Mouse IL-10 DuoSet ELISA Summary
* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.
This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse IL-10. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.
Product Features
- Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
- Development protocols are provided to guide further assay optimization
- Assay can be customized to your specific needs
- Economical alternative to complete kits
Kit Content
- Capture Antibody
- Detection Antibody
- Recombinant Standard
- Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)
Other Reagents Required
DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.
The components listed above may be purchased separately:
PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered
Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4
Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered
Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)
Stop Solution: 2 N H2SO4 (Catalog # DY994)
Microplates: R&D Systems (Catalog # DY990)
Plate Sealers: ELISA Plate Sealers (Catalog # DY992)
Scientific Data
Product Datasheets
Preparation and Storage
Background: IL-10
Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is the charter member of the IL-10 alpha -helical cytokine family that also includes IL-19, IL-20, IL-22, IL-24, and IL-26/AK155 (1-3). IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts. Whereas human IL-10 is active on mouse cells, mouse IL-10 does not act on human cells (4, 5). Mature mouse IL-10 shares 85% amino acid sequence identity with rat IL-10 and 70-77% with bovine, canine, equine, feline, human, ovine, and porcine IL-10. It contains two intrachain disulfide bridges and is expressed as a 36 kDa noncovalently-associated homodimer (4, 6, 7).
Assay Procedure
GENERAL ELISA PROTOCOL
Plate Preparation
- Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
- Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
- Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
- Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.
Assay Procedure
- Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Repeat the aspiration/wash as in step 2.
- Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
- Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.
Citations for Mouse IL-10 DuoSet ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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The potential therapeutic role of itaconate and mesaconate on the detrimental effects of LPS-induced neuroinflammation in the brain
Authors: Ohm, M;Hosseini, S;Lonnemann, N;He, W;More, T;Goldmann, O;Medina, E;Hiller, K;Korte, M;
Journal of neuroinflammation
Species: Mouse
Sample Types: Cell Culture Supernates
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H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses in vitro
Authors: Gabele, L;Bochow, I;Rieke, N;Sieben, C;Michaelsen-Preusse, K;Hosseini, S;Korte, M;
Frontiers in cellular neuroscience
Species: Mouse
Sample Types: Cell Culture Supernates
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Rujin Jiedu decoction protects against influenza virus infection by modulating gut microbiota
Authors: Huang, Q;Yang, G;Tang, C;Dou, B;Hu, Y;Liu, H;Wu, X;Zhang, H;Wang, H;Xu, L;Yang, XD;Xu, Y;Zheng, Y;
Heliyon
Species: Mouse
Sample Types: Cell Culture Supernates
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Acute effects of atrazine on the immunoexpressions of Sertoli and germ cells molecular markers, cytokines, chemokines, and sex hormones levels in mice testes and epididymides
Authors: Abarikwu, SO;Coimbra, JLP;Campolina-Silva, G;Rocha, ST;Costa, VV;Lacerda, SMSN;Costa, GMJ;
Chemosphere
Species: Mouse
Sample Types: Tissue Homogenates
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Malaria transmission blocking activity of Anopheles stephensi alanyl aminopeptidase N antigen formulated with MPL, CpG, and QS21 adjuvants
Authors: Pourhashem, Z;Nourani, L;Pirahmadi, S;Yousefi, H;J Sani, J;Raz, A;Zakeri, S;Dinparast Djadid, N;Abouie Mehrizi, A;
PloS one
Species: Mouse
Sample Types: Cell Culture Supernates
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Absence of c-Maf and IL-10 enables Type I IFN enhancement of innate responses to low-dose LPS in alveolar macrophages
Authors: Lim, PN;Cervantes, MM;Pham, LK;Doherty, S;Tufts, A;Dubey, D;Mai, D;Aderem, A;Diercks, AH;Rothchild, AC;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Cell Culture Supernates
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Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice
Authors: Alves, M;Gil, B;Villegas-Salmerón, J;Salari, V;Martins-Ferreira, R;Arribas Blázquez, M;Menéndez Méndez, A;Da Rosa Gerbatin, R;Smith, J;de Diego-Garcia, L;Conte, G;Sierra-Marquez, J;Merino Serrais, P;Mitra, M;Fernandez Martin, A;Wang, Y;Kesavan, J;Melia, C;Parras, A;Beamer, E;Zimmer, B;Heiland, M;Cavanagh, B;Parcianello Cipolat, R;Morgan, J;Teng, X;Prehn, JHM;Fabene, PF;Bertini, G;Artalejo, AR;Ballestar, E;Nicke, A;Olivos-Oré, LA;Connolly, NMC;Henshall, DC;Engel, T;
Brain, behavior, and immunity
Species: Transgenic Mouse
Sample Types: Tissue Homogenates
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Electrical stimulation of the dorsal motor nucleus of the vagus in male mice can regulate inflammation without affecting the heart rate
Authors: Falvey, A;Palandira, SP;Chavan, SS;Brines, M;Dantzer, R;Tracey, KJ;Pavlov, VA;
Brain, behavior, and immunity
Species: Mouse
Sample Types: Serum, Tissue Homogenates
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Mesenchymal Stem/Stromal Cells Induce Myeloid-Derived Suppressor Cells in the Bone Marrow via the Activation of the c-Jun N-Terminal Kinase Signaling Pathway
Authors: Lee, HJ;Oh, JY;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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Arsenic trioxide alleviates atherosclerosis by inhibiting CD36-induced endocytosis and TLR4/NF-?B-induced inflammation in macrophage and ApoE-/- mice
Authors: Li, Z;Zou, X;Lu, R;Wan, X;Sun, S;Wang, S;Qu, Y;Zhang, Y;Li, Z;Yang, L;Fang, S;
International immunopharmacology
Species: Mouse
Sample Types: Serum
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IFN-?3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans
Authors: De, M;Sukla, S;Bharatiya, S;Keshri, S;Roy, DG;Roy, S;Dutta, D;Saha, S;Ejazi, SA;Ravichandiran, V;Ali, N;Chatterjee, M;Chinnaswamy, S;
Infection and immunity
Species: Mouse
Sample Types: Serum, Cell Culture Supernates
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Reprogramming Short-Chain Fatty Acid Metabolism Mitigates Tissue Damage for Streptococcus pyogenes Necrotizing Skin Infection
Authors: Caparon, M;Xu, W;Bradstreet, T;Zou, Z;Hickerson, S;Zhou, Y;He, H;Edelson, B;
Research square
Species: Mouse
Sample Types: Cell Culture Supernates
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Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization
Authors: Yang, Y;Gao, ZF;Hou, GG;Meng, QG;Hou, Y;
European journal of medicinal chemistry
Species: Mouse
Sample Types: Cell Culture Supernates
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Protein Concentration Affects the Food Allergen ?-Conglutin Uptake and Bacteria-Induced Cytokine Production in Dendritic Cells
Authors: Heinzl, GC;Eriksen, DB;Johnsen, PR;Scarafoni, A;Frøkiær, H;
Biomolecules
Species: Mouse
Sample Types: Cell Culture Supernates
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Effects of lysine deacetylase inhibitor treatment on LPS responses of alveolar-like macrophages
Authors: Russo, S;Kwiatkowski, M;Wolters, JC;Gerding, A;Hermans, J;Govorukhina, N;Bischoff, R;Melgert, BN;
Journal of leukocyte biology
Species: Mouse
Sample Types: Serum, Urine
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A 5-Lipoxygenase Inhibitor, Zileuton, Modulates Host Immune Responses and Improves Lung Function in a Model of Severe Acute Respiratory Syndrome (SARS) Induced by Betacoronavirus
Authors: Pereira, RDD;Rabelo, RAN;Oliveira, NFM;Porto, SLT;Andrade, ACDSP;Queiroz-Junior, CM;Barbosa, CLN;de Souza-Costa, LP;Santos, FRDS;Oliveira, FBR;da Silva, BLV;Umezu, HL;Ferreira, R;da Silva, GSF;Cruz, JS;Teixeira, MM;Costa, VV;Machado, FS;
Viruses
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Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice
Authors: Schädel, P;Wichmann-Costaganna, M;Czapka, A;Gebert, N;Ori, A;Werz, O;
Nutrients
Species: Mouse
Sample Types: Tissue Homogenates
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Aspirin synergizes with mineral particle-coated macroporous scaffolds for bone regeneration through immunomodulation
Authors: Su, N;Villicana, C;Zhang, C;Lee, J;Sinha, S;Yang, A;Yang, F;
Theranostics
Species: Mouse
Sample Types: Cell Culture Supernates
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Adenosine metabolized from extracellular ATP ameliorates organ injury by triggering A2BR signaling
Authors: Kelestemur, T;Németh, ZH;Pacher, P;Beesley, J;Robson, SC;Eltzschig, HK;Haskó, G;
Respiratory research
Species: Mouse
Sample Types: Plasma
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Central carbon flux controls growth/damage balance for Streptococcus pyogenes
Authors: Merriman, JA;Xu, W;Caparon, MG;
PLoS pathogens
Species: Mouse
Sample Types: Cell Culture Supernates
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Obesity-induced hyperglycemia impairs oral tolerance induction and aggravates food allergy
Authors: Torres, L;Camila Gonçalves Miranda, M;Dantas Martins, V;Caixeta, F;de Almeida Oliveira, M;Martins Trindade, L;Carvalho de Assis, H;Nascimento, V;Pinheiro Rosa, N;Gomes, E;Oliveira Almeida, S;Marquet, F;Genser, L;Marcelin, G;Clément, K;Russo, M;Maria Caetano Faria, A;Uceli Maioli, T;
Mucosal immunology
Species: Mouse
Sample Types: Feces
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TREM2 expression on the microglia resolved lead exposure-induced neuroinflammation by promoting anti-inflammatory activities
Authors: Su, P;Zhang, J;Wu, J;Chen, H;Luo, W;Hu, M;
Ecotoxicology and environmental safety
Species: Mouse
Sample Types: Cell Culture Supernates
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Electrical stimulation of the dorsal motor nucleus of the vagus regulates inflammation without affecting the heart rate
Authors: Falvey, A;Palandira, SP;Chavan, SS;Brines, M;Tracey, KJ;Pavlov, VA;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Serum, Tissue Homogenates
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Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging
Authors: P Schädel, A Czapka, N Gebert, ID Jacobsen, A Ori, O Werz
Aging Cell, 2023-04-26;0(0):e13856.
Species: Mouse
Sample Types: Cell Culture Supernates
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Macrophage fumarate hydratase restrains mtRNA-mediated interferon production
Authors: A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, EN Montano, L Huo, JE Toller-Kaw, V Zecchini, TAJ Ryan, A Bolado-Car, AM Casey, HA Prag, ASH Costa, G De Los San, M Ishimori, DJ Wallace, S Venuturupa, E Nikitopoul, N Frizzell, C Johansson, A Von Kriegs, MP Murphy, C Jefferies, C Frezza, LAJ O'Neill
Nature, 2023-03-08;615(7952):490-498.
Species: Transgenic Mouse, Mouse
Sample Types: Cell Culture Supernates
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Ageing-Induced Decline in Primary Myeloid Cell Phagocytosis Is Unaffected by Optineurin Insufficiency
Authors: J Peradinovi, N Mohovic, K Bulic, A Markovinov, R Cimbro, I Munitic
Biology, 2023-02-03;12(2):.
