PE 22-28
Description: Potent inhibitor of TREK-1 channels
Purity: ≥95%
Biological Activity
PE 22-28 is a potent inhibitor of potassium channel subfamily K member 2/TREK-1 (IC50 = 0.12 nM). In rodent models of ischemia PE 22-28 reduces apoptotic death of β cells, increases hippocampal neurogenesis, and reduces stroke-induced motor and cognitive defects.Technical Data
M.Wt:
773.89
Formula:
C35H55N11O9
Sequence:
GVSWGLR
Solubility:
Soluble to 2 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
1801959-12-5
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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