model of progressive multiple sclerosis
    Authors: L Mestre, G Alonso, A Feliú, M Mecha, C Martín, LM Villar, C Guaza
    Aging Cell, 2021-08-06;0(0):e13440.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  156. Selective NF-kappaB inducing kinase inhibitor attenuates the onset of chronic periodontitis
    Authors: J Wang, S Wu, Z Li, L Liu, Y Pang, J Wei
    The international journal of biochemistry & cell biology, 2021-08-05;0(0):106052.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  157. Pirfenidone ameliorates silica-induced lung inflammation and fibrosis in mice by inhibiting the secretion of interleukin-17A
    Authors: ZJ Cao, Y Liu, Z Zhang, PR Yang, ZG Li, MY Song, XM Qi, ZF Han, JL Pang, BC Li, XR Zhang, HP Dai, J Wang, C Wang
    Acta pharmacologica Sinica, 2021-07-27;0(0):.
    Species: Mouse
    Sample Types: BALF
  158. Pore-forming alpha-hemolysin efficiently improves the immunogenicity and protective efficacy of protein antigens
    Authors: JT Zou, HM Jing, Y Yuan, LH Lei, ZF Chen, Q Gou, QS Xiong, XL Zhang, Z Zhao, XK Zhang, H Zeng, QM Zou, JY Zhang
    PloS Pathogens, 2021-07-21;17(7):e1009752.
    Species: Mouse
    Sample Types: Tissue Homogenates
  159. Gramine promotes functional recovery after spinal cord injury via ameliorating microglia activation
    Authors: X Lu, F Lu, J Yu, X Xue, H Jiang, L Jiang, Y Yang
    Journal of Cellular and Molecular Medicine, 2021-07-19;25(16):7980-7992.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  160. Network Pharmacological Analysis and Experimental Validation of the Mechanisms of Action of Si-Ni-San Against Liver Fibrosis
    Authors: S Wang, C Tang, H Zhao, P Shen, C Lin, Y Zhu, D Han
    Frontiers in Pharmacology, 2021-07-01;12(0):656115.
    Species: Mouse
    Sample Types: Serum
  161. Kakonein restores diabetes-induced endothelial junction dysfunction via promoting autophagy-mediated NLRP3 inflammasome degradation
    Authors: D Lian, J Liu, R Han, J Jin, L Zhu, Y Zhang, Y Huang, X Wang, S Xian, Y Chen
    Journal of Cellular and Molecular Medicine, 2021-06-27;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  162. Alterations in circulating extracellular vesicles underlie social stress-induced behaviors in mice
    Authors: S Sakamoto, D Mallah, DJ Medeiros, E Dohi, T Imai, IV Rose, K Matoba, X Zhu, A Kamiya, SI Kano
    FEBS Open Bio, 2021-06-24;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  163. Testosterone strongly enhances azoxymethane/dextran sulfate sodium-induced colorectal cancer development in C57BL/6 mice
    Authors: CH Song, N Kim, RH Nam, SI Choi, JE Yu, H Nho, E Shin, HN Lee, YJ Surh
    American journal of cancer research, 2021-06-15;11(6):3145-3162.
    Species: Mouse
    Sample Types: Tissue Homogenates
  164. LncRNA FENDRR Expression Correlates with Tumor Immunogenicity
    Authors: MC Munteanu, SN Sethuraman, MP Singh, J Malayer, A Ranjan
    Genes, 2021-06-10;12(6):.
    Species: Mouse
    Sample Types: Tumor Lysate
  165. Baicalin relieves Mycoplasma�pneumoniae infection?induced lung injury through regulating microRNA?221 to inhibit the TLR4/NF?&kappaB signaling pathway
    Authors: H Zhang, X Li, J Wang, Q Cheng, Y Shang, G Wang
    Molecular Medicine Reports, 2021-06-10;24(2):.
    Species: Mouse
    Sample Types: BALF
  166. The Fungal Metabolite (+)-Terrein Abrogates Ovariectomy-Induced Bone Loss and Receptor Activator of Nuclear Factor-&kappaB Ligand-Induced Osteoclastogenesis by Suppressing Protein Kinase-C &alpha/&betaII Phosphorylation
    Authors: K Sakaida, K Omori, M Nakayama, H Mandai, S Nakagawa, H Sako, C Kamei, S Yamamoto, H Kobayashi, S Ishii, M Ono, S Ibaragi, K Yamashiro, T Yamamoto, S Suga, S Takashiba
    Frontiers in Pharmacology, 2021-06-08;12(0):674366.
    Species: Mouse
    Sample Types: Serum
  167. Ginsenoside Rb1 prevents deoxynivalenol-induced immune injury via alleviating oxidative stress and apoptosis in mice
    Authors: SA Rajput, A Shaukat, IR Rajput, AA Kamboh, Z Iqbal, M Saeed, RW Akhtar, SAH Shah, MA Raza, A El Askary, MM Abdel-Daim, ZM Mohammedsa, RM Aljarai, MO Alamoudi, MA Alotaibi
    Ecotoxicology and environmental safety, 2021-05-28;220(0):112333.
    Species: Mouse
    Sample Types: Serum
  168. Anti?inflammatory effect of Chrysanthemum zawadskii, peppermint, Glycyrrhiza glabra herbal mixture in�lipopolysaccharide?stimulated RAW264.7 macrophages
    Authors: BO Cho, JY Shin, HJ Kang, JH Park, S Hao, F Wang, SI Jang
    Molecular Medicine Reports, 2021-05-26;24(1):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  169. V&gamma4 T cell-derived IL-17A is essential for amplification of inflammatory cascades in ischemic brain tissue after stroke
    Authors: L Lu, Y Wang, L Zhou, Y Li, X Zhang, X Hu, S Shi, W He
    International immunopharmacology, 2021-05-24;96(0):107678.
    Species: Mouse
    Sample Types: Tissue Homogenates
  170. Hydrogen sulfide attenuates renal I/R?induced activation of the inflammatory response and apoptosis via regulating Nrf2?mediated NLRP3 signaling pathway inhibition
    Authors: Y Su, Y Wang, M Liu, H Chen
    Molecular Medicine Reports, 2021-05-20;24(1):.
    Species: Mouse
    Sample Types: Serum
  171. IL-1&beta Impaired Diabetic Wound Healing by Regulating MMP-2 and MMP-9 through the p38 Pathway
    Authors: J Dai, J Shen, Y Chai, H Chen
    Mediators of Inflammation, 2021-05-18;2021(0):6645766.
    Species: Mouse
    Sample Types: Serum
  172. Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection
    Authors: T Lin, D Quellier, J Lamb, T Voisin, P Baral, F Bock, A Schönberg, R Mirchev, G Pier, I Chiu, M Gadjeva
    PloS Pathogens, 2021-05-06;17(5):e1009557.
    Species: Mouse
    Sample Types: Tissue Homogenates
  173. Augmenting ATG14 alleviates atherosclerosis and inhibits inflammation via promotion of autophagosome-lysosome fusion in macrophages
    Authors: H Zhang, S Ge, B Ni, K He, P Zhu, X Wu, Y Shao
    Autophagy, 2021-05-04;0(0):.
    Species: Mouse
    Sample Types: Serum
  174. Neuromodulatory effect of interleukin 1&beta in the dorsal raphe nucleus on individual differences in aggression
    Authors: A Takahashi, H Aleyasin, MA Stavarache, L Li, F Cathomas, LF Parise, HY Lin, CJ Burnett, A Aubry, ME Flanigan, A Brancato, C Menard, ML Pfau, V Kana, J Wang, GE Hodes, T Sasaki, MG Kaplitt, S Ogawa, BS McEwen, SJ Russo
    Molecular Psychiatry, 2021-04-30;0(0):.
    Species: Mouse
    Sample Types: Serum
  175. Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age
    Authors: N McGarry, CL Murray, S Garvey, A Wilkinson, L Tortorelli, L Ryan, L Hayden, D Healy, EW Griffin, E Hennessy, M Arumugam, DT Skelly, KJ Mitchell, C Cunningham
    Brain, Behavior, and Immunity, 2021-04-21;95(0):413-428.
    Species: Mouse
    Sample Types: Plasma
  176. Effects of S1PR2 antagonist on blood pressure and angiogenesis imbalance in preeclampsia rats
    Authors: T Zhang, D Guo, W Zheng, Q Dai
    Molecular Medicine Reports, 2021-04-21;23(6):.
    Species: Rat
    Sample Types: Serum
  177. A derivative of vitamin B3 applied several days after exposure reduces lethality of severely irradiated mice
    Authors: A Cheda, EM Nowosielsk, J Gebicki, A Marcinek, S Chlopicki, MK Janiak
    Scientific Reports, 2021-04-12;11(1):7922.
    Species: Mouse
    Sample Types: Serum
  178. Type 1 interferon mediates chronic stress-induced neuroinflammation and behavioral deficits via complement component 3-dependent pathway
    Authors: A Tripathi, C Whitehead, K Surrao, A Pillai, A Madeshiya, Y Li, H Khodadadi, AO Ahmed, G Turecki, B Baban, A Pillai
    Molecular Psychiatry, 2021-04-08;0(0):.
    Species: Mouse
    Sample Types: Serum
  179. Evaluation of the neurotoxic effects of engineered nanomaterials in C57BL/6J mice in 28-day oral exposure studies
    Authors: A Sofranko, T Wahle, HJ Heusinkvel, B Stahlmecke, M Dronov, D Pijnenburg, R Hilhorst, K Lamann, C Albrecht, RPF Schins
    Neurotoxicology, 2021-03-23;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  180. Exosomal circEhmt1 Released from Hypoxia-Pretreated Pericytes Regulates High Glucose-Induced Microvascular Dysfunction via the NFIA/NLRP3 Pathway
    Authors: L Ye, H Guo, Y Wang, Y Peng, Y Zhang, S Li, M Yang, L Wang
    Oxidative Medicine and Cellular Longevity, 2021-03-18;2021(0):8833098.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  181. ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation
    Authors: T Zhang, H Tsutsuki, W Islam, K Ono, K Takeda, T Akaike, T Sawa
    Redox Biology, 2021-03-10;41(0):101930.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  182. GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy
    Authors: Y Li, Y Yuan, ZX Huang, H Chen, R Lan, Z Wang, K Lai, H Chen, Z Chen, Z Zou, HB Ma, HY Lan, TW Mak, Y Xu
    Cell Death and Differentiation, 2021-03-04;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  183. Juglanin protects against high fat diet-induced renal injury by suppressing inflammation and dyslipidemia via regulating NF-&kappaB/HDAC3 signaling
    Authors: Q Li, C Ge, J Tan, Y Sun, Q Kuang, X Dai, S Zhong, C Yi, LF Hu, DS Lou, M Xu
    International immunopharmacology, 2021-03-02;95(0):107340.
    Species: Mouse
    Sample Types: Serum
  184. Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life
    Authors: MG Granja, LP Alves, M Leardini-T, ME Saul, LC Bortoni, FM de Moraes, EC Ferreira, BPT de Moraes, VZ da Silva, AFR Dos Santos, AR Silva, CF Gonçalves-, V Bambini-Ju, AS Weyrich, MT Rondina, GA Zimmerman, HC de Castro-
    Journal of Neuroinflammation, 2021-02-25;18(1):60.
    Species: Mouse
    Sample Types: Tissue Homogenates
  185. Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer's disease transgenic mouse model
    Authors: JKY Lau, M Tian, Y Shen, SF Lau, WY Fu, AKY Fu, NY Ip
    Scientific Reports, 2021-02-23;11(1):4359.
    Species: Mouse
    Sample Types: Tissue Homogenates
  186. Microglia-derived interleukin-10 accelerates post-intracerebral hemorrhage hematoma clearance by regulating CD36
    Authors: Q Li, X Lan, X Han, F Durham, J Wan, A Weiland, RC Koehler, J Wang
    Brain, Behavior, and Immunity, 2021-02-13;94(0):437-457.
    Species: Mouse
    Sample Types: Tissue Homogenates
  187. Alpha-1 antitrypsin deficiency impairs lung antibacterial immunity in mice
    Authors: L Ostermann, R Maus, J Stolper, L Schütte, K Katsarou, S Tumpara, A Pich, C Mueller, S Janciauski, T Welte, UA Maus
    JCI Insight, 2021-02-08;6(3):.
    Species: Mouse
    Sample Types: BALF
  188. SARS-CoV-2 spike protein S1 subunit induces pro-inflammatory responses via toll-like receptor 4 signaling in murine and human macrophages
    Authors: K Shirato, T Kizaki
    Heliyon, 2021-02-02;7(2):e06187.
    Species: Human, Mouse
    Sample Types: Cell Culture Supernates
  189. Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum
    Authors: L Liu, CZ Aron, CM Grable, A Robles, X Liu, Y Liu, NY Fatheree, JM Rhoads, JL Alcorn
    Scientific Reports, 2021-01-28;11(1):2593.
    Species: Mouse
    Sample Types: Tissue Homogenates
  190. Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner
    Authors: W Zhang, G Yin, H Zhao, H Ling, Z Xie, C Xiao, Y Chen, Y Lin, T Jiang, S Jin, J Wang, X Yang
    Cell Death & Disease, 2021-01-20;12(1):102.
    Species: Mouse
    Sample Types: Serum
  191. A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette-Gu�rin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-&alpha
    Authors: K Tajiri, K Imanaka-Yo, Y Tsujimura, K Matsuo, M Hiroe, K Aonuma, M Ieda, Y Yasutomi
    International Journal of Molecular Sciences, 2021-01-14;22(2):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  192. Complement-5 inhibition deters progression of fulminant hepatitis to acute liver failure in murine models
    Authors: J Kusakabe, K Hata, H Miyauchi, T Tajima, Y Wang, I Tamaki, J Kawasoe, Y Okamura, X Zhao, T Okamoto, T Tsuruyama, S Uemoto
    Cellular and Molecular Gastroenterology and Hepatology, 2021-01-12;0(0):.
    Species: Mouse
    Sample Types: Serum
  193. Fisetin protects against high fat diet-induced nephropathy by inhibiting inflammation and oxidative stress via the blockage of iRhom2/NF-&kappaB signaling
    Authors: G Chenxu, D Xianling, K Qin, H Linfeng, S Yan, X Mingxin, T Jun, X Minxuan
    International immunopharmacology, 2021-01-08;92(0):107353.
    Species: Mouse
    Sample Types: Serum
  194. Psoralidin, a major component of Psoraleae Fructus, induces inflammasome activation and idiosyncratic liver injury
    Authors: Y Wang, G Xu, Z Wang, R Li, X Zhan, H Liu, Q Qin, W Li, X Wang, M Zhang, J Tang, Z Bai, X Xiao
    International immunopharmacology, 2021-01-07;92(0):107352.
    Species: Mouse
    Sample Types: Serum
  195. CX3CR1 is a prerequisite for the development of cardiac hypertrophy and left ventricular dysfunction in mice upon transverse aortic constriction
    Authors: CK Weisheit, JL Kleiner, MB Rodrigo, ST Niepmann, S Zimmer, GD Duerr, M Coburn, C Kurts, S Frede, L Eichhorn
    PLoS ONE, 2021-01-07;16(1):e0243788.
    Species: Mouse
    Sample Types: Tissue Homogenates
  196. KLF4 down-regulation resulting from TLR4 promotion of ERK1/2 phosphorylation underpins inflammatory response in sepsis
    Authors: C Li, L Yu, C Mai, T Mu, Y Zeng
    Journal of Cellular and Molecular Medicine, 2020-12-27;0(0):.
    Species: Mouse
    Sample Types: Serum
  197. The Role of Soluble Uric Acid in Modulating Autophagy Flux and Inflammasome Activation during Bacterial Infection in Macrophages
    Authors: D Al-Awad, N Al-Emadi, M Abu-Madi, AA Al-Thani, SM Zughaier
    Biomedicines, 2020-12-12;8(12):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  198. Astrocyte-derived exosomes carry microRNA-17-5p to protect neonatal rats from hypoxic-ischemic brain damage via inhibiting BNIP-2 expression
    Authors: L Du, Y Jiang, Y Sun
    Neurotoxicology, 2020-12-10;83(0):28-39.
    Species: Mouse
    Sample Types: Tissue Homogenates
  199. Extracellular microvesicles that originated adipose tissue derived mesenchymal stem cells have the potential ability to improve rheumatoid arthritis on mice
