"mkk" has 6 results in Resources.

Featured Literature Pattern Recognition Receptors and the Innate Immune Response Poster View Poster Featured Products Pattern Recognition Receptors Brochure View Brochure   Overview of Toll-like Receptors Toll-like receptors (TLRs) are a family of transmembrane pattern recognition receptors that detect invading pathogens and initiate the...

Featured Literature Inflammasomes: Intracellular Regulators of Pathogen Recognition, Host Defense, and Inflammation Poster View Poster Featured Products Pattern Recognition Receptors Brochure View Brochure   Overview of NOD-like Receptors Nucleotide-binding, oligomerization domain (NOD)-like receptors (NLRs) are a family of cytosolic...

Analyte DuoSet® IC ELISA Development System (Total) DuoSet® IC ELISA Development Systems (Phospho) Akt1 (S473) DYC1775 DYC2289C Akt2 (S474) DYC2315   Akt3 (S472)     Akt pan (S473, S474, S472)   DYC887B CREB (S133)   DYC2510 ERK1 (T202/Y204) DYC1940 DYC1825 ERK2...

Human Phospho-MAPK Array Kit Ordering Information Introduction The Human Phospho-Mitogen-activated Protein Kinase (MAPK) Antibody Array (Catalog # ARY002B) is an economical tool used to simultaneously detect the relative phosphorylation of 24 kinases without performing numerous immunoprecipitation and/or Western blots. Kinases are captured by 26 different antibodies spotted in duplicate on...

The major output of MAPK signaling downstream of inflammatory cytokines is a proinflammatory response. TNF Receptor (TNFR) activation by TNF superfamily ligands leads to recruitment of TRAF-2, TRAF-3, TRAF-6, and IKK gamma to the TNFR complex. TRAF-2 and TRAF-6 are subsequently auto-polyubiquitinated with Lys63-linked chains in a Ubc13-Uev1a-dependent manner. Ubiquitinated TRAF-2 and TRAF-6...

Its Role in Growth Factor Signaling and Cancer Contents Upstream from ERK The Core Module Downstream from ERK Conclusions References Growth factors, through receptor tyrosine kinases, recruit a large network of signaling proteins to execute their cellular programs. The first of these networks to be discovered was the Ras-Raf-ERK signal transduction cascade, defined by Extracellular...