Home / PDGF R alpha / Mouse PDGF R alpha Antibody

Mouse PDGF R alpha Antibody

Catalog #: AF1062
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AF1062
AF1062-SP
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Detection of Mouse PDGF R alpha by Western Blot.
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Mouse PDGF R alpha Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse PDGF R alpha in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) PDGF R alpha, rhPDGF R beta, and recombinant mouse PDGF R beta is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse PDGF R alpha
Leu25-Glu524 (Asp65Glu, Gly439Ala, Thr440Ala)
Accession # P26618
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
See below
Flow Cytometry
0.25 µg/106 cells
3T3-L1 mouse embryonic fibroblast adipose-like cell line
Immunohistochemistry
5-15 µg/mL
See below
Neutralization
Measured by its ability to neutralize PDGF‑AA-induced proliferation in the NR6R‑3T3 mouse fibroblast cell line. The Neutralization Dose (ND50) is typically 0.2 - 1.6 µg/mL in the presence of 250 ng/mL Recombinant Human PDGF‑AA.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Mouse PDGF Ra antibody by Western Blot. View Larger

Detection of Mouse PDGF R alpha by Western Blot. Western blot shows lysates of mouse uterus tissue and mouse lung tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Mouse PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). Specific bands were detected for PDGF Ra at approximately 160-200 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Immunohistochemistry PDGF Ra antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

PDGF R alpha in Mouse Embryo. PDGF Ra was detected in immersion fixed frozen sections of mouse embryo using Goat Anti-Mouse PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Immunohistochemistry PDGF Ra antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

PDGF R alpha in Mouse Embryo. PDGF Ra was detected in immersion fixed frozen sections of mouse embryo using 15 µg/mL Goat Anti-Mouse PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; CTS008) and counterstained with hematoxylin (blue). Specific labeling was localized to the plasma membrane of mesenchymal cells. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Neutralization Cell Proliferation Induced by PDGF‑AA and Neutralization by Mouse PDGF R alpha Antibody. View Larger

Cell Proliferation Induced by PDGF‑AA and Neutralization by Mouse PDGF R alpha Antibody. Recombinant Human PDGF-AA (221-AA) stimulates proliferation in the NR6R-3T3 mouse fibroblast cell line in a dose-dependent manner (orange line), as measured by Resazurin (AR002. Proliferation elicited by Recombinant Human PDGF-AA (250 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062). The ND50 is typically 0.2-1.6 µg/mL.

Immunocytochemistry/ Immunofluorescence Detection of Rat PDGF R alpha by Immunocytochemistry/Immunofluorescence. View Larger

Detection of Rat PDGF R alpha by Immunocytochemistry/Immunofluorescence. Extracellularly applied recombinant human alpha -syn PFFs induced cytoplasmic alpha -syn-immunoreactive inclusions in primary BCAS1(+) cell cultures. Immunostaining of oligodendroglial cells incubated with 1 μM alpha -syn PFFs for 24 h from days 3 (upper) and 4 (lower) after differentiation induction showing the ubiquitous development of thioflavin S-labeled inclusions in PDGFR alpha (+) cells and BCAS1(+) cells. In contrast, few BCAS1(−)/MBP(+) cells developed thioflavin S-labeled inclusions. Scale bar = 50 μm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32727582), licensed under a CC-BY licence.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. View Larger

Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. Rspo3 mRNAs are localized on telopodes that extend away from the cell bodies of the mouse VTTs. VTTs are marked by Lgr5 mRNA (red dots), Rspo3 mRNA (green dots) is localized away from the cell body, PDGFRa antibody mark VTTs cell bodies and telopodes. Scale bar–10 µm, in inset, green arrows point to Rspo3 mRNAs (green dots) localized on PDGFRa telopodes (blue). Telocyte cell body is marked by white dashed line. inset Scale bar–5 µm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32321913), licensed under a CC-BY licence.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. View Larger

Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. Leptin promotes OPC proliferation. Representative image of cultured OPCs stained with antibodies against LepRb (green) and PDGFR alpha (red). Scale bar: 25 μm. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep40397), licensed under a CC-BY licence.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. View Larger

Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. LPC injection does not enhance leptin expression in the CNS. Representative images of LepRb (green) expression in combination with PDGFR alpha, GFAP NeuN, and CD11b (red) in the mouse spinal cord with or without LPC injection. Spinal cord sections were obtained 3 days after LPC injection. Graph indicates the relative intensity of leptin protein expression in indicated cell type (n = 3). P = 0.287452 (PDGFR alpha ), 0.181059 (GFAP), 0.199972 (NeuN), Student’s t-test, n.s. indicates no significant difference. *P < 0.05, **P < 0.01, error bars represent SEM. Scale bar: 25 μm. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep40397), licensed under a CC-BY licence.

Immunohistochemistry Detection of Mouse PDGF R alpha by Immunohistochemistry. View Larger

Detection of Mouse PDGF R alpha by Immunohistochemistry. PDGFR alpha driven mouse brain tumor model. Example of early stage tumor growth, as revealed by IHC for proliferation marker Ki67 and PDGFR alpha. Note high density of Ki67+ proliferating cells in tumor area, increased expression level of PDGFR alpha, and invasive migration of tumor cells through corpus callosum into contralateral hemisphere. Scale bar: 50 μm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25683249), licensed under a CC-BY licence.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. View Larger

Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. OPC expresses leptin receptors. Representative images of mouse spinal cord sections, which were double-labeled for LepRb (green) in combination with PDGFR alpha (red). Spinal cord sections were obtained 7 days after LPC injection; the graph shows quantification (n = 3). P = 0.007573 (LepRb flox vs intact CKO), 0.0108779 (LepRb flox vs LPC CKO), ANOVA with Tukey’s post-hoc test. Scale bar: 25 μm. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep40397), licensed under a CC-BY licence.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. View Larger

Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. Endogenous leptin sustains spontaneous OPC proliferation. Representative images of mouse spinal cord sections, which were prepared 7 days (left panels) and 14 days (right panels) after LPC injection and double labeled for BrdU in combination with PDGFR alpha (upper panels), GSTπ (upper panels) and olig2 (lower panels). BrdU was administrated during 3–7 days after LPC injection; the graph shows quantification (n = 5–8). P = 0.042915 (PDGFR alpha and BrdU labeled cells), 0.013560 (Olig2 and BrdU labeled cells 7 days after injection), 0.012111 (GSTπ and BrdU labeled cells), 0.009797 (Olig2 and BrdU labeled cells 14 days after injection), Student’s t-test. Scale bar: 50 μm. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep40397), licensed under a CC-BY licence.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. View Larger

Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. Etv5 is necessary and sufficient for proliferation and cell fate bias downstream of Cic loss. Cic-null mouse NSCs (CicnullEmpty), Cic-null mouse NSCs with dominant negative Etv5 (CicnullDN-Etv5), and Cic-wildtype mouse NSCs overexpressing Etv5 (Etv5 overpression) were grown in lineage-directed culture conditions and assessed for their ability to differentiate to oligodendrocytes as determined by immunostaining for Olig2, Pdgfra, and Mbp. Scale bar: 10 μm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31043608), licensed under a CC-BY licence.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. View Larger

Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. Transplantation of CD11b/LIF transgenic BMCs reduces the numbers of FAPs in dystrophic muscle but does not affect phenotype. To quantify the number of FAPs, transgenic mouse muscle sections were co-labeled with antibodies to PDGFR alpha (red) and CD31, CD45 (green). Arrowheads indicate FAPs (CD31-CD45-PDGFR alpha +). Bar = 50 μm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31243277), licensed under a CC-BY licence.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. View Larger

Detection of Mouse PDGF R alpha by Immunocytochemistry/Immunofluorescence. Lgr5 is expressed abundantly in mouse villus tip telocytes. d) Lgr5 mRNA (red dots) expressed in PDGFRa+ VTTs that co-express Bmp4 mRNA (green dots). Scale bar–10 µm. Red arrows point to Lgr5 and Bmp4 double positive cells. e) Blow up of the region boxed in d). Scale bar–5 µm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32321913), licensed under a CC-BY licence.

Immunohistochemistry Detection of Mouse PDGFR alpha by Immunohistochemistry View Larger

Detection of Mouse PDGFR alpha by Immunohistochemistry PDGFR alpha driven brain tumors display features of high grade glioma.(a–g) Histopathological analysis of tumor areas by H&E staining shows a high concentration of mitotic figures (a, arrows), high cellularity and nuclear atypia (b), perineuronal satellitosis (c; N, neuronal nuclei), perivascular growth (d), intrafascicular growth (e), subarachnoid spreading (f), and areas of incipient necrosis (g; arrows point to pyknotic nuclei). (h–k) IF labeling of brain tumor sections for cell type specific markers. Nuclei labeled with DAPI are shown in blue. Tumor cells with high PDGFR alpha expression were highly proliferative, as seen by proliferation marker Ki67 (h), and express the OPC cell lineage markers Olig2, Sox2, Sox10, and Ng2, as well as the neural stem cell marker Nestin (i–k). Tumor cells were negative for immunosignal of astroglial marker GFAP, mature oligodendrocyte marker APC-CC1, and neuronal marker NeuN (l–n). Scale bars: 10 μm (a–g), 20 μm (h–n). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25683249), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse PDGFR alpha by Immunohistochemistry View Larger

Detection of Mouse PDGFR alpha by Immunohistochemistry PDGFR alpha driven brain tumors display features of high grade glioma.(a–g) Histopathological analysis of tumor areas by H&E staining shows a high concentration of mitotic figures (a, arrows), high cellularity and nuclear atypia (b), perineuronal satellitosis (c; N, neuronal nuclei), perivascular growth (d), intrafascicular growth (e), subarachnoid spreading (f), and areas of incipient necrosis (g; arrows point to pyknotic nuclei). (h–k) IF labeling of brain tumor sections for cell type specific markers. Nuclei labeled with DAPI are shown in blue. Tumor cells with high PDGFR alpha expression were highly proliferative, as seen by proliferation marker Ki67 (h), and express the OPC cell lineage markers Olig2, Sox2, Sox10, and Ng2, as well as the neural stem cell marker Nestin (i–k). Tumor cells were negative for immunosignal of astroglial marker GFAP, mature oligodendrocyte marker APC-CC1, and neuronal marker NeuN (l–n). Scale bars: 10 μm (a–g), 20 μm (h–n). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25683249), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse PDGFR alpha by Immunohistochemistry View Larger

Detection of Mouse PDGFR alpha by Immunohistochemistry PDGFR alpha driven brain tumor model.(a) Schematic diagram of PDGFR alpha J/K knock-in alleles. ATG, start codon; SA, splice acceptor; STOP, PGK-neo cassette. (b) Kaplan-Meier survival curves of 4 mouse mutant cohorts with brain tumors. Mice generally succumbed to subcutaneous fibrosarcomas, and brain tumors were detected by histological analysis. (c) Example of early stage tumor growth, as revealed by IHC for proliferation marker Ki67 and PDGFR alpha. Note high density of Ki67+ proliferating cells in tumor area, increased expression level of PDGFR alpha, and invasive migration of tumor cells through corpus callosum into contralateral hemisphere. (d) H&E staining of an advanced brain tumor growth (asterisk in tumor centre, dashed line demarcates expansion). Scale bars: 50 μm (c, d). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25683249), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence Etv5 is necessary and sufficient for proliferation and cell fate bias downstream of Cic loss. a–f Cic-null NSCs (CicnullEmpty), Cic-null NSCs with dominant negative Etv5 (CicnullDN-Etv5), and Cic-wildtype NSCs overexpressing Etv5 (Etv5 overpression) were grown in lineage-directed culture conditions and assessed for their ability to differentiate to neurons, astrocytes, and oligodendrocytes as determined by immunostaining for bIII-Tubulin (Tuj1), Gfap, and Olig2, Pdgfra, and Mbp. Scale bar: 10 μm. Analysis of Tuj1 + cells from NSCs in neuronal differentiating condition, NDC a, d; analysis of Gfap + cells from NSCs in astrocytic differentiating condition, ADC b, e; and analyses of Olig2 + , Pdgfra + , and Mbp + cells from NSCs in oligodendrocyte differentiating condition, ODC c, f from n = 3 biological replicates, with three technical replicates each, for cell culture studies. g, h Representative images and quantitation of EdU incorporation 2 days post electroporation of wildtype ETV5 or empty control plasmid, both carrying mCherry as a marker, into E13 CICFl/Fl VZ. Note: mCherry fluorescence and EdU staining were false-colorized to green and red after grayscale imaging. Scale bar: 50 μm. Data from n = 4 mice per each group. Scale bar: 50 μm. i, j Representative images and quantitation of EdU incorporation 2 days post-electroporation of Cre only or of Cre co-electroporated with DNETV5 into E13 CICFl/Fl VZ. Data from n = 4 mice per each group. Scale bar: 50 μm k EdU incorporation assay in cultured Cic-wildtype NSCs without or with ETV5 overexpression from n ≥ 3 biological replicates. l EdU incorporation in Cic-floxed NSCs with Cre, and without or with DNETV5 expression from n ≥ 3 biological replicates. Data shown as mean ± SD. Statistical analyses performed either t test in h, j, k, l; or with ANOVA with Tukey’s post hoc test in d, e, f. ns–not significant, *p < 0.05, **p < 0.01, ***p < 0.0001. Source data are provided as a Source Data file. ADC–astrocytic differentiation condition, NDC–neuronal differentiation condition, ODC–oligodendrocytic differentiation condition. VZ–ventricular zone, LV–lateral ventricle Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31043608), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence LPC injection does not enhance leptin expression in the CNS.(a) Representative images of MBP expression in a mouse spinal cord 14 days after LPC injection are shown; the graph shows quantification of the demyelinating area in the dorsal spinal cord (n = 3–4). P = 0.001542, Student’s t-test. (b) Representative images of NeuN expression in a mouse spinal cord 14 days after LPC injection; the graph shows quantification of the density of NeuN-positive cells in the spinal cord (n = 3). P = 0.299940, Student’s t-test, n.s. indicates no significant difference. (c) Quantification of leptin protein expression in indicated organs. Tissues were obtained from the mice 3 days after LPC injection (n = 3 for control, 4 for LPC injection). P = 0.318966 (adipose tissue), 0.10446 (brain stem), 0.332281 (cerebellum), 0.345245 (liver), 0.453104 (kidney), 0.098135 (heart), 0.335722 (lung), 0.236771 (muscle), 0.44662 (spleen), 0.465966 (stomach). Student’s t-test. n.s. indicates no significant difference. (d) Quantification of spinal cord leptin protein 3 days after LPC injection (n = 3 for control, 4 for LPC injection). P = 0.026865, Student’s t-test. (e) Quantification of spinal cord leptin mRNA 3 days after LPC injection (n = 6). P = 0.324930, Student’s t-test, n.s. indicates no significant difference. (f) Representative images of LepRb (green) expression in combination with PDGFR alpha, GFAP NeuN, and CD11b (red) in the mouse spinal cord with or without LPC injection. Spinal cord sections were obtained 3 days after LPC injection. Graph indicates the relative intensity of leptin protein expression in indicated cell type (n = 3). P = 0.287452 (PDGFR alpha ), 0.181059 (GFAP), 0.199972 (NeuN), Student’s t-test, n.s. indicates no significant difference. *P < 0.05, **P < 0.01, error bars represent SEM. Scale bars; 100 μm for (a and b), 25 μm for (f). Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep40397), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence Leptin promotes OPC proliferation.(a) Representative image of cultured OPCs stained with antibodies against LepRb (green) and PDGFR alpha (red). Scale bar: 25 μm. (b) Relative BrdU incorporation into the OPC obtained from the brain (left graph) and spinal cord (right graph). Cells were treated with recombinant leptin for 48 h (n = 4). (Left graph) P = 0.005993 (control vs 10 ng/mL), 0.045616 (control vs 100 ng/mL), (Right graph) P = 0.004456 (control vs 10 ng/mL), 0.017859 (control vs 100 ng/mL). (c) Relative BrdU incorporation into the OPC after leptin stimulation (10 ng/ml) with U0126 (20 μM), a MEK inhibitor (n = 4 for brain OPCs, n = 3 for spinal cord OPCs). (Left graph) P = 0.019753 (control vs leptin), 0.039433 (leptin vs leptin + U0126), (Right graph) P = 0.045545 (control vs leptin), 0.04486 (leptin vs leptin + U0126). (d) Representative images of western blotting (upper panels) and quantitative analysis of ERK phosphorylation (lower graph) are shown. OPCs were treated with leptin (10 ng/ml) under indicated periods (n = 3). P = 0.006352 (2 min), 0.016571 (5 min), 0.017675 (10 min), 0.024100 (15 min), 0.081342 (30 min). *P < 0.05, **P < 0.01, ANOVA with Tukey’s post-hoc test. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep40397), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Rat PDGFR alpha by Immunocytochemistry/Immunofluorescence View Larger

