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preQ1-azide

Catalog #: 7833 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7833/10
preQ1-azide | General Laboratory Research Reagent
1 Image
Description: preQ1 with azide handle for click chemistry

Chemical Name: N-[6-[[(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]amino]hexyl]-3-(2-azidoethoxy)propanamide

Purity: ≥95%

Product Details
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Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

preQ1-azide is a modified analog of the natural substrate prequeosine1 (preQ1). It contains an azide handle allowing attachment of additional groups to preQ1 via Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry. preQ1-azide is a toolbox compound for RNA-TAG (transglycosylation at guanosine).

Other RNA-TAG toolbox compounds include preQ1-biotin (Cat. No. 7804) and preQ1- alkyne (Cat. No. 7806)

Plasmids for expression of the E.coli TGT enzyme (#138201) and for cloning an RNA of interest into a vector containing the recognition motif at the 3' end (#138209) are available from Addgene.

Technical Data

M.Wt:
419.49
Formula:
C18H29N9O3
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from The Regents of the University of California.

Product Datasheets

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Reconstitution Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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