LIGHT/TNFSF14: Products
LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.
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Simple Plex Human LIGHT Cartridge
Simple Plex Human LIGHT/TNFSF14 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Human LIGHT/TNFSF14 APC-conjugated Antibody
Clone 115520 was used by HLDA to establish CD designation
Simple Plex Control for Human LIGHT/TNFSF14
Control for use with Human LIGHT/TNFSF14 Simple Plex Cartridge Kit
Human LIGHT/TNFSF14 Alexa Fluor® 488-conjugated Antibody
Clone 115520 was used by HLDA to establish CD designation
Human LIGHT/TNFSF14 Alexa Fluor® 700-conjugated Antibody
Clone 115520 was used by HLDA to establish CD designation
Human LIGHT/TNFSF14 Alexa Fluor® 647-conjugated Antibody
Clone 115520 was used by HLDA to establish CD designation
Human LIGHT/TNFSF14 Alexa Fluor® 750-conjugated Antibody
Clone 115520 was used by HLDA to establish CD designation
Human LIGHT/TNFSF14 Alexa Fluor® 594-conjugated Antibody
Clone 115520 was used by HLDA to establish CD designation
Human LIGHT/TNFSF14 Alexa Fluor® 350-conjugated Antibody
Clone 115520 was used by HLDA to establish CD designation