    Authors: K Tsujimaru, M Takanashi, K Sudo, A Ishikawa, S Mineo, S Ueda, K Kumagai, M Kuroda
    Regenerative Therapy, 2020-12-09;15(0):305-311.
    Species: Mouse
    Sample Types: Serum
  200. Infusion of blood from mice displaying cerebral amyloidosis accelerates amyloid pathology in animal models of Alzheimer's disease
    Authors: R Morales, C Duran-Anio, J Bravo-Aleg, LD Estrada, M Shahnawaz, PP Hu, C Kramm, D Morales-Sc, A Urayama, C Soto
    Acta neuropathologica communications, 2020-12-07;8(1):213.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  201. Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1&alpha-NF-&kappaB Crosstalk In Vitro and In Vivo
    Authors: SN Chang, DK Dey, ST Oh, WH Kong, KH Cho, EM Al-Olayan, BS Hwang, SC Kang, JG Park
    International Journal of Molecular Sciences, 2020-12-04;21(23):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  202. An allosteric interleukin-1 receptor modulator mitigates inflammation and photoreceptor toxicity in a model of retinal degeneration
    Authors: R Dabouz, CWH Cheng, P Abram, S Omri, G Cagnone, KV Sawmy, JS Joyal, M Desjarlais, D Olson, AG Weil, W Lubell, JC Rivera, S Chemtob
    J Neuroinflammation, 2020-11-27;17(1):359.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  203. Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling
    Authors: Q Xu, Y Fan, JJ Loor, Y Liang, X Sun, H Jia, C Zhao, C Xu
    Frontiers in Pharmacology, 2020-11-13;11(0):601716.
    Species: Mouse
    Sample Types: Serum
  204. Dexmedetomidine attenuates sevoflurane?induced neurocognitive impairment through &alpha;2?adrenoceptors
    Authors: Y Zhang, M Li, E Cui, H Zhang, X Zhu, J Zhou, M Yan, J Sun
    Mol Med Rep, 2020-11-12;23(1):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  205. Alleviation of Ulcerative Colitis Potentially through th1/th2 Cytokine Balance by a Mixture of Rg3-enriched Korean Red Ginseng Extract and Persicaria tinctoria
    Authors: E Saba, YY Lee, MH Rhee, SD Kim
    Molecules, 2020-11-10;25(22):.
    Species: Mouse
    Sample Types: Plasma
  206. Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15
    Authors: Z Zhang, Y Wang, Y Shan, R Zhou, W Yin
    Sci Rep, 2020-11-06;10(1):19272.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  207. Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons
    Authors: DF Silva, E Candeias, AR Esteves, JD Magalhães, IL Ferreira, D Nunes-Cost, AC Rego, N Empadinhas, SM Cardoso
    J Neuroinflammation, 2020-11-05;17(1):332.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  208. TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity
    Authors: JJ Fuster, MA Zuriaga, V Zorita, S MacLauchla, MN Polackal, V Viana-Huet, A Ferrer-Pér, N Matesanz, A Herrero-Ce, S Sano, MA Cooper, H González-N, K Walsh
    Cell Rep, 2020-10-27;33(4):108326.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  209. CSF1R signaling is a regulator of pathogenesis in progressive MS
    Authors: N Hagan, JL Kane, D Grover, L Woodworth, C Madore, J Saleh, J Sancho, J Liu, Y Li, J Proto, M Zelic, A Mahan, M Kothe, AA Scholte, M Fitzgerald, B Gisevius, A Haghikia, O Butovsky, D Ofengeim
    Cell Death Dis, 2020-10-23;11(10):904.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  210. LPS-Induced Acute Kidney Injury Is Mediated by Nox4-SH3YL1
    Authors: JY Yoo, DR Cha, B Kim, EJ An, SR Lee, JJ Cha, YS Kang, JY Ghee, JY Han, YS Bae
    Cell Rep, 2020-10-20;33(3):108245.
    Species: Mouse
    Sample Types: Serum
  211. Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling
    Authors: B Zhou, J Liu, L Zeng, S Zhu, H Wang, TR Billiar, G Kroemer, DJ Klionsky, HJ Zeh, J Jiang, D Tang, R Kang
    Nat Microbiol, 2020-10-19;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
  212. Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-&beta1 up-regulate miR-132 and promote mouse M2 macrophage polarization
    Authors: Y Wang, B Han, Y Wang, C Wang, H Zhang, J Xue, X Wang, T Niu, Z Niu, Y Chen
    J. Cell. Mol. Med., 2020-09-23;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  213. Resveratrol alleviates intestinal mucosal barrier dysfunction in dextran sulfate sodium-induced colitis mice by enhancing autophagy
    Authors: HH Pan, XX Zhou, YY Ma, WS Pan, F Zhao, MS Yu, JQ Liu
    World J. Gastroenterol., 2020-09-07;26(33):4945-4959.
    Species: Mouse
    Sample Types: Plasma
  214. Alcohol consumption promotes colorectal cancer by altering intestinal permeability
    Authors: XY Diao, T Peng, FG Kong, JG Huang, S Han, YS Shang, H Liu
    Eur Rev Med Pharmacol Sci, 2020-09-01;24(18):9370-9377.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  215. Positive Effects of Preventive Nutrition Supplement on Anticancer Radiotherapy in Lung Cancer Bearing Mice
    Authors: YM Liu, TH Wu, YH Chiu, H Wang, TL Li, S Hsia, YL Chan, CJ Wu
    Cancers (Basel), 2020-08-28;12(9):.
    Species: Mouse
    Sample Types: Serum
  216. The alpha2 Na+/K+-ATPase isoform mediates LPS-induced neuroinflammation
    Authors: JA Leite, TJ Isaksen, A Heuck, C Scavone, K Lykke-Hart
    Sci Rep, 2020-08-25;10(1):14180.
    Species: Mouse
    Sample Types: Serum
  217. Myeloid FBW7 deficiency disrupts redox homeostasis and aggravates dietary-induced insulin resistance
    Authors: C Wang, Y Chao, W Xu, Z Liu, H Wang, K Huang
    Redox Biol, 2020-08-15;37(0):101688.
    Species: Mouse, Transgenic Mouse
    Sample Types: Plasma
  218. Preconditioning mesenchymal stromal cells with flagellin enhances the anti?inflammatory ability of their secretome against lipopolysaccharide?induced acute lung injury
    Authors: R Li, Y Li, X Dong
    Molecular Medicine Reports, 2020-07-28;0(0):.
    Species: Human, Mouse
    Sample Types: BALF
  219. Roseburia�intestinalis?derived flagellin ameliorates colitis by targeting miR?223?3p?mediated activation of NLRP3 inflammasome and pyroptosis
    Authors: X Wu, S Pan, W Luo, Z Shen, X Meng, M Xiao, B Tan, K Nie, T Tong, X Wang
    Mol Med Rep, 2020-07-23;0(0):.
    Species: Mouse
    Sample Types: Serum
  220. Nrf2 mitigates prolonged PM2.5 exposure-triggered liver inflammation by positively regulating SIKE activity: Protection by Juglanin
    Authors: C Ge, J Tan, S Zhong, L Lai, G Chen, J Zhao, C Yi, L Wang, L Zhou, T Tang, Q Yang, D Lou, Q Li, Y Wu, L Hu, G Kuang, X Liu, B Wang, M Xu
    Redox Biol, 2020-07-17;36(0):101645.
    Species: Mouse, Transgenic Mouse
    Sample Types: Serum, Tissue Homogenates
  221. Protective effects of catalpol on mitochondria of hepatocytes in cholestatic liver injury
    Authors: X Gao, J Xu, H Liu
    Mol Med Rep, 2020-07-13;22(3):2424-2432.
    Species: Mouse
    Sample Types: Serum
  222. Fisetin alleviates sepsis-induced multiple organ dysfunction in mice via inhibiting p38 MAPK/MK2 signaling
    Authors: HF Zhang, HB Zhang, XP Wu, YL Guo, WD Cheng, F Qian
    Acta Pharmacol. Sin., 2020-07-13;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  223. Combined administration of SHP2 inhibitor SHP099 and the &alpha7nAChR agonist PNU282987 protect mice against DSS?induced colitis
    Authors: J Xiao, G Zhang, S Gao, J Shen, H Feng, Z He, C Xu
    Mol Med Rep, 2020-07-10;22(3):2235-2244.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  224. Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis
    Authors: WC Chen, NJ Chen, HP Chen, WK Yu, VY Su, H Chen, HH Wu, KY Yang
    Int J Mol Sci, 2020-07-02;21(13):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  225. IL-1beta suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury
    Authors: S Xiong, Z Hong, LS Huang, Y Tsukasaki, S Nepal, A Di, M Zhong, W Wu, Z Ye, X Gao, GN Rao, D Mehta, J Rehman, AB Malik
    J. Clin. Invest., 2020-07-01;130(7):3684-3698.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  226. Apamin Suppresses LPS-Induced Neuroinflammatory Responses by Regulating SK Channels and TLR4-Mediated Signaling Pathways
    Authors: J Park, KM Jang, KK Park
    Int J Mol Sci, 2020-06-17;21(12):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  227. A Novel Peptide Oligomer of Bacitracin Induces M1 Macrophage Polarization by Facilitating Ca2+ Influx
    Authors: SY Ji, H Lee, H Hwangbo, SH Hong, HJ Cha, C Park, DH Kim, GY Kim, S Kim, HS Kim, JC Yoo, YH Choi
    Nutrients, 2020-05-29;12(6):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  228. The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by &beta-Glucan
    Authors: ST Keating, L Groh, CDCC van der He, H Rodriguez, JC Dos Santos, S Fanucchi, J Okabe, H Kaipananic, JH van Puffel, L Helder, MP Noz, V Matzaraki, Y Li, LCJ de Bree, VACM Koeken, SJCFM Moorlag, VP Mourits, J Domínguez-, M Oosting, EP Bulthuis, WJH Koopman, M Mhlanga, A El-Osta, LAB Joosten, MG Netea, NP Riksen
    Cell Rep, 2020-04-21;31(3):107548.
    Species: Mouse
    Sample Types: Plasma
  229. Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases
    Authors: W Shi, G Xu, X Zhan, Y Gao, Z Wang, S Fu, N Qin, X Hou, Y Ai, C Wang, T He, H Liu, Y Chen, Y Liu, J Wang, M Niu, Y Guo, X Xiao, Z Bai
    Cell Death Dis, 2020-04-20;11(4):252.
    Species: Mouse
    Sample Types: Serum
  230. Maternal high-fat diet exaggerates diet-induced insulin resistance in adult offspring by enhancing inflammasome activation through noncanonical pathway of caspase-11
    Authors: N Wada, H Yamada, S Motoyama, M Saburi, T Sugimoto, H Kubota, D Miyawaki, N Wakana, D Kami, T Ogata, S Matoba
    Mol Metab, 2020-04-06;37(0):100988.
    Species: Mouse
    Sample Types: Serum
  231. Monascin ameliorate inflammation in the lipopolysaccharide-induced BV-2 microglial cells via suppressing the NF-kappaB/p65 pathway
    Authors: YX Shi, WS Chen
    Iran J Basic Med Sci, 2020-04-01;23(4):461-468.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  232. Octominin Inhibits LPS-Induced Chemokine and Pro-inflammatory Cytokine Secretion from RAW 264.7 Macrophages via Blocking TLRs/NF-kappaB Signal Transduction
    Authors: KKA Sanjeewa, DP Nagahawatt, HW Yang, JY Oh, TU Jayawarden, YJ Jeon, M De Zoysa, I Whang, B Ryu
    Biomolecules, 2020-03-27;10(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  233. Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci
    Authors: A Famà, A Midiri, G Mancuso, C Biondo, G Lentini, R Galbo, MM Giardina, GV De Gaetano, L Romeo, G Teti, C Beninati
    MBio, 2020-03-24;11(2):.
    Species: Mouse
    Sample Types: Tissue Lysates
  234. Activation of ASC Inflammasome Driven by TLR4 Contributes to Host Immunity against Rickettsial Infection
    Authors: C Rumfield, I Hyseni, JW McBride, DH Walker, R Fang
    Infect. Immun., 2020-03-23;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  235. Attenuation of noisy environment-induced neuroinflammation and dysfunction of learning and memory by minocycline during perioperative period in mice
    Authors: F Lin, Y Zheng, L Pan, Z Zuo
    Brain Res. Bull., 2020-03-21;159(0):16-24.
    Species: Mouse
    Sample Types: Tissue Homogenates
  236. Nrf2 deficiency aggravates PM2.5-induced cardiomyopathy by enhancing oxidative stress, fibrosis and inflammation via RIPK3-regulated mitochondrial disorder
    Authors: C Ge, L Hu, D Lou, Q Li, J Feng, Y Wu, J Tan, M Xu
    Aging (Albany NY), 2020-03-17;12(6):4836-4865.
    Species: Mouse
    Sample Types: Serum
  237. Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury
    Authors: FQ Kong, SJ Zhao, P Sun, H Liu, J Jie, T Xu, AD Xu, YQ Yang, Y Zhu, J Chen, Z Zhou, DF Qian, CJ Gu, Q Chen, GY Yin, HW Zhang, J Fan
    J Neuroinflammation, 2020-02-17;17(1):62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  238. Effect of HBx on inflammation and mitochondrial oxidative stress in mouse hepatocytes
    Authors: LR Ling, DH Zheng, ZY Zhang, WH Xie, YH Huang, ZX Chen, XZ Wang, D Li
    Oncol Lett, 2020-02-17;19(4):2861-2869.
  239. Development of an IL-17A DNA Vaccine to Treat Systemic Lupus Erythematosus in Mice
    Authors: H Koriyama, Y Ikeda, H Nakagami, M Shimamura, S Yoshida, H Rakugi, R Morishita
    Vaccines (Basel), 2020-02-12;8(1):.
    Species: Mouse
    Sample Types: Serum
  240. Hydrogen Sulfide Attenuates Particulate Matter-Induced Emphysema and Airway Inflammation Through Nrf2-Dependent Manner
    Authors: G Jia, S Yu, W Sun, J Yang, Y Wang, Y Qi, Y Chen
    Front Pharmacol, 2020-02-07;11(0):29.
    Species: Mouse
    Sample Types: BALF
  241. Antagonizing binding of cell cycle and apoptosis regulatory protein 1 (CARP-1) to the NEMO/IKKgamma protein enhances the anticancer effect of chemotherapy
    Authors: J Venkatesh, SC Sekhar, VT Cheriyan, M Muthu, P Meister, E Levi, S Dzinic, JW Gauld, LA Polin, AK Rishi
    J. Biol. Chem., 2020-02-04;295(11):3532-3552.
    Species: Mouse
    Sample Types: Serum
  242. Ubiquitin fold modifier 1 activates NF-kappaB pathway by down-regulating LZAP expression in the macrophage of diabetic mouse model
    Authors: X Hu, H Zhang, Y Song, L Zhuang, Q Yang, M Pan, F Chen
    Biosci. Rep., 2020-01-31;40(1):.
    Species: Mouse
    Sample Types: Serum
  243. Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1&beta Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration
    Authors: Y Gao, D Tu, R Yang, CH Chu, JS Hong, HM Gao
    Int J Mol Sci, 2020-01-11;21(2):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  244. Tumor Cell-Derived IL1&beta Promotes Desmoplasia and Immune Suppression in Pancreatic Cancer
    Authors: S Das, B Shapiro, EA Vucic, S Vogt, D Bar-Sagi
    Cancer Res., 2020-01-08;80(5):1088-1101.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  245. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice
    Authors: C Quach, Y Song, H Guo, S Li, H Maazi, M Fung, N Sands, D O'Connell, S Restrepo-V, B Chai, D Nemecio, V Punj, O Akbari, GE Idos, SM Mumenthale, N Wu, SE Martin, A Hagiya, J Hicks, H Cui, C Liang
    Nat Commun, 2019-12-12;10(1):5681.
    Species: Mouse
    Sample Types: Serum
  246. Notoginsenoside R1 suppresses miR-301a via NF-kappaB pathway in lipopolysaccharide-treated ATDC5 cells
    Authors: Y Dong, X Yan, X Yang, C Yu, Y Deng, X Song, L Zhang