Species: Transgenic Mouse
Sample Types: Cell Culture Supernates
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Investigation of the Effects of Monomeric and Dimeric Stilbenoids on Bacteria-Induced Cytokines and LPS-Induced ROS Formation in Bone Marrow-Derived Dendritic Cells
Authors: PR Johnsen, C Pinna, L Mattio, MB Strube, M Di Nunzio, S Iametti, S Dallavalle, A Pinto, H Frøkiær
International Journal of Molecular Sciences, 2023-02-01;24(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Dendritic cell-expressed IDO alleviates atherosclerosis by expanding CD4+CD25+Foxp3+Tregs through IDO-Kyn-AHR axis
Authors: F Wang, M Liu, D Ma, Z Cai, L Liu, J Wang, W Zhang, L Zhao, C Zhai, Y Xu
International immunopharmacology, 2023-01-26;116(0):109758.
Species: Mouse
Sample Types: Cell culture supernate
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Effects of mesenchymal stem cell-derived nanovesicles in experimental allergic airway inflammation
Authors: E Bandeira, SC Jang, C Lässer, K Johansson, M Rådinger, KS Park
Respiratory Research, 2023-01-05;24(1):3.
Species: Mouse
Sample Types: Cell Culture Supernates
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Trypanosoma brucei rhodesiense Inhibitor of Cysteine Peptidase (ICP) Is Required for Virulence in Mice and to Attenuate the Inflammatory Response
Authors: TFR Costa, A Goundry, A Morrot, DJ Grab, JC Mottram, APCA Lima
International Journal of Molecular Sciences, 2022-12-30;24(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Is the production of reactive oxygen and nitrogen species by macrophages associated with better infectious control in female mice with experimentally disseminated and pulmonary mucormycosis?
Authors: ARD Santos, TF Fraga-Silv, DF Almeida-Do, AC Finatto, C Marchetti, MI Andrade, OS Arruda, MSP Arruda, J Venturini
PLoS ONE, 2022-12-15;17(12):e0270071.
Species: Mouse
Sample Types: Cell Culture Supernates
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EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis
Authors: JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park
Arthritis Research & Therapy, 2022-11-17;24(1):254.
Species: Mouse
Sample Types: Serum
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PD-1/PD-L1 inhibition enhances chemotherapy-induced neuropathic pain by suppressing neuroimmune antinociceptive signaling
Authors: CWS Wanderley, A Maganin, B Adjafre, AS Mendes, CE Anibal Sil, AU Quadros, JPM Luiz, CMS Silva, NR Silva, FF Oliveira, FIF Gomes, JLJ Restrepo, CA Speck-Hern, F Turaça, GVL Silva, GR Pigatto, HI Nakaya, JM Mota, R Barroso-So, JC Alves-Filh, TM Cunha, FQ Cunha
Cancer Immunology Research, 2022-11-02;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cationic Polyethyleneimine (PEI)-Gold Nanocomposites Modulate Macrophage Activation and Reprogram Mouse Breast Triple-Negative MET-1 Tumor Immunological Microenvironment
Authors: V Mulens-Ari, A Nicolás-Bo, F Carn, F Gazeau
Pharmaceutics, 2022-10-19;14(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance
Authors: H Wang, Y Li, Z Yue, Y Liu, Q Chen, D Hu, J Han
BioMed Research International, 2022-10-12;2022(0):9899135.
Species: Mouse
Sample Types: Tissue Homogenates
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Inhaled delivery of recombinant interferon-lambda restores allergic inflammation after development of asthma by controlling Th2- and Th17-cell-mediated immune responses
Authors: J Won, A Jo, CH Gil, S Kim, H Shin, H Jik Kim
International immunopharmacology, 2022-08-27;112(0):109180.
Species: Mouse
Sample Types: BALF
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Extracellular matrix of early pulmonary fibrosis modifies the polarization of alveolar macrophage
Authors: Y Zhang, L Zhu, J Hong, C Chen
International immunopharmacology, 2022-08-24;111(0):109179.
Species: Mouse
Sample Types: Cell Culture Supernates
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Promotion of neutralizing antibody-independent immunity to wild-type and SARS-CoV-2 variants of concern using an RBD-Nucleocapsid fusion protein
Authors: JT Castro, P Azevedo, MJ Fumagalli, NS Hojo-Souza, N Salazar, GG Almeida, LI Oliveira, L Faustino, LR Antonelli, TG Marçal, M Augusto, B Valiate, A Fiorini, B Rattis, SG Ramos, M Piccin, OC Nonato, L Benevides, R Magalhães, B Cassaro, G Burle, D Doro, J Kalil, E Durigon, A Salazar, O Caballero, H Santiago, A Machado, JS Silva, F da Fonseca, AP Fernandes, SR Teixeira, RT Gazzinelli
Nature Communications, 2022-08-17;13(1):4831.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cluster of Differentiation 147 (CD147) serves as a promoter of atherosclerosis in patients with cerebral infarction
Authors: GJ Wang, X Dong, Y Li
European review for medical and pharmacological sciences, 2022-08-01;26(16):5710-5717.
Species: Human
Sample Types: Serum
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In vitro and in vivo Characterization of Host-Pathogen Interactions of the L3881 Candida albicans Clinical Isolate
Authors: PHF Sucupira, TR Moura, ILS Gurgel, TTP Pereira, ACB Padovan, MM Teixeira, D Bahia, FM Soriani
Frontiers in Microbiology, 2022-07-11;13(0):901442.
Species: Mouse
Sample Types: Cell Culture Supernates
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Mechanism of antifungal activity and therapeutic action of beta-ionone on Aspergillus fumigatus keratitis via suppressing LOX1 and JNK/p38 MAPK activation
Authors: M Yin, C Li, L Zhang, L Zhang, J Lin, N Jiang, Q Wang, Q Xu, H Zheng, L Gu, Y Jia, B Yu, G Zhao
International immunopharmacology, 2022-07-07;110(0):108992.
Species: Mouse
Sample Types: Tissue Homogenates
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Staphylococcus aureus-induced immunosuppression mediated by IL-10 and IL-27 facilitates nasal colonisation
Authors: AM Kelly, JM Leech, SL Doyle, RM McLoughlin
PloS Pathogens, 2022-07-01;18(7):e1010647.
Species: Mouse
Sample Types: Cell Culture Supernates
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Aspirin-Triggered Resolvin D1 Reduces Chronic Dust-Induced Lung Pathology without Altering Susceptibility to Dust-Enhanced Carcinogenesis
Authors: EC Dominguez, R Phandthong, M Nguyen, A Ulu, S Guardado, S Sveiven, P Talbot, TM Nordgren
Cancers, 2022-04-09;14(8):.
Species: Mouse
Sample Types: Bronchoalveolar lavage fluid
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The Secretome of Preconditioned Mesenchymal Stem Cells Drives Polarization and Reprogramming of M2a Macrophages toward an IL-10-Producing Phenotype
Authors: M Holthaus, N Santhakuma, T Wahlers, A Paunel-Gör
International Journal of Molecular Sciences, 2022-04-07;23(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice
Authors: YH Su, JY Lin
International Journal of Molecular Sciences, 2022-04-04;23(7):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cathepsin D interacts with adenosine A2A receptors in mouse macrophages to modulate cell surface localization and inflammatory signaling
Authors: A Skopál, T Kéki, PÁ Tóth, B Csóka, B Koscsó, ZH Német, L Antonioli, A Ivessa, F Ciruela, L Virág, G Haskó, E Kókai
The Journal of Biological Chemistry, 2022-03-31;0(0):101888.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model
Authors: J Zhu, T Inomata, M Nakamura, K Fujimoto, Y Akasaki, K Fujio, A Yanagawa, K Uchida, J Sung, N Negishi, K Nagino, Y Okumura, M Miura, H Shokirova, M Kuwahara, K Hirosawa, A Midorikawa, A Eguchi, T Huang, H Yagita, S Habu, K Okumura, A Murakami
Scientific Reports, 2022-03-22;12(1):4853.
Species: Mouse
Sample Types: Cell Culture Supernates
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Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages
Authors: XAMH van Dieren, F Vrieling, L Smeehuijze, L Deng, JP Boogaard, CA Croes, L Temmerman, S Wetzels, E Biessen, S Kersten, R Stienstra
Proceedings of the National Academy of Sciences of the United States of America, 2022-03-18;119(12):e2114739119.
Species: Mouse
Sample Types: Cell Culture Supernates
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The phosphoinositide-3-kinase (PI3K)-delta inhibitor seletalisib impairs monocyte-derived dendritic cells maturation, APC function, and promotes their migration to CCR7 and CXCR4 ligands
Authors: F Scopelliti, L Mercurio, C Cattani, V Dimartino, C Albanesi, G Costanzo, C Mirisola, S Madonna, A Cavani
Journal of leukocyte biology, 2022-02-24;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Immunogenic properties of empty pcDNA3 plasmid against zoonotic cutaneous leishmaniasis in mice
Authors: H Montakhab-, R Shafiei, M Najm, L Masoori, A Aspatwar, A Badirzadeh
PLoS ONE, 2022-02-15;17(2):e0263993.
Species: Mouse
Sample Types: Cell Culture Supernates
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Expression and Function of Nicotinic Acetylcholine Receptors in Induced Regulatory T Cells
Authors: Y Nakata, K Miura, N Yamasaki, S Ogata, S Miura, N Hosomi, O Kaminuma
International Journal of Molecular Sciences, 2022-02-04;23(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Clinical-like cryotherapy in acute knee arthritis of the knee improves inflammation signs, pain, joint swelling, and motor performance in mice
Authors: PATS Castro, GM Barbosa, DH Machanocke, RS Peres, TM Cunha, JE Cunha, FFB Oliveira, FS Ramalho, TL Russo, FQ Cunha, TF Salvini
PLoS ONE, 2022-01-21;17(1):e0261667.
Species: Mouse
Sample Types: Tissue Homogenates
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Glutaminolysis is required in maintaining immune regulatory functions in B cells
Authors: JQ Liu, XR Geng, TY Hu, LH Mo, XQ Luo, SY Qiu, DB Liu, ZG Liu, JB Shao, ZQ Liu, PC Yang
Mucosal Immunology, 2022-01-10;0(0):.
Species: Mouse
Sample Types: Nasal Secretion
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Intense Acute Swimming Induces Delayed-Onset Muscle Soreness Dependent on Spinal Cord Neuroinflammation
Authors: SM Borghi, SKD Bussulo, FA Pinho-Ribe, V Fattori, TT Carvalho, FS Rasquel-Ol, TH Zaninelli, CR Ferraz, AMB Casella, FQ Cunha, TM Cunha, R Casagrande, WA Verri
Frontiers in Pharmacology, 2022-01-07;12(0):734091.
Species: Mouse
Sample Types: Tissue Homogenates
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Metabolic Regulation of Macrophages by SIRT1 Determines Activation During Cholestatic Liver Disease in Mice
Authors: A Isaacs-Ten, M Moreno-Gon, C Bone, A Martens, F Bernuzzi, T Ludwig, C Hellmich, K Hiller, SA Rushworth, N Beraza
Cellular and Molecular Gastroenterology and Hepatology, 2021-12-22;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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The Role of Cytokines Produced via the NLRP3 Inflammasome in Mouse Macrophages Stimulated with Dental Calculus in Osteoclastogenesis
Authors: M Mae, MI Alam, Y Yamashita, Y Ozaki, K Higuchi, SM Ziauddin, JL Montenegro, E Sakai, T Tsukuba, A Yoshimura
International Journal of Molecular Sciences, 2021-11-18;22(22):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Restraint of Fumarate Accrual by HIF-1alpha Preserves miR-27a-Mediated Limitation of Interleukin 10 during Infection of Macrophages by Histoplasma capsulatum
Authors: HM Evans, DF Schultz, AJ Boiman, MC McKell, JE Qualls, GS Deepe
MBio, 2021-11-09;0(0):e0271021.
