"CD3" has 55 results in Resources.

Tumors recruit immunosuppressive immune cells which create a microenvironment that inhibits anti-tumor responses and enables tumor growth. Monitoring the spatial and temporal dynamics of tumor infiltrating lymphocytes (TILs) and other immune cells in the tumor microenvironment is crucial for the development of more effective immune checkpoint blockade strategies. R&D Systems offers a wide...

Jinghua Wang, Guoping Wu, & Ruyi Hao ABSTRACT CD229/SLAMF3 is a transmembrane glycoprotein primarily found on mature T cells, B cells, myeloid cells, macrophages, and thymocytes. The functions of CD229 remain uncertain. Data from CD229 knockout mice indicate that CD229 is uniquely involved in enhancing T cell activation. However, co-ligation of CD229 and T cell receptor (TCR) using...

Request Mucosal Immunity of the Intestine Poster The intestinal lamina propria contains many types of myeloid and lymphoid cells that maintain tolerance or carry out inflammatory responses. Click on these tabs for flow cytometry phenotyping suggestions and extended lists of secreted, cell surface, and intracellular markers. Each link will direct you to our product offerings for the study...

The Cloudz T Cell Activation Kit - CD3/CD28 contains non-magnetic, dissolvable microparticles that are manufactured under GMP controls and conjugated with the common T cell-activating antibodies, CD3 and CD28. This kit improves T cell expansion and simplifies cell recovery for ex vivo manufacturing, while also providing safety and efficacy advantages over current bead-based T...

Isolate the cells you need for your adoptive cell transfer experiments with our Magcellect™ Cell Selection Kits. Using these kits, unwanted cells are magnetically tagged with a biotinylated antibody cocktail and streptavidin ferrofluid. The cell suspension is subsequently placed in a magnetic field, and the desired, untouched cell population of choice is harvested by aspiration and immediately...

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and it is characterized by uncontrolled growth and impaired differentiation of lymphoblasts. Although ALL is a heterogeneous disease, there are two major subtypes that are characterized by the type of leukemic cells present; either B cells (B-ALL) or T cells (T-ALL). Some instances of ALL are characterized by the presence of...

Activation of T cells is dependent on T cell receptors (TCR) and CD28, which recognize the Major Histocompatibility Complex (MHC) peptide and B7 family members, respectively, on Antigen Presenting Cells (APC). T cell antigen recognition is initiated by the MHC presenting a short peptide sequence which is recognized by T cells expressing a specific TCR. This initiating event is followed by...

Magnetic Beads in Cell Selection Procedures MagCellect Cell Isolation Kits Cell Types Species B Cells Human, Mouse, Rat TCells CD3 Human, Mouse CD4 Human, Mouse CD4 Naive Human, Mouse CD4 Memory Human CD8 Human, Mouse CD8 Naive Mouse Techniques to positively or negatively select...

D. Finkel, A. James, K. Brumbaugh, S. Dhawan, C. Goetz, J. Bonnevier and G. Wegner ABSTRACT Naïve T Helper cells can differentiate into Th1, Th2, and Th17 lineages each of which secrete a characteristic profile of molecules. In this study, we demonstrate the utility of antibody arrays to monitor T cell differentiation processes. Naïve T cells were isolated from PBMC preparations obtained...

Evidence is starting to suggest that memory T cells may be the most potent and effective subset to use for T cell therapy. Take advantage of the quality and selection of R&D Systems® and Novus Biologicals® antibodies to identify memory T cell subsets by flow cytometry. Refer to the tables below for the phenotypes of human and mouse memory T cell subsets and our selection of relevant flow...