    Exp. Mol. Pathol., 2019-12-11;112(0):104355.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  247. Increased Soluble Epoxide Hydrolase in Human Gestational Tissues from Pregnancies Complicated by Acute Chorioamnionitis
    Authors: TH Hung, SF Chen, CH Wu, CC Kao, CP Wu
    Mediators Inflamm., 2019-12-05;2019(0):8687120.
    Species: Mouse
    Sample Types: Tissue Homogenates
  248. Oral flavonoid fisetin treatment protects against prolonged high-fat-diet-induced cardiac dysfunction by regulation of multicombined signaling
    Authors: LF Hu, J Feng, X Dai, Y Sun, M Xiong, L Lai, S Zhong, C Yi, G Chen, H Li, Q Yang, Q Kuang, T Long, J Zhan, T Tang, C Ge, J Tan, M Xu
    J. Nutr. Biochem., 2019-11-25;77(0):108253.
    Species: Mouse
    Sample Types: Serum
  249. Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice
    Authors: K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo
    Dis Model Mech, 2019-11-12;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  250. Benzydamine inhibits osteoclast differentiation and bone resorption via down-regulation of interleukin-1 &beta expression
    Authors: HS Son, J Lee, HI Lee, N Kim, YJ Jo, GR Lee, SE Hong, M Kwon, NY Kim, HJ Kim, JH Park, SY Lee, W Jeong
    Acta Pharm Sin B, 2019-11-08;10(3):462-474.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  251. Autophagy regulates the therapeutic potential of adipose-derived stem cells in LPS-induced pulmonary microvascular barrier damage
    Authors: C Li, J Pan, L Ye, H Xu, B Wang, H Xu, L Xu, T Hou, D Zhang
    Cell Death Dis, 2019-10-23;10(11):804.
    Species: Mouse
    Sample Types: BALF
  252. Downregulation of RalGTPase-activating protein promotes colitis-associated cancer via NLRP3 inflammasome activation
    Authors: T Iida, Daisuke Hi, N Minami, M Matsuura, K Wagatsuma, K Kawakami, K Nagaishi, M Nojima, H Ikeuchi, S Hirota, R Shirakawa, H Horiuchi, H Nakase
    Cell Mol Gastroenterol Hepatol, 2019-10-15;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  253. CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells
    Authors: P Wang, X Qi, G Xu, J Liu, J Guo, X Li, X Ma, H Sun
    Aging (Albany NY), 2019-09-26;11(18):7402-7415.
    Species: Mouse
    Sample Types: Tissue Homogenates
  254. NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis
    Authors: N Ershaid, Y Sharon, H Doron, Y Raz, O Shani, N Cohen, L Monteran, L Leider-Tre, A Ben-Shmuel, M Yassin, M Gerlic, A Ben-Baruch, M Pasmanik-C, R Apte, N Erez
    Nat Commun, 2019-09-26;10(1):4375.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  255. Gestational oxidative stress protects against adult obesity and insulin resistance
    Authors: LG Dimova, S Battista, T Plösch, RA Kampen, F Liu, RN Verkaik-Sc, D Pratico, HJ Verkade, UJF Tietge
    Redox Biol, 2019-09-17;28(0):101329.
    Species: Mouse
    Sample Types: Plasma
  256. Fucoxanthin, a Marine Xanthophyll Isolated From Conticribra weissflogii ND-8: Preventive Anti-Inflammatory Effect in a Mouse Model of Sepsis
    Authors: J Su, K Guo, M Huang, Y Liu, J Zhang, L Sun, D Li, KL Pang, G Wang, L Chen, Z Liu, Y Chen, Q Chen, L Huang
    Front Pharmacol, 2019-08-28;10(0):906.
    Species: Mouse
    Sample Types: Serum
  257. Macrophage migration inhibitory factor enhances influenza-associated mortality in mice
    Authors: CA Smith, DJ Tyrell, UA Kulkarni, S Wood, L Leng, RL Zemans, R Bucala, DR Goldstein
    JCI Insight, 2019-07-11;4(13):.
    Species: Mouse
    Sample Types: BALF
  258. Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment
    Authors: N Smith, MP Rodero, N Bekaddour, V Bondet, YB Ruiz-Blanc, M Harms, B Mayer, B Badder-Meu, P Quartier, C Bodemer, V Baudouin, Y Dieudonné, F Kirchhoff, E Sanchez Ga, B Charbit, N Leboulange, B Jahrsdörfe, Y Richard, AS Korganow, J Münch, S Nisole, D Duffy, JP Herbeuval
    Sci Adv, 2019-07-10;5(7):eaav9019.
    Species: Mouse
    Sample Types: Serum
  259. Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein
    Authors: PAM Cavalcante, N Alenina, A Budu, LC Freitas-Li, T Alves-Silv, JSH Agudelo, F Qadri, NOS Camara, M Bader, RC Araújo
    Mediators Inflamm., 2019-07-10;2019(0):9086758.
    Species: Mouse
    Sample Types: Tissue Lysates
  260. Immunomodulatory effect of mancozeb, chlorothalonil, and thiophanate methyl pesticides on macrophage cells
    Authors: GCC Weis, CE Assmann, FC Cadoná, BDSR Bonadiman, AO Alves, AK Machado, MMMF Duarte, IBM da Cruz, IH Costabeber
    Ecotoxicol. Environ. Saf., 2019-07-09;182(0):109420.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  261. Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury
    Authors: Z Ye, L Zhang, R Li, W Dong, S Liu, Z Li, H Liang, L Wang, W Shi, AB Malik, KT Cheng, X Liang
    Kidney Blood Press. Res., 2019-06-21;0(0):1-14.
    Species: Mouse
    Sample Types: Serum
  262. Carnosic acid alleviates brain injury through NF?κB?regulated inflammation and Caspase?3?associated apoptosis in high fat?induced mouse models
    Authors: Y Liu, Y Zhang, M Hu, YH Li, XH Cao
    Mol Med Rep, 2019-05-27;20(1):495-504.
    Species: Mouse
    Sample Types: Serum
  263. cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis
    Authors: R Chen, L Zeng, S Zhu, J Liu, HJ Zeh, G Kroemer, H Wang, TR Billiar, J Jiang, D Tang, R Kang
    Sci Adv, 2019-05-22;5(5):eaav5562.
    Species: Mouse
    Sample Types: Serum
  264. A Fragment of Apolipoprotein E4 Leads to the Downregulation of a CXorf56 Homologue, a Novel ER-Associated Protein, and Activation of BV2 Microglial Cells
    Authors: TB Pollock, JM Mack, RJ Day, NF Isho, RJ Brown, AE Oxford, BE Morrison, EJ Hayden, TT Rohn
    Oxid Med Cell Longev, 2019-05-06;2019(0):5123565.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  265. Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases
    Authors: HH Guo, CL Feng, WX Zhang, ZG Luo, HJ Zhang, TT Zhang, C Ma, Y Zhan, R Li, S Wu, Z Abliz, C Li, XL Li, XL Ma, LL Wang, WS Zheng, YX Han, JD Jiang
    Nat Commun, 2019-04-30;10(1):1981.
    Species: Mouse
    Sample Types: Plasma
  266. Avicularin Relieves Depressive-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice
    Authors: Z Shen, Y Xu, X Jiang, Z Wang, Y Guo, W Pan, J Hou
    Med. Sci. Monit., 2019-04-15;25(0):2777-2784.
    Species: Mouse
    Sample Types: Tissue Homogenates
  267. Circulating Cell-Free mtDNA Contributes to AIM2 Inflammasome-Mediated Chronic Inflammation in Patients with Type 2 Diabetes
    Authors: JH Bae, SI Jo, SJ Kim, JM Lee, JH Jeong, JS Kang, NJ Cho, SS Kim, EY Lee, JS Moon
    Cells, 2019-04-08;8(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  268. Induced Pluripotent Stem Cells Regulate TREM-1 Expression and the p38 MAPK Pathway in Endotoxin-Induced Acute Lung Injury
    Authors: VY Su, KY Yang, SH Chiou, NJ Chen, MH Mo, CS Lin, CT Wang
    Stem Cells, 2019-02-16;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  269. Melatonin Inhibits Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Cultured Mouse Mammary Tissue
    Authors: GM Yu, W Tan
    Mediators Inflamm., 2019-02-12;2019(0):8597159.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  270. Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis
    Authors: YH Kwon, H Wang, E Denou, JE Ghia, L Rossi, ME Fontes, SP Bernier, MS Shajib, S Banskota, SM Collins, MG Surette, WI Khan
    Cell Mol Gastroenterol Hepatol, 2019-02-01;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  271. The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion
    Authors: Y Xia, N Liu, X Xie, G Bi, H Ba, L Li, J Zhang, X Deng, Y Yao, Z Tang, B Yin, J Wang, K Jiang, Z Li, Y Choi, F Gong, X Cheng, JJ O'Shea, JJ Chae, A Laurence, XP Yang
    Autophagy, 2019-01-29;0(0):1-16.
    Species: Mouse
    Sample Types: Serum
  272. Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation
    Authors: Y Pan, X Hui, RLC Hoo, D Ye, CYC Chan, T Feng, Y Wang, KSL Lam, A Xu
    J. Clin. Invest., 2019-01-22;129(2):834-849.
    Species: Mouse
    Sample Types: Serum
  273. The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome
    Authors: MC Trotta, R Maisto, F Guida, S Boccella, L Luongo, C Balta, G D'Amico, H Herman, A Hermenean, C Bucolo, M D'Amico
    PLoS ONE, 2019-01-18;14(1):e0211005.
    Species: Mouse
    Sample Types: Serum
  274. Costunolide alleviates HKSA-induced acute lung injury via inhibition of macrophage activation
    Authors: YT Chen, Y Du, B Zhao, LX Gan, KK Yu, L Sun, J Wang, F Qian
    Acta Pharmacol. Sin., 2019-01-15;0(0):.
    Species: Mouse
    Sample Types: BALF
  275. The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice
    Authors: M Okuda, Y Fujita, H Sugimoto
    Biol. Pharm. Bull., 2019-01-01;42(10):1694-1706.
    Species: Mouse
    Sample Types: Tissue Homogenates
  276. TRAF3-interacting JNK-activating modulator promotes inflammation by stimulating� translocation of Toll-like receptor 4 to lipid rafts
    Authors: Y Li, J Guan, W Wang, C Hou, L Zhou, J Ma, Y Cheng, S Jiao, Z Zhou
    J. Biol. Chem., 2018-12-20;0(0):.
    Species: Mouse
    Sample Types: Serum
  277. Pharmacological stimulation of NQO1 decreases NADPH levels and ameliorates acute pancreatitis in mice
    Authors: A Shen, HJ Kim, GS Oh, SB Lee, S Lee, A Pandit, D Khadka, S Sharma, SY Kim, SK Choe, SH Yang, EY Cho, H Shim, R Park, TH Kwak, HS So
    Cell Death Dis, 2018-12-18;10(1):5.
    Species: Mouse
    Sample Types: Serum
  278. SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain
    Authors: A Tyagi, CU Nguyen, T Chong, CR Michel, KS Fritz, N Reisdorph, L Knaub, JEB Reusch, S Pugazhenth
    Sci Rep, 2018-12-03;8(1):17547.
    Species: Mouse
    Sample Types: Plasma
  279. A Novel Peroxidase Mimics and Ameliorates Alzheimer's Disease-Related Pathology and Cognitive Decline in Mice
    Authors: J Xu, K Wang, Y Yuan, H Li, R Zhang, S Guan, L Wang
    Int J Mol Sci, 2018-10-24;19(11):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  280. Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice.
    Authors: Li Z, Luo T, Ning X, Xiong C, Wu A
    Neurosci Lett, 2018-09-28;687(0):189-195.
    Species: Mouse
    Sample Types: Tissue Homogenates
  281. ?-Synuclein disrupts the anti-inflammatory role of Drd2 via interfering ?-arrestin2-TAB1 interaction in astrocytes
    Authors: RH Du, Y Zhou, ML Xia, M Lu, JH Ding, G Hu
    J Neuroinflammation, 2018-09-10;15(1):258.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  282. Activation of Bone Marrow-Derived Cells Angiotensin (Ang) II Type 1 Receptor by Ang II Promotes Atherosclerotic Plaque Vulnerability
    Authors: M Pellegrin, K Bouzourène, JF Aubert, A Nahimana, MA Duchosal, L Mazzolai
    Int J Mol Sci, 2018-09-04;19(9):.
    Species: Mouse
    Sample Types: Plasma
  283. Complement activation contributes to perioperative neurocognitive disorders in mice
    Authors: C Xiong, J Liu, D Lin, J Zhang, N Terrando, A Wu
    J Neuroinflammation, 2018-09-04;15(1):254.
    Species: Mouse
    Sample Types: Tissue Homogenates
  284. Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury
    Authors: Z Gong, J Pan, Q Shen, M Li, Y Peng
    J Neuroinflammation, 2018-08-28;15(1):242.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  285. Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury
    Authors: D Li, W Ren, Z Jiang, L Zhu
    Mol Med Rep, 2018-08-24;0(0):.
    Species: Mouse
    Sample Types: BALF
  286. Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice
    Authors: P Liang, W Shan, Z Zuo
    J Neuroinflammation, 2018-08-22;15(1):235.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  287. JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress
    Authors: X Zhu, MT Nedelcovyc, AG Thomas, Y Hasegawa, A Moreno-Meg, W Coomer, V Vohra, A Saito, G Perez, Y Wu, J Alt, E Prchalova, L Tenora, P Majer, R Rais, C Rojas, BS Slusher, A Kamiya
    Neuropsychopharmacology, 2018-08-13;0(0):.
    Species: Mouse
    Sample Types: Serum
  288. Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny
    Authors: A Beaudry-Ri, M Nadeau-Val, É Prairie, N Maurice, É Heckel, M Nezhady, S Pundir, A Madaan, A Boudreault, X Hou, C Quiniou, EM Sierra, A Beaulac, G Lodygensky, SA Robertson, J Keelan, K Adams-Wald, DM Olson, JC Rivera, WD Lubell, JS Joyal, JF Bouchard, S Chemtob
    Sci Rep, 2018-08-08;8(1):11875.
    Species: Mouse
    Sample Types: Tissue Homogenates
  289. Protective Effects of Nintedanib against Polyhexamethylene Guanidine Phosphate-Induced Lung Fibrosis in Mice
    Authors: HY Kim, MS Kim, SH Kim, D Joen, K Lee
    Molecules, 2018-08-07;23(8):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  290. The anticancer peptide RT53 induces immunogenic cell death
    Authors: E Pasquereau, J Habault, G Kroemer, JL Poyet
    PLoS ONE, 2018-08-06;13(8):e0201220.
    Species: Mouse
    Sample Types: Serum
  291. GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain
    Authors: S Bang, YK Xie, ZJ Zhang, Z Wang, ZZ Xu, RR Ji
    J. Clin. Invest., 2018-07-16;128(8):3568-3582.
    Species: Mouse
    Sample Types: Tissue Homogenates
  292. Myeloid p38? signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis
    Authors: C Youssif, M Cubillos-R, M Comalada, E Llonch, C Perna, N Djouder, AR Nebreda
    EMBO Mol Med, 2018-07-01;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  293. Inhibition of MicroRNA-23b Attenuates Immunosuppression in Late Sepsis through NIK, TRAF1 and XIAP
    Authors: H Zhang, H Li, A Shaikh, Y Caudle, B Yao, D Yin
    J. Infect. Dis., 2018-06-20;0(0):.
    Species: Mouse
    Sample Types: Serum
  294. Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms
    Authors: DT Skelly, ÉW Griffin, CL Murray, S Harney, C O'Boyle, E Hennessy, MA Dansereau, A Nazmi, L Tortorelli, JN Rawlins, DM Bannerman, C Cunningham
    Mol. Psychiatry, 2018-06-06;24(10):1533-1548.
    Species: Mouse
    Sample Types: Plasma
  295. Protective effects of Erigeron breviscapus Hand.- Mazz. (EBHM) extract in retinal neurodegeneration models
    Authors: J Zhu, L Chen, Y Qi, J Feng, L Zhu, Y Bai, H Wu
    Mol. Vis., 2018-04-25;24(0):315-325.
    Species: Rat
    Sample Types: Cell Culture Supernates
  296. Interleukin-1 receptor antagonist-mediated neuroprotection by umbilical cord-derived mesenchymal stromal cells following transplantation into a rodent stroke model