Species: Mouse
Sample Types: Cell Culture Supernates
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Sambucus nigra: A traditional medicine effective in reducing inflammation in mice
Authors: JR Santin, L Benvenutti, MF Broering, R Nunes, FC Goldoni, YBK Patel, JA de Souza, MAT Kopp, P de Souza, RCV da Silva, MVD Pastor, AB de Souza, LD Testoni, AG Couto, TMB Bresolin, NLM Quintão
Journal of ethnopharmacology, 2021-10-11;283(0):114736.
Species: Mouse
Sample Types: Cell Culture Supernates
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Limited role of the spleen in a mouse model of trained immunity: Impact on neutrophilia
Authors: AV Ferreira, RF Uijen, O Bulut, MI de Jonge, J Domínguez-, MG Netea
Journal of leukocyte biology, 2021-10-01;0(0):.
Species: Mouse
Sample Types: Serum
-
Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
Cell Reports, 2021-09-21;36(12):109726.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Expression of IL-20 Receptor Subunit beta Is Linked to EAE Neuropathology and CNS Neuroinflammation
Authors: JR Dayton, Y Yuan, LP Pacumio, BG Dorflinger, SC Yoo, MJ Olson, SI Hernández-, MM McMahon, L Cruz-Oreng
Frontiers in Cellular Neuroscience, 2021-09-07;15(0):683687.
Species: Mouse
Sample Types: Tissue Homogenates
-
Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection
Authors: G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi
PloS Biology, 2021-08-19;19(8):e3001387.
Species: Human
Sample Types: Plasma
-
Geographic differences in gut microbiota composition impact susceptibility to enteric infection
Authors: AM Porras, Q Shi, H Zhou, R Callahan, G Montenegro, N Solomons, IL Brito
Cell Reports, 2021-07-27;36(4):109457.
Species: Mouse
Sample Types: Tissue Supernates
-
Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs
Authors: L Benvenutti, R Nunes, I Venturi, SA Ramos, MF Broering, FC Goldoni, SE Pavan, MVD Pastor, A Malheiros, NLM Quintão, ES Fernandes, JR Santin
Journal of Immunology Research, 2021-07-19;2021(0):9957451.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Bifidobacterium breve Exopolysaccharide Blocks Dendritic Cell Maturation and Activation of CD4+ T Cells
Authors: A Hickey, P Stamou, S Udayan, A Ramón-Vázq, M Esteban-To, F Bottacini, JA Woznicki, O Hughes, S Melgar, M Ventura, D Van Sinder, V Rossini, K Nally
Frontiers in Microbiology, 2021-06-16;12(0):653587.
Species: Mouse
Sample Types: Cell Cultue Supernates
-
Ex Vivo-Induced Bone Marrow-Derived Myeloid Suppressor Cells Prevent Corneal Allograft Rejection in Mice
Authors: J Zhu, T Inomata, K Fujimoto, K Uchida, K Fujio, K Nagino, M Miura, N Negishi, Y Okumura, Y Akasaki, K Hirosawa, M Kuwahara, A Eguchi, H Shokirova, A Yanagawa, A Midorikawa, A Murakami
Investigative Ophthalmology & Visual Science, 2021-06-01;62(7):3.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Opisthorchis viverrini antigens up-regulates the expression of CD80 and MHC class II in JAWSII mouse dendritic cells and promotes IL-10 and TGF-&beta secretions
Authors: S Jittimanee, S Wongratana, C Kaewraemru, J Jittimanee
Parasitology international, 2021-05-31;84(0):102401.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia
Authors: J Wu, N Chen, Y Liu, G Godlewski, HJ Kaplan, SH Shrader, ZH Song, H Shao
PLoS ONE, 2021-05-13;16(5):e0251677.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Development of Delivery Systems Enhances the Potency of Cell-Based HIV-1 Therapeutic Vaccine Candidates
Authors: A Hadi, A Rastgoo, M Eskandaria, N Haghighipo, A Bolhassani
Journal of Immunology Research, 2021-04-20;2021(0):5538348.
Species: Mouse
Sample Types: Cell Culture Supernates
-
PDE9 Inhibitor PF-04447943 Attenuates DSS-Induced Colitis by Suppressing Oxidative Stress, Inflammation, and Regulating T-Cell Polarization
Authors: MN Rana, J Lu, E Xue, J Ruan, Y Liu, L Zhang, R Dhar, Y Li, Z Hu, J Zhou, W Ma, H Tang
Frontiers in Pharmacology, 2021-04-08;12(0):643215.
Species: Mouse
Sample Types: Tissue Homogenates
-
Combined Effects of Exercise and Phytoanabolic Extracts in Castrated Male and Female Mice
Authors: JP Martins, LC Silva, MS Nunes, G Rübensam, JR Oliveira, RBM Silva, MM Campos
Nutrients, 2021-04-02;13(4):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP
Authors: CS Umeshappa, P Solé, BGJ Surewaard, J Yamanouchi, S Mohapatra, MM Uddin, R Clarke, M Ortega, S Singha, D Mondal, Y Yang, DAA Vignali, P Serra, P Kubes, P Santamaria
Cell Reports, 2021-03-30;34(13):108919.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Hepatoprotective Effect of Mixture of Dipropyl Polysulfides in Concanavalin A-Induced Hepatitis
Authors: D Arsenijevi, B Stojanovic, J Milovanovi, A Arsenijevi, M Simic, M Pergal, I Kodranov, O Cvetkovic, D Vojvodic, E Ristanovic, D Manojlovic, M Milovanovi, N Arsenijevi
Nutrients, 2021-03-22;13(3):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bifidobacterium adolescentis Isolated from Different Hosts Modifies the Intestinal Microbiota and Displays Differential Metabolic and Immunomodulatory Properties in Mice Fed a High-Fat Diet
Authors: B Wang, Q Kong, S Cui, X Li, Z Gu, J Zhao, H Zhang, W Chen, G Wang
Nutrients, 2021-03-21;13(3):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Aryl hydrocarbon receptor (Ahr)-dependent Il-22 expression by type 3 innate lymphoid cells control of acute joint inflammation
Authors: R Nehmar, L Fauconnier, J Alves-Filh, D Togbe, A DeCauwer, S Bahram, M Le Bert, B Ryffel, P Georgel
Journal of Cellular and Molecular Medicine, 2021-03-18;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Silicone Oil-Based Nanoadjuvants as Candidates for a New Formulation of Intranasal Vaccines
Authors: A Razim, M Pyclik, K Pacyga, S Górska, J Xu, MA Olszewski, A Gamian, A Myc
Vaccines, 2021-03-08;9(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
Authors: JK Dowling, R Afzal, LJ Gearing, MP Cervantes-, S Annett, GM Davis, C De Santi, N Assmann, K Dettmer, DJ Gough, GR Bantug, FI Hamid, FK Nally, CP Duffy, AL Gorman, AM Liddicoat, EC Lavelle, C Hess, PJ Oefner, DK Finlay, GP Davey, T Robson, AM Curtis, PJ Hertzog, BRG Williams, CE McCoy
Nature Communications, 2021-03-05;12(1):1460.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Small Immunomodulatory Molecules as Potential Therapeutics in Experimental Murine Models of Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS)
Authors: D Shah, P Das, S Acharya, B Agarwal, DJ Christense, SM Robertson, V Bhandari
International Journal of Molecular Sciences, 2021-03-04;22(5):.
Species: Mouse
Sample Types: BALF
-
Fish Oil Enriched in EPA, but Not in DHA, Reverses the Metabolic Syndrome and Adipocyte Dysfunction Induced by a High-Fat Diet
Authors: RDC da Cunha d, JJ Simão, VSD Silva, TM Farias, MM Cruz, VJ Antraco, L Armelin-Co, MI Alonso-Val
Nutrients, 2021-02-26;13(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sevoflurane preconditioning activates HGF/Met-mediated autophagy to attenuate hepatic ischemia-reperfusion injury in mice
Authors: X Xiao, D Liu, S Chen, X Li, M Ge, W Huang
Cellular Signalling, 2021-02-25;0(0):109966.
Species: Mouse
Sample Types: Tissue Homogenates
-
Gene expression patterns associated with Leishmania panamensis infection in macrophages from BALB/c and C57BL/6 mice
Authors: CM Restrepo, A Llanes, L Herrera, E Ellis, R Lleonart, PL Fernández
PloS Neglected Tropical Diseases, 2021-02-22;15(2):e0009225.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NLRP6-associated host microbiota composition impacts in the intestinal barrier to systemic dissemination of Brucella abortus
Authors: M Rungue, V Melo, D Martins, PC Campos, G Leles, I Galvão, V Mendes, M Aganetti, Á Pedersen, NRG Assis, R Santos, GD Cassali, ALB Godard, FS Martins, SC Oliveira, AT Vieira
PloS Neglected Tropical Diseases, 2021-02-22;15(2):e0009171.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cardiolipin-mediated PPAR&gamma S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia
Authors: M Garg, S Johri, S Sagar, A Mundhada, A Agrawal, P Ray, K Chakrabort
Cell Reports, 2021-02-09;34(6):108736.
Species: Mouse
Sample Types: Tissue Homogenates
-
Gymnema inodorum (Lour.) Decne. Extract Alleviates Oxidative Stress and Inflammatory Mediators Produced by RAW264.7 Macrophages
Authors: B Dunkhuntho, C Talabnin, M Murphy, K Thumanu, P Sittisart, G Eumkeb
Oxidative Medicine and Cellular Longevity, 2021-02-04;2021(0):8658314.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protein Digests and Pure Peptides from Chia Seed Prevented Adipogenesis and Inflammation by Inhibiting PPAR&gamma and NF-&kappaB Pathways in 3T3L-1 Adipocytes
Authors: M Grancieri, HSD Martino, E Gonzalez d
Nutrients, 2021-01-08;13(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Olive Leaf Extract, from Olea europaea L., Reduces Palmitate-Induced Inflammation via Regulation of Murine Macrophages Polarization
Authors: P De Cicco, M Maisto, GC Tenore, A Ianaro
Nutrients, 2020-11-28;12(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inducing regulated necrosis and shifting macrophage polarization with anti-EMMPRIN antibody (161-pAb) and complement factors
Authors: N Hijaze, M Ledersnaid, E Simanovich, S Kassem, MA Rahat
J Leukoc Biol, 2020-11-17;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease
Authors: DM de Graaf, RJA Maas, SP Smeekens, E Eisenmesse, JS Redzic, MM Helsen, NE Powers, S Li, V Kalabokis, MS Gresnigt, LAB Joosten, CA Dinarello, FL van de Vee
Cytokine, 2020-10-28;137(0):155334.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neuroinflammaging underlies emotional disturbances and circadian rhythm disruption in young male senescence-accelerated mouse prone 8 mice
Authors: N Ito, H Takemoto, A Hasegawa, C Sugiyama, K Honma, T Nagai, Y Kobayashi, H Odaguchi
Exp Gerontol, 2020-10-16;0(0):111109.
