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193 D7

Catalog #: 8167 Datasheet / COA / SDS
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193 D7 | CAS No. 861224-48-8 | Histone Demethylase Inhibitors
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Description: JMJD1C inhibitor

Chemical Name: 8-Benzoyl-2,3,6,7-tetrahydro-5-oxo-5H-thiazolo[3,2-a]pyridine-6-acetic acid

Purity: ≥98%

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Biological Activity

193 D7 is a histone demethylase JMJD1C inhibitor (IC50 = 0.59 μM in in vitro demethylation assay). In vivo, 193 D7 suppresses tumor by targeting intratumoral Treg cells in mice tumor models. 193 D7 is orally bioavailable.

Technical Data

M.Wt:
317.36
Formula:
C16H15NO4S
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
861224-48-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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