Detection of Rat PDGFR alpha by Immunocytochemistry/Immunofluorescence Extracellularly applied recombinant human alpha -syn PFFs induced cytoplasmic alpha -syn-immunoreactive inclusions in primary BCAS1(+) cell cultures. a Confocal images of BCAS1(+) cells, which were incubated with 1 μM alpha -syn PFFs for 24 h from day 4 after differentiation induction, showing the intracellular inclusions labeled with both anti-alpha -syn antibody and thioflavin S. Scale bar = 5 μm. b Immunostaining of oligodendroglial cells incubated with 1 μM alpha -syn PFFs for 24 h from days 3 (upper) and 4 (lower) after differentiation induction showing the ubiquitous development of thioflavin S-labeled inclusions in PDGFR alpha (+) cells and BCAS1(+) cells. In contrast, few BCAS1(−)/MBP(+) cells developed thioflavin S-labeled inclusions. Scale bar = 50 μm. c The percentages of oligodendroglial cells containing thioflavin S-labeled inclusions were compared between BCAS1(−)/PDGFR alpha (+) cells and BCAS1(+)/PDGFR alpha (+) cells (upper, performed on day 3), and between BCAS1(+)/MBP(+) cells and BCAS1(−)/MBP(+) cells (lower, performed on day 4). N = 4, respectively, independent culture, Mann–Whitney, p* < 0.05 Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32727582), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence Transplantation of CD11b/LIF transgenic BMCs reduces the numbers of FAPs in dystrophic muscle but does not affect phenotype. a QPCR analysis shows that TA muscles from LIF BMT/mdx recipients have reduced Pdgfra gene expression. N = 7 or 8 for WT BMT/mdx and LIF BMT/mdx data sets, respectively, * indicates significantly different from WT BMT/mdx recipients at P < 0.05. P-values based on two-tailed t-test. For all histograms in the figure, the bars indicate mean ± sem. b To quantify the number of FAPs, muscle sections were co-labeled with antibodies to PDGFR alpha (red) and CD31, CD45 (green). Arrowheads indicate FAPs (CD31-CD45-PDGFR alpha +). Bar = 50 μm. c Fewer FAPs (CD31-CD45-PDGFR alpha +) in TA cross-sections of LIF BMT/mdx recipients compared to WT BMT/mdx recipients. N = 5 for each data set. d There was no detectible change in phenotype of PDGFR alpha + cells assayed for co-expression of the fibrogenic marker HSP47. e FACS plots demonstrating strategy for sorting FAPs (Hoechst + CD11b-CD31-CD45-PDGFR alpha +). Fibroblasts derived from FAPs were stimulated with LIF (10 ng/ml) and/or TGF beta 1 (10 ng/ml) for 3 h (f–h) or 3 days (i–k) and assayed by QPCR for Ctgf (f, i), Fn1 (g, j), and Col1a1 (h, k). N = 4 technical replicates for each data set. Significant findings were verified with biological replicates of cells sorted from independent donors. * Indicates significantly different from control cultures, # indicates significantly different from TGF beta 1 treated cultures, and Φ indicates significantly different from LIF-treated cultures at P < 0.05. P-values based on ANOVA with Tukey’s multiple comparison test. Source data are provided as a Source Data file Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31243277), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence Lgr5 is expressed abundantly in villus tip telocytes.a smFISH of Lgr5, DAPI in blue, Scale bar–20 µm. b Blow up of villus tip, Scale bar–10 µm. In a, b thin white arrows point at autofluorescent blobs. c blow up of crypt, Scale bar–10 µm. Red arrows in b–c point to Lgr5 positive cells. dLgr5 mRNA (red dots) expressed in PDGFRa+ VTTs that co-express Bmp4 mRNA (green dots). Scale bar–10 µm. Red arrows point to Lgr5 and Bmp4 double positive cells. e Blow up of the region boxed in d. Scale bar–5 µm. fLgr5 mRNA concentrations in VTTs are comparable to those in Lgr5+ crypt base columnar cells (n = 25 cells examined over 2 mice for each region). Boxes show 25–75 percentiles of the smFISH expression, horizontal red lines are medians. Whiskers, extend to the most extreme data point within 1.5× the interquartile range (IQR) from the box; g) Rspo3 mRNAs are localized on telopodes that extend away from the cell bodies of the VTTs. VTTs are marked by Lgr5 mRNA (red dots), Rspo3 mRNA (green dots) is localized away from the cell body, PDGFRa antibody mark VTTs cell bodies and telopodes. Scale bar–10 µm, in inset, green arrows point to Rspo3 mRNAs (green dots) localized on PDGFRa telopodes (blue). Telocyte cell body is marked by white dashed line. inset Scale bar–5 µm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32321913), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse PDGFR alpha by Immunohistochemistry View Larger

Detection of Mouse PDGFR alpha by Immunohistochemistry PDGFR alpha driven brain tumors display features of high grade glioma.(a–g) Histopathological analysis of tumor areas by H&E staining shows a high concentration of mitotic figures (a, arrows), high cellularity and nuclear atypia (b), perineuronal satellitosis (c; N, neuronal nuclei), perivascular growth (d), intrafascicular growth (e), subarachnoid spreading (f), and areas of incipient necrosis (g; arrows point to pyknotic nuclei). (h–k) IF labeling of brain tumor sections for cell type specific markers. Nuclei labeled with DAPI are shown in blue. Tumor cells with high PDGFR alpha expression were highly proliferative, as seen by proliferation marker Ki67 (h), and express the OPC cell lineage markers Olig2, Sox2, Sox10, and Ng2, as well as the neural stem cell marker Nestin (i–k). Tumor cells were negative for immunosignal of astroglial marker GFAP, mature oligodendrocyte marker APC-CC1, and neuronal marker NeuN (l–n). Scale bars: 10 μm (a–g), 20 μm (h–n). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25683249), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence Lgr5 is expressed abundantly in villus tip telocytes.a smFISH of Lgr5, DAPI in blue, Scale bar–20 µm. b Blow up of villus tip, Scale bar–10 µm. In a, b thin white arrows point at autofluorescent blobs. c blow up of crypt, Scale bar–10 µm. Red arrows in b–c point to Lgr5 positive cells. dLgr5 mRNA (red dots) expressed in PDGFRa+ VTTs that co-express Bmp4 mRNA (green dots). Scale bar–10 µm. Red arrows point to Lgr5 and Bmp4 double positive cells. e Blow up of the region boxed in d. Scale bar–5 µm. fLgr5 mRNA concentrations in VTTs are comparable to those in Lgr5+ crypt base columnar cells (n = 25 cells examined over 2 mice for each region). Boxes show 25–75 percentiles of the smFISH expression, horizontal red lines are medians. Whiskers, extend to the most extreme data point within 1.5× the interquartile range (IQR) from the box; g) Rspo3 mRNAs are localized on telopodes that extend away from the cell bodies of the VTTs. VTTs are marked by Lgr5 mRNA (red dots), Rspo3 mRNA (green dots) is localized away from the cell body, PDGFRa antibody mark VTTs cell bodies and telopodes. Scale bar–10 µm, in inset, green arrows point to Rspo3 mRNAs (green dots) localized on PDGFRa telopodes (blue). Telocyte cell body is marked by white dashed line. inset Scale bar–5 µm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32321913), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence OPC expresses leptin receptors.(a) Representative images of spinal cord sections, which were double-labeled for LepRb (green) in combination with PDGFR alpha (red). Spinal cord sections were obtained 7 days after LPC injection; the graph shows quantification (n = 3). P = 0.007573 (LepRb flox vs intact CKO), 0.0108779 (LepRb flox vs LPC CKO), ANOVA with Tukey’s post-hoc test. (b) Relative expression of leptin receptors mRNA in PDGFR alpha -positive OPC obtained from the brain of PDGFR alpha -creERT:: Lepr flox/flox mice and +/+::Lepr flox/flox mice (n = 5,6). P = 0.005878 (LepRa), 0.010306 (LepRb), 0.001535 (LepRc), 0.003169 (LepRd), 0.030459 (LepRe), Student’s t-test. (c) Representative images of spinal cord sections which were double labeled for BrdU in combination with PDGFR alpha (left panels) and GSTπ (right panels). Sections were prepared 7 days (left panels) and 14 days (right panels) after LPC injection. BrdU was administrated during 3–7 days after LPC injection; the graph shows quantification (n = 5–8). P = 0.029791(PDGFR alpha and BrdU labeled cells), 0.028870 (GSTπ and BrdU labeled cells), Student’s t-test. (d) Representative images of PDGFR alpha expression in the intact spinal cord of PDGFR alpha -creERT:: Lepr flox/flox mice and +/+::Lepr flox/flox mice; the graph shows quantification (n = 3–4). P = 0.404999, Student’s t-test, n.s. indicates no significant difference. (e) Representative images of APC expression in the intact spinal cord of PDGFR alpha -creERT:: Lepr flox/flox mice and +/+::Lepr flox/flox mice; the graph shows quantification (n = 3). P = 0.495667, Student’s t-test, n.s. indicates no significant difference. (f) Representative spinal cord section of PDGFR alpha -creERT:: Lepr flox/flox mice, which were prepared 14 days after LPC injection and stained with MBP; the graph shows quantification of the demyelinating area in the dorsal spinal cord (n = 7 for control, 10 for CKO). P = 0.030688, Student’s t-test. (g) Representative spinal cord sections which were labeled for CD11b. Sections were prepared 7 days after LPC injection. The graph shows quantification (n = 3). P = 0.493264, Student’s t-test, n.s. indicates no significant difference. *P < 0.05, **P < 0.01, error bars represent SEM. Scale bars: 25 μm for (a), 50 μm for high magnification images in (c), 100 μm for others. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep40397), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse PDGFR alpha by Immunocytochemistry/Immunofluorescence Endogenous leptin sustains spontaneous OPC proliferation.(a) Representative images of spinal cord sections, which were prepared 7 days (left panels) and 14 days (right panels) after LPC injection and double labeled for BrdU in combination with PDGFR alpha (upper panels), GSTπ (upper panels) and olig2 (lower panels). BrdU was administrated during 3–7 days after LPC injection; the graph shows quantification (n = 5–8). P = 0.042915 (PDGFR alpha and BrdU labeled cells), 0.013560 (Olig2 and BrdU labeled cells 7 days after injection), 0.012111 (GSTπ and BrdU labeled cells), 0.009797 (Olig2 and BrdU labeled cells 14 days after injection), Student’s t-test. (b) Representative spinal cord sections, which were prepared 14 days after LPC injection and stained with MBP are shown; the graph shows quantification (n = 6). P = 0.025243, Student’s t-test. (c) Representative images of spinal cord section, which were prepared 7 days after LPC injection and labeled for CD11b; the graph shows quantification (n = 4). P = 0.213763, Student’s t-test, n.s. indicates no significant difference. *P < 0.05, **P < 0.01, error bars represent SEM. Scale bar: 50 μm for high magnification images in a, 100 μm for others. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep40397), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse PDGFR alpha by Immunohistochemistry View Larger

Detection of Mouse PDGFR alpha by Immunohistochemistry PDGFR alpha driven brain tumors display features of high grade glioma.(a–g) Histopathological analysis of tumor areas by H&E staining shows a high concentration of mitotic figures (a, arrows), high cellularity and nuclear atypia (b), perineuronal satellitosis (c; N, neuronal nuclei), perivascular growth (d), intrafascicular growth (e), subarachnoid spreading (f), and areas of incipient necrosis (g; arrows point to pyknotic nuclei). (h–k) IF labeling of brain tumor sections for cell type specific markers. Nuclei labeled with DAPI are shown in blue. Tumor cells with high PDGFR alpha expression were highly proliferative, as seen by proliferation marker Ki67 (h), and express the OPC cell lineage markers Olig2, Sox2, Sox10, and Ng2, as well as the neural stem cell marker Nestin (i–k). Tumor cells were negative for immunosignal of astroglial marker GFAP, mature oligodendrocyte marker APC-CC1, and neuronal marker NeuN (l–n). Scale bars: 10 μm (a–g), 20 μm (h–n). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25683249), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse PDGFR alpha by Immunohistochemistry View Larger

Detection of Mouse PDGFR alpha by Immunohistochemistry PDGFR alpha driven brain tumors display features of high grade glioma.(a–g) Histopathological analysis of tumor areas by H&E staining shows a high concentration of mitotic figures (a, arrows), high cellularity and nuclear atypia (b), perineuronal satellitosis (c; N, neuronal nuclei), perivascular growth (d), intrafascicular growth (e), subarachnoid spreading (f), and areas of incipient necrosis (g; arrows point to pyknotic nuclei). (h–k) IF labeling of brain tumor sections for cell type specific markers. Nuclei labeled with DAPI are shown in blue. Tumor cells with high PDGFR alpha expression were highly proliferative, as seen by proliferation marker Ki67 (h), and express the OPC cell lineage markers Olig2, Sox2, Sox10, and Ng2, as well as the neural stem cell marker Nestin (i–k). Tumor cells were negative for immunosignal of astroglial marker GFAP, mature oligodendrocyte marker APC-CC1, and neuronal marker NeuN (l–n). Scale bars: 10 μm (a–g), 20 μm (h–n). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25683249), licensed under a CC-BY license. Not internally tested by R&D Systems.

Flow Cytometry View Larger

Detection of PDGF R alpha in 3T3-L1 cells by Flow Cytometry 3T3-L1 cells were stained with Goat Anti-Mouse PDGF R alpha Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062, filled histogram) or isotype control antibody (Catalog # 4-001-A, open histogram) followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0108). View our protocol for Staining Membrane-associated Proteins.

