"4144-tc" has 22 results in Resources.

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Slits and ROBO receptors are perhaps best known for roles in axon guidance, but they have also been implicated in morphogenesis, tumorigenesis, cell/cell junction regulation, and migration. Slit proteins contain four domains of leucine-rich repeats, seven to nine EGF-like sequences, and a laminin-G domain. In mammals, there are three slit genes, all of which are expressed in the nervous system...

This protocol must be read in its entirety before using Catalog # NSC002 and AR003. Caution: The mouse cortical stem cells used in this protocol contain trace amounts of human transferrin and DMSO, and the media used in this protocol contains trace amounts of transferrin. The transferrin was purified from donor plasma and tested at the donor level using an FDA licensed method and found to be...

This protocol must be read in its entirety before using Catalog # NSC002 and AR003. Caution: The mouse cortical stem cells used in this protocol contain trace amounts of human transferrin and DMSO, and the media used in this protocol contains trace amounts of transferrin. The transferrin was tested at the donor level using an FDA licensed method and found to be non-reactive for anti HIV-1/2 and...

This protocol must be read in its entirety before using Catalog # NSC001. Caution: The rat cortical stem cells used in this protocol contain trace amounts of human transferrin and DMSO, and the media used in this protocol contains trace amounts of transferrin. The transferrin was purified from donor plasma and tested at the donor level using an FDA licensed method and found to be non-reactive for...

Jody L. Bonnevier, Ricardo deMedeiros, Qi Cheng, Molly Thomas, David Galitz, Kristin Coley, Cyrus Munshi, Julio Herrera, Kurt LaBresh, J.P. Houchins & Jessie H.T. Ni ABSTRACT Although IL-17A is made by CD4+ Th17 cells and there is an ever-increasing body of literature on these cells, other cells make IL-17A, including CD8+ (Tc17) and ϒ-δ T cells, NK cells, and neutrophils. There are many...

Media supplements are classical media additives that can improve mammalian cell growth and viability under serum-free or low serum conditions. R&D System manufactures serum-free cell culture media supplements that support commonly-used laboratory cell lines as well as for more specialized cells, such as primary neurons, stem cells, and organoids. All of our supplements are produced, validated,...

If culturing in the absence of a feeder cell layer is desired, human embryonic stem (hES) cells can be maintained using Mouse Embryonic Fibroblast Conditioned Media (Catalog # AR005). The protocol below has been used with the BG01V line of hES cells. Please note that other hES cell lines may require modifications of this protocol. Optimal culture conditions must be determined by the investigator...

Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine1,2 of the IL-6 family. Although named for its ability to inhibit proliferation of the mouse myeloid leukemic cell line M1 by inducing differentiation,3 it also promotes survival and proliferation of other types of cells.1,2,4 An earlier report that LIF promotes the survival of primordial germ cells5 suggested a role in reproduction....

LYVE-1 (Lymphatic Vessel Endothelial Receptor 1) is a CD44 homolog found primarily on lymphatic endothelial cells.1 While LYVE-1 functions continue to be defined, potential roles have been suggested in hyaluronan (HA) transport and turnover, or in promoting HA localization to the surfaces of lymphatic endothelium. In addition, several studies have demonstrated the utility of LYVE-1 as a marker...