    Authors: SH Oh, C Choi, JE Noh, N Lee, YW Jeong, I Jeon, JM Shin, JH Kim, HJ Kim, JM Lee, HS Kim, OJ Kim, J Song
    Exp. Mol. Med., 2018-04-13;50(4):22.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  297. Macrophage-derived IL-1?/NF-?B signaling mediates parenteral nutrition-associated cholestasis
    Authors: KC El Kasmi, PM Vue, AL Anderson, MW Devereaux, S Ghosh, N Balasubram, SA Fillon, C Dahrenmoel, A Allawzi, C Woods, S McKenna, CJ Wright, L Johnson, A D'Alessand, JA Reisz, E Nozik-Gray, FJ Suchy, RJ Sokol
    Nat Commun, 2018-04-11;9(1):1393.
    Species: Mouse
    Sample Types: Serum
  298. Effect of internal contamination with tritiated water on the neoplastic colonies in the lungs, innate anti-tumour reactions, cytokine profile, and haematopoietic system in radioresistant and radiosensitive mice
    Authors: EM Nowosielsk, A Cheda, R Zdanowski, S Lewicki, BR Scott, MK Janiak
    Radiat Environ Biophys, 2018-04-06;0(0):.
    Species: Mouse
    Sample Types: Serum
  299. Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS
    Authors: HM Song, X Li, YY Liu, WP Lu, ZH Cui, L Zhou, D Yao, HM Zhang
    Int. J. Mol. Med., 2018-03-27;0(0):.
    Species: Mouse
    Sample Types: Serum
  300. MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
    Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
    J. Immunol., 2018-03-21;0(0):.
    Species: Mouse
    Sample Types: BALF
  301. Accelerated inflammation and oxidative stress induced by LPS in acute lung injury: ?nhibition by ST1926
    Authors: Z Dong, Y Yuan
    Int. J. Mol. Med., 2018-03-19;0(0):.
    Species: Mouse
    Sample Types: Serum
  302. REDD-1 aggravates endotoxin-induced inflammation via atypical NF-?B activation
    Authors: DK Lee, JH Kim, J Kim, S Choi, M Park, W Park, S Kim, KS Lee, T Kim, J Jung, YK Choi, KS Ha, MH Won, TR Billiar, YG Kwon, YM Kim
    FASEB J., 2018-03-16;0(0):fj201701436R.
    Species: Mouse
    Sample Types: Serum
  303. Crude extract and fractions from Eugenia uniflora Linn leaves showed anti-inflammatory, antioxidant, and antibacterial activities
    Authors: TR Falcão, AA de Araújo, LAL Soares, RT de Moraes, ICF Bezerra, MRA Ferreira, MA de Souza N, MCN Melo, RF de Araújo, ACV de Aguiar, JS de Medeiro, GCB Guerra
    BMC Complement Altern Med, 2018-03-09;18(1):84.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  304. Juglanin suppresses fibrosis and inflammation response caused by LPS in acute lung injury
    Authors: ZW Dong, YF Yuan
    Int. J. Mol. Med., 2018-03-09;41(6):3353-3365.
    Species: Mouse
    Sample Types: Serum
  305. Oleanolic acid acetate attenuates polyhexamethylene guanidine phosphate-induced pulmonary inflammation and fibrosis in mice
    Authors: MS Kim, JY Han, SH Kim, D Jeon, HY Kim, SW Lee, MC Rho, K Lee
    Respir Physiol Neurobiol, 2018-03-02;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  306. CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation
    Authors: S Piao, JW Lee, H Nagar, SB Jung, S Choi, S Kim, I Lee, SM Kim, N Shin, YR Lee, SD Lee, JB Park, K Irani, M Won, GM Hur, BH Jeon, DW Kim, CS Kim
    PLoS ONE, 2018-02-23;13(2):e0192693.
    Species: Mouse
    Sample Types: Plasma
  307. An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
    Authors: RG Carroll, Z Zas?ona, S Galván-Peñ, EL Koppe, DC Sévin, S Angiari, M Triantafil, K Triantafil, LK Modis, LA O'Neill
    J. Biol. Chem., 2018-02-20;293(15):5509-5521.
    Species: Mouse
    Sample Types: Serum
  308. SARM1 deletion restrains NAFLD induced by high fat diet (HFD) through reducing inflammation, oxidative stress and lipid accumulation
    Authors: ZG Pan, XS An
    Biochem. Biophys. Res. Commun., 2018-02-15;0(0):.
    Species: Mouse
    Sample Types: Serum
    Applications: ELISA Capture
  309. Immunization with Pseudomonas aeruginosa outer membrane vesicles stimulates protective immunity in mice
    Authors: X Zhang, F Yang, J Zou, W Wu, H Jing, Q Gou, H Li, J Gu, Q Zou, J Zhang
    Vaccine, 2018-02-14;36(8):1047-1054.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Capture
  310. An insight into the role of magnesium in the immunomodulatory properties of mesenchymal stem cells
    Authors: F da Silva L, AB da Rocha R, A Hastreiter, A Nogueira-P, E Makiyama, C Colli, RA Fock
    J. Nutr. Biochem., 2018-02-13;55(0):200-208.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  311. The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
    Authors: SS Chaurasia, RR Lim, BH Parikh, YS Wey, BB Tun, TY Wong, CD Luu, R Agrawal, A Ghosh, A Mortellaro, E Rackoczy, RR Mohan, VA Barathi
    Sci Rep, 2018-02-12;8(1):2847.
    Species: Mouse
    Sample Types: Tissue Homogenates
  312. Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice
    Authors: KS Chung, SY Cheon, SS Roh, M Lee, HJ An
    Nutrients, 2018-02-12;10(2):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
    Applications: ELISA Capture
  313. LncRNA GAS5 Overexpression Reverses LPS-Induced Inflammatory Injury and Apoptosis Through Up-Regulating KLF2 Expression in ATDC5 Chondrocytes
    Authors: F Li, J Sun, S Huang, G Su, G Pi
    Cell. Physiol. Biochem., 2018-02-09;45(3):1241-1251.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  314. Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice
    Authors: P Doddapatta, M Jain, N Dhanesha, SR Lentz, AK Chauhan
    Arterioscler. Thromb. Vasc. Biol., 2018-01-11;0(0):.
    Species: Mouse
    Sample Types: Plasma
  315. Oleocanthal-rich extra-virgin olive oil enhances donepezil effect by reducing amyloid-? load and related toxicity in a mouse model of Alzheimer's disease
    Authors: YS Batarseh, A Kaddoumi
    J. Nutr. Biochem., 2017-12-27;55(0):113-123.
    Species: Mouse
    Sample Types: Tissue Homogenates
  316. Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKK?/NF-?B signaling in mice
    Authors: JM Cho, SM Yun, YH Choi, J Heo, NJ Kim, SH Kim, EH Kim
    Oncotarget, 2017-12-12;9(1):866-880.
    Species: Mouse
    Sample Types: Serum
  317. Circulating soluble endoglin modifies the inflammatory response in mice
    Authors: L Ruiz-Remol, C Ollauri-Ib, L Pérez-Roqu, E Núñez-Góme, F Pérez-Barr, JM López-Novo, M Pericacho, A Rodríguez-
    PLoS ONE, 2017-11-16;12(11):e0188204.
    Species: Mouse
    Sample Types: Plasma
  318. Regulation of Arthritis Severity by the Acid Sphingomyelinase
    Authors: N Beckmann, KA Becker, S Walter, JU Becker, M Kramer, G Hessler, S Weber, JR Göthert, K Fassbender, E Gulbins, A Carpinteir
    Cell. Physiol. Biochem., 2017-10-16;43(4):1.
    Species: Mouse
    Sample Types: Tissue Homogenates
  319. Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling
    Authors: W Lu, D Jia, S An, M Mu, X Qiao, Y Liu, X Li, D Wang
    Sci Rep, 2017-08-21;7(1):8402.
    Species: Mouse
    Sample Types: Plasma
  320. Specific calpain inhibition protects kidney against inflammaging
    Authors: G Hanouna, L Mesnard, S Vandermeer, J Perez, S Placier, JP Haymann, F Campagne, J Moroch, A Bataille, L Baud, E Letavernie
    Sci Rep, 2017-08-14;7(1):8016.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  321. P2X7 receptor antagonism prevents IL-1? release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy
    Authors: MG Khalafalla, LT Woods, JM Camden, AA Khan, KH Limesand, MJ Petris, L Erb, GA Weisman
    J. Biol. Chem., 2017-08-10;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  322. Mitochondrial DNA-enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity
    Authors: Y Cai, MJ Xu, EH Koritzinsk, Z Zhou, W Wang, H Cao, PS Yuen, RA Ross, RA Star, S Liangpunsa, B Gao
    JCI Insight, 2017-07-20;2(14):.
    Species: Mouse
    Sample Types: Serum
  323. Interleukin-1 receptor in seizure susceptibility after traumatic injury to the pediatric brain
    Authors: BD Semple, TJ O'Brien, K Gimlin, DK Wright, S Eun Kim, PM Casillas-E, KM Webster, S Petrou, LJ Noble-Haeu
    J. Neurosci., 2017-07-19;0(0):.
    Species: Mouse
    Sample Types: Serum
  324. Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy
    Authors: EE To, R Vlahos, R Luong, ML Halls, PC Reading, PT King, C Chan, GR Drummond, CG Sobey, BRS Broughton, MR Starkey, R van der Sl, SR Lewin, S Bozinovski, LAJ O'Neill, T Quach, CJH Porter, DA Brooks, JJ O'Leary, S Selemidis
    Nat Commun, 2017-07-12;8(1):69.
    Species: Mouse
    Sample Types: BALF
  325. Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models
    Authors: F Yang, J Gu, L Yang, C Gao, H Jing, Y Wang, H Zeng, Q Zou, F Lv, J Zhang
    Sci Rep, 2017-06-21;7(1):3957.
    Species: Mouse
    Sample Types: BALF
  326. Chronic intermittent hypoxia induces liver fibrosis in mice with diet-induced obesity via TLR4/MyD88/MAPK/NF-kB signaling pathways
    Authors: HH Kang, IK Kim, HI Lee, H Joo, JU Lim, J Lee, SH Lee, HS Moon
    Biochem. Biophys. Res. Commun., 2017-06-13;0(0):.
    Species: Mouse
    Sample Types: Serum
  327. NAD(+) augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling
    Authors: A Shen, HJ Kim, GS Oh, SB Lee, SH Lee, A Pandit, D Khadka, SK Choe, SC Kwak, SH Yang, EY Cho, HS Kim, H Kim, R Park, TH Kwak, HS So
    Sci Rep, 2017-06-07;7(1):3006.
    Species: Mouse
    Sample Types: Serum
  328. STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection
    Authors: MT Stier, K Goleniewsk, JY Cephus, DC Newcomb, TP Sherrill, KL Boyd, MH Bloodworth, ML Moore, K Chen, JK Kolls, RS Peebles
    J. Immunol., 2017-06-02;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  329. Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis
    Authors: Y Guo, C Xie, X Li, J Yang, T Yu, R Zhang, T Zhang, D Saxena, M Snyder, Y Wu, X Li
    Nat Commun, 2017-05-31;8(0):15621.
    Species: Mouse
    Sample Types: Serum
  330. Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production
    Authors: H Ahn, E Jeon, JC Kim, SG Kang, SI Yoon, HJ Ko, PH Kim, GS Lee
    Sci Rep, 2017-05-02;7(1):1314.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  331. Xenotransplantation of layer-by-layer encapsulated non-human primate islets with a specified immunosuppressive drug protocol
    Authors: MR Haque, J Kim, H Park, HS Lee, KW Lee, TA Al-Hilal, JH Jeong, CH Ahn, DS Lee, SJ Kim, Y Byun
    J Control Release, 2017-04-19;0(0):.
    Species: Mouse
    Sample Types: Serum
  332. Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology
    Authors: SJ Whitfield, C Taylor, JE Risdall, GD Griffiths, JT Jones, ED Williamson, S Rijpkema, L Saraiva, S Vessillier, AC Green, AJ Carter
    J. Immunol, 2017-03-20;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  333. Acute fasting inhibits central caspase-1 activity reducing anxiety-like behavior and increasing novel object and object location recognition
    Authors: AE Towers, ML Oelschlage, J Patel, SJ Gainey, RH McCusker, GG Freund
    Metab. Clin. Exp., 2017-03-09;71(0):70-82.
    Species: Mouse
    Sample Types: Tissue Homogenates
  334. Cthrc1 lowers pulmonary collagen associated with bleomycin-induced fibrosis and protects lung function
    Authors: AP Binks, M Beyer, R Miller, RJ LeClair
    Physiol Rep, 2017-03-01;5(5):.
    Species: Mouse
    Sample Types: BALF
  335. Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa
    Authors: S Hopp, MW Nolte, C Stetter, C Kleinschni, AL Sirén, C Albert-Wei
    J Neuroinflammation, 2017-02-20;14(1):39.
    Species: Mouse
    Sample Types: Plasma
  336. Effects of polysaccharide fractions isolated from Caltha palustris L. on the activity of phagocytic cells & humoral immune response in mice with collagen-induced arthritis: A comparison with methotrexate
    Authors: A Suszko, B Obmi?ska-M
    Indian J. Med. Res., 2017-02-01;145(2):229-236.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  337. Adverse Effect Profile of Topical Ocular Administration of Fingolimod for Treatment of Dry Eye Disease
    Authors: Weibao Xiao
    Basic Clin. Pharmacol. Toxicol, 2017-01-22;0(0):.
    Species: Mouse
    Sample Types: Tears
  338. C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia
    PLoS Pathog, 2016-12-06;12(12):e1006038.
    Species: Mouse
    Sample Types: Tissue Homogenates
  339. Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-? Stimulated Gene/Protein 6
    Sci Rep, 2016-12-05;6(0):38438.
    Species: Mouse
    Sample Types: Serum
  340. Effects of the stem extracts of Schisandra glaucescens Diels on collagen-induced arthritis in Balb/c mice
    Authors: Jinbo Fang
    J Ethnopharmacol, 2016-11-10;0(0):.
    Species: Mouse
    Sample Types: Serum
  341. Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice
    Sci Rep, 2016-11-07;6(0):36696.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  342. EP4 Receptor-Associated Protein in Macrophages Protects against Bleomycin-Induced Pulmonary Inflammation in Mice
    Authors: Manabu Minami
    J. Immunol., 2016-10-31;0(0):.
    Species: Mouse
    Sample Types: BALF
  343. Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF
    Proc Natl Acad Sci USA, 2016-09-20;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  344. Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXR? signalling pathway in oxLDL-loaded macrophages
    J Cell Mol Med, 2016-09-15;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  345. KLHDC10 Deficiency Protects Mice against TNF?-Induced Systemic Inflammation
    PLoS ONE, 2016-09-15;11(9):e0163118.
    Species: Mouse
    Sample Types: Serum
  346. A Critical Role for P2X7 Receptor-Induced VCAM-1 Shedding and Neutrophil Infiltration during Acute Lung Injury
    J Immunol, 2016-08-24;0(0):.
    Species: Mouse
    Sample Types: BALF
  347. Kruppel-like factor 6 promotes macrophage-mediated inflammation by suppressing B cell leukemia/lymphoma 6 expression
    J Biol Chem, 2016-08-18;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  348. DNMT1-PPAR? pathway in macrophages regulates chronic inflammation and atherosclerosis development in mice
    Sci Rep, 2016-08-17;6(0):30053.
    Species: Mouse
    Sample Types: Plasma
  349. Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
    PLoS ONE, 2016-08-01;11(8):e0158735.
