PARP: Products
PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.
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"PARP" has 6 results in Products.
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HT PARP in vivo Pharmacodynamic ELISA Kit II
For the quantitation of PAR in tissue culture cells and tumor lysates.
Universal Chemiluminescent PARP Assay - Histone Coated Wells
For the in vitro screening of candidate PARP-1 inhibitors
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