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"cd40" has 40 results in Resources.

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Regulation of B Cell Activation and Homeostasis by TNF Superfamily Members

Research Areas

Several TNF superfamily members play key roles in early B cell maturation, homeostasis, differentiation, and activation. While BAFF R is required for normal B cell maturation, interactions between BAFF-BAFF R, BAFF-TACI, APRIL-BCMA, and CD40 Ligand-CD40 promote B cell differentiation and homeostasis. The interaction between CD40 Ligand and CD40 is necessary for germinal center B cell...

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TNF Superfamily Proteins

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We offer the widest selection high quality, bioactive TNF Superfamily proteins in the life sciences industry. These include an array of ligands and receptors, many of which are exclusive to R&D Systems. Click the buttons below to learn about our new and improved TNF Superfamily proteins. New Proteins Biotinylated Human TNF-alpha Human GMP-grade TNF-alpha Mouse DcTRAIL...

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Cancer Immunotherapy: Inducing Dendritic Cell Maturation

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Mature dendritic cells (DC) upregulate antigen presentation and co-stimulatory molecules on their surface as well as the production of inflammatory cytokines. This process can be induced by triggering receptors with cytokines, small molecules, or damage associated molecular patterns (DAMPs). It can be modulated by blocking the activity of molecules that normally inhibit DC maturation. Targeting...

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Assays for analytes represented in the Human Cardiac Panel A

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Analyte Quantikine® ELISA Kit DuoSet® ELISA Development System CD40 Ligand DCDL40 DY617 GDF-15 DGD150 DY957 Pappalysin-1/PAPP-A DPPA00   Proprotein Convertase 9/PCSK9 DPC900   ST2/IL-1R4 DST200 DY523 TNF RII DRT200 DY726

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Luminex Analytes by Research Topic

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Adipokine/Obesity Angiogenesis Bone Proteins Cardiovascular Disease CD8+ T cell Chemokines Complement Inflammation Kidney Biomarker Liver Proteins Myokines Neurodegenerative Disorders Neurological Disorders Neurological Panel Oncology Proteases Protease Inhibitors Sepsis Soluble Receptors Soluble Receptors, Hematopoietic Soluble Receptors,...

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Assays for analytes represented in the Human Cytokine Panel B

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Analyte Quantikine® ELISA Kit Quantikine® HS (High Sensitivity) ELISA Kit DuoSet® Development ELISA System CCL11/Eotaxin DTX00   DY320 CD40...

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Regulation of Natural Killer Cell Co-stimulation by TNF Superfamily Members

Research Areas

Upon activation, natural killer (NK) cells secrete cytotoxic and inflammatory cytokines that cause apoptosis or lysis of targeted cells. While some pathogens can directly activate NK cells, NK cells are indirectly activated in response to most pathogens by accessory cells. Several TNF superfamily members have been implicated in mediating NK cell activation and regulation by accessory cells. These...

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Human Soluble Receptor Array Kit Hematopoietic Panel

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Human sReceptor Array Kit Hematopoietic Panel Ordering Information Introduction R&D Systems Human Soluble Receptor Array Kit Hematopoietic Panel (Catalog # ARY011) is a rapid, sensitive, and economical tool used to simultaneously detect the relative levels of 105 different soluble receptors expressed and released by hematopoietic cells in a single sample. No specialized equipment is...

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Human Soluble Receptor Array Kit Non-Hematopoietic Panel

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Human sReceptor Array Kit Non-Hematopoietic Panel Ordering Information Introduction R&D Systems Human Soluble Receptor Array Kit Non-Hematopoietic Panel (Catalog # ARY012) is a rapid, sensitive, and economical tool used to simultaneously detect the relative levels of 119 different soluble receptors expressed and released by non-hematopoietic cells in a single sample. No specialized...

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Assays for analytes represented in the Human Hematopoeitic Array

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Analyte DuoSet® and DuoSet IC ELISA Development Systems Quantikine® ELISA...

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