    Species: Mouse
    Sample Types: BALF
  350. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS
    Authors: Yong Hwan Park
    Nat Immunol, 2016-06-06;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  351. Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
    Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
    Cancer Discov, 2016-04-12;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  352. Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-kappaB and AP-1 Activation.
    Authors: Fan B, Dun S, Gu J, Guo Y, Ikuyama S
    PLoS ONE, 2015-09-14;10(9):e0137837.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  353. Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells.
    Authors: Jeschke A, Catala-Lehnen P, Sieber S, Bickert T, Schweizer M, Koehne T, Wintges K, Marshall R, Mautner A, Duchstein L, Otto B, Horst A, Amling M, Kreienkamp H, Schinke T
    J Immunol, 2015-09-11;195(8):3675-84.
    Species: Mouse
    Sample Types: Serum
  354. Novel Noncompetitive IL-1 Receptor-Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth.
    Authors: Nadeau-Vallee M, Quiniou C, Palacios J, Hou X, Erfani A, Madaan A, Sanchez M, Leimert K, Boudreault A, Duhamel F, Rivera J, Zhu T, Noueihed B, Robertson S, Ni X, Olson D, Lubell W, Girard S, Chemtob S
    J Immunol, 2015-08-24;195(7):3402-15.
    Species: Mouse
    Sample Types: Plasma
  355. RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality.
    Authors: Meng L, Jin W, Wang X
    Proc Natl Acad Sci U S A, 2015-08-17;112(35):11007-12.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  356. Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
    Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
    J Immunol, 2015-04-17;194(11):5407-16.
    Species: Mouse
    Sample Types: BALF
  357. Sevoflurane inhibits nuclear factor-kappaB activation in lipopolysaccharide-induced acute inflammatory lung injury via toll-like receptor 4 signaling.
    Authors: Sun X, Li X, Wang X, Tan W, Wang J
    PLoS ONE, 2015-04-14;10(4):e0122752.
    Species: Mouse
    Sample Types: BALF
  358. Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response.
    Authors: O'Callaghan P, Li J, Lannfelt L, Lindahl U, Zhang X
    J Biol Chem, 2015-04-13;290(24):14904-14.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  359. Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice.
    Authors: Chien C, Lee M, Liou H, Liou H, Fu W
    PLoS ONE, 2015-02-23;10(2):e0115827.
    Species: Mouse
    Sample Types: Tissue Homogenates
  360. Accelerated tumor progression in mice lacking the ATP receptor P2X7.
    Authors: Adinolfi E, Capece M, Franceschini A, Falzoni S, Giuliani A, Rotondo A, Sarti A, Bonora M, Syberg S, Corigliano D, Pinton P, Jorgensen N, Abelli L, Emionite L, Raffaghello L, Pistoia V, Di Virgilio F
    Cancer Res, 2014-12-26;75(4):635-44.
    Species: Mouse
    Sample Types: Plasma
  361. Chronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6.
    Authors: Qiu S, Feng Y, LeSage G, Zhang Y, Stuart C, He L, Li Y, Caudle Y, Peng Y, Yin D
    J Immunol, 2014-12-24;194(3):1021-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  362. Methylsulfonylmethane inhibits NLRP3 inflammasome activation.
    Authors: Ahn H, Kim J, Lee M, Kim Y, Cho Y, Lee G
    Cytokine, 2014-11-21;71(2):223-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  363. Macrophage control of phagocytosed mycobacteria is increased by factors secreted by alveolar epithelial cells through nitric oxide independent mechanisms.
    Authors: Petursdottir D, Chuquimia O, Freidl R, Fernandez C
    PLoS ONE, 2014-08-04;9(8):e103411.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  364. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
    Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
    Nat Commun, 2014-07-14;5(0):4436.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  365. The effects of protein malnutrition on the TNF-RI and NF-kappaB expression via the TNF-alpha signaling pathway.
    Authors: de Oliveira D, Hastreiter A, Mello A, de Oliveira Beltran J, Oliveira Santos E, Borelli P, Fock R
    Cytokine, 2014-07-06;69(2):218-25.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  366. Role of TLR5 and flagella in bacillus intraocular infection.
    Authors: Parkunan, Salai Ma, Astley, Roger, Callegan, Michelle
    PLoS ONE, 2014-06-24;9(6):e100543.
    Species: Mouse
    Sample Types: Tissue Homogenates
  367. Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1.
    Authors: Annamanedi M, Kalle A
    PLoS ONE, 2014-06-20;9(6):e99285.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  368. Neurodegeneration by activation of the microglial complement-phagosome pathway.
    Authors: Bodea L, Wang Y, Linnartz-Gerlach B, Kopatz J, Sinkkonen L, Musgrove R, Kaoma T, Muller A, Vallar L, Di Monte D, Balling R, Neumann H
    J Neurosci, 2014-06-18;34(25):8546-56.
    Species: Mouse
    Sample Types: Plasma
  369. Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.
    Authors: Xie H, Lu J, Rolhion N, Holden D, Nie P, Zhou Y, Yu X
    Infect Immun, 2014-06-02;82(8):3436-45.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  370. The inflammasome pyrin contributes to pertussis toxin-induced IL-1beta synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis.
    Authors: Dumas A, Amiable N, de Rivero Vaccari J, Chae J, Keane R, Lacroix S, Vallieres L
    PLoS Pathog, 2014-05-29;10(5):e1004150.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  371. Differences in PGE2 production between primary human monocytes and differentiated macrophages: role of IL-1beta and TRIF/IRF3.
    Authors: Endo Y, Blinova K, Romantseva T, Golding H, Zaitseva M
    PLoS ONE, 2014-05-28;9(5):e98517.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  372. Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.
    Authors: Yamane, Kazuhiko, Indalao, Irene L, Chida, Junji, Yamamoto, Yoshikaz, Hanawa, Masaaki, Kido, Hiroshi
    PLoS ONE, 2014-05-27;9(5):e98032.
    Species: Mouse
    Sample Types: Tissue Homogenates
  373. Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain.
    Authors: Dengler E, Alberti L, Bowman B, Kerwin A, Wilkerson J, Moezzi D, Limanovich E, Wallace J, Milligan E
    J Neuroinflammation, 2014-05-21;11(0):92.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  374. Running exercise alleviates trabecular bone loss and osteopenia in hemizygous beta-globin knockout thalassemic mice.
    Authors: Thongchote K, Svasti S, Teerapornpuntakit J, Krishnamra N, Charoenphandhu N
    Am J Physiol Endocrinol Metab, 2014-04-29;306(12):E1406-17.
    Species: Mouse
    Sample Types: Serum
  375. NF-kappaB signaling modulates radiationinduced microglial activation.
    Authors: Xue J, Dong J, Huang G, Qu X, Wu G, Dong X
    Oncol Rep, 2014-04-23;31(6):2555-60.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  376. CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
    Authors: Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A
    J Immunol, 2014-03-17;192(8):3816-27.
    Species: Mouse
    Sample Types: Tissue Homogenates
  377. Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
    Authors: Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X
    J Biol Chem, 2014-03-13;289(16):11522-35.
    Species: Mouse
    Sample Types: Whole Cells
  378. Pseudomonas aeruginosa MucD protease mediates keratitis by inhibiting neutrophil recruitment and promoting bacterial survival.
    Authors: Mochizuki Y, Suzuki T, Oka N, Zhang Y, Hayashi Y, Hayashi N, Gotoh N, Ohashi Y
    Invest Ophthalmol Vis Sci, 2014-01-09;55(1):240-6.
    Species: Mouse
    Sample Types: Tissue Homogenates
  379. Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.
    Authors: Snowden J, Beaver M, Beenken K, Smeltzer M, Horswill A, Kielian T
    PLoS ONE, 2013-12-30;8(12):e84089.
    Species: Mouse
    Sample Types: Tissue Homogenates
  380. CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.
    Authors: Bignon A, Gaudin F, Hemon P, Tharinger H, Mayol K, Walzer T, Loetscher P, Peuchmaur M, Berrebi D, Balabanian K
    J Immunol, 2013-12-23;192(3):886-96.
    Species: Mouse
    Sample Types: Serum
  381. Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.
    Authors: Vergadi, Eleni, Vaporidi, Katerina, Theodorakis, Emmanuel, Doxaki, Christin, Lagoudaki, Eleni, Ieronymaki, Elefther, Alexaki, Vassilia, Helms, Mike, Kondili, Eumorfia, Soennichsen, Birte, Stathopoulos, Efstathi, Margioris, Andrew N, Georgopoulos, Dimitrio, Tsatsanis, Christos
    J Immunol, 2013-11-25;192(1):394-406.
    Species: Mouse
    Sample Types: BALF
  382. Spironolactone attenuates bleomycin-induced pulmonary injury partially via modulating mononuclear phagocyte phenotype switching in circulating and alveolar compartments.
    Authors: Ji W, Ma Y, Zhou X, Zhang Y, Lu R, Guo Z, Sun H, Hu D, Yang G, Li Y, Wei L
    PLoS ONE, 2013-11-19;8(11):e81090.
    Species: Mouse
    Sample Types: BALF
  383. Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
    Authors: Lin J, Sun B, Jiang C, Hong H, Zheng Y
    Biochem Biophys Res Commun, 2013-11-06;441(4):897-903.
    Species: Mouse
    Sample Types: Serum
  384. Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5).
    Authors: Wintges K, Beil F, Albers J, Jeschke A, Schweizer M, Claass B, Tiegs G, Amling M, Schinke T
    J Bone Miner Res, 2013-10-01;28(10):2070-80.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  385. Sufficient production of geranylgeraniol is required to maintain endotoxin tolerance in macrophages.
    Authors: Kim J, Lee J, Ye J, Hao R, Debose-Boyd R, Ye J
    J Lipid Res, 2013-09-23;54(12):3430-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  386. CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model.
    Authors: Besnard A, Struyf S, Guabiraba R, Fauconnier L, Rouxel N, Proost P, Uyttenhove C, Van Snick J, Couillin I, Ryffel B
    J Leukoc Biol, 2013-08-23;94(6):1317-23.
    Species: Mouse
    Sample Types: Tissue Homogenates
  387. A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury.
    Authors: Campolo M, Esposito E, Ahmad A, Di Paola R, Wallace J, Cuzzocrea S
    FASEB J, 2013-07-30;27(11):4489-99.
    Species: Mouse
    Sample Types: Whole Tissue
  388. Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
    Authors: Kim, Janice J, Bridle, Byram W, Ghia, Jean-Eri, Wang, Huaqing, Syed, Shahzad, Manocha, Marcus M, Rengasamy, Palanive, Shajib, Mohammad, Wan, Yonghong, Hedlund, Peter B, Khan, Waliul I
    J Immunol, 2013-04-03;190(9):4795-804.
    Species: Mouse
    Sample Types: Tissue Homogenates
  389. Sustained interleukin-1beta overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.
    Authors: Ghosh S, Wu M, Shaftel S, Kyrkanides S, Laferla F, Olschowka J, O'Banion M
    J Neurosci, 2013-03-13;33(11):5053-64.
    Species: Mouse
    Sample Types: Tissue Homogenates
  390. Bcl-2 overexpression ameliorates immune complex-mediated arthritis by altering FcgammaRIIb expression and monocyte homeostasis.
    Authors: Lawlor K, van Nieuwenhuijze A, Parker K, Drake S, Campbell I, Smith S, Vince J, Strasser A, Wicks I
    J Leukoc Biol, 2013-01-22;93(4):585-97.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  391. mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
    Authors: Fan W, Cheng K, Qin X, Narsinh K, Wang S, Hu S, Wang Y, Chen Y, Wu J, Xiong L, Cao F
    Stem Cells, 2013-01-01;31(1):203-14.
    Species: Mouse
    Sample Types: Tissue Homogenates
  392. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
    Authors: Heneka M, Kummer M, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng T, Gelpi E, Halle A, Korte M, Latz E, Golenbock D
    Nature, 2012-12-19;493(7434):674-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  393. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
    Authors: Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, Boireau W, Simon B, Ryffel B, Connat J, Kanellopoulos J, Martin F, Rebe C, Apetoh L, Ghiringhelli F
    Nat Med, 2012-12-02;19(1):57-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  394. Netrin-1 protects against L-Arginine-induced acute pancreatitis in mice.
    Authors: Chen J, Cai Q, Shen P, Yan R, Wang C, Yang D, Fu H, Chen X
    PLoS ONE, 2012-09-27;7(9):e46201.
    Species: Mouse
    Sample Types: Plasma
  395. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1.
    Authors: Broz P, Ruby T, Belhocine K, Bouley D, Kayagaki N, Dixit V, Monack D
    Nature, 2012-08-15;490(7419):288-91.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  396. Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection.
    Authors: Huang H, Chen Y, Liang K, Jheng Y, Jhao J, Su M, Lee-Chen G, Hsieh-Li H
    PLoS ONE, 2012-07-23;7(7):e39656.
    Species: Mouse
    Sample Types: Plasma
  397. Treatment of diabetic mice with undenatured whey protein accelerates the wound healing process by enhancing the expression of MIP-1alpha, MIP-2, KC, CX3CL1 and TGF-beta in wounded tissue.
    BMC Immunol., 2012-06-18;13(0):32.
    Species: Mouse
    Sample Types: Tissue Homogenates
  398. Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
    Authors: Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ
    J. Biol. Chem., 2012-03-23;287(20):16356-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  399. Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-kappaB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury.
    J. Cell. Sci., 2012-03-16;91(6):921-32.
    Species: Mouse
    Sample Types: BALF
  400. The axonal guidance receptor neogenin promotes acute inflammation.
    Authors: Konig K, Gatidou D, Granja T, Meier J, Rosenberger P, Mirakaj V
    PLoS ONE, 2012-03-06;7(3):e32145.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  401. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
    Authors: Gottfries J, Melgar S, Michaelsson E
    PLoS ONE, 2012-01-18;7(1):e30005.
    Species: Mouse
    Sample Types: Tissue Homogenates
  402. Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.
    Authors: Deng T, Zhang Y, Chen Q, Yan K, Han D