Species: Mouse
Sample Types: Serum
-
Combination of Innate Immune Modulators as Vaccine Adjuvants in Mice
Authors: A Haddadi, A Chaffey, SH Ng, D Yalamati, HL Wilson
Vaccines (Basel), 2020-10-01;8(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-&beta1 up-regulate miR-132 and promote mouse M2 macrophage polarization
Authors: Y Wang, B Han, Y Wang, C Wang, H Zhang, J Xue, X Wang, T Niu, Z Niu, Y Chen
J. Cell. Mol. Med., 2020-09-23;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Th17/Treg imbalance in COPD development: suppressors of cytokine signaling and signal transducers and activators of transcription proteins
Authors: LEF Silva, JD Lourenço, KR Silva, FPR Santana, JB Kohler, AR Moreira, APP Velosa, CM Prado, RP Vieira, MV Aun, IFLC Tibério, JT Ito, FDTQS Lopes
Scientific Reports, 2020-09-17;10(1):15287.
Species: Mouse
Sample Types: Tissue Homogenates
-
Activation of the NLRP3 Inflammasome by Particles from the Echinococcus granulosus Laminated Layer
Authors: C Casaravill, Á Pittini, D Rückerl, JE Allen, Á Díaz
Infect. Immun., 2020-08-19;88(9):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Antileishmanial activity of a new chloroquine analog in an animal model of Leishmania panamensis infection
Authors: L Herrera, A Llanes, J Álvarez, K Degracia, CM Restrepo, R Rivera, DE Stephens, HT Dang, OV Larionov, R Lleonart, PL Fernández
Int J Parasitol Drugs Drug Resist, 2020-08-15;14(0):56-61.
Species: Mouse
Sample Types: Cell Culture Supernates
-
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1&beta expression
Authors: JJ Balic, H Albargy, K Luu, FJ Kirby, WSN Jayasekara, F Mansell, DJ Garama, D De Nardo, N Baschuk, C Louis, F Humphries, K Fitzgerald, E Latz, DJ Gough, A Mansell
Nat Commun, 2020-07-30;11(1):3816.
Species: Mouse
Sample Types: Cell Lysates
-
Immunomodulatory Effect of a Salvia plebeia R. Aqueous Extract in Forced Swimming Exercise-induced Mice
Authors: J Shin, OK Kim, S Kim, D Bae, J Lee, J Park, W Jun
Nutrients, 2020-07-28;12(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection
Authors: CE Heim, ME Bosch, KJ Yamada, AL Aldrich, SS Chaudhari, D Klinkebiel, CM Gries, AA Alqarzaee, Y Li, VC Thomas, E Seto, AR Karpf, T Kielian
Nat Microbiol, 2020-07-13;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TLR2 and endosomal TLR-mediated secretion of IL-10 and immune suppression in response to phagosome-confined Listeria monocytogenes
Authors: BN Nguyen, A Chávez-Arr, MI Cheng, M Krasilniko, A Louie, DA Portnoy
PLoS Pathog., 2020-07-07;16(7):e1008622.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-7/alphaIL-7 mAb M25 immunocomplexes expand CD8+ T cells but paradoxically abrogate the antitumor activity of CTLA-4 and PD-1 blockage
Authors: D Hrabos, T Hnizdilova, J Tomala, J Uhlik, M Kovar
Cytokine, 2020-06-26;133(0):155174.
Species: Mouse
Sample Types: Serum
-
Antitumor and Anti-Metastatic Effects of Citral-Loaded Nanostructured Lipid Carrier in 4T1-Induced Breast Cancer Mouse Model
Authors: N Nordin, SK Yeap, HS Rahman, NR Zamberi, NE Mohamad, N Abu, MJ Masarudin, R Abdullah, NB Alitheen
Molecules, 2020-06-09;25(11):.
Species: Mouse
Sample Types: Serum
-
Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis
Authors: H Liu, X Yang, K Tang, T Ye, C Duan, P Lv, L Yan, X Wu, Z Chen, J Liu, Y Deng, G Zeng, J Xing, Z Ye, H Xu
Theranostics, 2020-06-05;10(16):7319-7334.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Strain-Specific Differences in House Dust Mite (Dermatophagoides farinae)-Induced Mouse Models of Allergic Rhinitis
Authors: KI Lee, JS Bae, EH Kim, JH Kim, L Lyu, YJ Chung, JH Mo
Clin Exp Otorhinolaryngol, 2020-05-15;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages
Authors: YR Na, JW Kwon, DY Kim, H Chung, J Song, D Jung, H Quan, D Kim, JS Kim, YW Ju, W Han, HS Ryu, YS Lee, JJ Hong, SH Seok
Cell Rep, 2020-05-12;31(6):107643.
Species: Mouse
Sample Types:
-
The Role of ST2 Receptor in the Regulation of Brucella abortus Oral Infection
Authors: R Santos, PC Campos, M Rungue, V Rocha, D Santos, V Mendes, FV Marinho, F Martins, MF Ricci, DCD Reis, GD Cassali, JC Alves-Filh, AT Vieira, SC Oliveira
Pathogens, 2020-04-28;9(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Brucella ovis mutant in ABC transporter protects against Brucella canis infection in mice and it is safe for dogs
Authors: C Eckstein, JPS Mol, FB Costa, PP Nunes, PA Lima, MM Melo, TP Carvalho, DO Santos, MF Silva, TF Carvalho, LF Costa, OAO Melo Júnio, RC Giunchette, TA Paixão, RL Santos
PLoS ONE, 2020-04-16;15(4):e0231893.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model
Authors: AP Bonfanti, N Barreto, J Munhoz, M Caballero, G Cordeiro, T Rocha-E-Si, R Sutti, F Moura, S Brunetto, CD Ramos, R Thomé, L Verinaud, C Rapôso
Sci Rep, 2020-04-03;10(1):5876.
Species: Mouse
Sample Types: Cell Cultue Supernates
-
Combination therapy using human papillomavirus L1/E6/E7 genes and archaeosome: a nanovaccine confer immuneadjuvanting effects to fight cervical cancer
Authors: H Karimi, H Soleimanja, A Abdoli, RS Banijamali
Sci Rep, 2020-04-01;10(1):5787.
Species: Mouse
Sample Types: Cell Culture Superantes
-
The Exopolysaccharide of Lactobacillus fermentum UCO-979C Is Partially Involved in Its Immunomodulatory Effect and Its Ability to Improve the Resistance against Helicobacter pylori Infection
Authors: V Garcia-Cas, G Marcial, L Albarracín, M Tomokiyo, P Clua, H Takahashi, H Kitazawa, A Garcia-Can, J Villena
Microorganisms, 2020-03-27;8(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-&kappaB pathway
Authors: G Wan, Y An, J Tao, Y Wang, Q Zhou, R Yang, Q Liang
Biosci. Rep., 2020-03-27;40(3):.
Species: Mouse
Sample Types: Serum
-
M1 Polarization but Anti-LPS-Induced Inflammation and Anti-MCF-7 Breast Cancer Cell Growth Effects of Five Selected Polysaccharides
Authors: HC Lin, JY Lin
Evid Based Complement Alternat Med, 2020-03-25;2020(0):9450246.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance
Authors: KJ Yamada, CE Heim, X Xi, KS Attri, D Wang, W Zhang, PK Singh, TK Bronich, T Kielian
PLoS Pathog., 2020-03-06;16(3):e1008354.
Species: Mouse
Sample Types: Cell Culture Supernates
-
HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation
Authors: XAMH van Dieren, MA de la Rosa, A Georgiadi, F Mattijssen, W Dijk, M van Weeghe, R Singh, JW Borst, R Stienstra, S Kersten
Cell Rep, 2020-02-11;30(6):1811-1822.e6.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A live auxotrophic vaccine confers mucosal immunity and protection against lethal pneumonia caused by virulent Pseudomonas aeruginosa
Authors: MP Cabral, A Correia, M Vilanova, F Gärtner, M Moscoso, P García, JA Vallejo, A Pérez, M Francisco-, V Fuentes-Va, G Bou
PLoS Pathog., 2020-02-10;16(2):e1008311.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fish oil reverses metabolic syndrome, adipocyte dysfunction, and altered adipokines secretion triggered by high-fat diet-induced obesity
Authors: RDC da Cunha d, MM Cruz, TM de Farias, VS da Silva, J de Jesus S, MM Telles, MIC Alonso-Val
Physiol Rep, 2020-02-01;8(4):e14380.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance
Authors: XAMH van Dieren, T Sancerni, MC Alves-Guer, R Stienstra
J Biol Chem, 2020-01-01;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunomodulatory effect of Syphacia obvelata in treatment of experimental DSS-induced colitis in mouse model
Authors: N Taghipour, N Mosaffa, HA Aghdaei, M Rostami-Ne, JV Weinstock, S Shahnavaz, MR Zali
Sci Rep, 2019-12-13;9(1):19127.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Strongyloides venezuelensis-infection alters the profile of cytokines and liver inflammation in mice co-infected with Schistosoma mansoni
Authors: MC de Rezende, JMP Moreira, LLM Fernandes, VF Rodrigues, D Negrão-Cor
Cytokine, 2019-11-26;127(0):154931.
Species: Mouse
Sample Types: Tissue Homogenates
-
SOCS2 modulates adipose tissue inflammation and expansion in mice
Authors: CH Val, MC de Oliveir, DR Lacerda, A Barroso, NV Batista, Z Menezes-Ga, DRR de Assis, AT Cramer, F Brant, MM Teixeira, D Glória Sou, AM Ferreira, FS Machado
J. Nutr. Biochem., 2019-11-23;76(0):108304.
Species: Mouse
Sample Types: Tissue Homogenates
-
A novel mouse model for septic arthritis induced by Pseudomonas aeruginosa
Authors: T Jin, M Mohammad, Z Hu, Y Fei, ERB Moore, R Pullerits, A Ali
Sci Rep, 2019-11-14;9(1):16868.
Species: Mouse
Sample Types: Serum
-
Enzyme Treatment Alters the Anti-Inflammatory Activity of the Water Extract of Wheat Germ In Vitro and In Vivo
Authors: Y Song, HY Jeong, JK Lee, YS Choi, DO Kim, D Jang, CS Park, S Maeng, H Kang
Nutrients, 2019-10-16;11(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Decreased viability and neurite length in neural cells treated with chitosan-dextran sulfate nanocomplexes
Authors: LN Zamproni, D Teixeira, A Arnaut All, I Longo Maug, A des Rieux, MA Porcionatt
Neurotoxicology, 2019-10-09;76(0):33-43.
Species: Mouse
Sample Types: Tissue Homogenates
-
Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation
Authors: JD Bailey, M Diotallevi, T Nicol, E McNeill, A Shaw, S Chuaiphich, A Hale, A Starr, M Nandi, E Stylianou, H McShane, S Davis, R Fischer, BM Kessler, J McCullagh, KM Channon, MJ Crabtree
Cell Rep, 2019-07-02;28(1):218-230.e7.
Species: Mouse, Transgenic Mouse
Sample Types: Cell Culture Supernates
-
Concomitant Infection of S.�mansoni and H.�pylori Promotes Promiscuity of Antigen-Experienced Cells and Primes the Liver for a Lower Fibrotic Response
Authors: S Bhattachar, R Mejías-Luq, E Loffredo-V, A Toska, M Flossdorf, M Gerhard, C Prazeres d
Cell Rep, 2019-07-02;28(1):231-244.e5.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Oral administration of EPA-rich oil impairs collagen reorganization due to elevated production of IL-10 during skin wound healing in mice
Authors: B Burger, CMC Kühl, T Candreva, RDS Cardoso, JR Silva, BG Castelucci, SR Consonni, HL Fisk, PC Calder, MAR Vinolo, HG Rodrigues
Sci Rep, 2019-06-24;9(1):9119.