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Background: PDGF R alpha

The platelet-derived growth factor (PDGF) family consists of proteins derived from four genes (PDGF-A, -B, -C, and -D) that form disulfide-linked homodimers (PDGF-AA, -BB, -CC, and -DD) and a heterodimer (PDGF-AB) (1, 2). These proteins regulate diverse cellular functions by binding to and inducing the homo- or hetero-dimerization of two receptors (PDGF R alpha  and R beta ). Whereas alpha / alpha homo-dimerization is induced by PDGF-AA, -BB, -CC, and -AB, alpha / beta  hetero-dimerization is induced by PDGF-AB, -BB, -CC, and -DD, and beta / beta  homo-dimerization is induced only by PDGF-BB and -DD (1-4). Both PDGF R alpha  and R beta are members of the class III subfamily of receptor tyrosine kinases (RTK) that also includes the receptors for M-CSF, SCF, and Flt-3 ligand. All class III RTKs are characterized by the presence of five immunoglobulin-like domains in their extracellular region and a split kinase domain in their intracellular region. Ligand-induced receptor dimerization results in autophosphorylation in trans resulting in the activation of several intracellular signaling pathways that can lead to cell proliferation, cell survival, cytoskeletal rearrangement, and cell migration. Many cell types, including fibroblasts and smooth muscle cells, express both the alpha  and beta  receptors. Others have only the alpha  receptors (oligodendrocyte progenitor cells, mesothelial cells, liver sinusoidal endothelial cells, astrocytes, platelets, and megakaryocytes) or only the  beta receptors (myoblasts, capillary endothelial cells, pericytes, T cells, myeloid hematopoietic cells, and macrophages) (1, 2). Recombinant mouse and human soluble PDGF R beta  bind PDGF with high affinity and are potent PDGF antagonists.

References
  1. Betsholtz, C. et al. (2001) BioEssays 23:494.
  2. Ostman, A. and A.H. Heldin (2001) Advances in Cancer Research 80:1.
  3. Gilbertson, D. et al. (2001) J. Biol. Chem. 276:27406.
  4. LaRochells, W.J. et al. (2001) Nature Cell Biol. 3:517.
Long Name
Platelet-derived Growth Factor Receptor alpha
Entrez Gene IDs
5156 (Human); 18595 (Mouse)
Alternate Names
alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; CD140a; EC 2.7.10; EC 2.7.10.1; MGC74795; PDGF R alpha; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA/BCR fusion; PDGF-R-alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein; RHEPDGFRA

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Citations for Mouse PDGF R alpha Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