    Immunology, 2012-01-01;135(1):40-50.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  403. Sphingosine regulates the NLRP3-inflammasome and IL-1beta release from macrophages.
    Authors: Luheshi NM, Giles JA, Lopez-Castejon G, Brough D
    Eur. J. Immunol., 2011-12-27;42(3):716-25.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  404. HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
    Authors: Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD
    PLoS Genet., 2011-10-20;7(10):e1002336.
    Species: Mouse
    Sample Types: Serum
  405. Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-alpha stimulated gene/protein 6.
    Authors: Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH, Prockop DJ
    Stem Cells, 2011-10-01;29(10):1572-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  406. WNT5A Signaling Contributes to Abeta-Induced Neuroinflammation and Neurotoxicity.
    Authors: Li B, Zhong L, Yang X, Andersson T, Huang M, Tang SJ
    PLoS ONE, 2011-08-17;6(8):e22920.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  407. Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis.
    Authors: Nakahama T, Kimura A, Nguyen NT, Chinen I, Hanieh H, Nohara K, Fujii-Kuriyama Y, Kishimoto T
    Proc. Natl. Acad. Sci. U.S.A., 2011-08-08;108(34):14222-7.
    Species: Mouse
    Sample Types: Serum
  408. Role of IL-1alpha and the Nlrp3/caspase-1/IL-1beta axis in cigarette smoke-induced pulmonary inflammation and COPD.
    Authors: Pauwels NS, Bracke KR, Dupont LL, Van Pottelberge GR, Provoost S, Vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Brusselle GG
    Eur. Respir. J., 2011-05-26;38(5):1019-28.
    Species: Mouse
    Sample Types: BALF
  409. IL-33-activated dendritic cells are critical for allergic airway inflammation.
    Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
    Eur. J. Immunol., 2011-05-25;41(6):1675-86.
    Species: Mouse
    Sample Types: BALF
  410. Crawling Phagocytes Recruited in the Brain Vasculature after Pertussis Toxin Exposure through IL6, ICAM1 and ITGalphaM.
    Authors: Richard JF, Roy M, Audoy-Remus J, Tremblay P, Vallieres L
    Brain Pathol., 2011-05-23;21(0):661.
    Species: Mouse
    Sample Types: Serum
  411. Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
    Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
    Am. J. Pathol., 2011-05-10;179(1):302-14.
    Species: Mouse
    Sample Types: Tissue Homogenates
  412. Fasting induces an anti-inflammatory effect on the neuroimmune system which a high-fat diet prevents.
    Authors: Lavin DN, Joesting JJ, Chiu GS, Moon ML, Meng J, Dilger RN, Freund GG
    Obesity (Silver Spring), 2011-04-28;19(8):1586-94.
    Species: Mouse
    Sample Types: Serum
  413. Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation.
    Authors: Mirakaj V, Brown S, Laucher S, Steinl C, Klein G, Kohler D, Skutella T, Meisel C, Brommer B, Rosenberger P, Schwab JM
    Proc. Natl. Acad. Sci. U.S.A., 2011-04-05;108(16):6555-60.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  414. Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10.
    Authors: Wang H, Cheng F
    J. Immunol., 2011-03-02;186(0):3986.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  415. Serotonin activates dendritic cell function in the context of gut inflammation.
    Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
    Am. J. Pathol., 2011-02-01;178(2):662-71.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  416. Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence.
    Authors: Kaplan IM, Morisot S, Heiser D, Cheng WC, Kim MJ, Civin CI
    J. Immunol., 2011-01-26;186(5):2826-34.
    Species: Mouse
    Sample Types: Plasma
  417. TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
    Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
    J. Immunol., 2010-11-22;186(1):556-62.
    Species: Mouse
    Sample Types: BALF
  418. Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.
    Authors: Brenneis C, Coste O, Altenrath K, Angioni C, Schmidt H, Schuh CD, Zhang DD, Henke M, Weigert A, Brune B, Rubin B, Nusing R, Scholich K, Geisslinger G
    J. Biol. Chem., 2010-11-12;286(3):2331-42.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  419. Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages.
    Authors: McCoy AJ, Koizumi Y, Toma C, Higa N, Dixit V, Taniguchi S, Tschopp J, Suzuki T
    Eur. J. Immunol., 2010-10-01;40(10):2797-803.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  420. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes.
    Authors: Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nunez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA
    Nat. Immunol., 2010-09-12;11(10):897-904.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  421. Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.
    Authors: Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Muller S, Follo M, Peters C, Reinheckel T
    Oncogene, 2010-09-06;30(1):54-64.
    Species: Mouse
    Sample Types: Tissue Homogenates
  422. TLR4 is a negative regulator in noninfectious lung inflammation.
    Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
    J. Immunol., 2010-03-31;184(9):5308-14.
    Species: Mouse
    Sample Types: BALF
  423. Loss of ability to self-heal malaria upon taurine transporter deletion.
    Authors: Delic D, Warskulat U, Borsch E, Al-Qahtani S, Al-Quraishi S, Haussinger D, Wunderlich F
    Infect. Immun., 2010-01-25;78(4):1642-9.
    Species: Mouse
    Sample Types: Serum
  424. Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta.
    Authors: Lewis SS, Hutchinson MR, Rezvani N, Loram LC, Zhang Y, Maier SF, Rice KC, Watkins LR
    Neuroscience, 2010-01-20;165(2):569-83.
    Species: Mouse
    Sample Types: Cell Lysates
  425. Galectin-3 contributes to neonatal hypoxic-ischemic brain injury.
    Authors: Doverhag C, Hedtjarn M, Poirier F, Mallard C, Hagberg H, Karlsson A, Savman K
    Neurobiol. Dis., 2010-01-04;38(1):36-46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  426. Absence or inhibition of matrix metalloproteinase-8 decreases ventilator-induced lung injury.
    Authors: Albaiceta GM, Gutierrez-Fernandez A, Garcia-Prieto E, Puente XS, Parra D, Astudillo A, Campestre C, Cabrera S, Gonzalez-Lopez A, Fueyo A, Taboada F, Lopez-Otin C
    Am. J. Respir. Cell Mol. Biol., 2009-12-07;43(5):555-63.
    Species: Mouse
    Sample Types: Tissue Homogenates
  427. Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
    Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
    J. Invest. Dermatol., 2009-11-19;130(3):866-75.
    Species: Mouse
    Sample Types: Tissue Homogenates
  428. Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept.
    Authors: Aden U, Favrais G, Plaisant F, Winerdal M, Felderhoff-Mueser U, Lampa J, Lelievre V, Gressens P
    Brain Behav. Immun., 2009-10-25;24(5):747-58.
    Species: Mouse
    Sample Types: Tissue Homogenates
  429. Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
    Authors: Sio SW, Moochhala S, Lu J
    Am. J. Respir. Crit. Care Med., 2009-10-01;181(1):36-46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  430. Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.
    Authors: Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009-09-25;298(1):L67-78.
    Species: Mouse
    Sample Types: BALF
  431. Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
    Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
    Am. J. Respir. Crit. Care Med., 2009-09-17;180(12):1208-17.
    Species: Mouse
    Sample Types: BALF
  432. Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice.
    Authors: Mizutani N, Nabe T, Yoshino S
    J. Immunol., 2009-08-14;183(6):4039-46.
    Species: Mouse
    Sample Types: BALF
  433. Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
    Authors: Hayashida K, Parks WC, Park PW
    Blood, 2009-07-28;114(14):3033-43.
    Species: Mouse
    Sample Types: Serum
  434. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
    Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
    J Biol Chem, 2009-07-15;284(36):24035-48.
    Species: Mouse
    Sample Types: Plasma
  435. Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice.
    Authors: Surguladze D, Deevi D, Claros N, Corcoran E, Wang S, Plym MJ, Wu Y, Doody J, Mauro DJ, Witte L, Busam KJ, Pytowski B, Rodeck U, Tonra JR
    Cancer Res., 2009-07-07;69(14):5643-7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  436. VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
    Authors: Pushparaj PN, Tay HK, Wang CC, Hong W, Melendez AJ
    J. Immunol., 2009-06-29;183(2):1413-8.
    Species: Mouse
    Sample Types: Serum
  437. A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
    Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
    J. Immunol., 2009-06-19;183(2):1291-300.
    Species: Mouse
    Sample Types: BALF
  438. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
    Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
    Nature, 2009-06-03;460(7252):269-73.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  439. Secretory lysosome targeting and induced secretion of human soluble TNF-alpha receptor in murine hematopoietic cells in vivo as a principle for immunoregulation in inflammation and malignancy.
    Authors: Johansson AC, Nandakumar KS, Persson AM, Olsson I, Hansson M
    Exp. Hematol., 2009-05-30;37(8):969-78.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  440. C/EBPalpha is required for pulmonary cytoprotection during hyperoxia.
    Authors: Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009-05-22;297(2):L286-98.
    Species: Mouse
    Sample Types: Tissue Homogenates
  441. Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis.
    Authors: Reed JR, Leon RP, Hall MK, Schwertfeger KL
    Breast Cancer Res., 2009-04-24;11(2):R21.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  442. Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro.
    Authors: Wang C, Duan H, He L
    Eur. J. Pharmacol., 2009-04-06;612(1):143-52.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  443. Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
    Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
    Int. Immunol., 2009-03-18;21(5):555-65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  444. Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells.
    Authors: Tao JY, Zheng GH, Zhao L, Wu JG, Zhang XY, Zhang SL, Huang ZJ, Xiong FL, Li CM
    J Ethnopharmacol, 2009-03-03;123(1):97-105.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  445. Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages.
    Authors: Cheon MS, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK
    J Ethnopharmacol, 2009-02-03;122(3):473-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  446. Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
    Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
    J. Neuroimmunol., 2009-02-01;208(1):54-60.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  447. Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.
    Authors: Caruso R, Stolfi C, Sarra M, Rizzo A, Fantini MC, Pallone F, MacDonald TT, Monteleone G
    Blood, 2009-01-07;113(15):3512-9.
    Species: Mouse
    Sample Types: Serum
  448. Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia.
    Authors: Rosenberger P, Schwab JM, Mirakaj V, Masekowsky E, Mager A, Morote-Garcia JC, Unertl K, Eltzschig HK
    Nat. Immunol., 2009-01-04;10(2):195-202.
    Species: Mouse
    Sample Types: Serum
  449. p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia.
    Authors: Liu Q, Cheng LI, Yi L, Zhu N, Wood A, Changpriroa CM, Ward JM, Jackson SH
    Am. J. Pathol., 2008-12-18;174(1):153-63.
    Species: Mouse
    Sample Types: BALF
  450. NOD1 expression in the eye and functional contribution to IL-1beta-dependent ocular inflammation in mice.
    Authors: Rosenzweig HL, Galster KT, Planck SR, Rosenbaum JT
    Invest. Ophthalmol. Vis. Sci., 2008-12-13;50(4):1746-53.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  451. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
    Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
    Int. Immunol., 2008-12-09;21(1):81-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  452. Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
    Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2008-09-17;75(1):52-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  453. Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
    Authors: Zhang H, Moochhala SM, Bhatia M
    J. Immunol., 2008-09-15;181(6):4320-31.
    Species: Mouse
    Sample Types: Tissue Homogenates
  454. Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
    Authors: Leoni G, Patel HB, Sampaio AL, Gavins FN, Murray JF, Grieco P, Getting SJ, Perretti M
    FASEB J., 2008-08-29;22(12):4228-38.
    Species: Mouse
    Sample Types: Plasma
  455. Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.
    Authors: Paul R, Obermaier B, Van Ziffle J, Angele B, Pfister HW, Lowell CA, Koedel U
    J. Leukoc. Biol., 2008-07-14;84(4):1141-50.
    Species: Mouse
    Sample Types: Tissue Homogenates
  456. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
    Authors: Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT
    Nat. Immunol., 2008-07-11;9(8):857-65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  457. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
    Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
    Eur. J. Pharmacol., 2008-06-16;590(1):400-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  458. The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
    Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
    J. Immunol., 2008-06-15;180(12):8333-41.
    Species: Mouse
    Sample Types: Tissue Homogenates
  459. Purine receptor antagonist modulates serology and affective behaviors in lupus-prone mice: evidence of autoimmune-induced pain?
    Authors: Ballok DA, Sakic B
    Brain Behav. Immun., 2008-06-14;0(0):.
    Species: Mouse
    Sample Types: Serum
  460. Activation of NOD2 in vivo induces IL-1beta production in the eye via caspase-1 but results in ocular inflammation independently of IL-1 signaling.