Species: Mouse
Sample Types: Tissue Homogenates
-
Role of adipose tissue inflammation in fat pad loss induced by fasting in lean and mildly obese mice
Authors: DR Lacerda, KA Costa, ALM Silveira, DF Rodrigues, AN Silva, JL Sabino, V Pinho, GB Menezes, DD Soares, MM Teixeira, AVM Ferreira
J. Nutr. Biochem., 2019-06-21;72(0):108208.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
Authors: AL Frisbee, MM Saleh, MK Young, JL Leslie, ME Simpson, MM Abhyankar, CA Cowardin, JZ Ma, P Pramoonjag, SD Turner, AP Liou, EL Buonomo, WA Petri
Nat Commun, 2019-06-20;10(1):2712.
Species: Mouse
Sample Types: Tissue Homogenates
-
Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosis Infection via STING-Dependent Type 2 Immunity
Authors: S Benmerzoug, B Bounab, S Rose, D Gosset, F Biet, T Cochard, A Xavier, N Rouxel, L Fauconnier, WGC Horsnell, B Ryffel, D Togbe, VFJ Quesniaux
Cell Rep, 2019-05-28;27(9):2649-2664.e5.
Species: Mouse
Sample Types: Tissue Homogenates
-
In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy
Authors: VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza
EBioMedicine, 2019-05-23;0(0):.
Species: Mouse
Sample Types: Plasma
-
The immunoreceptor CD300a controls the intensity of inflammation and dysfunction in a model of Ag-induced arthritis in mice
Authors: BVS Valiate, RU Alvarez, L Karra, CM Queiroz-Jú, FA Amaral, F Levi-Schaf, MM Teixeira
J. Leukoc. Biol., 2019-05-20;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
Stem Cells, 2019-05-13;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism
Authors: JL Fachi, JS Felipe, LP Pral, BK da Silva, RO Corrêa, MCP de Andrade, DM da Fonseca, PJ Basso, NOS Câmara, ÉL de Sales E, F Dos Santos, SES Guima, AM Thomas, JC Setubal, YT Magalhães, FL Forti, T Candreva, HG Rodrigues, MB de Jesus, SR Consonni, ADS Farias, P Varga-Weis, MAR Vinolo
Cell Rep, 2019-04-16;27(3):750-761.e7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice
Authors: TA Diniz, JCJ Aquino Jún, FC Mosele, C Cabral-San, EA Lima Junio, AAS Teixeira, FS Lira, JC Rosa Neto
Cytokine, 2019-03-20;119(0):71-80.
Species: Mouse
Sample Types: Tissue Homogenates
-
The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages
Authors: OM Finucane, J Sugrue, A Rubio-Arai, MV Guillot-Se, MA Lynch
Sci Rep, 2019-03-11;9(1):4034.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Murine astrocytes produce IL-24 and are susceptible to the immunosuppressive effects of this cytokine
Authors: AR Burmeister, MB Johnson, JJ Yaemmongko, I Marriott
J Neuroinflammation, 2019-03-02;16(1):55.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials
Authors: F Zahedifard, H Lee, JH No, M Salimi, N Seyed, A Asoodeh, S Rafati
PLoS Negl Trop Dis, 2019-02-27;13(2):e0007217.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice
Authors: A Recino, SU Gan, KC Sia, Y Sawyer, J Trendell, R Kay, FM Gribble, F Reimann, R Foale, M Notaridou, N Holmes, A Lever, KO Lee, A Nathwani, A Cooke, R Calne, M Wallberg
Gene Ther., 2018-12-04;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Basophils are dispensable for the establishment of protective adaptive immunity against primary and challenge infection with the intestinal helminth parasite Strongyloides ratti
Authors: M Reitz, ML Brunn, D Voehringer, M Breloer
PLoS Negl Trop Dis, 2018-11-29;12(11):e0006992.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer
Authors: MH Kubala, V Punj, VR Placencio-, H Fang, GE Fernandez, R Sposto, YA DeClerck
Cell Rep, 2018-11-20;25(8):2177-2191.e7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Omega-9 Oleic Acid, the Main Compound of Olive Oil, Mitigates Inflammation during Experimental Sepsis
Authors: IM Medeiros-d, CF Gonçalves-, ARM Kurz, FMJ Oliveira, VHP de Abreu, RC Torres, VF Carvalho, V Estato, PT Bozza, M Sperandio, HC de Castro-, AR Silva
Oxid Med Cell Longev, 2018-11-13;2018(0):6053492.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Analysis of the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties
Authors: LP Leroux, M Nasr, R Valanparam, M Tam, BA Rosa, E Siciliani, DE Hill, DS Zarlenga, M Jaramillo, JV Weinstock, TG Geary, MM Stevenson, JF Urban, M Mitreva, A Jardim
Sci Rep, 2018-10-29;8(1):15921.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Preconditioning of bone marrow-derived mesenchymal stem cells highly strengthens their potential to promote IL-6-dependent M2b polarization
Authors: D Philipp, L Suhr, T Wahlers, YH Choi, A Paunel-Gör
Stem Cell Res Ther, 2018-10-25;9(1):286.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Insufficient IL-10 Production as a Mechanism Underlying the Pathogenesis of Systemic Juvenile Idiopathic Arthritis
Authors: M Imbrechts, A Avau, J Vandenhaut, B Malengier-, K Put, T Mitera, N Berghmans, O Burton, S Junius, A Liston, L de Somer, C Wouters, P Matthys
J. Immunol., 2018-09-28;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Vaccination with whole-cell killed or recombinant leishmanial protein and toll-like receptor agonists against Leishmania tropica in BALB/c mice
Authors: M Rostamian, F Bahrami, HM Niknam
PLoS ONE, 2018-09-24;13(9):e0204491.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IGF-1-Overexpressing Mesenchymal Stem/Stromal Cells Promote Immunomodulatory and Proregenerative Effects in Chronic Experimental Chagas Disease
Authors: DN Silva, BSF Souza, CM Azevedo, JF Vasconcelo, PG de Jesus, MS Feitoza, CS Meira, GB Carvalho, BR Cavalcante, R Ribeiro-Do, MBP Soares
Stem Cells Int, 2018-07-24;2018(0):9108681.
Species: Mouse
Sample Types: Serum
-
Choline transport links macrophage phospholipid metabolism and inflammation
Authors: SA Snider, KD Margison, P Ghorbani, ND LeBlond, C O'Dwyer, JR Nunes, T Nguyen, H Xu, SA Bennett, MD Fullerton
J. Biol. Chem., 2018-06-07;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD71+ Erythroid Suppressor Cells Promote Fetomaternal Tolerance through Arginase-2 and PDL-1
Authors: C Delyea, N Bozorgmehr, P Koleva, G Dunsmore, S Shahbaz, V Huang, S Elahi
J. Immunol., 2018-05-07;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Activation of M1 macrophages play a critical role in the initiation of acute lung injury
Authors: HL Lu, XY Huang, YF Luo, WP Tan, PF Chen, YB Guo
Biosci. Rep., 2018-04-27;0(0):.
Species: Mouse
Sample Types: Serum
-
Canonical PI3K? signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis
Authors: MC Silva, M Davoli-Fer, TS Medina, R Sesti-Cost, GK Silva, CD Lopes, LE Cardozo, FN Gava, K Lyroni, FC Dias, AF Frade, M Baron, HI Nakaya, F Figueiredo, JC Alves-Filh, FQ Cunha, C Tsatsanis, C Chevillard, E Cunha-Neto, E Hirsch, JS Silva, TM Cunha
Nat Commun, 2018-04-17;9(1):1513.
Species: Mouse
Sample Types: Serum
-
Filamin A Is Required for Optimal T Cell Integrin-Mediated Force Transmission, Flow Adhesion, and T Cell Trafficking
Authors: T Savinko, C Guenther, LM Uotila, M Llort Asen, S Yao, S Tojkander, SC Fagerholm
J. Immunol., 2018-03-26;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Identification of periplakin as a major regulator of lung injury and repair in mice
Authors: V Besnard, R Dagher, T Madjer, A Joannes, M Jaillet, M Kolb, P Bonniaud, LA Murray, MA Sleeman, B Crestani
JCI Insight, 2018-03-08;3(5):.
Species: Mouse
Sample Types: BALF
-
Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice
Authors: MJ Park, SH Lee, EK Kim, EJ Lee, JA Baek, SH Park, SK Kwok, ML Cho
Sci Rep, 2018-02-28;8(1):3753.
Species: Mouse
Sample Types: Cell Culture Supernates
-
An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
Authors: RG Carroll, Z Zas?ona, S Galván-Peñ, EL Koppe, DC Sévin, S Angiari, M Triantafil, K Triantafil, LK Modis, LA O'Neill
J. Biol. Chem., 2018-02-20;293(15):5509-5521.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A Novel Role for C5a in B-1 Cell Homeostasis
Authors: K Bröker, J Figge, AF Magnusen, RA Manz, J Köhl, CM Karsten
Front Immunol, 2018-02-19;9(0):258.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation
Authors: JC d'Avila, LD Siqueira, A Mazeraud, EP Azevedo, D Foguel, HC Castro-Far, T Sharshar, F Chrétien, FA Bozza
J Neuroinflammation, 2018-01-30;15(1):28.
Species: Mouse
Sample Types: Tissue Homogenates
-
Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
Authors: L Boutens, GJ Hooiveld, S Dhingra, RA Cramer, MG Netea, R Stienstra
Diabetologia, 2018-01-14;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia
Authors: S Paetau, T Rolova, L Ning, CG Gahmberg
Front Mol Neurosci, 2017-12-22;10(0):431.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Paradoxical role of tumor necrosis factor on metabolic dysfunction and adipose tissue expansion in mice
Authors: LB Martins, MC Oliveira, Z Menezes-Ga, DF Rodrigues, JP Lana, LQ Vieira, MM Teixeira, AVM Ferreira
Nutrition, 2017-07-17;50(0):1-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner
Authors: M Coorens, VAF Schneider, AM de Groot, A van Dijk, M Meijerink, JM Wells, MR Scheenstra, EJA Veldhuizen, HP Haagsman
J. Immunol., 2017-07-14;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis
Authors: A Imai, K Satoi, E Fujimoto, K Sato
Heliyon, 2017-06-22;3(6):e00327.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Elevated prostaglandin E2 post-bone marrow transplant mediates interleukin-1?-related lung injury
Authors: GJ Martínez-C, QM Taylor, CA Wilke, AB Podsiad, BB Moore
Mucosal Immunol, 2017-06-07;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice
Authors: TB Oriss, M Raundhal, C Morse, RE Huff, S Das, R Hannum, MC Gauthier, KL Scholl, K Chakrabort, SM Nouraie, SE Wenzel, P Ray, A Ray
JCI Insight, 2017-05-18;2(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Somatic extracts of Marshallagia marshalli downregulate the Th2 associated immune responses in ovalbumin-induced airway inflammation in BALB/c mice
Authors: S Parande Sh, A Ebrahimby, A Dousty, M Maleki, A Movassaghi, H Borji, A Haghparast
Parasit Vectors, 2017-05-12;10(1):233.
Species: Mouse
Sample Types: BALF
-
Contributions of CD8 T cells to the pathogenesis of mouse adenovirus type 1 respiratory infection
Authors: CT Molloy, JS Andonian, HM Seltzer, MC Procario, ME Watson, JB Weinberg
Virology, 2017-04-11;507(0):64-74.
Species: Mouse
Sample Types: BALF
-
Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells
Authors: C Li, I Maillet, C Mackowiak, C Viala, F Di Padova, M Li, D Togbe, V Quesniaux, Y Lai, B Ryffel
Cell Death Dis, 2017-04-06;8(4):e2735.