298 Citations: Showing 1 - 10
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  1. Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration
    Authors: Reggio A, Rosina M, Krahmer N et al.
    Life Sci Alliance.
  2. Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon
    Authors: Mary Jo Talley, Diana Nardini, Lisa A. Ehrman, Q. Richard Lu, Ronald R. Waclaw
    Neural Dev
  3. The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic Neocortex
    Authors: Himari Ogino, Tsuzumi Nakajima, Yuki Hirota, Kohki Toriuchi, Mineyoshi Aoyama, Kazunori Nakajima et al.
    The Journal of Neuroscience
  4. Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate wounds
    Authors: Quan M Phan, Gracelyn M Fine, Lucia Salz, Gerardo G Herrera, Ben Wildman, Iwona M Driskell et al.
    eLife
  5. Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice
    Authors: O'Shea TM, Ao Y, Wang S et al.
    Nature Communications
  6. Suppression of proteolipid protein rescues Pelizaeus–Merzbacher disease
    Authors: Matthew S. Elitt, Lilianne Barbar, H. Elizabeth Shick, Berit E. Powers, Yuka Maeno-Hikichi, Mayur Madhavan et al.
    Nature
  7. CD200 restrains macrophage attack on oligodendrocyte precursors via toll-like receptor 4 downregulation.
    Authors: Hayakawa K, Pham LDD, Seo JH et al.
    J Cereb Blood Flow Metab.
  8. Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration
    Authors: Malea M. Murphy, Jennifer A. Lawson, Sam J. Mathew, David A. Hutcheson, Gabrielle Kardon
    Development
  9. Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation
    Authors: Gesine M. Scharf, Katja Kilian, Julio Cordero, Yong Wang, Andrea Grund, Melanie Hofmann et al.
    JCI Insight
  10. Targeting TrkB with a Brain-Derived Neurotrophic Factor Mimetic Promotes Myelin Repair in the Brain
    Authors: Jessica L. Fletcher, Rhiannon J. Wood, Jacqueline Nguyen, Eleanor M.L. Norman, Christine M.K. Jun, Alexa R. Prawdiuk et al.
    The Journal of Neuroscience
  11. Cell type-specific labeling of newly synthesized proteins by puromycin inactivation
    Authors: Cabrera-Cabrera F, Tull H, Capuana R et al.
    Journal of Biological Chemistry
  12. Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury
    Authors: Palikuqi B, Rispal J, Reyes EA et al.
    Cell stem cell
  13. Integrated high-confidence and high-throughput approaches for quantifying synapse engulfment by oligodendrocyte precursor cells
    Authors: Jessica A. Kahng, Andre M. Xavier, Austin Ferro, Yohan S.S. Auguste, Lucas Cheadle
    bioRxiv
  14. Col1a2-Deleted Mice Have Defective Type I Collagen and Secondary Reactive Cardiac Fibrosis with Altered Hypertrophic Dynamics
    Authors: Bowers SLK, Meng Q, Kuwabara Y et al.
    Cells
  15. TrkB Agonist LM22A-4 Increases Oligodendroglial Populations During Myelin Repair in the Corpus Callosum
    Authors: Huynh T. H. Nguyen, Rhiannon J. Wood, Alexa R. Prawdiuk, Sebastian G. B. Furness, Junhua Xiao, Simon S. Murray et al.
    Frontiers in Molecular Neuroscience
  16. The Neurotrophic Receptor Tyrosine Kinase in MEC-mPFC Neurons Contributes to Remote Memory Consolidation
    Authors: Jongryul Hong, Yeonji Jeong, Won Do Heo
    The Journal of Neuroscience
  17. Loss of Acta2 in cardiac fibroblasts does not prevent the myofibroblast differentiation or affect the cardiac repair after myocardial infarction
    Authors: Li Y, Li C, Liu Q et al.
    Journal of molecular and cellular cardiology
  18. Roles of A-kinase Anchor Protein 12 in Astrocyte and Oligodendrocyte Precursor Cell in Postnatal Corpus Callosum
    Authors: Hajime Takase, Gen Hamanaka, Ryo Ohtomo, Ji Hyun Park, Kelly K. Chung, Irwin H. Gelman et al.
    Stem Cell Reviews and Reports
  19. A role for sustained MAPK activity in the mouse ventral telencephalon
    Authors: Mary Jo Talley, Diana Nardini, Shenyue Qin, Carlos E. Prada, Lisa A. Ehrman, Ronald R. Waclaw
    Developmental Biology
  20. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells
    Authors: Yulia Shwartz, Meryem Gonzalez-Celeiro, Chih-Lung Chen, H. Amalia Pasolli, Shu-Hsien Sheu, Sabrina Mai-Yi Fan et al.
    Cell
  21. Identification and classification of interstitial cells in the mouse renal pelvis
    Authors: Nathan Grainger, Ryan S. Freeman, Cameron C. Shonnard, Bernard T. Drumm, Sang Don Koh, Sean M. Ward et al.
    The Journal of Physiology
  22. Brown Fat Promotes Muscle Growth During Regeneration
    Authors: Anna R. Bryniarski, Gretchen A. Meyer
    Journal of Orthopaedic Research
  23. Single-Nucleus Profiling Identifies Accelerated Oligodendrocyte Precursor Cell Senescence in a Mouse Model of Down Syndrome
    Authors: Bianca Rusu, Bharti Kukreja, Taiyi Wu, Sophie J. Dan, Min Yi Feng, Brian T. Kalish
    eNeuro
  24. A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours
    Authors: Hamed AA, Kunz DJ, El-Hamamy I et al.
    Nature communications
  25. Deconstructing cold-induced brown adipocyte neogenesis in mice
    Authors: Rayanne B Burl, Elizabeth Ann Rondini, Hongguang Wei, Roger Pique-Regi, James G Granneman
    eLife
  26. Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis
    Authors: Daniel Kopinke, Elle C. Roberson, Jeremy F. Reiter
    Cell
  27. Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation
    Authors: Anthony Fernández-Castañeda, Peiwen Lu, Anna C. Geraghty, Eric Song, Myoung-Hwa Lee, Jamie Wood et al.
    Cell
  28. Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state
    Authors: Yingzi Liu, Christian F. Guerrero-Juarez, Fei Xiao, Nitish Udupi Shettigar, Raul Ramos, Chen-Hsiang Kuan et al.
    Developmental Cell
  29. Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity
    Authors: Akitoshi Hara, Katsuhiro Kato, Toshikazu Ishihara, Hiroki Kobayashi, Naoya Asai, Shinji Mii et al.
    Genes to Cells
  30. Infiltration of intramuscular adipose tissue impairs skeletal muscle contraction
    Authors: Nicole K. Biltz, Kelsey H. Collins, Karen C. Shen, Kendall Schwartz, Charles A. Harris, Gretchen A. Meyer
    The Journal of Physiology
  31. Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment
    Authors: Anna C. Geraghty, Erin M. Gibson, Reem A. Ghanem, Jacob J. Greene, Alfonso Ocampo, Andrea K. Goldstein et al.
    Neuron
  32. Neuropilin-1 and platelet-derived growth factor receptors cooperatively regulate intermediate filaments and mesenchymal cell migration during alveolar septation
    Authors: Stephen E. McGowan, Diann M. McCoy
    American Journal of Physiology-Lung Cellular and Molecular Physiology
  33. alpha -Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy
    Authors: Benjamin Ettle, Bilal E. Kerman, Elvira Valera, Clarissa Gillmann, Johannes C. M. Schlachetzki, Simone Reiprich et al.
    Acta Neuropathologica
  34. Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System
    Authors: Loic Auderset, Carlie L. Cullen, Kaylene M. Young
    PLOS ONE
  35. Expansion and Contraction of the Umbrella Cell Apical Junctional Ring in Response to Bladder Filling and Voiding
    Authors: Eaton AF, Clayton DR, Ruiz WG et al.
    Mol. Biol. Cell
  36. Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
    Authors: Toshiro Hara, Rony Chanoch-Myers, Nathan D. Mathewson, Chad Myskiw, Lyla Atta, Lillian Bussema et al.
    Cancer Cell
  37. Cell fate determining molecular switches and signaling pathways in Pax7-expressing somitic mesoderm
    Authors: Cheuk Wang Fung, Shaopu Zhou, Han Zhu, Xiuqing Wei, Zhenguo Wu, Angela Ruohao Wu
    Cell Discovery
  38. Analysis of the influences of social isolation on cognition and the therapeutic potential of deep brain stimulation in a mouse model
    Authors: Yun-Yun Hu, Xuan-Si Ding, Gang Yang, Xue-Song Liang, Lei Feng, Yan-Yun Sun et al.
    Frontiers in Psychiatry
  39. Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI-1-TGF-?-myoCAF-Dependent Mechanism
    Authors: Wu J, Jing X, Du Q et al.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany)
  40. Generation of a Mouse Model to Study the Noonan Syndrome Gene Lztr1 in the Telencephalon
    Authors: Mary Jo Talley, Diana Nardini, Nisha Shabbir, Lisa A. Ehrman, Carlos E. Prada, Ronald R. Waclaw
    Frontiers in Cell and Developmental Biology
  41. Optic vesicle morphogenesis requires primary cilia
    Authors: Luciano Fiore, Nozomu Takata, Sandra Acosta, Wanshu Ma, Tanushree Pandit, Michael Oxendine et al.
    Developmental Biology
  42. Mapping growth-factor-modulated Akt signaling dynamics
    Authors: Sean M. Gross, Peter Rotwein
    Development
  43. Circulating transforming growth factor-beta 1 facilitates remyelination in the adult central nervous system
    Authors: Machika Hamaguchi, Rieko Muramatsu, Harutoshi Fujimura, Hideki Mochizuki, Hirotoshi Kataoka, Toshihide Yamashita
    eLife
  44. Stromal cells maintain immune cell homeostasis in adipose tissue via production of interleukin-33
    Authors: T. Mahlakõiv, A.-L. Flamar, L. K. Johnston, S. Moriyama, G. G. Putzel, P. J. Bryce et al.
    Science Immunology
  45. Wild-type and SAMP8 mice show age-dependent changes in distinct stem cell compartments of the interfollicular epidermis
    Authors: Gopakumar Changarathil, Karina Ramirez, Hiroko Isoda, Aiko Sada, Hiromi Yanagisawa
    PLOS ONE
  46. It takes two to tango: cardiac fibroblast-derived NO-induced cGMP enters cardiac myocytes and increases cAMP by inhibiting PDE3
    Authors: Lukas Menges, Jan Giesen, Kerem Yilmaz, Evanthia Mergia, Annette Füchtbauer, Ernst-Martin Füchtbauer et al.
    Communications Biology
  47. The Tcf21 lineage constitutes the lung lipofibroblast population
    Authors: Juwon Park, Malina J. Ivey, Yanik Deana, Kara L. Riggsbee, Emelie Sörensen, Veronika Schwabl et al.
    American Journal of Physiology-Lung Cellular and Molecular Physiology
  48. Adherent muscle connective tissue fibroblasts are phenotypically and biochemically equivalent to stromal fibro/adipogenic progenitors
    Authors: Osvaldo Contreras, Fabio M. Rossi, Enrique Brandan
    Matrix Biology Plus
  49. Mesothelial mobilization in the developing lung and heart differs in timing, quantity, and pathway dependency
    Authors: Timo H. Lüdtke, Carsten Rudat, Jennifer Kurz, Regine Häfner, Franziska Greulich, Irina Wojahn et al.
    American Journal of Physiology-Lung Cellular and Molecular Physiology
  50. Characterization of porcine extraembryonic endoderm cells
    Authors: Qiao‐Yan Shen, Shuai Yu, Ying Zhang, Zhe Zhou, Zhen‐Shuo Zhu, Qin Pan et al.
    Cell Proliferation
  51. PDGF Modulates BMP2-Induced Osteogenesis in Periosteal Progenitor Cells
    Authors: Xi Wang, Brya G Matthews, Jungeun Yu, Sanja Novak, Danka Grcevic, Archana Sanjay et al.
    JBMR Plus
  52. Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap.
    Authors: Nurnberg ST, Cheng K, Raiesdana A et al.
    PLoS Genet
  53. Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis
    Authors: Kornélia Baghy, Zsolt Horváth, Eszter Regős, Katalin Kiss, Zsuzsa Schaff, Renato V. Iozzo et al.
    FEBS Journal
  54. The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord.
    Authors: Zhang S, RaSai A, Wang Y et al.
    Mol. Neurobiol.
  55. Fibroblast-derived EGF ligand Neuregulin-1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth
    Authors: TT Lemmetyine, EW Viitala, L Wartiovaar, T Kaprio, J Hagström, C Haglund, P Katajisto, TC Wang, E Domènech-M, S Ollila
    Disease Models & Mechanisms, 2023-04-03;0(0):.
  56. Peripheral Nerve Single-Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth
    Authors: Jeremy S. Toma, Konstantina Karamboulas, Matthew J. Carr, Adelaida Kolaj, Scott A. Yuzwa, Neemat Mahmud et al.
    eNeuro
  57. Inhibiting Bone Morphogenetic Protein 4 Type I Receptor Signaling Promotes Remyelination by Potentiating Oligodendrocyte Differentiation
    Authors: Alistair E. Govier-Cole, Rhiannon J. Wood, Jessica L. Fletcher, David G. Gonsalvez, Daniel Merlo, Holly S. Cate et al.
    eNeuro
  58. Defining the lineage of thermogenic perivascular adipose tissue
    Authors: Anthony R. Angueira, Alexander P. Sakers, Corey D. Holman, Lan Cheng, Michelangella N. Arbocco, Farnaz Shamsi et al.
    Nature Metabolism
  59. WNT7A suppresses adipogenesis of skeletal muscle mesenchymal stem cells and fatty infiltration through the alternative Wnt-Rho-YAP/TAZ signaling axis
    Authors: Chengcheng Fu, Britney Chin-Young, GaYoung Park, Mariana Guzmán-Seda, Damien Laudier, Woojin M. Han
    Stem Cell Reports
  60. Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome
    Authors: Salome M. Brütsch, Elizabeta Madzharova, Sophia Pantasis, Till Wüstemann, Selina Gurri, Heiko Steenbock et al.
    Cellular and Molecular Life Sciences
  61. Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-kappa B pathway
    Authors: Xiao-Ru Ma, Shu-Ying Yang, Shuang-Shuang Zheng, Huan-Huan Yan, Hui-Min Gu, Fan Wang et al.
    Cell Death Discovery
  62. A novel post-synaptic signal pathway of sympathetic neural regulation of murine colonic motility
    Authors: Masaaki Kurahashi, Yoshihiko Kito, Salah A. Baker, Libby K. Jennings, James G. R. Dowers, Sang Don Koh et al.
    The FASEB Journal
  63. Lineage tracing of Foxd1‐expressing embryonic progenitors to assess the role of divergent embryonic lineages on adult dermal fibroblast function
    Authors: John T. Walker, Lauren E. Flynn, Douglas W. Hamilton
    FASEB BioAdvances
  64. Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling
    Authors: V Chitu, F Biundo, GGL Shlager, ES Park, P Wang, ME Gulinello, ? Gokhan, HC Ketchum, K Saha, MA DeTure, DW Dickson, ZK Wszolek, D Zheng, AL Croxford, B Becher, D Sun, MF Mehler, ER Stanley
    Cell Rep, 2020-03-03;30(9):3004-3019.e5.
  65. Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
    Authors: Yuji Tsuchikawa, Naosuke Kamei, Yohei Sanada, Toshio Nakamae, Takahiro Harada, Kazunori Imaizumi et al.
    Neural Plasticity
  66. Cross-talk between TGF-beta and PDGFR alpha signaling pathways regulates the fate of stromal fibro-adipogenic progenitors
    Authors: Osvaldo Contreras, Meilyn Cruz-Soca, Marine Theret, Hesham Soliman, Lin Wei Tung, Elena Groppa et al.
    Journal of Cell Science
  67. Selective ablation of Nfix in macrophages attenuates muscular dystrophy by inhibiting fibro-adipogenic progenitor-dependent fibrosis
    Authors: Saclier M, Angelini G, Bonfanti C et al.
    The Journal of pathology
  68. Novel guanidine compounds inhibit platelet‐derived growth factor receptor alpha transcription and oligodendrocyte precursor cell proliferation
    Authors: Jelena Medved, William M. Wood, Michael D. van Heyst, Amin Sherafat, Ju‐Young Song, Sagune Sakya et al.
    Glia
  69. Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury
    Authors: DO Dias, H Kim, D Holl, B Werne Soln, J Lundeberg, M Carlén, C Göritz, J Frisén
    Cell, 2018-03-01;173(1):153-165.e22.
  70. Osteogenic potential of alpha smooth muscle actin expressing muscle resident progenitor cells
    Authors: Brya G. Matthews, Elena Torreggiani, Emilie Roeder, Igor Matic, Danka Grcevic, Ivo Kalajzic
    Bone
  71. Remyelination protects neurons from DLK-mediated neurodegeneration.
    Authors: Duncan, GJ;Ingram, SD;Emberley, K;Hill, J;Cordano, C;Abdelhak, A;McCane, M;Jenks, JE;Jabassini, N;Ananth, K;Ferrara, SJ;Stedelin, B;Sivyer, B;Aicher, SA;Scanlan, TS;Watkins, TA;Mishra, A;Nelson, JW;Green, AJ;Emery, B;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  72. Protein kinase N promotes cardiac fibrosis in heart failure by fibroblast-to-myofibroblast conversion
    Authors: Yoshida, S;Yoshida, T;Inukai, K;Kato, K;Yura, Y;Hattori, T;Enomoto, A;Ohashi, K;Okumura, T;Ouchi, N;Kawase, H;Wettschureck, N;Offermanns, S;Murohara, T;Takefuji, M;
    Nature communications
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Immunocytochemistry
  73. Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics
    Authors: Liu, Y;Yin, M;Mao, X;Wu, S;Wei, S;Heng, S;Yang, Y;Huang, J;Guo, Z;Li, C;Ji, C;Hu, L;Liu, W;Zhang, LJ;
    eLife
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  74. Dynamic upregulation of retinoic acid signal in the early postnatal murine heart promotes cardiomyocyte cell cycle exit and maturation
    Authors: Fujikawa, Y;Kato, K;Unno, K;Narita, S;Okuno, Y;Sato, Y;Takefuji, M;Murohara, T;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  75. A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome
    Authors: Ahuja, K;Vandenabeele, M;Nami, F;Lefevere, E;Van Hoecke, J;Bergmans, S;Claes, M;Vervliet, T;Neyrinck, K;Burg, T;De Herdt, D;Bhaskar, P;Zhu, Y;Looser, ZJ;Loncke, J;Gsell, W;Plaas, M;Agostinis, P;Swinnen, JV;Van Den Bosch, L;Bultynck, G;Saab, AS;Wolfs, E;Chai, YC;Himmelreich, U;Verfaillie, C;Moons, L;De Groef, L;
    Acta neuropathologica communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  76. Mitochondrial network reorganization and transient expansion during oligodendrocyte generation
    Authors: Bame, X;Hill, RA;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  77. Transcription Factors Sox8 and Sox10 Contribute with Different Importance to the Maintenance of Mature Oligodendrocytes
    Authors: Jörg, LM;Schlötzer-Schrehardt, U;Lefebvre, V;Sock, E;Wegner, M;
    International journal of molecular sciences
    Species: Mouse
    Sample Types:
    Applications: Immunohistochemistry-Frozen
  78. Multisensory gamma stimulation mitigates the effects of demyelination induced by cuprizone in male mice
    Authors: Rodrigues-Amorim, D;Bozzelli, PL;Kim, T;Liu, L;Gibson, O;Yang, CY;Murdock, MH;Galiana-Melendez, F;Schatz, B;Davison, A;Islam, MR;Shin Park, D;Raju, RM;Abdurrob, F;Nelson, AJ;Min Ren, J;Yang, V;Stokes, MP;Tsai, LH;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  79. Secretome analysis of oligodendrocytes and precursors reveals their roles as contributors to the extracellular matrix and potential regulators of inflammation
    Authors: Godoy, MI;Pandey, V;Wohlschlegel, JA;Zhang, Y;
    bioRxiv : the preprint server for biology
    Species: Rat
    Sample Types: Whole Cells
    Applications: Immunocytochemistry
  80. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
    Authors: Widjaja, AA;Lim, WW;Viswanathan, S;Chothani, S;Corden, B;Dasan, CM;Goh, JWT;Lim, R;Singh, BK;Tan, J;Pua, CJ;Lim, SY;Adami, E;Schafer, S;George, BL;Sweeney, M;Xie, C;Tripathi, M;Sims, NA;Hübner, N;Petretto, E;Withers, DJ;Ho, L;Gil, J;Carling, D;Cook, SA;
    Nature
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  81. Morphotype-specific calcium signaling in human microglia
    Authors: Nevelchuk, S;Brawek, B;Schwarz, N;Valiente-Gabioud, A;Wuttke, TV;Kovalchuk, Y;Koch, H;Höllig, A;Steiner, F;Figarella, K;Griesbeck, O;Garaschuk, O;
    Journal of neuroinflammation
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  82. The fate of secretory cells during intestinal homeostasis, regeneration, and tumor formation is regulated by Tcf4
    Authors: Janeckova, L;Stastna, M;Hrckulak, D;Berkova, L;Kubovciak, J;Onhajzer, J;Kriz, V;Dostalikova, S;Mullerova, T;Vecerkova, K;Tenglerova, M;Coufal, S;Kostovcikova, K;Blumberg, RS;Filipp, D;Basler, K;Valenta, T;Kolar, M;Korinek, V;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  83. Voltage-Gated Ion Channels Are Transcriptional Targets of Sox10 during Oligodendrocyte Development
    Authors: Peters, C;Aberle, T;Sock, E;Brunner, J;Küspert, M;Hillgärtner, S;Wüst, HM;Wegner, M;
    Cells
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  84. Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice
    Authors: Pan, Y;Hysinger, JD;Yalç?n, B;Lennon, JJ;Byun, YG;Raghavan, P;Schindler, NF;Anastasaki, C;Chatterjee, J;Ni, L;Xu, H;Malacon, K;Jahan, SM;Ivec, AE;Aghoghovwia, BE;Mount, CW;Nagaraja, S;Scheaffer, S;Attardi, LD;Gutmann, DH;Monje, M;
    Nature neuroscience
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  85. Vegfc-expressing cells form heterotopic bone after musculoskeletal injury
    Authors: Vishlaghi, N;Guo, L;Griswold-Wheeler, D;Sun, Y;Booker, C;Crossley, JL;Bancroft, AC;Juan, C;Korlakunta, S;Ramesh, S;Pagani, CA;Xu, L;James, AW;Tower, RJ;Dellinger, M;Levi, B;
    Cell reports
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  86. Dmd mdx mice have defective oligodendrogenesis, delayed myelin compaction and persistent hypomyelination