    Authors: Rosenzweig HL, Martin TM, Planck SR, Galster K, Jann MM, Davey MP, Kobayashi K, Flavell RA, Rosenbaum JT
    J. Leukoc. Biol., 2008-05-21;84(2):529-36.
    Species: Mouse
    Sample Types: Tissue Homogenates
  461. Functional roles for C5a receptors in sepsis.
    Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
    Nat. Med., 2008-05-04;14(5):551-7.
    Species: Mouse
    Sample Types: Plasma
  462. Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice.
    Authors: Doverhag C, Keller M, Karlsson A, Hedtjarn M, Nilsson U, Kapeller E, Sarkozy G, Klimaschewski L, Humpel C, Hagberg H, Simbruner G, Gressens P, Savman K
    Neurobiol. Dis., 2008-04-25;31(1):133-44.
    Species: Mouse
    Sample Types: Tissue Homogenates
  463. Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages.
    Authors: Pae HO, Jeong SO, Koo BS, Ha HY, Lee KM, Chung HT
    Biochem. Biophys. Res. Commun., 2008-04-22;371(3):361-5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  464. CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation.
    Authors: Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG, Kim YM
    Biochem. Pharmacol., 2008-04-18;76(1):79-90.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  465. Adverse functions of IL-17A in experimental sepsis.
    Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
    FASEB J., 2008-02-25;22(7):2198-205.
    Species: Mouse
    Sample Types: Plasma
  466. Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics.
    Authors: Umemura N, Saio M, Suwa T, Kitoh Y, Bai J, Nonaka K, Ouyang GF, Okada M, Balazs M, Adany R, Shibata T, Takami T
    J. Leukoc. Biol., 2008-02-19;83(5):1136-44.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  467. Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
    Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
    Nat. Med., 2008-02-03;14(2):199-204.
    Species: Mouse
    Sample Types: BALF
  468. Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
    Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
    J. Immunol., 2008-01-01;180(1):609-17.
    Species: Mouse
    Sample Types: Tissue Secretion
  469. Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
    Authors: Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR
    Transplantation, 2007-11-27;84(10):1279-87.
    Species: Mouse
    Sample Types: Serum
  470. Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk.
    Authors: Ryu M, Kim EH, Chun M, Kang S, Shim B, Yu YB, Jeong G, Lee JS
    J Ethnopharmacol, 2007-10-05;115(2):184-93.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  471. Maternal immune activation alters fetal brain development through interleukin-6.
    Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
    J. Neurosci., 2007-10-03;27(40):10695-702.
    Species: Mouse
    Sample Types: Serum
  472. Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
    Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
    Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4498-508.
    Species: Mouse
    Sample Types: Tissue Homogenates
  473. ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
    Authors: Huang X, Du W, Barrett RP, Hazlett LD
    Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4626-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  474. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.
    Authors: Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J
    Nat. Med., 2007-09-02;13(9):1042-9.
    Species: Mouse
    Sample Types: Serum
  475. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
    Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
    Crit. Care Med., 2007-08-01;35(8):1955-60.
    Species: Mouse
    Sample Types: Plasma
  476. Neuronal NF-kappaB influences thermoregulation and survival in a sepsis model.
    Authors: Juttler E, Inta I, Eigler V, Herrmann O, Maegele I, Maser-Gluth C, Schwaninger M
    J. Neuroimmunol., 2007-07-25;189(1):41-9.
    Species: Mouse
    Sample Types: Serum
  477. Acute brain injury triggers MyD88-dependent, TLR2/4-independent inflammatory responses.
    Authors: Koedel U, Merbt UM, Schmidt C, Angele B, Popp B, Wagner H, Pfister HW, Kirschning CJ
    Am. J. Pathol., 2007-07-01;171(1):200-13.
    Species: Mouse
    Sample Types: Tissue Homogenates
  478. Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
    Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007-06-01;293(2):L491-6.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  479. Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi.
    Authors: Medeiros MM, Peixoto JR, Oliveira AC, Cardilo-Reis L, Koatz VL, Van Kaer L, Previato JO, Mendonca-Previato L, Nobrega A, Bellio M
    J. Leukoc. Biol., 2007-05-31;82(3):488-96.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  480. Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
    Authors: Nguyen M, Pace AJ, Koller BH
    J. Exp. Med., 2007-05-21;204(6):1383-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  481. The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
    Authors: Fujita H, Asahina A, Komine M, Tamaki K
    Cell. Immunol., 2007-05-15;245(2):70-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  482. Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior.
    Authors: Lowry CA, Hollis JH, de Vries A, Pan B, Brunet LR, Hunt JR, Paton JF, van Kampen E, Knight DM, Evans AK, Rook GA, Lightman SL
    Neuroscience, 2007-03-23;146(2):756-72.
    Species: Mouse
    Sample Types: Plasma
  483. Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
    Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
    Am. J. Pathol., 2007-03-01;170(3):1003-17.
    Species: Mouse
    Sample Types: Serum
  484. Cell-based angiopoietin-1 gene therapy for acute lung injury.
    Authors: McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ
    Am. J. Respir. Crit. Care Med., 2007-02-22;175(10):1014-26.
    Species: Mouse
    Sample Types: BALF
  485. The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
    Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
    Life Sci., 2007-02-03;80(20):1821-31.
    Species: Mouse
    Sample Types: BALF
  486. The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.
    Authors: Chang CP, Huang WT, Cheng BC, Hsu CC, Lin MT
    Neuropharmacology, 2007-01-03;52(3):1024-33.
    Species: Mouse
    Sample Types: Serum
  487. Tetrathiomolybdate is effective in a mouse model of arthritis.
    Authors: McCubbin MD, Hou G, Abrams GD, Dick R, Brewer GJ
    J. Rheumatol., 2006-10-15;33(12):2501-6.
    Species: Mouse
    Sample Types: Serum
  488. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
    Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2006-10-11;70(11):1942-7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  489. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
    Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
    Arthritis Rheum., 2006-10-01;54(10):3182-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  490. Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells.
    Authors: Deng L, Dai P, Ding W, Granstein RD, Shuman S
    J. Virol., 2006-10-01;80(20):9977-87.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  491. CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
    Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
    Int. Immunol., 2006-09-11;18(11):1531-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  492. [D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse).
    Authors: Getting SJ, Lam CW, Leoni G, Gavins FN, Grieco P, Perretti M
    Mol. Pharmacol., 2006-09-07;70(6):1850-5.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  493. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
    Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006-08-04;291(6):L1246-55.
    Species: Mouse
    Sample Types: Tissue Homogenates
  494. Allergic airway inflammation inhibits pulmonary antibacterial host defense.
    Authors: Beisswenger C, Kandler K, Hess C, Garn H, Felgentreff K, Wegmann M, Renz H, Vogelmeier C, Bals R
    J. Immunol., 2006-08-01;177(3):1833-7.
    Species: Mouse
    Sample Types: BALF
  495. Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation.
    Authors: Card JW, Carey MA, Bradbury JA, DeGraff LM, Morgan DL, Moorman MP, Flake GP, Zeldin DC
    J. Immunol., 2006-07-01;177(1):621-30.
    Species: Mouse
    Sample Types: BALF
  496. Organ-specific role of MyD88 for gene regulation during polymicrobial peritonitis.
    Authors: Weighardt H, Mages J, Jusek G, Kaiser-Moore S, Lang R, Holzmann B
    Infect. Immun., 2006-06-01;74(6):3618-32.
    Species: Mouse
    Sample Types: Tissue Homogenates
  497. Absence of IL-1 receptor antagonist impaired wound healing along with aberrant NF-kappaB activation and a reciprocal suppression of TGF-beta signal pathway.
    Authors: Ishida Y, Kondo T, Kimura A, Matsushima K, Mukaida N
    J. Immunol., 2006-05-01;176(9):5598-606.
    Species: Mouse
    Sample Types: Tissue Homogenates
  498. Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung.
    Authors: Andre E, Stoeger T, Takenaka S, Bahnweg M, Ritter B, Karg E, Lentner B, Reinhard C, Schulz H, Wjst M
    Eur. Respir. J., 2006-04-26;28(2):275-85.
    Species: Mouse
    Sample Types: BALF
  499. Protease-activated receptor-2 activation: a major role in the pathogenesis of Porphyromonas gingivalis infection.
    Authors: Holzhausen M, Spolidorio LC, Ellen RP, Jobin MC, Steinhoff M, Andrade-Gordon P, Vergnolle N
    Am. J. Pathol., 2006-04-01;168(4):1189-99.
    Species: Mouse
    Sample Types: Blister Fluid
  500. Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters.
    Authors: Li RW, Theriault AG, Au K, Douglas TD, Casaschi A, Kurowska EM, Mukherjee R
    Life Sci., 2006-02-21;79(4):365-73.
    Species: Mouse
    Sample Types: Serum
  501. Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
    Authors: Weijer S, Florquin S, van der Poll T
    Shock, 2005-01-01;23(1):54-8.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  502. The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
    Authors: Cotena A, Platt N
    J. Immunol., 2004-11-15;173(10):6427-32.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  503. Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes.
    Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF
    Comp. Immunol. Microbiol. Infect. Dis., 2004-11-01;27(6):393-411.
    Species: Mouse
    Sample Types: Serum
  504. IL-1 receptor-associated kinase 1 mediates protection against Staphylococcus aureus infection.
    Authors: Verdrengh M, Thomas JA, Hultgren OH
    Microbes Infect., 2004-11-01;6(14):1268-72.
    Species: Mouse
    Sample Types: Serum
  505. Cytokine expression in experimental chronic otitis media with effusion in mice.
    Authors: Maeda K, Hirano T, Ichimiya I, Kurono Y, Suzuki M, Mogi G
    Laryngoscope, 2004-11-01;114(11):1967-72.
    Species: Mouse
    Sample Types: Tissue Secretion
  506. Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
    Authors: Thakur A, Barrett RP, McClellan S, Hazlett LD
    Curr. Eye Res., 2004-10-01;29(4):225-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  507. Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts.
    Authors: Tanaka M, Terry RD, Mokhtari GK, Inagaki K, Koyanagi T, Kofidis T, Mochly-Rosen D, Robbins RC
    Circulation, 2004-09-14;110(11):II194-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  508. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
    Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
    J. Exp. Med., 2004-05-17;199(10):1355-65.
    Species: Mouse
    Sample Types: Serum
  509. Responses of guinea pig pups during isolation in a novel environment may represent stress-induced sickness behaviors.
    Authors: Hennessy MB, Deak T, Schiml-Webb PA, Wilson SE, Greenlee TM, McCall E
    Physiol. Behav., 2004-03-01;81(1):5-13.
    Species: Guinea Pig
    Sample Types: Serum
  510. Systemic up-regulation of sTNFR2 and IL-6 in Porphyromonas gingivalis pneumonia in mice.
    Authors: Petelin M, Naruishi K, Shiomi N, Mineshiba J, Arai H, Nishimura F, Takashiba S, Murayama Y
    Exp. Mol. Pathol., 2004-02-01;76(1):76-81.
    Species: Mouse
    Sample Types: Serum
  511. Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
    Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
    Blood, 2003-10-30;103(5):1702-9.
    Species: Mouse
    Sample Types: BALF
  512. Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
    Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
    Infect. Immun., 2003-04-01;71(4):2276-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  513. Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor.
    Authors: Getting SJ, Christian HC, Lam CW, Gavins FN, Flower RJ, Schioth HB, Perretti M
    J. Immunol., 2003-03-15;170(6):3323-30.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  514. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
    Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
    J. Immunol., 2003-02-15;170(4):2106-12.
    Species: Mouse
    Sample Types: BALF
  515. Caspase-1-deficient mice have delayed neutrophil apoptosis and a prolonged inflammatory response to lipopolysaccharide-induced acute lung injury.
    Authors: Rowe SJ, ECfDá, Allen L, Ridger VC, Hellewell PG, Whyte MK
    2002-12-01;169(11):6401-7.
    Species: Mouse
    Sample Types: BALF
  516. The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
    Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
    Eur. J. Immunol., 2001-07-01;31(7):2104-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  517. Dendritic cells phagocytose and are activated by Treponema pallidum.
    Authors: Bouis DA, Popova TG, Takashima A, Norgard MV
    Infect. Immun., 2001-01-01;69(1):518-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  518. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia.
    Authors: Yates SL, Burgess LH, Kocsis-Angle J, Antal JM, Dority MD, Embury PB, Piotrkowski AM, Brunden KR
    J. Neurochem., 2000-03-01;74(3):1017-25.
    Species: Mouse
    Sample Types: Cell Culture Supernates