Species: Mouse
Sample Types: Tissue Homogenates
-
NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury
Authors: JP Barrett, RJ Henry, S Villapol, BA Stoica, A Kumar, MP Burns, AI Faden, DJ Loane
J Neuroinflammation, 2017-03-24;14(1):65.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response
Authors: M Lynch, TA Walsh, I Marszalows, AE Webb, M MacAogain, TR Rogers, H Windle, D Kelleher, MJ O'Connell, CE Loscher
BMC Evol. Biol, 2017-03-23;17(1):90.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Obesity-induced diet leads to weight gain, systemic metabolic alterations, adipose tissue inflammation, hepatic steatosis, and oxidative stress in gerbils (Meriones unguiculatus)
Authors: LL Ventura, NC Fortes, HC Santiago, MV Caliari, MA Gomes, DR Oliveira
PeerJ, 2017-03-02;5(0):e2967.
Species: Gerbil
Sample Types: Tissue Homogenates
-
Toll-Like Receptor 2 Is Required for Inflammatory Process Development during Leishmania infantum Infection
Authors: LA Sacramento, JL da Costa, MH de Lima, PA Sampaio, RP Almeida, FQ Cunha, JS Silva, V Carregaro
Front Microbiol, 2017-02-23;8(0):262.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interspecies cathelicidin comparison reveals divergence in antimicrobial activity, TLR modulation, chemokine induction and regulation of phagocytosis
Authors: M Coorens, MR Scheenstra, EJ Veldhuizen, HP Haagsman
Sci Rep, 2017-01-19;7(0):40874.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Suppression of colitis by adoptive transfer of helminth antigen-treated dendritic cells requires interleukin-4 receptor-� signaling
Authors: CE Matisz, B Faz-L¢pez, E Thomson, A Al Rajabi, F Lopes, LI Terrazas, A Wang, KA Sharkey, DM McKay
Sci Rep, 2017-01-17;7(0):40631.
Species: Mouse
Sample Types: Cell Culture Supernates
-
B-cell subsets are modulated during allergic airway inflammation but are not required for the development of respiratory tolerance in a murine model
Eur. J. Immunol, 2017-01-17;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia
Authors: K Chakrabort, M Raundhal, BB Chen, C Morse, YY Tyurina, A Khare, TB Oriss, R Huff, JS Lee, CM St Croix, S Watkins, RK Mallampall, VE Kagan, A Ray, P Ray
Nat Commun, 2017-01-11;8(0):13944.
Species: Mouse
Sample Types: Tissue Homogenates
-
Antiinflammatory actions of inorganic nitrate stabilize the atherosclerotic plaque
Authors: RS Khambata, SM Ghosh, KS Rathod, T Thevathasa, F Filomena, Q Xiao, A Ahluwalia
Proc. Natl. Acad. Sci. U.S.A, 2017-01-05;0(0):.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy
Nat Commun, 2016-12-22;7(0):13894.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dysfunction of hepatic regulatory T cells in experimental sclerosing cholangitis is related with IL-12 signaling
Authors: Dorothee Schwinge
J. Hepatol, 2016-12-10;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lectins from Synadenium carinatum (ScLL) and Artocarpus heterophyllus (ArtinM) Are Able to Induce Beneficial Immunomodulatory Effects in a Murine Model for Treatment of Toxoplasma gondii Infection
Authors: EL Ramos, SS Santana, MV Silva, FM Santiago, TW Mineo, JR Mineo
Front Cell Infect Microbiol, 2016-11-25;6(0):164.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Comparison of potential protection conferred by three immunization strategies (protein/protein, DNA/DNA, and DNA/protein) against Brucella infection using Omp2b in BALB/c Mice
Authors: Saeid Bouzari
Vet. Microbiol., 2016-11-05;197(0):47-52.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Evaluating the effects of refined carbohydrate and fat diets with acute ethanol consumption using a mouse model of alcoholic liver injury
Authors: Ana Lúcia Brunialti-
J. Nutr. Biochem., 2016-09-22;39(0):93-100.
Species: Mouse
Sample Types: Tissue Homogenates
-
Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2?
J Biol Chem, 2016-09-20;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
Infect Immun, 2016-09-19;0(0):.
Species: Mouse
Sample Types: Serum
-
Proinflammatory M1 macrophages inhibit RANKL-induced osteoclastogenesis
Infect Immun, 2016-09-19;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Testosterone-Mediated Endocrine Function and TH1/TH2 Cytokine Balance after Prenatal Exposure to Perfluorooctane Sulfonate: By Sex Status
Int J Mol Sci, 2016-09-12;17(9):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Alternatively Activated Mononuclear Phagocytes from the Skin Site of Infection and the Impact of IL-4R? Signalling on CD4+T Cell Survival in Draining Lymph Nodes after Repeated Exposure to Schistosoma mansoni Cercariae
PLoS Negl Trop Dis, 2016-08-09;10(8):e0004911.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The circadian clock regulates inflammatory arthritis
FASEB J, 2016-08-03;0(0):.
Species: Mouse
Sample Types: Serum
-
Cannabinoid receptor 2 modulates susceptibility to experimental cerebral malaria through a CCL17-dependent mechanism
J Biol Chem, 2016-07-29;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interleukin-27 Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response
Authors: Gustavo F S Quirino
Infect Immun, 2016-07-21;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
ER? in CD4+ T Cells Is Crucial for Ligand-Mediated Suppression of Central Nervous System Autoimmunity
J Immunol, 2016-05-13;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis
PLoS ONE, 2016-05-09;11(5):e0154630.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immune Cell-Conditioned Media Suppress Prostate Cancer PC-3 Cell Growth Correlating With Decreased Proinflammatory/Anti-inflammatory Cytokine Ratios in the Media Using 5 Selected Crude Polysaccharides
Integr Cancer Ther, 2016-04-29;15(4):NP13-NP25.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Impact of Histone H1 on the Progression of Allergic Rhinitis and Its Suppression by Neutralizing Antibody in Mice
Authors: T Nakano, R Kamei, T Fujimura, Y Takaoka, A Hori, CY Lai, KC Chiang, Y Shimada, N Ohmori, T Goto, K Ono, CL Chen, S Goto, S Kawamoto
PLoS ONE, 2016-04-18;11(4):e0153630.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-22 Restrains Tapeworm-Mediated Protection against Experimental Colitis via Regulation of IL-25 Expression
Authors: JL Reyes, MR Fernando, F Lopes, G Leung, NL Mancini, CE Matisz, A Wang, DM McKay
PLoS Pathog, 2016-04-07;12(4):e1005481.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Jucara pulp supplementation improves glucose tolerance in mice.
Authors: Oyama L, Silva F, Carnier J, de Miranda D, Santamarina A, Ribeiro E, Oller do Nascimento C, de Rosso V
Diabetol Metab Syndr, 2016-01-22;8(0):8.
Species: Mouse
Sample Types: Tissue Homogenates
-
Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury.
Authors: Avila L, Bruggemann T, Bobinski F, da Silva M, Oliveira R, Martins D, Mazzardo-Martins L, Duarte M, de Souza L, Dafre A, Vieira R, Santos A, Bonorino K, Hizume Kunzler D
PLoS ONE, 2015-09-02;10(9):e0137273.
Species: Mouse
Sample Types: Tissue Homogenates
-
In vivo imaging and tracking of host-microbiota interactions via metabolic labeling of gut anaerobic bacteria.
Authors: Geva-Zatorsky N, Alvarez D, Hudak J, Reading N, Erturk-Hasdemir D, Dasgupta S, von Andrian U, Kasper D
Nat Med, 2015-08-17;21(9):1091-100.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding.
Authors: Jovicic N, Jeftic I, Jovanovic I, Radosavljevic G, Arsenijevic N, Lukic M, Pejnovic N
PLoS ONE, 2015-07-28;10(7):e0134089.
Species: Mouse
Sample Types: Tissue Homogenates
-
Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-beta Production.
Authors: Niedzielska M, Raffi F, Tel J, Muench S, Jozefowski K, Alati N, Lahl K, Mages J, Billmeier U, Schiemann M, Appelt U, Wirtz S, Sparwasser T, Hochrein H, Figdor C, Keyse S, Lang R
J Immunol, 2015-07-13;195(4):1753-62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism.
Authors: Sanin D, Prendergast C, Mountford A
J Immunol, 2015-06-26;195(3):1218-32.
Species: Mouse
Sample Types: Cell Culture Supernates
-
De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes.
Authors: Alissafi T, Hatzioannou A, Ioannou M, Sparwasser T, Grun J, Grutzkau A, Verginis P
J Immunol, 2015-05-06;194(12):5812-24.
-
Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells.
Authors: Khan A, Amu S, Saunders S, Hams E, Blackshields G, Leonard M, Weaver C, Sparwasser T, Sheils O, Fallon P
Eur J Immunol, 2015-04-14;45(6):1842-54.
Species: Mouse
Sample Types: Serum
-
Modulation of recombinant antigenic constructs containing multi-epitopes towards effective reduction of atherosclerotic lesion in B6;129S-Ldlr(tm1Her)Apob(tm2Sgy)/J mice.
Authors: Xia M, Chen D, Endresz V, Lantos I, Szabo A, Kakkar V, Lu X
PLoS ONE, 2015-04-01;10(4):e0123393.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Critical role of IL-33 receptor ST2 in experimental cerebral malaria development.
Authors: Palomo J, Reverchon F, Piotet J, Besnard A, Couturier-Maillard A, Maillet I, Tefit M, Erard F, Mazier D, Ryffel B, Quesniaux V
Eur J Immunol, 2015-03-20;45(5):1354-65.
Species: Mouse
Sample Types: Tissue Homogenates
-
Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin.
Authors: Pfarr K, Danciu C, Arlt O, Neske C, Dehelean C, Pfeilschifter J, Radeke H
PLoS ONE, 2015-03-10;10(3):e0118802.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Deltex1 antagonizes HIF-1alpha and sustains the stability of regulatory T cells in vivo.
Authors: Hsiao H, Hsu T, Liu W, Hsieh W, Chou T, Wu Y, Jiang S, Lai M
Nat Commun, 2015-02-19;6(0):6353.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Consistent inhibition of cyclooxygenase drives macrophages towards the inflammatory phenotype.
Authors: Na Y, Yoon Y, Son D, Jung D, Gu G, Seok S
PLoS ONE, 2015-02-13;10(2):e0118203.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis.
Authors: Bernard N, Finlay C, Tannahill G, Cassidy J, O'Neill L, Mills K
Mucosal Immunol, 2014-12-17;8(5):982-92.
Species: Mouse
Sample Types: Tissue Homogenates
-
Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection.
Authors: Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J
Mucosal Immunol, 2014-12-10;8(4):896-905.
Species: Mouse
Sample Types: Tissue Homogenates
-
Protection against Streptococcus pneumoniae lung infection after nasopharyngeal colonization requires both humoral and cellular immune responses.
Authors: Wilson R, Cohen J, Jose R, de Vogel C, Baxendale H, Brown J
Mucosal Immunol, 2014-10-29;8(3):627-39.
Species: Mouse
Sample Types: Tissue Homogenates
-
MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity.
Authors: Salama A, Fichou N, Allard M, Dubreil L, De Beaurepaire L, Viel A, Jegou D, Bosch S, Bach J
PLoS ONE, 2014-09-09;9(9):e106153.
Species: Mouse
Sample Types: Cell Culture Supernates
-
No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.
Authors: Mancuso P, O Brien E, Prano J, Goel D, Aronoff D
PLoS ONE, 2014-09-09;9(9):e106420.
