2-Methylthioadenosine triphosphate tetrasodium salt
Chemical Name: 2-Methylthioadenosine-5'-triphosphate tetrasodium salt
Purity: ≥98%
Biological Activity
2-Methylthioadenosine triphosphate tetrasodium salt is a P2 purinoceptor agonist.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Adenosine A2B receptor-mediated leukemia inhibitory factor release from astrocytes protects cortical neurons against excitotoxicity.
Moidunny S, Vinet J
J Neuroinflammation, 2012;9(1):198. -
Specific but non-competitive inhibition by 2-alkylthioanalogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate.
Cusack et al.
Br.J.Pharmacol., 1982;75:397 -
Studies on the stereoselectivity of the P2-purinoreceptor.
Burnstock et al.
Br.J.Pharmacol., 1983;79:907 -
International Union of Pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits.
Khakh et al.
Pharmacol.Rev., 2001;53:107 -
Purinoceptor subtypes mediating contraction and relaxation of marmoset urinary bladder smooth muscle.
McMurray et al.
Br.J.Pharmacol., 1998;123:1579
Product Datasheets
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Citations for 2-Methylthioadenosine triphosphate tetrasodium salt
The citations listed below are publications that use Tocris products. Selected citations for 2-Methylthioadenosine triphosphate tetrasodium salt include:
3 Citations: Showing 1 - 3
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Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia.
Authors: Nagai Et al.
EBioMedicine 2017;24:147
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Purinergic and Cholinergic Drugs Mediate Hyperventilation in Zebrafish: Evidence from a Novel Chemical Screen.
Authors: Rahbar Et al.
Nature 2016;11:e0154261
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Agonist-bound structure of the human P2Y12 receptor.
Authors: Zhang Et al.
Med J Islam Repub Iran 2014;509:119
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