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K2P2.1 (TREK-1), K2P10.1 (TREK-2) and K2P4.1 (TRAAK) channel activator
Potent K2P2.1 (TREK-1) channel blocker
KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator
K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channel activator
Potent inhibitor of TREK-1 channels