Species: Mouse
Sample Types: BALF
-
Metabolic profile response to administration of epigallocatechin-3-gallate in high-fat-fed mice.
Authors: Moreno M, De Laquila R, Okuda M, Lira F, de Souza G, de Souza C, Telles M, Ribeiro E, do Nascimento C, Oyama L
Diabetol Metab Syndr, 2014-08-12;6(1):84.
Species: Mouse
Sample Types: Tissue Homogenates
-
TLR9 ligands induce S100A8 in macrophages via a STAT3-dependent pathway which requires IL-10 and PGE2.
Authors: Hsu, Kenneth, Chung, Yuen Min, Endoh, Yasumi, Geczy, Carolyn
PLoS ONE, 2014-08-06;9(8):e103629.
Species: Mouse
Sample Types: Cell Culture Supernates
-
LPS induces the degradation of programmed cell death protein 4 (PDCD4) to release Twist2, activating c-Maf transcription to promote interleukin-10 production.
Authors: van den Bosch M, Palsson-Mcdermott E, Johnson D, O'Neill L
J Biol Chem, 2014-06-30;289(33):22980-90.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections.
Authors: Redlich S, Ribes S, Schutze S, Nau R
J Neuroinflammation, 2014-06-14;11(0):108.
Species: Mouse
Sample Types: Tissue Homogenates
-
The glycosylated Rv1860 protein of mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG.
Authors: Satchidanandam V, Kumar N, Jumani R, Challu V, Elangovan S, Khan N
PLoS Pathog, 2014-06-12;10(6):e1004176.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures.
Authors: Pritchard A, Mir A, Dev K
PLoS ONE, 2014-06-09;9(6):e99444.
Species: Mouse
Sample Types: Cell Culture Supernates
-
miR-27a regulates inflammatory response of macrophages by targeting IL-10.
Authors: Xie N, Cui H, Banerjee S, Tan Z, Salomao R, Fu M, Abraham E, Thannickal V, Liu G
J Immunol, 2014-05-16;193(1):327-34.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection.
Authors: Brant F, Miranda A, Esper L, Rodrigues D, Kangussu L, Bonaventura D, Soriani F, Pinho V, Souza D, Rachid M, Weiss L, Tanowitz H, Teixeira M, Teixeira A, Machado F
Infect Immun, 2014-05-12;82(8):3127-40.
Species: Mouse
Sample Types: Tissue Homogenates
-
Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
Authors: Assi H, Espinosa J, Suprise S, Sofroniew M, Doherty R, Zamler D, Lowenstein P, Castro M
PLoS ONE, 2014-05-07;9(5):e96318.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1.
Authors: Heinemann C, Heink S, Petermann F, Vasanthakumar A, Rothhammer V, Doorduijn E, Mitsdoerffer M, Sie C, Prazeres da Costa O, Buch T, Hemmer B, Oukka M, Kallies A, Korn T
Nat Commun, 2014-05-06;5(0):3770.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Pulmonary immune responses to 2009 pandemic influenza A (H1N1) virus in mice.
Authors: Lv J, Wang D, Hua Y, Pei S, Wang J, Hu W, Wang X, Jia N, Jiang Q
BMC Infect Dis, 2014-04-12;14(0):197.
Species: Mouse
Sample Types: Tissue Homogenates
-
Sm10.3, a member of the micro-exon gene 4 (MEG-4) family, induces erythrocyte agglutination in vitro and partially protects vaccinated mice against Schistosoma mansoni infection.
Authors: Martins V, Morais S, Pinheiro C, Assis N, Figueiredo B, Ricci N, Alves-Silva J, Caliari M, Oliveira S
PLoS Negl Trop Dis, 2014-03-20;8(3):e2750.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential IL-10 production by DCs determines the distinct adjuvant effects of LPS and PTX in EAE induction.
Authors: Zhou H, Wang Y, Lian Q, Yang B, Ma Y, Wu X, Sun S, Liu Y, Sun B
Eur J Immunol, 2014-03-07;44(5):1352-62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
An iron-acquisition-deficient mutant of Corynebacterium pseudotuberculosis efficiently protects mice against challenge.
Authors: Ribeiro D, Rocha F, Leite K, Soares S, Silva A, Portela R, Meyer R, Miyoshi A, Oliveira S, Azevedo V, Dorella F
Vet Res, 2014-03-06;45(0):28.
Species: Mouse
Sample Types: Cell Culture Supernates
-
miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease.
Authors: Feng J, Li A, Deng J, Yang Y, Dang L, Ye Y, Li Y, Zhang W
Lipids Health Dis, 2014-02-07;13(0):27.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12-interferon-gamma pathway.
Authors: Badr M, Qinna N, Qadan F, Matalka K
Onco Targets Ther, 2014-02-07;7(0):193-201.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Foxp3(+) regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice.
Authors: Blankenhaus B, Reitz M, Brenz Y, Eschbach M, Hartmann W, Haben I, Sparwasser T, Huehn J, Kuhl A, Feyerabend T, Rodewald H, Breloer M
PLoS Pathog, 2014-02-06;10(2):e1003913.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Acerola (Malpighia emarginata DC.) juice intake protects against alterations to proteins involved in inflammatory and lipolysis pathways in the adipose tissue of obese mice fed a cafeteria diet.
Authors: Dias F, Leffa D, Daumann F, Marques S, Luciano T, Possato J, de Santana A, Neves R, Rosa J, Oyama L, Rodrigues B, de Andrade V, de Souza C, de Lira F
Lipids Health Dis, 2014-02-04;13(0):24.
Species: Mouse
Sample Types: Tissue Homogenates
-
MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity.
Authors: Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, Milan E, Orfanelli U, Fazzalari N, Campana L, Capobianco A, Otten L, Particelli F, Acha-Orbea H, Baruffaldi F, Faccio R, Sitia R, Reith W, Cenci S
J Bone Miner Res, 2014-02-01;29(2):290-303.
Species: Mouse
Sample Types: Cell Culture Supernates
-
PPAR-gamma/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis.
Authors: Ferreira A, Sisti F, Sonego F, Wang S, Filgueiras L, Brandt S, Serezani A, Du H, Cunha F, Alves-Filho J, Serezani C
J Immunol, 2014-01-31;192(5):2357-65.
Species: Mouse
Sample Types: Serum
-
Protective or deleterious role of scavenger receptors SR-A and CD36 on host resistance to Staphylococcus aureus depends on the site of infection.
Authors: Blanchet C, Jouvion G, Fitting C, Cavaillon J, Adib-Conquy M
PLoS ONE, 2014-01-31;9(1):e87927.
Species: Mouse
Sample Types: BALF
-
Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1?-dependent inflammation.
Authors: Tynan, Graham A, Hearnden, Claire H, Oleszycka, Ewa, Lyons, Claire L, Coutts, Graham, O'Connell, Jean, Corrigan, Michelle, Lynch, Lydia, Campbell, Matthew, Callanan, John J, Mok, Kenneth, Geoghegan, Justin, O'Farrelly, Cliona, Allan, Stuart M, Roche, Helen M, O'Shea, Donal B, Lavelle, Ed C
Diabetes, 2014-01-23;63(6):2037-50.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion.
Authors: Menezes-Garcia Z, Oliveira M, Lima R, Soriani F, Cisalpino D, Botion L, Teixeira M, Souza D, Ferreira A
Obesity (Silver Spring), 2013-12-14;22(3):663-72.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bifidobacterium longum alleviates dextran sulfate sodium-induced colitis by suppressing IL-17A response: involvement of intestinal epithelial costimulatory molecules.
Authors: Miyauchi, Eiji, Ogita, Tasuku, Miyamoto, Junki, Kawamoto, Seiji, Morita, Hidetosh, Ohno, Hiroshi, Suzuki, Takuya, Tanabe, Soichi
PLoS ONE, 2013-11-08;8(11):e79735.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation.
Authors: Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G
Diabetes, 2013-11-05;63(3):850-66.
Species: Mouse
Sample Types: Plasma
-
Mesenchymal stem cells inhibit cutaneous radiation-induced fibrosis by suppressing chronic inflammation.
Authors: Horton J, Hudak K, Chung E, White A, Scroggins B, Burkeen J, Citrin D
Stem Cells, 2013-10-01;31(10):2231-41.
Species: Mouse
Sample Types: Tissue Homogenates
-
A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
Authors: Fevre C, Almeida A, Taront S, Pedron T, Huerre M, Prevost M, Kieusseian A, Cumano A, Brisse S, Sansonetti P, Tournebize R
EMBO Mol Med, 2013-04-01;5(4):516-30.
Species: Mouse
Sample Types: Tissue Homogenates
-
Continuous and discontinuous cigarette smoke exposure differentially affects protective Th1 immunity against pulmonary tuberculosis.
Authors: Shaler C, Horvath C, McCormick S, Jeyanathan M, Khera A, Zganiacz A, Kasinska J, Stampfli M, Xing Z
PLoS ONE, 2013-03-19;8(3):e59185.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TLR2 deletion promotes arthritis through reduction of IL-10.
Authors: Huang Q, Koessler R, Birkett R, Perlman H, Xing L, Pope R
J Leukoc Biol, 2013-02-27;93(5):751-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Genetic deletion of the HIF-1alpha isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model.
Authors: Georgiev P, Belikoff B, Hatfield S, Ohta A, Sitkovsky M, Lukashev D
Eur J Immunol, 2013-01-31;43(3):655-66.
Species: Mouse
Sample Types: Serum
-
UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.
Authors: Schamber-Reis B, Petritus P, Caetano B, Martinez E, Okuda K, Golenbock D, Scott P, Gazzinelli R
J Biol Chem, 2013-01-16;288(10):7127-36.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of OGR1 in myeloid-derived cells in prostate cancer.
Authors: Yan, L, Singh, L S, Zhang, L, Xu, Y
Oncogene, 2012-12-10;33(2):157-64.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Depletion of phagocytic myeloid cells triggers spontaneous T cell- and NK cell-dependent antitumor activity.
Authors: Guth A, Hafeman S, Dow S
Oncoimmunology, 2012-11-01;1(8):1248-1257.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immune Modulation Mediated by Cryptococcal Laccase Promotes Pulmonary Growth and Brain Dissemination of Virulent Cryptococcus neoformans in Mice.
Authors: Qiu Y, Davis M, Dayrit J, Hadd Z, Meister D, Osterholzer J, Williamson P, Olszewski M
PLoS ONE, 2012-10-22;7(10):e47853.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Control of allergen-induced inflammation and hyperresponsiveness by the metalloproteinase ADAMTS-12.
Authors: Paulissen G, El Hour M, Rocks N, Gueders M, Bureau F, Foidart J, Lopez-Otin C, Noel A, Cataldo D
J Immunol, 2012-09-07;189(8):4135-43.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-10 mediated regulation of liver inflammation during acute murine cytomegalovirus infection.
Authors: Gaddi, Pamela J, Crane, Meredith, Kamanaka, Masahito, Flavell, Richard, Yap, George S, Salazar-Mather, Thais P
PLoS ONE, 2012-08-03;7(8):e42850.
Species: Mouse
Sample Types: Serum
-
Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.
J. Immunol., 2012-07-11;189(4):1911-9.
Species: Mouse
Sample Types: Serum
-
Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration.
Authors: Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I
Eur. J. Immunol., 2012-05-01;42(5):1226-36.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TLR9 and MyD88 are crucial for the development of protective immunity to malaria.