    Authors: Arreguin, AJ;Shao, Z;Colognato, H;
    Disease models & mechanisms
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  87. ?1 integrins play a critical role maintaining vascular integrity in the hypoxic spinal cord, particularly in white matter
    Authors: Halder, SK;Sapkota, A;Milner, R;
    Acta neuropathologica communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  88. Obesity Facilitates Sex-Specific Improvement In Cognition And Neuronal Function In A Rat Model Of Alzheimer's Disease
    Authors: Lai, AY;Almanza, DLV;Ribeiro, JA;Hill, ME;Mandrozos, M;Koletar, MM;Stefanovic, B;McLaurin, J;
    bioRxiv : the preprint server for biology
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  89. DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts
    Authors: Shumliakivska, M;Luxán, G;Hemmerling, I;Scheller, M;Li, X;Müller-Tidow, C;Schuhmacher, B;Sun, Z;Dendorfer, A;Debes, A;Glaser, SF;Muhly-Reinholz, M;Kirschbaum, K;Hoffmann, J;Nagel, E;Puntmann, VO;Cremer, S;Leuschner, F;Abplanalp, WT;John, D;Zeiher, AM;Dimmeler, S;
    Nature communications
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  90. Synaptic-like transmission between neural axons and arteriolar smooth muscle cells drives cerebral neurovascular coupling
    Authors: Zhang, D;Ruan, J;Peng, S;Li, J;Hu, X;Zhang, Y;Zhang, T;Ge, Y;Zhu, Z;Xiao, X;Zhu, Y;Li, X;Li, T;Zhou, L;Gao, Q;Zheng, G;Zhao, B;Li, X;Zhu, Y;Wu, J;Li, W;Zhao, J;Ge, WP;Xu, T;Jia, JM;
    Nature neuroscience
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Immunocytochemistry
  91. Mertk-expressing microglia influence oligodendrogenesis and myelin modelling in the CNS
    Authors: Nguyen, LT;Aprico, A;Nwoke, E;Walsh, AD;Blades, F;Avneri, R;Martin, E;Zalc, B;Kilpatrick, TJ;Binder, MD;
    Journal of neuroinflammation
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  92. Dicer deficiency in microglia leads to accelerated demyelination and failed remyelination
    Authors: Tripathi, A;Rai, N;Perles, A;Jones, C;Dutta, R;
    bioRxiv : the preprint server for biology
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  93. Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing
    Authors: He, S;Guo, Z;Zhou, M;Wang, H;Zhang, Z;Shi, M;Li, X;Yang, X;He, L;
    Cell stem cell
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  94. IL-6 trans-signaling in a humanized mouse model of scleroderma
    Authors: Odell, ID;Agrawal, K;Sefik, E;Odell, AV;Caves, E;Kirkiles-Smith, NC;Horsley, V;Hinchcliff, M;Pober, JS;Kluger, Y;Flavell, RA;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Xenograft
    Sample Types: Whole Tissue
    Applications: IHC
  95. Col1a2-Deleted Mice Have Defective Type I Collagen and Secondary Reactive Cardiac Fibrosis with Altered Hypertrophic Dynamics
    Authors: Bowers SLK, Meng Q, Kuwabara Y et al.
    Cells
  96. Emergent mechanical control of vascular morphogenesis
    Authors: Whisler, J;Shahreza, S;Schlegelmilch, K;Ege, N;Javanmardi, Y;Malandrino, A;Agrawal, A;Fantin, A;Serwinski, B;Azizgolshani, H;Park, C;Shone, V;Demuren, OO;Del Rosario, A;Butty, VL;Holroyd, N;Domart, MC;Hooper, S;Szita, N;Boyer, LA;Walker-Samuel, S;Djordjevic, B;Sheridan, GK;Collinson, L;Calvo, F;Ruhrberg, C;Sahai, E;Kamm, R;Moeendarbary, E;
    Science advances
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  97. Cell type-specific labeling of newly synthesized proteins by puromycin inactivation
    Authors: Cabrera-Cabrera F, Tull H, Capuana R et al.
    Journal of Biological Chemistry
  98. Endocytic vesicles act as vehicles for glucose uptake in response to growth factor stimulation
    Authors: Tsutsumi, R;Ueberheide, B;Liang, FX;Neel, BG;Sakai, R;Saito, Y;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Immunocytochemistry
  99. A cellular and molecular spatial atlas of dystrophic muscle
    Authors: Stec, MJ;Su, Q;Adler, C;Zhang, L;Golann, DR;Khan, NP;Panagis, L;Villalta, SA;Ni, M;Wei, Y;Walls, JR;Murphy, AJ;Yancopoulos, GD;Atwal, GS;Kleiner, S;Halasz, G;Sleeman, MW;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  100. Spinal Cord Blood Vessels in Aged Mice Show Greater Levels of Hypoxia-Induced Vascular Disruption and Microglial Activation
    Authors: Halder, SK;Milner, R;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  101. Transcriptome analysis of mesenchymal stromal cells of the large and small intestinal smooth muscle layers reveals a unique gastrontestinal stromal signature
    Authors: Chaen, T;Kurosawa, T;Kishi, K;Kaji, N;Ikemoto-Uezumi, M;Uezumi, A;Hori, M;
    Biochemistry and biophysics reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  102. Patterning and folding of intestinal villi by active mesenchymal dewetting
    Authors: Huycke, TR;Miyazaki, H;Häkkinen, TJ;Srivastava, V;Barruet, E;McGinnis, CS;Kalantari, A;Cornwall-Scoones, J;Vaka, D;Zhu, Q;Jo, H;DeGrado, WF;Thomson, M;Garikipati, K;Boffelli, D;Klein, OD;Gartner, ZJ;
    bioRxiv : the preprint server for biology
    Species: Xenograft
    Sample Types: Organoid
    Applications: Bioassay
  103. Hedgehog signaling via its ligand DHH acts as cell fate determinant during skeletal muscle regeneration
    Authors: Norris, AM;Appu, AB;Johnson, CD;Zhou, LY;McKellar, DW;Renault, MA;Hammers, D;Cosgrove, BD;Kopinke, D;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  104. Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
    Authors: Sun, L;Zhang, X;Wu, S;Liu, Y;Guerrero-Juarez, CF;Liu, W;Huang, J;Yao, Q;Yin, M;Li, J;Ramos, R;Liao, Y;Wu, R;Xia, T;Zhang, X;Yang, Y;Li, F;Heng, S;Zhang, W;Yang, M;Tzeng, CM;Ji, C;Plikus, MV;Gallo, RL;Zhang, LJ;
    Cell reports
  105. Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme
    Authors: Alber, AB;Marquez, HA;Ma, L;Kwong, G;Thapa, BR;Villacorta-Martin, C;Lindstrom-Vautrin, J;Bawa, P;Wang, F;Luo, Y;Ikonomou, L;Shi, W;Kotton, DN;
    Nature communications
    Species: Transgenic Mouse
    Sample Types: Organoid
    Applications: Immunohistochemistry
  106. PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development
    Authors: Waldhauser, V;Baroti, T;Fröb, F;Wegner, M;
    Cells
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  107. Wound infiltrating adipocytes are not myofibroblasts
    Authors: Kalgudde Gopal, S;Dai, R;Stefanska, AM;Ansari, M;Zhao, J;Ramesh, P;Bagnoli, JW;Correa-Gallegos, D;Lin, Y;Christ, S;Angelidis, I;Lupperger, V;Marr, C;Davies, LC;Enard, W;Machens, HG;Schiller, HB;Jiang, D;Rinkevich, Y;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  108. SUMOylation of PDGF receptor ? affects signaling via PLC? and STAT3, and cell proliferation
    Authors: Wang, K;Papadopoulos, N;Hamidi, A;Lennartsson, J;Heldin, CH;
    BMC molecular and cell biology
    Species: African Green Monkey, Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: Immunoprecipitation, IHC, Western Blot
  109. Glial progenitor heterogeneity and key regulators revealed by single-cell RNA sequencing provide insight to regeneration in spinal cord injury
    Authors: Wei, H;Wu, X;Withrow, J;Cuevas-Diaz Duran, R;Singh, S;Chaboub, LS;Rakshit, J;Mejia, J;Rolfe, A;Herrera, JJ;Horner, PJ;Wu, JQ;
    Cell reports
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  110. The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
    Authors: A Kolaj, SK Zahr, BS Wang, T Krawec, H Kazan, G Yang, DR Kaplan, FD Miller
    Cell Reports, 2023-03-15;42(3):112242.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  111. Structure, signals, and cellular elements of the mouse gastric mesenchymal niche
    Authors: E Manieri, G Tie, D Seruggia, S Madha, A Maglieri, K Huang, Y Fujiwara, K Zhang, S Orkin, R He, N McCarthy, RA Shivdasani
    bioRxiv : the preprint server for biology, 2023-02-24;0(0):.
    Species: Mouse
    Sample Types: Organoid
    Applications: IHC
  112. Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner
    Authors: K Hoeft, GJL Schaefer, H Kim, D Schumacher, T Bleckwehl, Q Long, BM Klinkhamme, F Peisker, L Koch, J Nagai, M Halder, S Ziegler, E Liehn, C Kuppe, J Kranz, S Menzel, I Costa, A Wahida, P Boor, RK Schneider, S Hayat, R Kramann
    Cell Reports, 2023-02-17;42(2):112131.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  113. Angiogenesis precedes myogenesis during regeneration following biopsy injury of skeletal muscle
    Authors: NL Jacobsen, AB Morton, SS Segal
    Skeletal Muscle, 2023-02-14;13(1):3.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  114. Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
    Authors: ME Mohr, S Li, AM Trouten, RA Stairley, PL Roddy, C Liu, M Zhang, HM Sucov, G Tao
    bioRxiv : the preprint server for biology, 2023-02-08;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  115. Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress
    Authors: Z Li, K Chen, Q Shao, H Lu, X Zhang, Y Pu, X Sun, H He, L Cao
    Journal of Neuroinflammation, 2023-01-30;20(1):16.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  116. Discoidin domain receptor 2 regulates aberrant mesenchymal lineage cell fate and matrix organization
    Authors: CA Pagani, AC Bancroft, RJ Tower, N Livingston, Y Sun, JY Hong, RN Kent, AL Strong, JH Nunez, JMR Medrano, N Patel, BA Nanes, KM Dean, Z Li, C Ge, BM Baker, AW James, SJ Weiss, RT Franceschi, B Levi
    Science Advances, 2022-12-21;8(51):eabq6152.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  117. Effects of MgSO4 Alone or Associated with 4-PBA on Behavior and White Matter Integrity in a Mouse Model of Cerebral Palsy: A Sex- and Time-Dependent Study
    Authors: L Legouez, B Le Dieu-Lu, S Feillet, G Riou, M Yeddou, T Plouchart, N Dourmap, MA Le Ray, S Marret, BJ Gonzalez, C Cleren
    International Journal of Molecular Sciences, 2022-12-15;23(24):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  118. Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic stroke
    Authors: X Hong, Y Jian, S Ding, J Zhou, X Zheng, H Zhang, B Zhou, C Zhuang, J Wan, X Tong
    EBioMedicine, 2022-12-15;87(0):104406.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  119. DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal
    Authors: P Cattaneo, MGB Hayes, N Baumgarten, D Hecker, S Peruzzo, GS Aslan, P Kunderfran, V Larcher, L Zhang, R Contu, G Fonseca, S Spinozzi, J Chen, G Condorelli, S Dimmeler, MH Schulz, S Heinz, N Guimarães-, SM Evans
    Nature Communications, 2022-12-02;13(1):7444.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  120. Ultrastructural characteristics of oligodendrocyte precursor cells in the early postnatal mouse optic nerve observed by serial block-face scanning electron microscopy
    Authors: K Ono, H Gotoh, T Nomura, T Morita, O Baba, M Matsumoto, S Saitoh, N Ohno
    PLoS ONE, 2022-12-01;17(12):e0278118.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  121. KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF
    Authors: C Bernhardt, E Sock, F Fröb, S Hillgärtne, M Nemer, M Wegner
    Nucleic Acids Research, 2022-11-11;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  122. CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging
    Authors: T Kaya, N Mattugini, L Liu, H Ji, L Cantuti-Ca, J Wu, M Schifferer, J Groh, R Martini, S Besson-Gir, S Kaji, A Liesz, O Gokce, M Simons
    Nature Neuroscience, 2022-10-24;25(11):1446-1457.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  123. Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice
    Authors: O'Shea TM, Ao Y, Wang S et al.
    Nature Communications
  124. Vaccination-based immunotherapy to target profibrotic cells in liver and lung
    Authors: M Sobecki, J Chen, E Krzywinska, S Nagarajan, Z Fan, E Nelius, JM Monné Rodr, F Seehusen, A Hussein, G Moschini, EY Hajam, R Kiran, D Gotthardt, J Debbache, C Badoual, T Sato, T Isagawa, N Takeda, C Tanchot, E Tartour, A Weber, S Werner, J Loffing, L Sommer, V Sexl, C Münz, C Feghali-Bo, E Pachera, O Distler, J Snedeker, C Jamora, C Stockmann
    Cell Stem Cell, 2022-09-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Flow Cytometry, IHC
  125. Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain
    Authors: RM Beiter, C Rivet-Noor, AR Merchak, R Bai, DM Johanson, E Slogar, K Sol-Church, CC Overall, A Gaultier
    Scientific Reports, 2022-07-28;12(1):12921.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  126. Transcriptome profiling of subepithelial PDGFRalpha cells in colonic mucosa reveals several cell-selective markers
    Authors: SE Ha, B Jin, BG Jorgensen, H Zogg, L Wei, R Singh, C Park, M Kurahashi, S Kim, G Baek, SM Poudrier, MY Lee, KM Sanders, S Ro
    PLoS ONE, 2022-05-13;17(5):e0261743.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  127. PDGFRalpha-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms
    Authors: JM Jacob, SE Di Carlo, I Stzepourgi, A Lepelletie, PD Ndiaye, H Varet, R Legendre, E Kornobis, A Benabid, G Nigro, L Peduto
    Cell Stem Cell, 2022-05-05;29(5):856-868.e5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  128. Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination
    Authors: S Ghorbani, E Jelinek, R Jain, B Buehner, C Li, BM Lozinski, S Sarkar, DK Kaushik, Y Dong, TN Wight, S Karimi-Abd, GJ Schenk, EM Strijbis, J Geurts, P Zhang, CC Ling, VW Yong
    Nature Communications, 2022-05-04;13(1):2445.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  129. Maladaptive myelination promotes generalized epilepsy progression
    Authors: JK Knowles, H Xu, C Soane, A Batra, T Saucedo, E Frost, LT Tam, D Fraga, L Ni, K Villar, S Talmi, JR Huguenard, M Monje
    Nature Neuroscience, 2022-05-02;25(5):596-606.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  130. An estrogen-sensitive fibroblast population drives abdominal muscle fibrosis in an inguinal hernia mouse model
    Authors: T Potluri, MJ Taylor, JJ Stulberg, RL Lieber, H Zhao, SE Bulun
    JCI Insight, 2022-04-19;7(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  131. Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation
    Authors: S Pantasis, J Friemel, SM Brütsch, Z Hu, S Krautbauer, G Liebisch, J Dengjel, A Weber, S Werner, MR Bordoli
    Journal of Cell Science, 2022-04-12;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  132. Platelet-Derived PDGFB Promotes Recruitment of Cancer-Associated Fibroblasts, Deposition of Extracellular Matrix and Tgfbeta Signaling in the Tumor Microenvironment
    Authors: Y Zhang, E Manouchehr, M Herre, J Cedervall, Q Qiao, Z Miao, A Hamidi, L Hellman, M Kamali-Mog, AK Olsson
    Cancers, 2022-04-12;14(8):.
    Species: Mouse
    Sample Types: Whole Cells
  133. Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing
    Authors: XR Ma, X Zhu, Y Xiao, HM Gu, SS Zheng, L Li, F Wang, ZJ Dong, DX Wang, Y Wu, C Yang, W Jiang, K Yao, Y Yin, Y Zhang, C Peng, L Gao, Z Meng, Z Hu, C Liu, L Li, HZ Chen, Y Shu, Z Ju, JW Zhao
    Nature Communications, 2022-03-09;13(1):1225.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IF
  134. Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain
    Authors: A Fernández-, P Lu, AC Geraghty, E Song, MH Lee, J Wood, B Yalç?n, KR Taylor, S Dutton, L Acosta-Alv, L Ni, D Contreras-, JR Gehlhausen, J Klein, C Lucas, T Mao, J Silva, MA Peña-Herná, A Tabachniko, T Takahashi, L Tabacof, J Tosto-Manc, E Breyman, A Kontorovic, D McCarthy, M Quezado, M Hefti, D Perl, R Folkerth, D Putrino, A Nath, A Iwasaki, M Monje
    bioRxiv : the preprint server for biology, 2022-01-10;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  135. Involvement of PAR2 in platelet-derived growth factor receptor-alpha-positive cell proliferation in the colon of diabetic mice
    Authors: YJ Li, JP Ao, X Huang, HL Lu, HY Fu, NN Song, WX Xu, J Chen
    Physiological Reports, 2021-11-01;9(21):e15099.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  136. Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling
    Authors: V Reyes Nico, JM Allaire, AB Alfonso, D Pupo Gómez, V Pomerleau, V Giroux, F Boudreau, N Perreault
    Cells, 2021-10-29;10(11):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  137. Regulation of intestinal immunity and tissue repair by enteric glia
    Authors: F Progatzky, M Shapiro, SH Chng, B Garcia-Cas, CH Classon, S Sevgi, A Laddach, AC Bon-Frauch, R Lasrado, M Rahim, EM Amaniti, S Boeing, K Shah, LJ Entwistle, A Suárez-Bon, MS Wilson, B Stockinger, V Pachnis
    Nature, 2021-10-20;599(7883):125-130.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  138. Spatial gene expression maps of the intestinal lymphoid follicle and associated epithelium identify zonated expression programs
    Authors: N Cohen, H Massalha, S Ben-Moshe, A Egozi, M Rozenberg, K Bahar Halp, S Itzkovitz
    PloS Biology, 2021-10-11;19(10):e3001214.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IF
  139. PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination
    Authors: Y Wang, Y Zhang, S Zhang, B Kim, VL Hull, J Xu, P Prabhu, M Gregory, V Martinez-C, X Zhan, W Deng, F Guo
    Cell Reports, 2021-10-05;37(1):109695.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  140. NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety
    Authors: X Zhang, Y Liu, X Hong, X Li, CK Meshul, C Moore, Y Yang, Y Han, WG Li, X Qi, H Lou, S Duan, TL Xu, X Tong
    Nature Communications, 2021-09-30;12(1):5740.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  141. Sensitive timing of undifferentiation in oligodendrocyte progenitor cells and their enhanced maturation in primary visual cortex of binocularly enucleated mice
    Authors: H Shin, HD Kawai
    PLoS ONE, 2021-09-17;16(9):e0257395.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  142. Microglial ASD-related genes are involved in oligodendrocyte differentiation
    Authors: Y Takanezawa, S Tanabe, D Kato, R Ozeki, M Komoda, T Suzuki, H Baba, R Muramatsu
    Scientific Reports, 2021-09-08;11(1):17825.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  143. Molecular and functional characterization of detrusor PDGFRalpha positive cells in spinal cord injury-induced detrusor overactivity
    Authors: K Lee, SO Park, PC Choi, SB Ryoo, H Lee, LE Peri, T Zhou, RD Corrigan, AC Yanez, SB Moon, BA Perrino, KM Sanders, SD Koh
    Scientific Reports, 2021-08-11;11(1):16268.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  144. Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation
    Authors: L Cordero-Es, AM Dowbaj, TN Kohler, B Strauss, O Sarlidou, G Belenguer, C Pacini, NP Martins, R Dobie, JR Wilson-Kan, R Butler, N Prior, P Serup, F Jug, NC Henderson, F Hollfelder, M Huch
    Cell Stem Cell, 2021-08-02;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  145. Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages
    Authors: I De, V Maklakova, S Litscher, MM Boyd, LC Klemm, Z Wang, C Kendziorsk, LS Collier
    Journal of Neuroinflammation, 2021-07-19;18(1):162.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  146. Regional specialization and fate specification of bone stromal cells in skeletal development
    Authors: KK Sivaraj, HW Jeong, B Dharmaling, D Zeuschner, S Adams, M Potente, RH Adams
    Cell Reports, 2021-07-13;36(2):109352.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  147. Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality
    Authors: SC Schüler, JM Kirkpatric, M Schmidt, D Santinha, P Koch, S Di Sanzo, E Cirri, M Hemberg, A Ori, J von Maltza
    Cell Reports, 2021-06-08;35(10):109223.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  148. Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle
    Authors: A Waisman, AM Norris, M Elías Cost, D Kopinke
    Scientific Reports, 2021-06-03;11(1):11793.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  149. NF1 mutation drives neuronal�activity-dependent initiation of optic glioma
    Authors: Y Pan, JD Hysinger, T Barron, NF Schindler, O Cobb, X Guo, B Yalç?n, C Anastasaki, SB Mulinyawe, A Ponnuswami, S Scheaffer, Y Ma, KC Chang, X Xia, JA Toonen, JJ Lennon, EM Gibson, JR Huguenard, LM Liau, JL Goldberg, M Monje, DH Gutmann
    Nature, 2021-05-26;594(7862):277-282.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  150. The Impact of Fixation on the Detection of Oligodendrocyte Precursor Cell Morphology and Vascular Associations