FAQs

  1. Does the Mouse IL-1 beta/IL-1F2 Quantikine ELISA (Catalog # MLB00C) cross-react with the pro-form of Mouse IL-1 beta?

    • The Mouse IL-1 beta/IL-1F2 Quantikine ELISA is designed to detect mature mouse IL-1 beta and the assay is calibrated against recombinant mouse IL-1 beta. It is possible that the kit also detects the pro-form, however, R&D Systems has not performed this characterization.

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Reviews for Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit

Average Rating: 4.8 (Based on 19 Reviews)

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Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 09/29/2024
Sample Tested: mouse brain lysate
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 10/18/2023
Sample Tested: Serum
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Sergi Bayod on 11/21/2022
Sample Tested: EDTA Plasma

Undiluted mouse plasma samples

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 08/28/2022
Sample Tested: Cell culture supernatant,Serum

Easy perform and works great!

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 06/08/2022
Sample Tested: Serum-free Cell Culture Media
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 12/21/2021
Sample Tested: moues cell line conditioned media
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 06/07/2021
Sample Tested: Serum

Mouse serum

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 07/26/2020
Sample Tested: bone marrow
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 02/11/2020
Sample Tested: Mouse pancreas
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 10/17/2019
Sample Tested: Brain (hypothalamus) tissue,Brainstem tissue
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 09/21/2019
Sample Tested: Brain (hippocampus),Serum

Hippocampus: sensitivity is good for detection of samples with dilution not more than 4X.

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 06/20/2019
Sample Tested: Embryonic cortical glial cells
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 05/22/2019
Sample Tested: Mouse Lung BALF

Highly sensitive ELISA very easy to work with. Don't normally dilute samples.

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 04/10/2019
Sample Tested: EDTA Plasma
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 03/12/2019
Sample Tested: Serum
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 02/19/2019
Sample Tested: Adult brain (hippocampus),Brain (cerebral cortex),Brain (hypothalamus) tissue,Striatum

One of the best ELISA kits for interleukin- 1 beta estimation. I have used kits from 2 other vendors but the reproducibility with this kit is uncomparable. I am blindly thinking of RnD systems from my ELISA requirements after using this kit.

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 05/08/2018
Sample Tested: Heparin Plasma

Among best ELISAs I've worked with. Great consistency lot to lot, high sensitivity, easy to work with small amount of samples (usually dilute mouse plasma 1:10). Appropriate for concentration response curves.

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 12/04/2017
Sample Tested: Cell culture supernatant

highly recommend.

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Jim Hsiao on 03/07/2017
Sample Tested: Cell culture supernatant,Mouse Primary Monocytes
Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C