"ahr" has 8 results in Resources.

T helper type 22 (Th22) cells are a subset of human CD4+ effector T cell that primarily secretes IL-22, IL-13, and TNF-alpha. Similar to Th17 cells, Th22 cells express IL-22, CCR4, and CCR6, but in contrast, they also express CCR10 and several fibroblast growth factors (FGFs). In addition, Th22 cells do not express IL-17, CCL20, IL-23 R, CD161 (Th17 markers), IL-4 (Th2 marker), or IFN-gamma (Th1...

Interleukin 13 (IL-13) is closely related to interleukin 4 (IL-4). They display overlapping functions, and the genes for the human proteins are both found on chromosome 5q. IL-13 is produced by activated Th0, Th1-like cells, Th2-like cells, and CD8-positive T cells. The mouse homolog is referred to as P600. IL-13 has multiple effects on the differentiation and functions of monocytes/macrophages....

CD4+ T cell subsets exert diverse functions due to their expression of characteristic cytokines. T helper type 22 (Th22) cells constitute one proinflammatory subset of CD4+ effector T cells that are characterized by the secretion of IL-10, IL-13, IL-22, and TNF-alpha. Th22 cells support mucosal immunity to microbial infection. Both circulating and local cell counts of Th22 cells can be...

Request Mucosal Immunity of the Intestine Poster The intestinal lamina propria contains many types of myeloid and lymphoid cells that maintain tolerance or carry out inflammatory responses. Click on these tabs for flow cytometry phenotyping suggestions and extended lists of secreted, cell surface, and intracellular markers. Each link will direct you to our product offerings for the study...

Click on these tabs for flow cytometry phenotyping suggestions and extended lists of secreted, cell surface, and intracellular markers. Each link will direct you to our product offerings for the study of these cells and molecules. For a broader representation of airway immunity, please view our poster Airway Inflammation in Asthma. Request Airway Inflammation in Asthma...

Review Group 1 ILCs Group 2 ILCs Group 3 ILCs Common Lymphoid progenitor Transcription factors Review Bordon, Y. (2014) Nat. Rev. Immunol. 14:133. Innate lymphoid cells: on the origin of ILCs. Colonna, M. (2013) Nature 498:42. Immunology: An innate regulatory cell. Cherrier, M. & Eberl, G. (2012) Curr. Opin. Immunol. 24: 178. The development of LTi cells. Cording, S. et...

A growing body of evidence suggests a pathogenic role for T helper 17 cells (Th17) in several autoim­mune diseases, including multiple sclerosis (MS). Th17 cells differentiate from naïve CD4+ lymphocytes in the presence of IL-6 and TGF-beta.1 Differentiation of Th17 cells also requires IL-21 for amplification of Th17 precursors, and IL-23 for stabilization and terminal differentiation of Th17...

Click on the tabs below for flow cytometry phenotyping suggestions and extended lists of secreted, cell surface, and intracellular markers. Each link will direct you to our product offerings for the study of these cells and molecules. For a broader representation of atherosclerosis, please view our poster Atherosclerosis Disease Progression. Request Poster   Myeloid...