    Authors: F Pfeiffer, A Sherafat, A Nishiyama
    Cells, 2021-05-24;10(6):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  151. PDGF-PDGFR network differentially regulates the fate, migration, proliferation, and cell cycle progression of myogenic cells
    Authors: O Contreras, A Córdova-Ca, E Brandan
    Cellular Signalling, 2021-05-08;84(0):110036.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC/IF, Western Blot
  152. Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells
    Authors: MN Wosczyna, EE Perez Carb, MW Wagner, S Paredes, CT Konishi, L Liu, TT Wang, RA Walsh, Q Gan, CS Morrissey, TA Rando
    Cell Stem Cell, 2021-05-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Flow Cytometry, IHC
  153. Contribution of PDGFR&alpha-positive cells in maintenance and injury responses in mouse large vessels
    Authors: K Kimura, K Ramirez, TAV Nguyen, Y Yamashiro, A Sada, H Yanagisawa
    Scientific Reports, 2021-04-21;11(1):8683.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  154. Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
    Authors: W Mu, S Li, J Xu, X Guo, H Wu, Z Chen, L Qiao, G Helfer, F Lu, C Liu, QF Wu
    Nature Communications, 2021-04-16;12(1):2288.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  155. Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy
    Authors: L Mészáros, MJ Riemenschn, H Gassner, F Marxreiter, S von Hörste, A Hoffmann, J Winkler
    Acta neuropathologica communications, 2021-04-14;9(1):68.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  156. Identification of PDGFR&alpha-positive interstitial cells in the distal segment of the murine vas deferens
    Authors: T Hiroshige, KI Uemura, S Hirashima, K Hino, A Togo, K Ohta, T Igawa, KI Nakamura
    Scientific Reports, 2021-04-06;11(1):7553.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  157. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence
    Authors: S Choi, B Zhang, S Ma, M Gonzalez-C, D Stein, X Jin, ST Kim, YL Kang, A Besnard, A Rezza, L Grisanti, JD Buenrostro, M Rendl, M Nahrendorf, A Sahay, YC Hsu
    Nature, 2021-03-31;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  158. PDGFR&alpha: Expression and Function during Mitral Valve Morphogenesis
    Authors: K Moore, D Fulmer, L Guo, N Koren, J Glover, R Moore, C Gensemer, T Beck, J Morningsta, R Stairley, RA Norris
    Journal of cardiovascular development and disease, 2021-03-13;8(3):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  159. Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis
    Authors: D Yamakawa, D Katoh, K Kasahara, T Shiromizu, M Matsuyama, C Matsuda, Y Maeno, M Watanabe, Y Nishimura, M Inagaki
    Cell Reports, 2021-03-09;34(10):108817.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  160. Direct reprogramming of oligodendrocyte precursor cells into GABAergic inhibitory neurons by a single homeodomain transcription factor Dlx2
    Authors: LL Boshans, H Soh, WM Wood, TM Nolan, II Mandoiu, Y Yanagawa, AV Tzingounis, A Nishiyama
    Scientific Reports, 2021-02-11;11(1):3552.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  161. SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors
    Authors: G Giuliani, S Vumbaca, C Fuoco, C Gargioli, E Giorda, G Massacci, A Palma, A Reggio, F Riccio, M Rosina, M Vinci, L Castagnoli, G Cesareni
    Cell Death & Disease, 2021-01-25;12(1):122.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  162. Periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain
    Authors: CL Cullen, RE Pepper, MT Clutterbuc, KA Pitman, V Oorschot, L Auderset, AD Tang, G Ramm, B Emery, J Rodger, RB Jolivet, KM Young
    Cell Reports, 2021-01-19;34(3):108641.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  163. Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis
    Authors: MD Brügger, T Valenta, H Fazilaty, G Hausmann, K Basler
    PloS Biology, 2020-12-11;18(12):e3001032.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  164. Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
    Authors: EM Floriddia, T Lourenço, S Zhang, D van Brugge, MM Hilscher, P Kukanja, JP Gonçalves, M Alt?nkök, C Yokota, E Llorens-Bo, SB Mulinyawe, M Grãos, LO Sun, J Frisén, M Nilsson, G Castelo-Br
    Nat Commun, 2020-11-17;11(1):5860.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  165. Neuronal activity-dependent myelin repair promotes motor function recovery after contusion spinal cord injury
    Authors: M Luo, Y Yin, D Li, W Tang, Y Liu, L Pan, L Yu, B Tan
    Brain Res Bull, 2020-11-14;166(0):73-81.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  166. Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin
    Authors: D Jiang, S Christ, D Correa-Gal, P Ramesh, S Kalgudde G, J Wannemache, CH Mayr, V Lupperger, Q Yu, H Ye, M Mück-Häusl, V Rajendran, L Wan, J Liu, U Mirastschi, T Volz, C Marr, HB Schiller, Y Rinkevich
    Nat Commun, 2020-11-06;11(1):5653.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  167. PDGFRA in vascular adventitial MSCs promotes neointima formation in arteriovenous fistula in chronic kidney disease
    Authors: K Song, Y Qing, Q Guo, EK Peden, C Chen, WE Mitch, L Truong, J Cheng
    JCI Insight, 2020-11-05;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells, Whole Tissue
    Applications: ICC, IHC, Western Blot
  168. Retinoic acid signalling in fibro/adipogenic progenitors robustly enhances muscle regeneration
    Authors: L Zhao, JS Son, B Wang, Q Tian, Y Chen, X Liu, JM de Avila, MJ Zhu, M Du
    EBioMedicine, 2020-09-24;60(0):103020.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  169. Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi
    Authors: SP Hong, MJ Yang, H Cho, I Park, H Bae, K Choe, SH Suh, RH Adams, K Alitalo, D Lim, GY Koh
    Nat Commun, 2020-08-14;11(1):4102.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  170. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing
    Authors: S Abbasi, S Sinha, E Labit, NL Rosin, G Yoon, W Rahmani, A Jaffer, N Sharma, A Hagner, P Shah, R Arora, J Yoon, A Islam, A Uchida, CK Chang, JA Stratton, RW Scott, FMV Rossi, TM Underhill, J Biernaskie
    Cell Stem Cell, 2020-08-04;27(3):396-412.e6.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  171. Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases
    Authors: AF Asega, MC Menezes, D Trevisan-S, D Cajado-Car, L Bertholim, AK Oliveira, A Zelanis, SMT Serrano
    Sci Rep, 2020-07-31;10(1):12912.
    Species: Mouse
    Sample Types: Cell Lysates, Tissue Homogenates
    Applications: Western Blot
  172. BCAS1-positive immature oligodendrocytes are affected by the &alpha-synuclein-induced pathology of multiple system atrophy
    Authors: S Kaji, T Maki, J Ueda, T Ishimoto, Y Inoue, K Yasuda, M Sawamura, R Hikawa, T Ayaki, H Yamakado, R Takahashi
    Acta Neuropathol Commun, 2020-07-29;8(1):120.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  173. The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination
    Authors: A Pu, MK Mishra, Y Dong, S Ghorbaniga, EL Stephenson, KS Rawji, C Silva, H Kitagawa, S Sawcer, VW Yong
    J Neuroinflammation, 2020-07-23;17(1):220.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  174. TGF-beta-driven downregulation of the transcription factor TCF7L2 affects Wnt/beta-catenin signaling in PDGFRalpha+ fibroblasts
    Authors: O Contreras, H Soliman, M Theret, FMV Rossi, E Brandan
    J. Cell. Sci., 2020-06-19;133(12):.
    Species: Mouse, Transgenic Mouse
    Sample Types: Cell Lysates, Tissue Homogenates
    Applications: Western Blot
  175. Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth
    Authors: S Davidson, M Efremova, A Riedel, B Mahata, J Pramanik, J Huuhtanen, G Kar, R Vento-Torm, T Hagai, X Chen, MA Haniffa, JD Shields, SA Teichmann
    Cell Rep, 2020-05-19;31(7):107628.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Flow Cytometry
  176. Embryonic microglia influence developing hypothalamic glial populations
    Authors: CM Marsters, D Nesan, R Far, N Klenin, QJ Pittman, DM Kurrasch
    J Neuroinflammation, 2020-05-06;17(1):146.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  177. Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates
    Authors: N Micali, SK Kim, M Diaz-Busta, G Stein-O'Br, S Seo, JH Shin, BG Rash, S Ma, Y Wang, NA Olivares, JI Arellano, KR Maynard, EJ Fertig, AJ Cross, RW Bürli, NJ Brandon, DR Weinberger, JG Chenoweth, DJ Hoeppner, N Sestan, P Rakic, C Colantuoni, RD McKay
    Cell Rep, 2020-05-05;31(5):107599.
    Species: Human
    Sample Types:
    Applications: IF
  178. Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles
    Authors: J Camps, N Breuls, A Sifrim, N Giarratana, M Corvelyn, L Danti, H Grosemans, S Vanuytven, I Thiry, M Belicchi, M Meregalli, K Platko, ME MacDonald, RC Austin, R Gijsbers, G Cossu, Y Torrente, T Voet, M Sampaolesi
    Cell Rep, 2020-05-05;31(5):107597.
    Species: Human
    Sample Types: Whole Cells
  179. Lgr5+�telocytes are a signaling source at the intestinal villus tip
    Authors: K Bahar Halp, H Massalha, RK Zwick, AE Moor, D Castillo-A, M Rozenberg, L Farack, A Egozi, DR Miller, I Averbukh, Y Harnik, N Weinberg-C, FJ de Sauvage, I Amit, OD Klein, M Shoshkes-C, S Itzkovitz
    Nat Commun, 2020-04-22;11(1):1936.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  180. Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient
    Authors: N McCarthy, E Manieri, EE Storm, A Saadatpour, AM Luoma, VN Kapoor, S Madha, LT Gaynor, C Cox, S Keerthivas, K Wucherpfen, GC Yuan, FJ de Sauvage, SJ Turley, RA Shivdasani
    Cell Stem Cell, 2020-02-20;0(0):.
    Species: Mouse
    Sample Types: Tissue
    Applications: IHC
  181. TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung
    Authors: I Wojahn, TH Lüdtke, VM Christoffe, MO Trowe, A Kispert
    Respir. Res., 2019-12-23;20(1):292.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  182. TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation
    Authors: A Grund, M Szaroszyk, M Korf-Kling, M Malek Moha, FA Trogisch, U Schrameck, A Gigina, C Tiedje, M Gaestel, T Kraft, J Hegermann, S Batkai, T Thum, A Perrot, CD Remedios, E Riechert, M Völkers, S Doroudgar, A Jungmann, R Bauer, X Yin, M Mayr, KC Wollert, A Pich, H Xiao, HA Katus, J Bauersachs, OJ Müller, J Heineke
    EMBO Mol Med, 2019-08-30;0(0):e10018.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  183. Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice
    Authors: X Zhang, X Wang, H Yin, L Zhang, A Feng, QX Zhang, Y Lin, B Bao, LL Hernandez, GP Shi, J Liu
    Cell Rep, 2019-07-16;28(3):792-803.e4.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  184. Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
    Authors: SS Welc, I Flores, M Wehling-He, J Ramos, Y Wang, C Bertoni, JG Tidball
    Nat Commun, 2019-06-26;10(1):2788.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  185. Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B
    Authors: MW Hogarth, A Defour, C Lazarski, E Gallardo, JD Manera, TA Partridge, K Nagaraju, JK Jaiswal
    Nat Commun, 2019-06-03;10(1):2430.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  186. Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle
    Authors: MN Wosczyna, CT Konishi, EE Perez Carb, TT Wang, RA Walsh, Q Gan, MW Wagner, TA Rando
    Cell Rep, 2019-05-14;27(7):2029-2035.e5.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC frozen fixed
  187. In Situ Modification of Tissue Stem and Progenitor Cell Genomes
    Authors: JM Goldstein, M Tabebordba, K Zhu, LD Wang, KA Messemer, B Peacker, S Ashrafi Ka, M Gonzalez-C, Y Shwartz, JKW Cheng, R Xiao, T Barungi, C Albright, YC Hsu, LH Vandenberg, AJ Wagers
    Cell Rep, 2019-04-23;27(4):1254-1264.e7.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  188. Myelin repair stimulated by CNS-selective thyroid hormone action
    Authors: MD Hartley, T Banerji, IJ Tagge, LL Kirkemo, P Chaudhary, E Calkins, D Galipeau, MD Shokat, MJ DeBell, S Van Leuven, H Miller, G Marracci, E Pocius, T Banerji, SJ Ferrara, JM Meinig, B Emery, D Bourdette, TS Scanlan
    JCI Insight, 2019-04-18;4(8):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  189. PDGFR?+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland
    Authors: PA Joshi, PD Waterhouse, K Kasaian, H Fang, O Gulyaeva, HS Sul, PC Boutros, R Khokha
    Nat Commun, 2019-04-15;10(1):1760.
    Species: Mouse
    Sample Types: Whole Tissues
    Applications: IHC
  190. Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration
    Authors: X Han, Y Wang, W Pu, X Huang, L Qiu, Y Li, W Yu, H Zhao, X Liu, L He, L Zhang, Y Ji, J Lu, KO Lui, B Zhou
    Stem Cell Reports, 2019-02-14;12(3):624-638.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  191. Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds
    Authors: CF Guerrero-J, PH Dedhia, S Jin, R Ruiz-Vega, D Ma, Y Liu, K Yamaga, O Shestova, DL Gay, Z Yang, K Kessenbroc, Q Nie, WS Pear, G Cotsarelis, MV Plikus
    Nat Commun, 2019-02-08;10(1):650.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  192. Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors
    Authors: L Lukjanenko, S Karaz, P Stuelsatz, U Gurriaran-, J Michaud, G Dammone, F Sizzano, O Mashinchia, S Ancel, E Migliavacc, S Liot, G Jacot, S Metairon, F Raymond, P Descombes, A Palini, B Chazaud, MA Rudnicki, CF Bentzinger, JN Feige
    Cell Stem Cell, 2019-01-24;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  193. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
    Authors: D Aran, AP Looney, L Liu, E Wu, V Fong, A Hsu, S Chak, RP Naikawadi, PJ Wolters, AR Abate, AJ Butte, M Bhattachar
    Nat. Immunol., 2019-01-14;20(2):163-172.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  194. Profiling proliferative cells and their progeny in damaged murine hearts
    Authors: K Kretzschma, Y Post, M Bannier-Hé, A Mattiotti, J Drost, O Basak, VSW Li, M van den Bo, QD Gunst, D Versteeg, L Kooijman, S van der El, JH van Es, E van Rooij, MJB van den Ho, H Clevers
    Proc. Natl. Acad. Sci. U.S.A., 2018-12-07;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr, IHC-P
  195. Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome
    Authors: S Oishi, D Harkins, ND Kurniawan, M Kasherman, L Harris, O Zalucki, RM Gronostajs, THJ Burne, M Piper
    EBioMedicine, 2018-11-29;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  196. Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration
    Authors: MJ Carr, JS Toma, APW Johnston, PE Steadman, SA Yuzwa, N Mahmud, PW Frankland, DR Kaplan, FD Miller
    Cell Stem Cell, 2018-11-29;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  197. AMPK Activation Regulates LTBP4-Dependent TGF-?1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy
    Authors: G Juban, M Saclier, H Yacoub-You, A Kernou, L Arnold, C Boisson, S Ben Larbi, M Magnan, S Cuvellier, M Théret, BJ Petrof, I Desguerre, J Gondin, R Mounier, B Chazaud
    Cell Rep, 2018-11-20;25(8):2163-2176.e6.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  198. Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1?
    Authors: SK Jensen, NJ Michaels, S Ilyntskyy, MB Keough, O Kovalchuk, VW Yong
    Cell Rep, 2018-09-18;24(12):3167-3179.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  199. Pulmonary pericytes regulate lung morphogenesis
    Authors: K Kato, R Diéguez-Hu, DY Park, SP Hong, S Kato-Azuma, S Adams, M Stehling, B Trappmann, JL Wrana, GY Koh, RH Adams
    Nat Commun, 2018-06-22;9(1):2448.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  200. Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
    Authors: SN Kim, S Akindehin, HJ Kwon, YH Son, A Saha, YS Jung, JK Seong, KM Lim, JH Sung, KR Maddipati, YH Lee
    Sci Rep, 2018-06-11;8(1):8856.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  201. Perfect chronic skeletal muscle regeneration in adult spiny mice, Acomys cahirinus
    Authors: M Maden, JO Brant, A Rubiano, AGW Sandoval, C Simmons, R Mitchell, H Collin-Hoo, J Jacobson, S Omairi, K Patel
    Sci Rep, 2018-06-11;8(1):8920.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  202. Myelination of the developing lateral olfactory tract and anterior commissure
    Authors: LN Collins, DL Hill, PC Brunjes
    J. Comp. Neurol., 2018-04-26;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  203. B-1a lymphocytes promote oligodendrogenesis during brain development
    Authors: S Tanabe, T Yamashita
    Nat. Neurosci., 2018-03-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  204. Role of P2XReceptor in Mouse Voiding Function
    Authors: W Yu, WG Hill, SC Robson, ML Zeidel
    Sci Rep, 2018-01-30;8(1):1838.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  205. Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner
    Authors: S Mitew, I Gobius, LR Fenlon, SJ McDougall, D Hawkes, YL Xing, H Bujalka, AL Gundlach, LJ Richards, TJ Kilpatrick, TD Merson, B Emery
    Nat Commun, 2018-01-22;9(1):306.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  206. Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion
    Authors: S Begolly, JA Olschowka, T Love, JP Williams, MK O'Banion
    Glia, 2017-12-30;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  207. Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination
    Authors: Y Chen, W Zhen, T Guo, Y Zhao, A Liu, JP Rubio, D Krull, JC Richardson, H Lu, R Wang
    PLoS ONE, 2017-12-18;12(12):e0189380.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  208. Colonic PDGFR? Overexpression Accompanied Forkhead Transcription Factor FOXO3 Up-Regulation in STZ-Induced Diabetic Mice
    Authors: H Lu, C Zhang, N Song, C Lu, L Tong, X Huang, YC Kim, J Chen, W Xu
    Cell. Physiol. Biochem., 2017-08-28;43(1):158-171.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  209. Transcriptome analysis of PDGFR?+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFR?+ cell hyperplasia
    Authors: SE Ha, MY Lee, M Kurahashi, L Wei, BG Jorgensen, C Park, PJ Park, D Redelman, KC Sasse, LS Becker, KM Sanders, S Ro
    PLoS ONE, 2017-08-14;12(8):e0182265.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  210. Pdgfr? functions in endothelial-derived cells to regulate neural crest cells and development of the great arteries
    Authors: H Aghajanian, YK Cho, NW Rizer, Q Wang, L Li, K Degenhardt, R Jain
    Dis Model Mech, 2017-07-14;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  211. ALS skeletal muscle shows enhanced TGF-? signaling, fibrosis and induction of fibro/adipogenic progenitor markers
    Authors: D Gonzalez, O Contreras, DL Rebolledo, JP Espinoza, B van Zunder, E Brandan
    PLoS ONE, 2017-05-16;12(5):e0177649.
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  212. Physiologically activated mammary fibroblasts promote postpartum mammary cancer
    Authors: Q Guo, J Minnier, J Burchard, K Chiotti, P Spellman, P Schedin
    JCI Insight, 2017-03-23;2(6):e89206.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  213. Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In�Vivo
    Authors: N Guimar?es-, P Cattaneo, Y Sun, T Moore-Morr, Y Gu, ND Dalton, E Rockenstei, E Masliah, KL Peterson, WB Stallcup, J Chen, SM Evans
    Cell Stem Cell, 2017-01-19;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  214. Leptin sustains spontaneous remyelination in the adult central nervous system
    Authors: K Matoba, R Muramatsu, T Yamashita
    Sci Rep, 2017-01-16;7(0):40397.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  215. Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos
    Sci Rep, 2016-12-19;6(0):39457.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  216. Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation
    Cell Rep, 2016-11-22;17(9):2312-2325.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  217. Real-time and Non-invasive Monitoring of Embryonic Stem Cell Survival during the Development of Embryoid Bodies with Smart Nanosensor
    Authors: Dong-An Wang
    Acta Biomater, 2016-11-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  218. USP9X deletion elevates the density of oligodendrocytes within the postnatal dentate gyrus
    Authors: Michael Piper