Authors: Gowda NM, Wu X, Gowda DC
J. Immunol., 2012-04-18;188(10):5073-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via alphavbeta1 integrin.
Authors: Kang S, Okuno T, Takegahara N, Takamatsu H, Nojima S, Kimura T, Yoshida Y, Ito D, Ohmae S, You DJ, Toyofuku T, Jang MH, Kumanogoh A
J. Immunol., 2011-12-23;188(3):1108-16.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2011-10-24;80(1):100-9.
Species: Mouse
Sample Types: Serum
-
The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
Authors: El-Behi M, Ciric B, Dai H
Nat. Immunol., 2011-04-24;12(6):568-75.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
J. Immunol., 2011-03-25;186(9):5425-34.
Species: Mouse
Sample Types: Tissue Homogenates
-
Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice.
Authors: Nel HJ, Hams E, Saunders SP
J. Immunol., 2011-03-11;186(8):4631-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mal mediates TLR-induced activation of CREB and expression of IL-10.
Authors: Mellett M, Atzei P, Jackson R, O'Neill LA, Moynagh PN
J. Immunol., 2011-03-11;186(8):4925-35.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Natural IgM is required for suppression of inflammatory arthritis by apoptotic cells.
Authors: Notley CA, Brown MA, Wright GP, Ehrenstein MR
J. Immunol., 2011-03-07;186(8):4967-72.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
Authors: Barber DL, Mayer-Barber KD, Feng CG
J. Immunol., 2010-12-20;186(3):1598-607.
Species: Mouse
Sample Types: BALF
-
Phosphoinositide 3-kinase gamma plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.
Authors: Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffe E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM
J. Leukoc. Biol., 2010-11-02;89(2):269-82.
Species: Mouse
Sample Types: Tissue Homogenates
-
A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
Authors: Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P, Gerard NP, Gerard C, Wills-Karp M, Kohl J
J. Immunol., 2010-10-25;185(11):6741-52.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mucosal delivery of human papillomavirus pseudovirus-encapsidated plasmids improves the potency of DNA vaccination.
Authors: Graham BS, Kines RC, Corbett KS, Nicewonger J, Roberts JN, Schiller JT, Buck CB
Mucosal Immunol, 2010-06-16;3(5):475-86.
Species: Mouse
Sample Types: BALF
-
A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4.
Authors: Reynolds CM, Draper E, Keogh B, Rahman A, Moloney AP, Mills KH, Loscher CE, Roche HM
J. Nutr., 2009-10-21;139(12):2351-7.
Species: Mouse
Sample Types: Cell Culture Supernates
-
E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
J. Immunol., 2009-07-27;183(4):2642-9.
Species: Mouse
Sample Types: BALF
-
Mucosal immunity in mice induced by orally administered transgenic rice.
Authors: Zhang X, Yuan Z, Duan Q, Zhu H, Yu H, Wang Q
Vaccine, 2009-01-13;27(10):1596-600.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.
Authors: Han Y, Guo Q, Zhang M, Chen Z, Cao X
J. Immunol., 2009-01-01;182(1):111-20.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
Circulation, 2008-10-27;118(20):2063-72.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IFN-gamma synergizes with LPS to induce nitric oxide biosynthesis through glycogen synthase kinase-3-inhibited IL-10.
Authors: Lin CF, Tsai CC, Huang WC, Wang CY, Tseng HC, Wang Y, Kai JI, Wang SW, Cheng YL
J. Cell. Biochem., 2008-10-15;105(3):746-55.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mutual modulation between interleukin-10 and interleukin-6 induced by Rhodococcus aurantiacus infection in mice.
Authors: Yimin, Kohanawa M, Ozaki M, Haga S, Fujikawa K, Zhao S, Kuge Y, Tamaki N
Microbes Infect., 2008-09-13;10(14):1450-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation.
Authors: Lages CS, Suffia I, Velilla PA, Huang B, Warshaw G, Hildeman DA, Belkaid Y, Chougnet C
J. Immunol., 2008-08-01;181(3):1835-48.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function.
Authors: Csoka B, Himer L, Selmeczy Z, Vizi ES, Pacher P, Ledent C, Deitch EA, Spolarics Z, Nemeth ZH, Hasko G
FASEB J., 2008-07-14;22(10):3491-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
Authors: Miyazaki Y, Shimanoe Y, Wang S, Yoshida H
Biochem. Biophys. Res. Commun., 2008-06-20;373(3):397-402.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Direct B cell stimulation by dendritic cells in a mouse model of lupus.
Authors: Wan S, Zhou Z, Duan B, Morel L
Arthritis Rheum., 2008-06-01;8(0):1741-50.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infection.
Authors: Schaefer M, Reiling N, Fessler C, Stephani J, Taniuchi I, Hatam F, Yildirim AO, Fehrenbach H, Walter K, Ruland J, Wagner H, Ehlers S, Sparwasser T
J. Immunol., 2008-05-15;180(10):6836-45.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.
Authors: Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME
Proc. Natl. Acad. Sci. U.S.A., 2008-05-14;105(20):7240-5.
Species: Mouse
Sample Types: BALF
-
Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
J. Immunol., 2008-03-15;180(6):4022-31.
Species: Mouse
Sample Types: Tissue Homogenates
-
The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation.
Authors: Matalka KZ, Ali D, Khawad AE, Qa'dan F
Cytokine, 2007-11-26;40(3):235-40.
Species: Mouse
Sample Types: Serum
-
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells.
Authors: Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CJ, Gran B, Ciric B, Rostami A
Nat. Immunol., 2007-11-11;8(12):1372-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.
Authors: Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J
Neurobiol. Dis., 2007-10-16;29(2):336-53.
Species: Mouse
Sample Types: Plasma
-
Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: a critical factor in controlling experimental autoimmune encephalomyelitis.
Authors: Ephrem A, Chamat S, Miquel C, Fisson S, Mouthon L, Caligiuri G, Delignat S, Elluru S, Bayry J, Lacroix-Desmazes S, Cohen JL, Salomon BL, Kazatchkine MD, Kaveri SV, Misra N
Blood, 2007-10-11;111(2):715-22.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production.
Authors: Wang KX, Shi Y, Denhardt DT
Proc. Natl. Acad. Sci. U.S.A., 2007-09-04;104(37):14777-82.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
Authors: Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK
Vaccine, 2007-07-27;25(37):6730-43.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism.
Authors: Levy BD, Lukacs NW, Berlin AA, Schmidt B, Guilford WJ, Serhan CN, Parkinson JF
FASEB J., 2007-07-11;21(14):3877-84.
Species: Mouse
Sample Types: Tissue Homogenates
-
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007-04-12;26(4):445-59.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.
Authors: Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, Ishii H, Nakayama S, Yanagihara K, Mizuta Y, Kohno S
Clin. Exp. Immunol., 2007-03-01;147(3):540-6.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dietary fish oil increases the number of splenic macrophages secreting TNF-alpha and IL-10 but decreases the secretion of these cytokines by splenic T cells from mice.
Authors: Petursdottir DH, Hardardottir I
J. Nutr., 2007-03-01;137(3):665-70.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Glucose-6-phosphate dehydrogenase deficiency and the inflammatory response to endotoxin and polymicrobial sepsis.
Authors: Wilmanski J, Villanueva E, Deitch EA, Spolarics Z
Crit. Care Med., 2007-02-01;35(2):510-8.
Species: Mouse
Sample Types: Plasma
-
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
J. Immunol., 2006-12-01;177(11):7980-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-tumor necrosis factor alpha F(ab')2 antibody fragments protect in murine polymicrobial sepsis: concentration and early intervention are fundamental to the outcome.
Authors: Marquez-Velasco R, Bojalil R, Buelna A, Flores-Guzman F, Estevez-Ramirez J, Laguna J, Hernandez AM, Diaz-Quinonez A, Paniagua-Solis JF
Inflamm. Res., 2006-09-01;55(9):378-84.
Species: Mouse
Sample Types: Serum
-
Effects of dexamethasone on macrophage migration inhibitory factor production in sepsis.
Authors: Bruhn A, Verdant C, Vercruysse V, Su F, Vray B, Vincent JL
Shock, 2006-08-01;26(2):169-73.
Species: Mouse
Sample Types: Plasma
-
Exogenous IL-12 suppresses experimental autoimmune encephalomyelitis (EAE) by tuning IL-10 and IL-5 levels in an IFN-gamma-dependent way.
Authors: Berghmans N, Dillen C, Heremans H
J. Neuroimmunol., 2006-06-09;176(1):63-75.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunity induced with a Salmonella enterica serovar Enteritidis live vaccine is regulated by Th1-cell-dependent cellular and humoral effector mechanisms in susceptible BALB/c mice.
Authors: Lehmann J, Springer S, Werner CE, Lindner T, Bellmann S, Straubinger RK, Selbitz HJ, Alber G
Vaccine, 2006-03-29;24(22):4779-93.
Species: Mouse
Sample Types: Serum
-
Hierarchical suppression of asthma-like responses by mucosal tolerance.
Authors: Keller AC, Mucida D, Gomes E, Faquim-Mauro E, Faria AM, Rodriguez D, Russo M
J. Allergy Clin. Immunol., 2006-02-01;117(2):283-90.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.
Authors: Powell JM, Sonnenfeld G
J. Interferon Cytokine Res., 2006-01-01;26(1):34-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis.
Authors: Carpenter KJ, Hogaboam CM
Infect. Immun., 2005-11-01;73(11):7198-207.
Species: Mouse
Sample Types: Tissue Homogenates
-
Anti-inflammatory activity in the aqueous crude extract of the leaves of Nidularium procerum: A bromeliaceae from the Brazilian coastal rain forest.
Authors: Amendoeira FC, Frutuoso VS, Zanon C, Chedier LM, Figueiredo MR, Kaplan MA, Bandeira-Melo C, Bozza PT, Castro-Faria-Neto HC
Biol. Pharm. Bull., 2005-06-01;28(6):1010-5.
Species: Mouse
Sample Types: Pleural Fluid
-
Attenuation of primary nonfunction for syngeneic islet graft using sodium 4-phenylbutyrate.
Authors: Fu SH, Chen ST, Hsu BR
Transplant. Proc., 2005-05-01;37(4):1830-1.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Leukemia inhibitory factor is linked to regulatory transplantation tolerance.
Authors: Metcalfe SM, Watson TJ, Shurey S, Adams E, Green CJ
Transplantation, 2005-03-27;79(6):726-30.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Leukaemia inhibitory factor (LIF) is functionally linked to axotrophin and both LIF and axotrophin are linked to regulatory immune tolerance.
Authors: Metcalfe SM, Muthukumarana PA, Thompson HL, Haendel MA, Lyons GE
FEBS Lett., 2005-01-31;579(3):609-14.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The IgE adjuvant effect of particles: characterisation of the primary cellular response in the draining lymph node.
Authors: Nygaard UC, Ormstad H, Aase A, Lovik M
Toxicology, 2005-01-15;206(2):181-93.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions.
Authors: Aviles H, Belay T, Vance M, Sun B, Sonnenfeld G
J. Appl. Physiol., 2004-06-11;97(4):1437-44.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cytokine production in association with phagocytosis of apoptotic cells by immature dendritic cells.
Authors: Takahashi M, Kobayashi Y
Cell. Immunol., 2003-12-01;226(2):105-15.
Species: Mouse
Sample Types: Cell Culture Supernates
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Kit works good but not very good at detecting IL-10 in M2 macrophages
very simple and steady
RAW Cell conditioned medium following stimulation with 10ng/mL LPS for 24 hours
Result has been published in 10.1371/journal.pone.0058258