    Neurogenesis (Austin), 2016-09-30;3(1):e1235524.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  219. Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development
    Authors: K Noda, M Kitami, K Kitami, M Kaku, Y Komatsu
    Proc Natl Acad Sci USA, 2016-04-26;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells
    Applications: IHC, Western Blot
  220. Spatio-Temporal Patterns of Demyelination and Remyelination in the Cuprizone Mouse Model
    Authors: I Tagge, A O'Connor, P Chaudhary, J Pollaro, Y Berlow, M Chalupsky, D Bourdette, R Woltjer, M Johnson, W Rooney
    PLoS ONE, 2016-04-07;11(4):e0152480.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  221. AHNAK deficiency promotes browning and lipolysis in mice via increased responsiveness to ?-adrenergic signalling
    Authors: JH Shin, SH Lee, YN Kim, IY Kim, YJ Kim, DS Kyeong, HJ Lim, SY Cho, J Choi, YJ Wi, JH Choi, YS Yoon, YS Bae, JK Seong
    Sci Rep, 2016-03-18;6(0):23426.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  222. Double minute amplification of mutant PDGF receptor alpha in a mouse glioma model.
    Authors: Zou H, Feng R, Huang Y, Tripodi J, Najfeld V, Tsankova N, Jahanshahi M, Olson L, Soriano P, Friedel R
    Sci Rep, 2015-02-16;5(0):8468.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  223. Transplanted bone marrow-derived circulating PDGFRalpha+ cells restore type VII collagen in recessive dystrophic epidermolysis bullosa mouse skin graft.
    Authors: Iinuma S, Aikawa E, Tamai K, Fujita R, Kikuchi Y, Chino T, Kikuta J, McGrath J, Uitto J, Ishii M, Iizuka H, Kaneda Y
    J Immunol, 2015-01-19;194(4):1996-2003.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  224. Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development.
    Authors: Daquinag, A C, Tseng, C, Salameh, A, Zhang, Y, Amaya-Manzanares, F, Dadbin, A, Florez, F, Xu, Y, Tong, Q, Kolonin, M G
    Cell Death Differ, 2014-10-24;22(2):351-63.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  225. Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling.
    Authors: Pinto, Mauricio, Dye, Wendy W, Jacobsen, Britta M, Horwitz, Kathryn
    BMC Cancer, 2014-10-01;14(0):735.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  226. Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells.
    Authors: Ettle B, Reiprich S, Deusser J, Schlachetzki J, Xiang W, Prots I, Masliah E, Winner B, Wegner M, Winkler J
    Mol Cell Neurosci, 2014-07-11;62(0):68-78.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC, Western Blot
  227. Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.
    Authors: Moore-Morris T, Guimaraes-Camboa N, Banerjee I, Zambon A, Kisseleva T, Velayoudon A, Stallcup W, Gu Y, Dalton N, Cedenilla M, Gomez-Amaro R, Zhou B, Brenner D, Peterson K, Chen J, Evans S
    J Clin Invest, 2014-06-17;124(7):2921-34.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  228. Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.
    Authors: Gibson, Erin M, Purger, David, Mount, Christop, Goldstein, Andrea K, Lin, Grant L, Wood, Lauren S, Inema, Ingrid, Miller, Sarah E, Bieri, Gregor, Zuchero, J Bradle, Barres, Ben A, Woo, Pamelyn, Vogel, Hannes, Monje, Michelle
    Science, 2014-04-10;344(6183):1252304.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  229. Nitric oxide controls fat deposition in dystrophic skeletal muscle by regulating fibro-adipogenic precursor differentiation.
    Authors: Cordani N, Pisa V, Pozzi L, Sciorati C, Clementi E
    Stem Cells, 2014-04-01;32(4):874-85.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  230. Hypoxia inducible factor-2alpha regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitors.
    Authors: Duan L, Takeda K, Fong G
    PLoS ONE, 2014-01-27;9(1):e84736.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  231. Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
    Authors: Fan J, Ponferrada V, Sato T, Vemaraju S, Fruttiger M, Gerhardt H, Ferrara N, Lang R
    Development, 2013-12-18;141(2):448-59.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  232. Distinct fibroblast lineages determine dermal architecture in skin development and repair.
    Authors: Driskell R, Lichtenberger B, Hoste E, Kretzschmar K, Simons B, Charalambous M, Ferron S, Herault Y, Pavlovic G, Ferguson-Smith A, Watt F
    Nature, 2013-12-12;504(7479):277-81.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  233. Abnormal development of NG2+PDGFR-alpha+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model.
    Authors: Carter C, Vogel T, Zhang Q, Seo S, Swiderski R, Moninger T, Cassell M, Thedens D, Keppler-Noreuil K, Nopoulos P, Nishimura D, Searby C, Bugge K, Sheffield V
    Nat Med, 2012-11-18;18(12):1797-804.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Immunoprecipitation, Western Blot
  234. Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation.
    Authors: Tang Z, Arjunan P, Lee C, Li Y, Kumar A, Hou X, Wang B, Wardega P, Zhang F, Dong L, Zhang Y, Zhang SZ, Ding H, Fariss RN, Becker KG, Lennartsson J, Nagai N, Cao Y, Li X
    J. Exp. Med., 2010-03-15;207(4):867-80.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  235. Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke.
    Authors: Su EJ, Fredriksson L, Geyer M, Folestad E, Cale J, Andrae J, Gao Y, Pietras K, Mann K, Yepes M, Strickland DK, Betsholtz C, Eriksson U, Lawrence DA
    Nat. Med., 2008-06-22;14(7):731-7.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  236. Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis.
    Authors: Makar TK, Trisler D, Bever CT, Goolsby JE, Sura KT, Balasubramanian S, Sultana S, Patel N, Ford D, Singh IS, Gupta A, Valenzuela RM, Dhib-Jalbut S
    J. Neuroimmunol., 2008-05-08;196(1):67-81.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  237. Oligodendroglial metabotropic glutamate receptors are developmentally regulated and involved in the prevention of apoptosis.
    Authors: Luyt K, Varadi A, Durant CF, Molnar E
    J. Neurochem., 2006-07-06;99(2):641-56.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  238. Tumor-driven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma.
    Authors: Tejada ML, Yu L, Dong J, Jung K, Meng G, Peale FV, Frantz GD, Hall L, Liang X, Gerber HP, Ferrara N
    Clin. Cancer Res., 2006-05-01;12(9):2676-88.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  239. Heterogeneity of murine periosteum progenitors involved in fracture healing
    Authors: Brya G Matthews, Sanja Novak, Francesca V Sbrana, Jessica L Funnell, Ye Cao, Emma J Buckels et al.
    eLife
  240. Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system
    Authors: Rawji KS, Young AMH, Ghosh T et al.
    Acta Neuropathol.
  241. Epidermal beta -catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
    Authors: Beate M. Lichtenberger, Maria Mastrogiannaki, Fiona M. Watt
    Nature Communications
  242. Tcf21 marks visceral adipose mesenchymal progenitors and functions as a rate-limiting factor during visceral adipose tissue development
    Authors: Q Liu, C Li, B Deng, P Gao, L Wang, Y Li, M Shiri, F Alkaifi, J Zhao, JM Stephens, CA Simintiras, J Francis, J Sun, X Fu
    Cell Reports, 2023-02-28;42(3):112166.
  243. High-efficiency pharmacogenetic ablation of oligodendrocyte progenitor cells in the adult mouse CNS
    Authors: Yao Lulu Xing, Jasmine Poh, Bernard H.A. Chuang, Kaveh Moradi, Stanislaw Mitew, William D. Richardson et al.
    Cell Reports Methods
  244. p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression
    Authors: PP Gonzalez, J Kim, RP Galvao, N Cruickshan, R Abounader, H Zong
    Glia, 2018-02-02;0(0):.
  245. Hypertrophic chondrocytes serve as a reservoir for marrow-associated skeletal stem and progenitor cells, osteoblasts, and adipocytes during skeletal development
    Authors: Jason T Long, Abigail Leinroth, Yihan Liao, Yinshi Ren, Anthony J Mirando, Tuyet Nguyen et al.
    eLife
  246. MBNL1 drives dynamic transitions between fibroblasts and myofibroblasts in cardiac wound healing
    Authors: D Bugg, LRJ Bailey, RC Bretherton, KE Beach, IM Reichardt, KZ Robeson, AC Reese, J Gunaje, G Flint, CA DeForest, A Stempien-O, J Davis
    Cell Stem Cell, 2022-02-16;29(3):419-433.e10.
  247. Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination
    Authors: L Pan, A Trimarco, AJ Zhang, K Fujimori, Y Urade, LO Sun, C Taveggia, Y Zhang
    Elife, 2023-02-13;12(0):.
  248. AMP‐activated protein kinase inhibition in fibro‐adipogenic progenitors impairs muscle regeneration and increases fibrosis
    Authors: Xiangdong Liu, Liang Zhao, Yao Gao, Yanting Chen, Qiyu Tian, Jun Seok Son et al.
    Journal of Cachexia, Sarcopenia and Muscle
  249. The active contribution of OPCs to neuroinflammation is mediated by LRP1
    Authors: Anthony Fernández-Castañeda, Megan S. Chappell, Dorian A Rosen, Scott M. Seki, Rebecca M. Beiter, David M. Johanson et al.
    Acta Neuropathologica
  250. PRC2 Is Dispensable in Vivo for beta -Catenin-Mediated Repression of Chondrogenesis in the Mouse Embryonic Cranial Mesenchyme
    Authors: James Ferguson, Mahima Devarajan, Gregg DiNuoscio, Alina Saiakhova, Chia-Feng Liu, Veronique Lefebvre et al.
    G3 Genes|Genomes|Genetics
  251. Exercise rather than fluoxetine promotes oligodendrocyte differentiation and myelination in the hippocampus in a male mouse model of depression
    Authors: Jing Tang, Xin Liang, Xiaoyun Dou, Yingqiang Qi, Chunmao Yang, Yanmin Luo et al.
    Translational Psychiatry
  252. Kaposi's sarcoma herpesvirus activates the hypoxia response to usurp HIF2alpha-dependent translation initiation for replication and oncogenesis
    Authors: O Méndez-Sol, M Bendjennat, J Naipauer, PR Theodoridi, JJD Ho, RE Verdun, JM Hare, E Cesarman, S Lee, EA Mesri
    Cell Reports, 2021-12-28;37(13):110144.
  253. Retinoic Acid Is Required for Oligodendrocyte Precursor Cell Production and Differentiation in the Postnatal Mouse Corpus Callosum
    Authors: Vivianne E. Morrison, Victoria N. Smith, Jeffrey K. Huang
    eNeuro
  254. Role of pericytes in the development of cerebral cavernous malformations
    Authors: Zifeng Dai, Jingwei Li, Ying Li, Rui Wang, Huili Yan, Ziyu Xiong et al.
    iScience
  255. Characterizing Neonatal Heart Maturation, Regeneration, and Scar Resolution Using Spatial Transcriptomics
    Authors: Adwiteeya Misra, Cameron D. Baker, Elizabeth M. Pritchett, Kimberly N. Burgos Villar, John M. Ashton, Eric M. Small
    Journal of Cardiovascular Development and Disease
  256. Generation of iPSC-derived limb progenitor-like cells for stimulating phalange regeneration in the adult mouse
    Authors: Y Chen, H Xu, G Lin
    Cell Discov, 2017-12-19;3(0):17046.
  257. Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2
    Authors: Adam A A Nabeebaccus, Sharwari Verma, Anna Zoccarato, Giulia Emanuelli, Celio XC. Santos, Katrin Streckfuss-Bömeke et al.
    Biochemical and Biophysical Research Communications
  258. Muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury
    Authors: Francesca Boscolo Sesillo, Varsha Rajesh, Michelle Wong, Pamela Duran, John B. Rudell, Courtney P. Rundio et al.
    npj Regenerative Medicine
  259. Monitoring Therapeutic Response to Anti-Fibroblast Activation Protein (FAP) CAR T Cells using [18F]AlF-FAPI-74
    Authors: Iris K. Lee, Estela Noguera-Ortega, Zebin Xiao, Leslie Todd, John Scholler, Decheng Song et al.
    Clinical Cancer Research
  260. Tenotomy-induced muscle atrophy is sex-specific and independent of NF kappa B
    Authors: Gretchen A Meyer, Stavros Thomopoulos, Yousef Abu-Amer, Karen C Shen
    eLife
  261. PDGFRa cells in mouse urinary bladder: A new class of interstitial cells.
    Authors: Koh BH, Roy R, Hollywood MAet al.
    J Cell Mol Med
  262. Mesenchymal VEGFA induces aberrant differentiation in heterotopic ossification
    Authors: Charles Hwang, Simone Marini, Amanda K. Huber, David M. Stepien, Michael Sorkin, Shawn Loder et al.
    Bone Research
  263. Oligodendrocyte lineage is severely affected in human alcohol-exposed foetuses
    Authors: Florent Marguet, Mélanie Brosolo, Gaëlle Friocourt, Fanny Sauvestre, Pascale Marcorelles, Céline Lesueur et al.
    Acta Neuropathologica Communications
  264. Acute minocycline administration reduces brain injury and improves long-term functional outcomes after delayed hypoxemia following traumatic brain injury
    Authors: Marta Celorrio, Kirill Shumilov, Camryn Payne, Sangeetha Vadivelu, Stuart H. Friess
    Acta Neuropathologica Communications
  265. Remodelling of myelinated axons and oligodendrocyte differentiation is stimulated by environmental enrichment in the young adult brain
    Authors: Madeline Nicholson, Rhiannon J. Wood, David G. Gonsalvez, Anthony J. Hannan, Jessica L. Fletcher, Junhua Xiao et al.
    European Journal of Neuroscience
  266. Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis
    Authors: Gesine M. Dittrich, Natali Froese, Xue Wang, Hannah Kroeger, Honghui Wang, Malgorzata Szaroszyk et al.
    Basic Research in Cardiology
  267. Visual deprivation induces transient upregulation of oligodendrocyte progenitor cells in the subcortical white matter of mouse visual cortex
    Authors: Hyeryun Shin, Hideki Derek Kawai
    IBRO Neuroscience Reports
  268. tPA Deficiency in Mice Leads to Rearrangement in the Cerebrovascular Tree and Cerebroventricular Malformations
    Authors: Christina Stefanitsch, Anna-Lisa E. Lawrence, Anna Olverling, Ingrid Nilsson, Linda Fredriksson
    Frontiers in Cellular Neuroscience
  269. In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes
    Authors: Xin Jin, Sean K. Simmons, Amy Guo, Ashwin S. Shetty, Michelle Ko, Lan Nguyen et al.
    Science
  270. Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis
    Authors: Hilgendorf KI, Johnson CT, Mezger A et al.
    Cell
  271. Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing
    Authors: Alerie G. de la Fuente, Rayner M.L. Queiroz, Tanay Ghosh, Christopher E. McMurran, Juan F. Cubillos, Dwight E. Bergles et al.
    Molecular & Cellular Proteomics
  272. Dead muscle tissue promotes dystrophic calcification by lowering circulating TGF-beta 1 level
    Authors: La Li, Shiqi Xiang, Bing Wang, Hang Lin, Guorui Cao, Peter G. Alexander et al.
    Bone & Joint Research
  273. Cilia-Mediated Insulin/Akt and ST2/JNK Signaling Pathways Regulate the Recovery of Muscle Injury
    Authors: Yamakawa D, Tsuboi J, Kasahara K et al.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany)
  274. Intrauterine Growth Restriction and Hyperoxia as a Cause of White Matter Injury
    Authors: Jill L. Chang, Mirrah Bashir, Christiana Santiago, Kathryn Farrow, Camille Fung, Ashley S. Brown et al.
    Developmental Neuroscience
  275. Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Is a Negative Regulator of Oligodendrocyte Progenitor Cell Differentiation in the Adult Mouse Brain
    Authors: Loic Auderset, Kimberley A. Pitman, Carlie L. Cullen, Renee E. Pepper, Bruce V. Taylor, Lisa Foa et al.
    Frontiers in Cell and Developmental Biology
  276. Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division
    Authors: Robert A. Hill, Kiran D. Patel, Christopher M. Goncalves, Jaime Grutzendler, Akiko Nishiyama
    Nature Neuroscience
  277. Aging-Affected MSC Functions and Severity of Periodontal Tissue Destruction in a Ligature-Induced Mouse Periodontitis Model
    Authors: Kyaw Thu Aung, Kentaro Akiyama, Masayoshi Kunitomo, Aung Ye Mun, Ikue Tosa, Ha Thi Thu Nguyen et al.
    International Journal of Molecular Sciences
  278. SYK coordinates neuroprotective microglial responses in neurodegenerative disease
    Authors: Hannah Ennerfelt, Elizabeth L. Frost, Daniel A. Shapiro, Coco Holliday, Kristine E. Zengeler, Gabrielle Voithofer et al.
    Cell
  279. NOX4 inhibition promotes the remodeling of dystrophic muscle
    Authors: David W. Hammers
    JCI Insight
  280. Treatment with Amniotic Fluid Stem Cell Extracellular Vesicles Promotes Fetal Lung Branching and Cell Differentiation at Canalicular and Saccular Stages in Experimental Pulmonary Hypoplasia Secondary to Congenital Diaphragmatic Hernia
    Authors: Kasra Khalaj, Rebeca Lopes Figueira, Lina Antounians, Sree Gandhi, Matthew Wales, Louise Montalva et al.
    Stem Cells Translational Medicine
  281. Nintedanib Reduces Muscle Fibrosis and Improves Muscle Function of the Alpha-Sarcoglycan-Deficient Mice
    Authors: Jorge Alonso-Pérez, Ana Carrasco-Rozas, Maria Borrell-Pages, Esther Fernández-Simón, Patricia Piñol-Jurado, Lina Badimon et al.
    Biomedicines
  282. Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity
    Authors: Christopher W Mount, Belgin Yalçın, Kennedy Cunliffe-Koehler, Shree Sundaresh, Michelle Monje
    eLife
  283. GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis
    Authors: Jing Qin, Arend H. Sikkema, Kristine van der Bij, Jenny C. de Jonge, Karin Klappe, Vera Nies et al.
    The Journal of Neuroscience
  284. The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX
    Authors: Alessia Caramello, Christophe Galichet, Miriam Llorian Sopena, Robin Lovell‐Badge, Karine Rizzoti
    Developmental Neurobiology
  285. Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development
    Authors: Venkata Thulabandu, Timothy Nehila, James W. Ferguson, Radhika P. Atit
    Developmental Biology
  286. A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis
    Authors: Sisu Han, Daniel J. Dennis, Anjali Balakrishnan, Rajiv Dixit, Olivier Britz, Dawn Zinyk et al.
    Development
  287. Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke
    Authors: Enming Joseph Su, Chunzhang Cao, Linda Fredriksson, Ingrid Nilsson, Christina Stefanitsch, Tamara K. Stevenson et al.
    Acta Neuropathologica
  288. Fractionation Spares Mice From Radiation-Induced Reductions in Weight Gain But Does Not Prevent Late Oligodendrocyte Lineage Side Effects
    Authors: Sage Begolly, Peter G. Shrager, John A. Olschowka, Jacqueline P. Williams, M. Kerry O'Banion
    International Journal of Radiation Oncology*Biology*Physics
  289. Tissue-Specific Cell Cycle Indicator Reveals Unexpected Findings for Cardiac Myocyte Proliferation
    Authors: Maretoshi Hirai, Ju Chen, Sylvia M. Evans
    Circulation Research
  290. IFT20 modulates ciliary PDGFR alpha signaling by regulating the stability of Cbl E3 ubiquitin ligases
    Authors: Fabian Marc Schmid, Kenneth Bødtker Schou, Martin Juel Vilhelm, Maria Schrøder Holm, Loretta Breslin, Pietro Farinelli et al.
    Journal of Cell Biology
  291. Comprehensive Expression Analysis of Cardiac Fibroblast Growth Factor 23 in Health and Pressure-induced Cardiac Hypertrophy
    Authors: Fiona Eitner, Beatrice Richter, Saskia Schwänen, Malgorzata Szaroszyk, Isabel Vogt, Andrea Grund et al.
    Frontiers in Cell and Developmental Biology
  292. Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis.
    Authors: Mouton AJ, Ma Y, Rivera Gonzalez OJ et al.
    Basic Res. Cardiol.
  293. Loss of ABCA8B decreases myelination by reducing oligodendrocyte precursor cells in mice
    Authors: Yiran Liu, David Castano, Francesco Girolamo, Laia Trigueros-Motos, Han-Gyu Bae, Suat Peng Neo et al.
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  294. A genetic system for tissue-specific inhibition of cell proliferation
    Authors: Wenjuan Pu, Ximeng Han, Lingjuan He, Yan Li, Xiuzhen Huang, Mingjun Zhang et al.
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  295. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination
    Authors: Huan Xu, Yulia Dzhashiashvili, Ankeeta Shah, Rejani B. Kunjamma, Yi-lan Weng, Benayahu Elbaz et al.
    Neuron
  296. Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice
    Authors: Patrick E. Steadman, Frances Xia, Moriam Ahmed, Andrew J. Mocle, Amber R.A. Penning, Anna C. Geraghty et al.
    Neuron
  297. Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment
    Authors: Erin M. Gibson, Surya Nagaraja, Alfonso Ocampo, Lydia T. Tam, Lauren S. Wood, Praveen N. Pallegar et al.
    Cell
  298. PTP alpha is required for laminin-2-induced Fyn-Akt signaling to drive oligodendrocyte differentiation
    Authors: Philip T. T. Ly, Craig Stewart, Catherine J. Pallen
    Journal of Cell Science

FAQs

  1. Does Mouse PDGF R alpha Antibody, Catalog # AF1062, cross-react with rat PDGF R alpha?

    • We have not tested Catalog # AF1062 against rat samples in-house so we do not guarantee that it will detect rat PDGF R alpha. However, Uniprot indicates the homology between mouse and rat PDGF R to be 95.7%, which suggests cross-reactivity is likely. 

View all Antibody FAQs
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Reviews for Mouse PDGF R alpha Antibody

Average Rating: 4.5 (Based on 12 Reviews)

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Mouse PDGF R alpha Antibody
By Anonymous on 07/14/2023
Application: Immunocytochemistry/Immunofluorescence Sample Tested: fixed mouse brain Species: Mouse

1:100, free-floating

Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 10/20/2022
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Adult pancreas Species: Mouse

Primary goat anti-mouse PDGFRa (1:300) with Donkey anti-goat AF647 (1:500) on adult mouse pancreas. It works well and clearly shows specific staining of fibroblasts.

Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 06/28/2022
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Brain stem tissue Species: Mouse and Mouse Embryo
Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 05/10/2020
Application: WB Sample Tested: Adult heart Species: Mouse

3 mice hearts extractions after MI.
HSP60 was used as loading control.
There is a non specific band around 80 kDa.

Western Blot Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 05/10/2020
Application: Immunocytochemistry/Immunofluorescence Sample Tested: primary cardiac fibroblasts Species: Rat

rat primary cardiac fibroblasts, PDGFRa in red, DAPI in blue

Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 05/10/2020
Application: IHC Sample Tested: Adult heart Species: Mouse

mouse heart post MI, troponin I in green, PDGFRa in red, DAPI in blue

Immunohistochemistry Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 10/20/2019
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Adult brain Species: Mouse

Dilution 1:200

Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Jun Cai on 01/16/2019
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Spinal cord tissue Species: Mouse
Mouse PDGF R alpha Antibody
By Thiruloga Chandru on 07/27/2018
Application: Immunocytochemistry/Immunofluorescence Sample Tested: IPS2 induced pluripotent stem cells Species: Mouse
Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 01/25/2018
Application: WB Sample Tested: IPS2 induced pluripotent stem cells Species: Mouse
Western Blot Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 01/13/2018
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Embryo Species: Mouse

differentiation assay using e12.5 mouse neural stem cells.
PDGFR (red)/ Dapi (blue)

Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 08/10/2017
Application: IHC Sample Tested: Brain (cerebellum) tissue Species: Mouse